NO941073L - Fenylglycinamid av heterocykliske, substituerte fenyleddiksyrederivater - Google Patents
Fenylglycinamid av heterocykliske, substituerte fenyleddiksyrederivaterInfo
- Publication number
- NO941073L NO941073L NO941073A NO941073A NO941073L NO 941073 L NO941073 L NO 941073L NO 941073 A NO941073 A NO 941073A NO 941073 A NO941073 A NO 941073A NO 941073 L NO941073 L NO 941073L
- Authority
- NO
- Norway
- Prior art keywords
- carbon atoms
- stands
- branched alkyl
- hydrogen
- straight chain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Fenylglycinaraider av heterocyklisk substituerte fenyleddiksyrederivater, med den generelle formel (I) hvor A står for rettkjedet eller forgrenet alkyl eller alkenyl med opptil 8 karbonatomer, eller for cykloalkyl med 3 til 8 karbonatomer, B står for hydrogen, halogen eller for perfluoralkyl med opptil 5 karbonatomer, D står for en gruppe med formelen -CHo-OR^ eller -CO- R7, E står for hydrogen, halogen, nltro, hydroksy, trifluormetyl, trlfluormetoksy, rettkjedet eller forgrenet alkyl, alkoksy eller alkoksykarbonyl med opptil 6 karbonatomer, cyano eller karboksy, L står for hydrogen eller rettkjedet eller forgrenet alkyl med opptil 4 karbonatomer, R1 står for cykloalkyl med 3 til 8 karbonatomer, eller for rettkjedet eller forgrenet alkyl med opptil 8 karbonatomer, som eventuelt er substituert, R2 står for hydrogen eller for rettkjedet eller forgrenet alkyl med opptil 6 karbonatomer, R3 står for hydrogen, hydroksy, halogen eller for rettkjedet eller forgrenet alkoksy med opptil 6 karbonatomer, R4 og R5 er like eller forskjellige og står for hydrogen, fenyl, pyridyl, cykloalkyl med 3 til 8 karbonatomer, eller for rettkjedet eller forgrenet alkyl med opptil 8 karbonatomer, som eventuelt er substituert, eller R4 og R5 danner sammen med nitrogenatomet en 6-med- lemmers mettet heteroring med opptil 3 heteroatomer fra rekken S, N eller O og deres salter. Det blir også beskrevet fremgangsmåter for fremstilling av disse stoffene samt deres anvendelse som virkestoff i legemidler.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4309968A DE4309968A1 (de) | 1993-03-26 | 1993-03-26 | Phenylglycinamide von heterocyclisch substituierten Phenylessigsäurederivaten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO941073D0 NO941073D0 (no) | 1994-03-24 |
| NO941073L true NO941073L (no) | 1994-09-27 |
Family
ID=6484001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO941073A NO941073L (no) | 1993-03-26 | 1994-03-24 | Fenylglycinamid av heterocykliske, substituerte fenyleddiksyrederivater |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0622358A1 (no) |
| JP (1) | JPH06329637A (no) |
| KR (1) | KR940021532A (no) |
| CN (1) | CN1102645A (no) |
| AU (1) | AU5788694A (no) |
| CA (1) | CA2119669A1 (no) |
| CZ (1) | CZ71094A3 (no) |
| DE (1) | DE4309968A1 (no) |
| FI (1) | FI941380A (no) |
| HU (1) | HUT68514A (no) |
| IL (1) | IL109093A0 (no) |
| NO (1) | NO941073L (no) |
| NZ (1) | NZ260163A (no) |
| SK (1) | SK35094A3 (no) |
| ZA (1) | ZA942119B (no) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996036591A1 (fr) * | 1995-05-19 | 1996-11-21 | Kissei Pharmaceutical Co., Ltd. | Derives de 2-hydroxyphenylalkylamine et inhibiteurs de la reaction de maillard |
| DE19613550A1 (de) * | 1996-04-04 | 1997-10-09 | Bayer Ag | Neue Pyrimido[1,2-a]indole |
| EP0802192A1 (de) * | 1996-04-17 | 1997-10-22 | Bayer Ag | Heterocyclisch-substituierte Phenylglycinolamide mit antiatherosklerotischer Wirkung und Verfahren zu ihrer Herstellung |
| DE19619950A1 (de) | 1996-04-17 | 1997-10-23 | Bayer Ag | Heterocyclisch-substituierte Phenylglycinolamide |
| DE19615265A1 (de) * | 1996-04-18 | 1997-12-04 | Bayer Ag | Neue Pyridazino-, Pyrimido-, Pyrazino- und Triazino-indole |
| EP1013273A1 (en) * | 1998-12-23 | 2000-06-28 | Novartis AG | Use of AT-1 receptor antagonist or AT-2 receptor modulator for treating diseases associated with an increase of AT-1 or AT-2 receptors |
| SI1140071T1 (sl) * | 1998-12-23 | 2007-08-31 | Novartis Ag | Uporaba antagonista at-1 receptorja ali modulatorja at-2 receptorja za zdravljenje bolezni povezanih s poveäśanjem at-1 ali at-2 receptorjev |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4200954A1 (de) * | 1991-04-26 | 1992-10-29 | Bayer Ag | Heterocyclisch substituierte phenylessigsaeurederivate |
| DE4208051A1 (de) * | 1992-03-13 | 1993-09-16 | Bayer Ag | Substituierte phenylessigsaeureamide |
-
1993
- 1993-03-26 DE DE4309968A patent/DE4309968A1/de not_active Withdrawn
-
1994
- 1994-03-14 EP EP94103881A patent/EP0622358A1/de not_active Withdrawn
- 1994-03-17 AU AU57886/94A patent/AU5788694A/en not_active Abandoned
- 1994-03-22 JP JP6073763A patent/JPH06329637A/ja not_active Ceased
- 1994-03-23 NZ NZ260163A patent/NZ260163A/en unknown
- 1994-03-23 IL IL10909394A patent/IL109093A0/xx unknown
- 1994-03-23 CA CA002119669A patent/CA2119669A1/en not_active Abandoned
- 1994-03-24 NO NO941073A patent/NO941073L/no unknown
- 1994-03-24 FI FI941380A patent/FI941380A/fi not_active Application Discontinuation
- 1994-03-25 CZ CZ94710A patent/CZ71094A3/cs unknown
- 1994-03-25 KR KR1019940006036A patent/KR940021532A/ko not_active Application Discontinuation
- 1994-03-25 ZA ZA942119A patent/ZA942119B/xx unknown
- 1994-03-25 HU HU9400865A patent/HUT68514A/hu unknown
- 1994-03-25 SK SK350-94A patent/SK35094A3/sk unknown
- 1994-03-26 CN CN94103443A patent/CN1102645A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI941380A (fi) | 1994-09-27 |
| SK35094A3 (en) | 1995-10-11 |
| KR940021532A (ko) | 1994-10-19 |
| NZ260163A (en) | 1996-02-27 |
| AU5788694A (en) | 1994-09-29 |
| ZA942119B (en) | 1994-11-07 |
| CZ71094A3 (en) | 1994-10-19 |
| FI941380A0 (fi) | 1994-03-24 |
| IL109093A0 (en) | 1994-06-24 |
| EP0622358A1 (de) | 1994-11-02 |
| HUT68514A (en) | 1995-06-28 |
| NO941073D0 (no) | 1994-03-24 |
| HU9400865D0 (en) | 1994-06-28 |
| DE4309968A1 (de) | 1994-09-29 |
| JPH06329637A (ja) | 1994-11-29 |
| CN1102645A (zh) | 1995-05-17 |
| CA2119669A1 (en) | 1994-09-27 |
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