HU9600612D0 - Improved pharmaceutical formulation - Google Patents
Improved pharmaceutical formulationInfo
- Publication number
- HU9600612D0 HU9600612D0 HU9600612A HU9600612A HU9600612D0 HU 9600612 D0 HU9600612 D0 HU 9600612D0 HU 9600612 A HU9600612 A HU 9600612A HU 9600612 A HU9600612 A HU 9600612A HU 9600612 D0 HU9600612 D0 HU 9600612D0
- Authority
- HU
- Hungary
- Prior art keywords
- compositions
- cyclodextrin
- cytotoxic
- ulceration
- compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11672493A | 1993-09-03 | 1993-09-03 | |
| US08/297,249 US5602112A (en) | 1992-06-19 | 1994-08-26 | Pharmaceutical formulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU9600612D0 true HU9600612D0 (en) | 1996-05-28 |
| HUT73778A HUT73778A (en) | 1996-09-30 |
Family
ID=26814548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9600612A HUT73778A (en) | 1993-09-03 | 1994-09-02 | Improved pharmaceutical formulation |
Country Status (13)
| Country | Link |
|---|---|
| US (6) | US5602112A (hu) |
| EP (1) | EP0717638B1 (hu) |
| JP (1) | JPH09502185A (hu) |
| AT (1) | ATE214290T1 (hu) |
| AU (1) | AU7718694A (hu) |
| CA (1) | CA2172159C (hu) |
| DE (1) | DE69430126T2 (hu) |
| DK (1) | DK0717638T3 (hu) |
| ES (1) | ES2171462T3 (hu) |
| HU (1) | HUT73778A (hu) |
| IL (1) | IL110825A0 (hu) |
| PT (1) | PT717638E (hu) |
| WO (1) | WO1995006485A1 (hu) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040014695A1 (en) * | 1992-06-19 | 2004-01-22 | Supergen, Inc. | Pharmaceutical formulation |
| US5602112A (en) * | 1992-06-19 | 1997-02-11 | Supergen, Inc. | Pharmaceutical formulation |
| ATE241984T1 (de) * | 1993-03-26 | 2003-06-15 | Franciscus Wilhelmus He Merkus | Pharmazeutische zusammensetzungen zur intranasalen verabreichung von apomorphin |
| ATE302599T1 (de) | 1996-05-24 | 2005-09-15 | Angiotech Pharm Inc | Zubereitungen und verfahren zur behandlung oder prävention von krankheiten der körperpassagewege |
| AU741439B2 (en) | 1996-12-30 | 2001-11-29 | Battelle Memorial Institute | Formulation and method for treating neoplasms by inhalation |
| US6566353B2 (en) * | 1996-12-30 | 2003-05-20 | Bone Care International, Inc. | Method of treating malignancy associated hypercalcemia using active vitamin D analogues |
| HUP9701945A3 (en) * | 1997-11-10 | 2000-04-28 | Hexal Ag | Pharmaceutical composition for injection containing cyclodextrin and taxoids |
| US6713454B1 (en) | 1999-09-13 | 2004-03-30 | Nobex Corporation | Prodrugs of etoposide and etoposide analogs |
| GB9921954D0 (en) * | 1999-09-16 | 1999-11-17 | Pharmacia & Upjohn Spa | Formulations for parenteral use of estramustine phosphate with improved pharmacological properties |
| GB9921958D0 (en) * | 1999-09-16 | 1999-11-17 | Pharmacia & Upjohn Spa | Formulations for parenteral use of estramustine phosphate and sulfoalkylether-cyclodextrins |
| WO2001083520A2 (en) * | 2000-05-02 | 2001-11-08 | Theravance,Inc | Polyacid glycopeptide derivatives |
| ATE416791T1 (de) | 2000-05-02 | 2008-12-15 | Theravance Inc | Zusammensetzung die eine zyklodextrin und ein glykopeptid-antibiotikum enthält |
| UA75083C2 (uk) * | 2000-06-22 | 2006-03-15 | Тераванс, Інк. | Похідні глікопептидфосфонатів |
| US6872804B2 (en) * | 2000-06-22 | 2005-03-29 | Theravance, Inc. | Glycopeptide disulfide and thioester derivatives |
| AU2001259303A1 (en) * | 2000-06-22 | 2002-01-02 | Advanced Medicine, Inc. | Glycopeptide carboxy-saccharide derivatives |
| AU2001259816A1 (en) | 2000-06-22 | 2002-01-02 | Advanced Medecine, Inc. | Polyhydroxy glycopeptide derivatives |
| US6468989B1 (en) * | 2000-07-13 | 2002-10-22 | Dow Pharmaceutical Sciences | Gel compositions containing metronidazole |
| PE20020300A1 (es) * | 2000-08-22 | 2002-05-10 | Pharmacia Corp | Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco |
| IT1318689B1 (it) * | 2000-09-12 | 2003-08-27 | Pharmacia & Upjohn Spa | Uso dell'arginina nella preparazione di un medicamento per lapreparazione e trattamento degli effetti collaterali associati alla |
| US6884885B2 (en) * | 2000-12-21 | 2005-04-26 | Cerestar Holding B.V. | Production of cyclodextrin complexes |
| EP1389090A2 (en) * | 2001-04-26 | 2004-02-18 | Board of Regents, The University of Texas System | Diagnostic imaging compositions, their methods of synthesis and use |
| US6528076B2 (en) | 2001-07-06 | 2003-03-04 | Magic Herb Corp. | Topical compositions and methods for treating pain |
| GB0127677D0 (en) * | 2001-11-19 | 2002-01-09 | Vianex S A | Inclusion complex |
| US7261875B2 (en) * | 2001-12-21 | 2007-08-28 | Board Of Regents, The University Of Texas System | Dendritic poly (amino acid) carriers and methods of use |
| US6828311B2 (en) | 2002-05-29 | 2004-12-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Formulation for the parenteral application of a sodium channel blocker |
| BR0314068A (pt) * | 2002-09-05 | 2005-07-05 | Bharat Serums & Vaccines Ltd | Processo para a preparação de uma composição estável com baixo nìvel de toxicidade; composição estável que contém oxazafosforina; uso de uma composição estável que contém oxazafosforina; e método de tratamento de uma doença maligna |
| US7157446B2 (en) * | 2003-05-02 | 2007-01-02 | Bristol Myers Squibb Company | Complex of ras-farnesyltransferase inhibitor, a cyclodextrin, and ethanol |
| CA2554346C (en) * | 2004-01-30 | 2009-11-17 | Pfizer Products Inc. | Parenteral formulations comprising a beta-cyclodextrin and a preservative |
| AU2006341131A1 (en) * | 2005-10-14 | 2007-10-04 | Janssen Pharmaceutica, N.V. | Formulations of tipifarnib for intravenous administration |
| CN100411688C (zh) * | 2006-09-12 | 2008-08-20 | 南京师范大学 | 含有环糊精/多烯紫杉醇包合物的药物组合物及其制备方法 |
| CN100486645C (zh) * | 2006-09-12 | 2009-05-13 | 南京师范大学 | 含有环糊精紫杉醇包合物的药物组合物及其制备方法 |
| WO2008067027A2 (en) | 2006-10-20 | 2008-06-05 | Icos Corporation | Compositions of chkl inhibitors and cyclodextrin |
| WO2009132352A1 (en) * | 2008-04-25 | 2009-10-29 | Rhode Island Hospital | Active sunscreen composition |
| ES2525257T3 (es) | 2009-02-25 | 2014-12-19 | Supratek Pharma, Inc. | Composiciones de ciclopolisacárido y de bendamustina |
| US11020363B2 (en) | 2009-05-29 | 2021-06-01 | Cydex Pharmaceuticals, Inc. | Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same |
| WO2010138920A1 (en) | 2009-05-29 | 2010-12-02 | Cydex Pharmaceuticals, Inc. | Injectable melphalan compositions comprising a cyclodextrin derivative and methods of making and using the same |
| US20110015245A1 (en) * | 2009-07-20 | 2011-01-20 | Valery Alakhov | Bendamustine amphiphilic cationic compositions |
| US8389558B2 (en) * | 2009-07-20 | 2013-03-05 | Supratek Pharma Inc. | Bendamustine amphiphilic anionic compositions |
| TWI438009B (zh) * | 2010-02-19 | 2014-05-21 | Teikoku Pharma Usa Inc | 紫杉烷前－乳劑調配物及其製造與使用之方法 |
| WO2011139899A2 (en) | 2010-05-03 | 2011-11-10 | Teikoku Pharma Usa, Inc. | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
| US8383663B2 (en) | 2010-07-19 | 2013-02-26 | Supratek Pharma Inc. | Bendamustine anionic-catioinic cyclopolysaccharide compositions |
| WO2013040286A2 (en) * | 2011-09-18 | 2013-03-21 | Euro-Celtique S.A. | Pharmaceutical compositions |
| TWI573792B (zh) | 2012-02-01 | 2017-03-11 | 歐陸斯迪公司 | 新穎治療劑 |
| JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
| CA2919837A1 (en) * | 2013-08-02 | 2015-02-05 | Children's Hospital Medical Center | Compositions and methods for treating disease states associated with activated t cells and/or b cells |
| WO2015061206A2 (en) | 2013-10-21 | 2015-04-30 | North Carolina State University | Methods and constructs for compound delivery |
| RU2587716C2 (ru) * | 2014-01-14 | 2016-06-20 | Борис Игоревич Круглый | Стабильный фармацевтический состав на основе актиномицина д для инъекций |
| GB201409471D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| GB201409488D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| GB201409485D0 (en) | 2014-05-28 | 2014-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| WO2018068832A1 (en) | 2016-10-11 | 2018-04-19 | Euro-Celtique S.A. | Hodgkin lymphoma therapy |
| GB201709403D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating sarcoma |
| GB201709406D0 (en) | 2017-06-13 | 2017-07-26 | Euro-Cletique S A | Compounds for treating TNBC |
| GB201709405D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating ovarian cancer |
| GB201709402D0 (en) | 2017-06-13 | 2017-07-26 | Euro Celtique Sa | Compounds for treating t-pll |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5735189B2 (hu) * | 1972-01-06 | 1982-07-27 | ||
| US4024223A (en) * | 1972-11-11 | 1977-05-17 | Teijin Limited | Stripe composition and method of reducing smell associated therewith |
| JPS53136513A (en) * | 1977-05-06 | 1978-11-29 | Ono Pharmaceut Co Ltd | Stabilization of prostaglandin-x-related compounds |
| HU176215B (en) * | 1978-01-27 | 1981-01-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing a cyclodextrin-indomethacin inclusion complex with a ratio of at about 2:1 |
| JPS54115368A (en) * | 1978-03-01 | 1979-09-07 | Ono Pharmaceut Co Ltd | Prostaglandin i2 analog, its preparation, and drug composition containing it as active constituent |
| IT1113341B (it) * | 1978-03-31 | 1986-01-20 | Ono Pharmaceutical Co | Analoghi della 6,9-metano-pgi2 |
| US4352793A (en) * | 1979-04-26 | 1982-10-05 | Sumitomo Chemical Company, Limited | Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin |
| JPS6033430B2 (ja) * | 1980-05-12 | 1985-08-02 | 小野薬品工業株式会社 | プロスタグランジン類似化合物 |
| ZA82447B (en) * | 1981-01-23 | 1983-09-28 | Wellcome Found | Chemical complex |
| JPS5813541A (ja) * | 1981-07-16 | 1983-01-26 | Kureha Chem Ind Co Ltd | エイコサペンタエン酸又はドコサヘキサエン酸のシクロデキストリン包接化合物 |
| US4407795A (en) * | 1981-07-16 | 1983-10-04 | American Cyanamid Company | Inclusion compound of p-hexadecylamino benzoic acid in cyclodextrin and method of use |
| JPS5838250A (ja) * | 1981-09-01 | 1983-03-05 | Teikoku Chem Ind Corp Ltd | 複合体 |
| JPS58126810A (ja) * | 1981-12-24 | 1983-07-28 | Kaken Pharmaceut Co Ltd | 抗炎症眼科用液剤およびその製法 |
| US4383992A (en) * | 1982-02-08 | 1983-05-17 | Lipari John M | Water-soluble steroid compounds |
| JPS58177949A (ja) * | 1982-04-12 | 1983-10-18 | Takeda Chem Ind Ltd | ランカシジン群抗生物質包接化合物 |
| DE3315356A1 (de) * | 1982-04-30 | 1983-11-17 | Ono Pharmaceutical Co. Ltd., Osaka | Verwendung von prostaglandinanalogen |
| US4659696A (en) * | 1982-04-30 | 1987-04-21 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition and its nasal or vaginal use |
| US4425336A (en) * | 1982-05-24 | 1984-01-10 | Key Pharmaceuticals, Inc. | 3,4-Dihydroxy-N-[3-(4-dihydroxyphenyl)-1-methyl-n-propyl]-beta-phenethylamine cyclodextrin complexes |
| US4424209A (en) * | 1982-06-21 | 1984-01-03 | Key Pharmaceuticals, Inc. | 3,4-Di-isobutyryloxy-N- 3-(4-isobutyryloxyphenyl)-1-methyl-n-propyl!-beta-phenethylamine cyclodextrin complexes |
| JPS5910510A (ja) * | 1982-07-08 | 1984-01-20 | Nippon Zenyaku Kogyo Kk | 低刺激性チアムリン注射剤 |
| JPS5920230A (ja) * | 1982-07-19 | 1984-02-01 | チバ−ガイギ−・アクチエンゲゼルシヤフト | ピルプロフエン含有薬剤 |
| HU190818B (en) * | 1982-11-09 | 1986-11-28 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu | Process for producing complexes of piperonyl-butoxide-cyclodextrin |
| JPS6025967A (ja) * | 1983-07-21 | 1985-02-08 | Eisai Co Ltd | トリパミド包接化合物 |
| US4751095A (en) * | 1983-07-28 | 1988-06-14 | Karl Curtis L | Aspartame stabilization with cyclodextrin |
| JPS6081166A (ja) * | 1983-10-11 | 1985-05-09 | Fujisawa Pharmaceut Co Ltd | ２−ニトロオキシメチル−６−クロロピリジンのβ−シクロデキストリン包接化合物およびその製造法 |
| IT1196033B (it) * | 1984-02-22 | 1988-11-10 | Chiesi Farma Spa | Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche |
| US4675395A (en) * | 1984-03-14 | 1987-06-23 | Seiwa Technological Laboratories Limited | Cyclodextrin inclusion compound and process for its preparation |
| US4727064A (en) * | 1984-04-25 | 1988-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Pharmaceutical preparations containing cyclodextrin derivatives |
| US4596795A (en) * | 1984-04-25 | 1986-06-24 | The United States Of America As Represented By The Secretary, Dept. Of Health & Human Services | Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives |
| JPS61207380A (ja) * | 1985-03-11 | 1986-09-13 | Taiyo Yakuhin Kogyo Kk | モベンゾキサミンの経口製剤 |
| JPS61286318A (ja) * | 1985-06-13 | 1986-12-16 | Ichiro Shibauchi | 浴剤の製造方法 |
| US4663316A (en) * | 1985-06-28 | 1987-05-05 | Warner-Lambert Company | Antibiotic clathrates and pharmaceutical compositions thereof |
| US4728509A (en) * | 1985-08-19 | 1988-03-01 | Takeda Chemical Industries, Ltd. | Aqueous liquid preparation |
| US4623641A (en) * | 1985-09-09 | 1986-11-18 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. | Method of treating ulcers and erosions in the gastrointestinal system using PGI2 -methyl ester-beta cyclodextrin inclusion complexes |
| US5002935A (en) * | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
| JP3176716B2 (ja) * | 1991-06-21 | 2001-06-18 | 武田薬品工業株式会社 | 溶解性が向上した難水溶性薬物組成物 |
| EP0519428B1 (en) * | 1991-06-21 | 2000-09-20 | Takeda Chemical Industries, Ltd. | Cyclodextrin compositions with fumagillol derivates |
| US5602112A (en) * | 1992-06-19 | 1997-02-11 | Supergen, Inc. | Pharmaceutical formulation |
| JPH06157330A (ja) * | 1992-11-27 | 1994-06-03 | Ensuiko Sugar Refining Co Ltd | タキソールのサイクロデキストリン包接物，その製造法と用途 |
-
1994
- 1994-08-26 US US08/297,249 patent/US5602112A/en not_active Expired - Lifetime
- 1994-08-30 IL IL11082594A patent/IL110825A0/xx unknown
- 1994-09-02 DK DK94927983T patent/DK0717638T3/da active
- 1994-09-02 DE DE69430126T patent/DE69430126T2/de not_active Expired - Fee Related
- 1994-09-02 AT AT94927983T patent/ATE214290T1/de active
- 1994-09-02 ES ES94927983T patent/ES2171462T3/es not_active Expired - Lifetime
- 1994-09-02 AU AU77186/94A patent/AU7718694A/en not_active Abandoned
- 1994-09-02 WO PCT/US1994/009879 patent/WO1995006485A1/en active IP Right Grant
- 1994-09-02 HU HU9600612A patent/HUT73778A/hu unknown
- 1994-09-02 JP JP7508268A patent/JPH09502185A/ja active Pending
- 1994-09-02 CA CA002172159A patent/CA2172159C/en not_active Expired - Fee Related
- 1994-09-02 EP EP94927983A patent/EP0717638B1/en not_active Expired - Lifetime
- 1994-09-02 PT PT94927983T patent/PT717638E/pt unknown
-
1997
- 1997-02-03 US US08/790,223 patent/US5804568A/en not_active Expired - Lifetime
-
1998
- 1998-08-28 US US09/143,412 patent/US6048845A/en not_active Expired - Lifetime
-
1999
- 1999-07-02 US US09/347,096 patent/US6218374B1/en not_active Expired - Fee Related
-
2000
- 2000-10-05 US US09/684,375 patent/US6284747B1/en not_active Expired - Fee Related
-
2001
- 2001-08-23 US US09/938,473 patent/US6583125B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1995006485A1 (en) | 1995-03-09 |
| US20020058634A1 (en) | 2002-05-16 |
| US6048845A (en) | 2000-04-11 |
| US6284747B1 (en) | 2001-09-04 |
| US6218374B1 (en) | 2001-04-17 |
| AU7718694A (en) | 1995-03-22 |
| DK0717638T3 (da) | 2002-07-01 |
| ATE214290T1 (de) | 2002-03-15 |
| HUT73778A (en) | 1996-09-30 |
| JPH09502185A (ja) | 1997-03-04 |
| CA2172159C (en) | 2003-07-29 |
| EP0717638A1 (en) | 1996-06-26 |
| US6583125B2 (en) | 2003-06-24 |
| DE69430126T2 (de) | 2002-08-01 |
| ES2171462T3 (es) | 2002-09-16 |
| CA2172159A1 (en) | 1995-03-09 |
| DE69430126D1 (de) | 2002-04-18 |
| EP0717638B1 (en) | 2002-03-13 |
| IL110825A0 (en) | 1995-05-26 |
| US5602112A (en) | 1997-02-11 |
| US5804568A (en) | 1998-09-08 |
| PT717638E (pt) | 2002-07-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DFC4 | Cancellation of temporary protection due to refusal |