ATE194611T1 - Optisch aktive imidazolidinon-derivate und verfahren zu deren herstellung - Google Patents
Optisch aktive imidazolidinon-derivate und verfahren zu deren herstellungInfo
- Publication number
- ATE194611T1 ATE194611T1 AT94926387T AT94926387T ATE194611T1 AT E194611 T1 ATE194611 T1 AT E194611T1 AT 94926387 T AT94926387 T AT 94926387T AT 94926387 T AT94926387 T AT 94926387T AT E194611 T1 ATE194611 T1 AT E194611T1
- Authority
- AT
- Austria
- Prior art keywords
- optically active
- production
- active imidazolidinone
- same
- imidazolidinone derivatives
- Prior art date
Links
- 150000008624 imidazolidinones Chemical class 0.000 title abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- UQOFGTXDASPNLL-XHNCKOQMSA-N Muscarine Chemical compound C[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O UQOFGTXDASPNLL-XHNCKOQMSA-N 0.000 abstract 1
- 206010039966 Senile dementia Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000001713 cholinergic effect Effects 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- -1 nitro, amino Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25498393 | 1993-09-17 | ||
| JP24226494A JP3916093B2 (ja) | 1993-09-17 | 1994-09-09 | 光学活性イミダゾリジノン誘導体とその製造方法 |
| PCT/JP1994/001505 WO1995007905A1 (en) | 1993-09-17 | 1994-09-12 | Optically active imidazolidinone derivative and process for producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE194611T1 true ATE194611T1 (de) | 2000-07-15 |
Family
ID=26535688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94926387T ATE194611T1 (de) | 1993-09-17 | 1994-09-12 | Optisch aktive imidazolidinon-derivate und verfahren zu deren herstellung |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5726188A (de) |
| EP (1) | EP0719772B1 (de) |
| JP (1) | JP3916093B2 (de) |
| KR (1) | KR100323930B1 (de) |
| CN (1) | CN1041088C (de) |
| AT (1) | ATE194611T1 (de) |
| AU (1) | AU679259B2 (de) |
| CA (1) | CA2172162C (de) |
| DE (1) | DE69425266T2 (de) |
| DK (1) | DK0719772T3 (de) |
| ES (1) | ES2149281T3 (de) |
| GR (1) | GR3034499T3 (de) |
| HU (1) | HU217668B (de) |
| PT (1) | PT719772E (de) |
| WO (1) | WO1995007905A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69407607T2 (de) * | 1993-09-15 | 1998-08-06 | Merck Sharp & Dohme | Imidanolon- und oxanolonderivate als dopaminantagonisten |
| US6159990A (en) | 1997-06-18 | 2000-12-12 | Synaptic Pharmaceutical Corporation | Oxazolidinones as α1A receptor antagonists |
| US6316623B1 (en) * | 1998-08-21 | 2001-11-13 | Isis Pharmaceuticals, Inc. | Ethylenediamine compound libraries |
| CA2457647A1 (en) * | 2001-10-02 | 2003-04-10 | Acadia Pharmaceuticals, Inc. | Benzimidazolidinone derivatives as muscarinic agents |
| US6951849B2 (en) * | 2001-10-02 | 2005-10-04 | Acadia Pharmaceuticals Inc. | Benzimidazolidinone derivatives as muscarinic agents |
| EA016286B1 (ru) * | 2005-09-30 | 2012-03-30 | Глэксо Груп Лимитед | Соединения, которые обладают активностью по отношению к рецепторам м, и их применения в медицине |
| JP5209479B2 (ja) * | 2005-09-30 | 2013-06-12 | グラクソ グループ リミテッド | Ｍ１受容体にて活性を有するベンゾイミダゾロン類 |
| JP5209481B2 (ja) * | 2005-09-30 | 2013-06-12 | グラクソ グループ リミテッド | Ｍ１受容体にて活性を有する化合物および医薬におけるそれらの使用 |
| WO2008102720A1 (ja) | 2007-02-19 | 2008-08-28 | Kaneka Corporation | 光学活性３－アミノピペリジン又はその塩の製造方法 |
| EP2457899A4 (de) * | 2009-07-21 | 2015-06-03 | Sumitomo Chemical Co | Verfahren zur herstellung von optisch aktivem nipecotamid |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3196152A (en) * | 1965-07-20 | Phenyl and alkyleneamino substituted imidazolidinones and salts thereof | ||
| US459757A (en) * | 1891-09-22 | Electric-arc lamp | ||
| US3355457A (en) * | 1965-05-21 | 1967-11-28 | American Cyanamid Co | Substituted 2-imidazolinones |
| US3459757A (en) * | 1965-10-22 | 1969-08-05 | American Cyanamid Co | Imidazolidines |
| US4011238A (en) * | 1972-07-26 | 1977-03-08 | Gruppo Lepetit S.P.A. | 2-imidazolidione derivatives |
| GB9106571D0 (en) * | 1991-03-27 | 1991-05-15 | Erba Carlo Spa | Derivatives of substituted imidazol-2-one and process for their preparation |
| US5300515A (en) * | 1991-01-31 | 1994-04-05 | Kyorin Pharmaceutical Co., Ltd. | Carbamic acid derivatives and method for preparing the same |
| DE69407607T2 (de) * | 1993-09-15 | 1998-08-06 | Merck Sharp & Dohme | Imidanolon- und oxanolonderivate als dopaminantagonisten |
-
1994
- 1994-09-09 JP JP24226494A patent/JP3916093B2/ja not_active Expired - Fee Related
- 1994-09-12 CN CN94194134A patent/CN1041088C/zh not_active Expired - Fee Related
- 1994-09-12 EP EP94926387A patent/EP0719772B1/de not_active Expired - Lifetime
- 1994-09-12 CA CA002172162A patent/CA2172162C/en not_active Expired - Fee Related
- 1994-09-12 HU HU9600622A patent/HU217668B/hu not_active IP Right Cessation
- 1994-09-12 AU AU76243/94A patent/AU679259B2/en not_active Ceased
- 1994-09-12 KR KR1019960701412A patent/KR100323930B1/ko not_active Expired - Fee Related
- 1994-09-12 ES ES94926387T patent/ES2149281T3/es not_active Expired - Lifetime
- 1994-09-12 DK DK94926387T patent/DK0719772T3/da active
- 1994-09-12 PT PT94926387T patent/PT719772E/pt unknown
- 1994-09-12 US US08/612,827 patent/US5726188A/en not_active Expired - Fee Related
- 1994-09-12 AT AT94926387T patent/ATE194611T1/de not_active IP Right Cessation
- 1994-09-12 WO PCT/JP1994/001505 patent/WO1995007905A1/ja not_active Ceased
- 1994-09-12 DE DE69425266T patent/DE69425266T2/de not_active Expired - Fee Related
-
2000
- 2000-09-28 GR GR20000402189T patent/GR3034499T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP3916093B2 (ja) | 2007-05-16 |
| ES2149281T3 (es) | 2000-11-01 |
| DK0719772T3 (da) | 2000-11-06 |
| JPH07133273A (ja) | 1995-05-23 |
| EP0719772A1 (de) | 1996-07-03 |
| DE69425266T2 (de) | 2001-02-22 |
| CA2172162C (en) | 2005-04-19 |
| PT719772E (pt) | 2000-11-30 |
| EP0719772A4 (de) | 1996-09-04 |
| CN1041088C (zh) | 1998-12-09 |
| US5726188A (en) | 1998-03-10 |
| CA2172162A1 (en) | 1995-03-23 |
| HU9600622D0 (en) | 1996-05-28 |
| EP0719772B1 (de) | 2000-07-12 |
| AU679259B2 (en) | 1997-06-26 |
| GR3034499T3 (en) | 2000-12-29 |
| KR960704878A (ko) | 1996-10-09 |
| DE69425266D1 (de) | 2000-08-17 |
| HUT75649A (en) | 1997-05-28 |
| KR100323930B1 (ko) | 2004-05-06 |
| AU7624394A (en) | 1995-04-03 |
| HU217668B (hu) | 2000-03-28 |
| WO1995007905A1 (en) | 1995-03-23 |
| CN1135216A (zh) | 1996-11-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |