HU217668B - Optikailag aktív imidazolidinonszármazékok és ezeket tartalmazó gyógyászati készítmények - Google Patents
Optikailag aktív imidazolidinonszármazékok és ezeket tartalmazó gyógyászati készítmények Download PDFInfo
- Publication number
- HU217668B HU217668B HU9600622A HU9600622A HU217668B HU 217668 B HU217668 B HU 217668B HU 9600622 A HU9600622 A HU 9600622A HU 9600622 A HU9600622 A HU 9600622A HU 217668 B HU217668 B HU 217668B
- Authority
- HU
- Hungary
- Prior art keywords
- halogen
- formula
- phenylmethyl
- compound
- imidazolidinone
- Prior art date
Links
- 0 CN(CCC1)C[C@@]1NC(*)=O Chemical compound CN(CCC1)C[C@@]1NC(*)=O 0.000 description 2
- QZSACHHNFDNCNB-ZCFIWIBFSA-N CN(CCC1)C[C@@H]1N Chemical compound CN(CCC1)C[C@@H]1N QZSACHHNFDNCNB-ZCFIWIBFSA-N 0.000 description 1
- YDFGOGVLNOLUSB-MRVPVSSYSA-N CN(CCC1)C[C@@H]1N(CCN1)[NH+]1[O-] Chemical compound CN(CCC1)C[C@@H]1N(CCN1)[NH+]1[O-] YDFGOGVLNOLUSB-MRVPVSSYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25498393 | 1993-09-17 | ||
| JP24226494A JP3916093B2 (ja) | 1993-09-17 | 1994-09-09 | 光学活性イミダゾリジノン誘導体とその製造方法 |
| PCT/JP1994/001505 WO1995007905A1 (fr) | 1993-09-17 | 1994-09-12 | Derive d'imidazolidinone et procede pour sa production |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9600622D0 HU9600622D0 (en) | 1996-05-28 |
| HUT75649A HUT75649A (en) | 1997-05-28 |
| HU217668B true HU217668B (hu) | 2000-03-28 |
Family
ID=26535688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9600622A HU217668B (hu) | 1993-09-17 | 1994-09-12 | Optikailag aktív imidazolidinonszármazékok és ezeket tartalmazó gyógyászati készítmények |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5726188A (fr) |
| EP (1) | EP0719772B1 (fr) |
| JP (1) | JP3916093B2 (fr) |
| KR (1) | KR100323930B1 (fr) |
| CN (1) | CN1041088C (fr) |
| AT (1) | ATE194611T1 (fr) |
| AU (1) | AU679259B2 (fr) |
| CA (1) | CA2172162C (fr) |
| DE (1) | DE69425266T2 (fr) |
| DK (1) | DK0719772T3 (fr) |
| ES (1) | ES2149281T3 (fr) |
| GR (1) | GR3034499T3 (fr) |
| HU (1) | HU217668B (fr) |
| PT (1) | PT719772E (fr) |
| WO (1) | WO1995007905A1 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09504272A (ja) * | 1993-09-15 | 1997-04-28 | メルク シヤープ エンド ドーム リミテツド | ドーパミンアンタゴニストとしてのイミダゾロン及びオキサゾロン誘導体 |
| US6159990A (en) * | 1997-06-18 | 2000-12-12 | Synaptic Pharmaceutical Corporation | Oxazolidinones as α1A receptor antagonists |
| US6316623B1 (en) * | 1998-08-21 | 2001-11-13 | Isis Pharmaceuticals, Inc. | Ethylenediamine compound libraries |
| US6951849B2 (en) * | 2001-10-02 | 2005-10-04 | Acadia Pharmaceuticals Inc. | Benzimidazolidinone derivatives as muscarinic agents |
| RU2288919C2 (ru) * | 2001-10-02 | 2006-12-10 | Акадиа Фармасьютикалз, Инк. | Производные бензимидазолидинона в качестве агентов мускариновых рецепторов |
| JP5209479B2 (ja) * | 2005-09-30 | 2013-06-12 | グラクソ グループ リミテッド | Ｍ１受容体にて活性を有するベンゾイミダゾロン類 |
| US8288412B2 (en) * | 2005-09-30 | 2012-10-16 | Glaxo Group Limited | Compounds which have activity at M1 receptor and their uses in medicine |
| DE602006019119D1 (de) * | 2005-09-30 | 2011-02-03 | Glaxo Group Ltd | Verbindungen mit aktivität am m1-rezeptor und ihre verwendung in der medizin |
| JP5265513B2 (ja) | 2007-02-19 | 2013-08-14 | 株式会社カネカ | 光学活性３−アミノピペリジン又はその塩の製造方法 |
| WO2011010579A1 (fr) * | 2009-07-21 | 2011-01-27 | 住友化学株式会社 | Procédé pour la production de nipecotamide optiquement actif |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3196152A (en) * | 1965-07-20 | Phenyl and alkyleneamino substituted imidazolidinones and salts thereof | ||
| US459757A (en) * | 1891-09-22 | Electric-arc lamp | ||
| US3355457A (en) * | 1965-05-21 | 1967-11-28 | American Cyanamid Co | Substituted 2-imidazolinones |
| US3459757A (en) * | 1965-10-22 | 1969-08-05 | American Cyanamid Co | Imidazolidines |
| US4011238A (en) * | 1972-07-26 | 1977-03-08 | Gruppo Lepetit S.P.A. | 2-imidazolidione derivatives |
| GB9106571D0 (en) * | 1991-03-27 | 1991-05-15 | Erba Carlo Spa | Derivatives of substituted imidazol-2-one and process for their preparation |
| US5300515A (en) * | 1991-01-31 | 1994-04-05 | Kyorin Pharmaceutical Co., Ltd. | Carbamic acid derivatives and method for preparing the same |
| JPH09504272A (ja) * | 1993-09-15 | 1997-04-28 | メルク シヤープ エンド ドーム リミテツド | ドーパミンアンタゴニストとしてのイミダゾロン及びオキサゾロン誘導体 |
-
1994
- 1994-09-09 JP JP24226494A patent/JP3916093B2/ja not_active Expired - Fee Related
- 1994-09-12 DK DK94926387T patent/DK0719772T3/da active
- 1994-09-12 DE DE69425266T patent/DE69425266T2/de not_active Expired - Fee Related
- 1994-09-12 EP EP94926387A patent/EP0719772B1/fr not_active Expired - Lifetime
- 1994-09-12 AT AT94926387T patent/ATE194611T1/de not_active IP Right Cessation
- 1994-09-12 HU HU9600622A patent/HU217668B/hu not_active IP Right Cessation
- 1994-09-12 AU AU76243/94A patent/AU679259B2/en not_active Ceased
- 1994-09-12 KR KR1019960701412A patent/KR100323930B1/ko not_active IP Right Cessation
- 1994-09-12 ES ES94926387T patent/ES2149281T3/es not_active Expired - Lifetime
- 1994-09-12 CA CA002172162A patent/CA2172162C/fr not_active Expired - Fee Related
- 1994-09-12 WO PCT/JP1994/001505 patent/WO1995007905A1/fr active IP Right Grant
- 1994-09-12 US US08/612,827 patent/US5726188A/en not_active Expired - Fee Related
- 1994-09-12 CN CN94194134A patent/CN1041088C/zh not_active Expired - Fee Related
- 1994-09-12 PT PT94926387T patent/PT719772E/pt unknown
-
2000
- 2000-09-28 GR GR20000402189T patent/GR3034499T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US5726188A (en) | 1998-03-10 |
| CA2172162A1 (fr) | 1995-03-23 |
| HUT75649A (en) | 1997-05-28 |
| ATE194611T1 (de) | 2000-07-15 |
| HU9600622D0 (en) | 1996-05-28 |
| PT719772E (pt) | 2000-11-30 |
| EP0719772B1 (fr) | 2000-07-12 |
| ES2149281T3 (es) | 2000-11-01 |
| CN1041088C (zh) | 1998-12-09 |
| DK0719772T3 (da) | 2000-11-06 |
| EP0719772A1 (fr) | 1996-07-03 |
| EP0719772A4 (fr) | 1996-09-04 |
| JPH07133273A (ja) | 1995-05-23 |
| KR100323930B1 (ko) | 2004-05-06 |
| WO1995007905A1 (fr) | 1995-03-23 |
| CN1135216A (zh) | 1996-11-06 |
| DE69425266T2 (de) | 2001-02-22 |
| AU679259B2 (en) | 1997-06-26 |
| KR960704878A (ko) | 1996-10-09 |
| JP3916093B2 (ja) | 2007-05-16 |
| CA2172162C (fr) | 2005-04-19 |
| DE69425266D1 (de) | 2000-08-17 |
| AU7624394A (en) | 1995-04-03 |
| GR3034499T3 (en) | 2000-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of definitive patent protection due to non-payment of fees |