DE69425266T2 - Optisch aktive imidazolidinon-derivate und verfahren zu deren herstellung - Google Patents

Optisch aktive imidazolidinon-derivate und verfahren zu deren herstellung

Info

Publication number
DE69425266T2
DE69425266T2 DE69425266T DE69425266T DE69425266T2 DE 69425266 T2 DE69425266 T2 DE 69425266T2 DE 69425266 T DE69425266 T DE 69425266T DE 69425266 T DE69425266 T DE 69425266T DE 69425266 T2 DE69425266 T2 DE 69425266T2
Authority
DE
Germany
Prior art keywords
optically active
production
active imidazolidinone
same
imidazolidinone derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69425266T
Other languages
English (en)
Other versions
DE69425266D1 (de
Inventor
Yasuo Takano
Kei Okazaki
Takashi Hirayama
Tsuyoshi Anraku
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Publication of DE69425266D1 publication Critical patent/DE69425266D1/de
Application granted granted Critical
Publication of DE69425266T2 publication Critical patent/DE69425266T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
DE69425266T 1993-09-17 1994-09-12 Optisch aktive imidazolidinon-derivate und verfahren zu deren herstellung Expired - Fee Related DE69425266T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP25498393 1993-09-17
JP24226494A JP3916093B2 (ja) 1993-09-17 1994-09-09 光学活性イミダゾリジノン誘導体とその製造方法
PCT/JP1994/001505 WO1995007905A1 (fr) 1993-09-17 1994-09-12 Derive d'imidazolidinone et procede pour sa production

Publications (2)

Publication Number Publication Date
DE69425266D1 DE69425266D1 (de) 2000-08-17
DE69425266T2 true DE69425266T2 (de) 2001-02-22

Family

ID=26535688

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69425266T Expired - Fee Related DE69425266T2 (de) 1993-09-17 1994-09-12 Optisch aktive imidazolidinon-derivate und verfahren zu deren herstellung

Country Status (15)

Country Link
US (1) US5726188A (de)
EP (1) EP0719772B1 (de)
JP (1) JP3916093B2 (de)
KR (1) KR100323930B1 (de)
CN (1) CN1041088C (de)
AT (1) ATE194611T1 (de)
AU (1) AU679259B2 (de)
CA (1) CA2172162C (de)
DE (1) DE69425266T2 (de)
DK (1) DK0719772T3 (de)
ES (1) ES2149281T3 (de)
GR (1) GR3034499T3 (de)
HU (1) HU217668B (de)
PT (1) PT719772E (de)
WO (1) WO1995007905A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU682889B2 (en) * 1993-09-15 1997-10-23 Merck Sharp & Dohme Limited Imidazolone and oxazolone derivatives as dopamine antagonists
US6159990A (en) 1997-06-18 2000-12-12 Synaptic Pharmaceutical Corporation Oxazolidinones as α1A receptor antagonists
US6316623B1 (en) * 1998-08-21 2001-11-13 Isis Pharmaceuticals, Inc. Ethylenediamine compound libraries
US6951849B2 (en) * 2001-10-02 2005-10-04 Acadia Pharmaceuticals Inc. Benzimidazolidinone derivatives as muscarinic agents
WO2003028650A2 (en) * 2001-10-02 2003-04-10 Acadia Pharmaceuticals, Inc. Benzimidazolidinone derivatives as muscarinic agents
MY148504A (en) * 2005-09-30 2013-04-30 Glaxo Group Ltd Compounds which have activity at m? receptor and their uses in medicine
EP1960389B1 (de) * 2005-09-30 2012-08-15 Glaxo Group Limited Verbindungen mit aktivität am m1-rezeptor und ihre verwendung in der medizin
EP1937670A1 (de) * 2005-09-30 2008-07-02 Glaxo Group Limited Benzimidazolone mit aktivität am m1-rezeptor
JP5265513B2 (ja) 2007-02-19 2013-08-14 株式会社カネカ 光学活性3−アミノピペリジン又はその塩の製造方法
WO2011010579A1 (ja) * 2009-07-21 2011-01-27 住友化学株式会社 光学活性ニペコタミドの製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US459757A (en) * 1891-09-22 Electric-arc lamp
US3196152A (en) * 1965-07-20 Phenyl and alkyleneamino substituted imidazolidinones and salts thereof
US3355457A (en) * 1965-05-21 1967-11-28 American Cyanamid Co Substituted 2-imidazolinones
US3459757A (en) * 1965-10-22 1969-08-05 American Cyanamid Co Imidazolidines
US4011238A (en) * 1972-07-26 1977-03-08 Gruppo Lepetit S.P.A. 2-imidazolidione derivatives
GB9106571D0 (en) * 1991-03-27 1991-05-15 Erba Carlo Spa Derivatives of substituted imidazol-2-one and process for their preparation
US5300515A (en) * 1991-01-31 1994-04-05 Kyorin Pharmaceutical Co., Ltd. Carbamic acid derivatives and method for preparing the same
AU682889B2 (en) * 1993-09-15 1997-10-23 Merck Sharp & Dohme Limited Imidazolone and oxazolone derivatives as dopamine antagonists

Also Published As

Publication number Publication date
US5726188A (en) 1998-03-10
HUT75649A (en) 1997-05-28
EP0719772A1 (de) 1996-07-03
HU9600622D0 (en) 1996-05-28
DE69425266D1 (de) 2000-08-17
HU217668B (hu) 2000-03-28
PT719772E (pt) 2000-11-30
AU7624394A (en) 1995-04-03
AU679259B2 (en) 1997-06-26
ES2149281T3 (es) 2000-11-01
KR100323930B1 (ko) 2004-05-06
CA2172162A1 (en) 1995-03-23
CN1135216A (zh) 1996-11-06
JP3916093B2 (ja) 2007-05-16
CN1041088C (zh) 1998-12-09
CA2172162C (en) 2005-04-19
ATE194611T1 (de) 2000-07-15
WO1995007905A1 (fr) 1995-03-23
EP0719772B1 (de) 2000-07-12
GR3034499T3 (en) 2000-12-29
EP0719772A4 (de) 1996-09-04
DK0719772T3 (da) 2000-11-06
JPH07133273A (ja) 1995-05-23
KR960704878A (ko) 1996-10-09

Similar Documents

Publication Publication Date Title
ES2132284T3 (es) Derivados de carbamato de 2-(piperidin-4-il, piridin-4-il y tetrahidropiridin-4-il)-benzofurano-7, su preparacion y su uso como inhibidores de acetilcolinesterasa.
ATE228132T1 (de) Trifluoromethylpyrroloindolcarbonsäure und dessen esterderivat sowie ein verfahren zu seiner herstellung
NO942452D0 (no) Amid- og ureaderivater med antihyperkolesteremisk aktivitet, deres fremstilling og terapeutiske anvendelser
DE69425266T2 (de) Optisch aktive imidazolidinon-derivate und verfahren zu deren herstellung
AU7624494A (en) Imidazolidinone derivative, acid-addition salt thereof, and remedy for senile dementia
NO941073L (no) Fenylglycinamid av heterocykliske, substituerte fenyleddiksyrederivater
ATE270287T1 (de) 2,3-dihydro-1h-isoindolderivate, verfahren zu ihrer herstellung und ihre verwendung als hemmer der serotoninwiederaufnahme
ATE123493T1 (de) 3-(1h-indazol-3-yl)-4-pyridiname, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel.
EP0647446A4 (de) Neue medizinische verwendung von dihydropyridinderivaten.
ATE180251T1 (de) Indan derivate und verfahren zu deren herstellung
ATE130002T1 (de) 1-(pyridinylalkyl)-1h-indole, -indoline und analoge.
ATE299489T1 (de) Aminderivate und verfahren zu ihrer herstellung
ATE364600T1 (de) Verfahren zur herstellung von indol-derivaten und intermediaten dafür
AU561008B2 (en) N,n,-disubstituted alkenamides and phenylalkenamides and heterocyclic starting compounds
ATE200674T1 (de) Herstellung von beta-lactamverbindungen und zwischenprodukte
ATE170188T1 (de) 2'-desoxy-5-fluoruridin, pharmazeutisch anwendbare salze davon, verfahren zu ihrer herstellung und antitumormedikament
ATE197292T1 (de) Verfahren zur herstellung von 2,4-dioxo-3- azabicyclo(3.1.0)hexanen
TW328088B (en) Imidazolidinone derivative and its acid additional salt, for treatment of senile dementia and the process for preparing them
ATE239707T1 (de) 2-phenylpyridine-derivate und verfahren zu deren herstellung
ATE135682T1 (de) 2-(3-phenylpropyl)hydrazine, verfahren zu ihrer herstellung, zwischenprodukte dafür und ihre verwendung als medikamente
KR970001326A (ko) 2-나프타미드 유도체의 제조 방법 및 2-나프타미드 유도체 제조용 화합물

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee