ES2149281T3 - Derivado opticamente activo de imidazolidinona y su proceso de fabricacion. - Google Patents
Derivado opticamente activo de imidazolidinona y su proceso de fabricacion.Info
- Publication number
- ES2149281T3 ES2149281T3 ES94926387T ES94926387T ES2149281T3 ES 2149281 T3 ES2149281 T3 ES 2149281T3 ES 94926387 T ES94926387 T ES 94926387T ES 94926387 T ES94926387 T ES 94926387T ES 2149281 T3 ES2149281 T3 ES 2149281T3
- Authority
- ES
- Spain
- Prior art keywords
- optically active
- imidazolidinone
- manufacturing process
- active derivative
- same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
SE PRESENTA UN DERIVADO DE LA IMIDAZOLIDINONA OPTICAMENTE ACTIVO REPRESENTADO POR LA FORMULA GENERAL (I) QUE TIENE ACTIVIDAD COLINERGICA (UNA ACTIVIDAD DE LA MUSCARINA M{SUB,1}) Y QUE ES UTIL PARA EL TRATAMIENTO DE LA DEMENCIA SENIL, UNA SAL FARMACOLOGICAMENTE ACEPTABLE DE ADICION ACIDA DEL MISMO, Y UN PROCESO PARA PRODUCIR EL MISMO, Y EN DONDE R Y R1 PUEDEN SER IGUALES O DIFERENTES Y CADA UNA REPRESENTA HIDROGENO, HALOGENO, ALQUILO INFERIOR OPCIONALMENTE HALOGENADO, ALCOXIDO INFERIOR, ALQUILTIO INFERIOR, ALCOXICARBONILO INFERIOR, NITRO, AMINO O CIANO Y N REPRESENTA 1 A 4.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP25498393 | 1993-09-17 | ||
JP24226494A JP3916093B2 (ja) | 1993-09-17 | 1994-09-09 | 光学活性イミダゾリジノン誘導体とその製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2149281T3 true ES2149281T3 (es) | 2000-11-01 |
Family
ID=26535688
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94926387T Expired - Lifetime ES2149281T3 (es) | 1993-09-17 | 1994-09-12 | Derivado opticamente activo de imidazolidinona y su proceso de fabricacion. |
Country Status (15)
Country | Link |
---|---|
US (1) | US5726188A (es) |
EP (1) | EP0719772B1 (es) |
JP (1) | JP3916093B2 (es) |
KR (1) | KR100323930B1 (es) |
CN (1) | CN1041088C (es) |
AT (1) | ATE194611T1 (es) |
AU (1) | AU679259B2 (es) |
CA (1) | CA2172162C (es) |
DE (1) | DE69425266T2 (es) |
DK (1) | DK0719772T3 (es) |
ES (1) | ES2149281T3 (es) |
GR (1) | GR3034499T3 (es) |
HU (1) | HU217668B (es) |
PT (1) | PT719772E (es) |
WO (1) | WO1995007905A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995007904A1 (en) * | 1993-09-15 | 1995-03-23 | Merck Sharp & Dohme Limited | Imidazolone and oxazolone derivatives as dopamine antagonists |
US6159990A (en) * | 1997-06-18 | 2000-12-12 | Synaptic Pharmaceutical Corporation | Oxazolidinones as α1A receptor antagonists |
US6316623B1 (en) * | 1998-08-21 | 2001-11-13 | Isis Pharmaceuticals, Inc. | Ethylenediamine compound libraries |
US6951849B2 (en) * | 2001-10-02 | 2005-10-04 | Acadia Pharmaceuticals Inc. | Benzimidazolidinone derivatives as muscarinic agents |
EP1432420B1 (en) * | 2001-10-02 | 2011-07-13 | Acadia Pharmaceuticals Inc. | Benzimidazolidinone derivatives as muscarinic agents |
UA101299C2 (uk) * | 2005-09-30 | 2013-03-25 | Глаксо Груп Лімітед | Сполуки, що мають активність стосовно рецепторів м1, та їх застосування в медицині |
US8288412B2 (en) * | 2005-09-30 | 2012-10-16 | Glaxo Group Limited | Compounds which have activity at M1 receptor and their uses in medicine |
US8288413B2 (en) * | 2005-09-30 | 2012-10-16 | Glaxo Group Limited | Benzimidazolones which have activity at M1 receptor |
WO2008102720A1 (ja) * | 2007-02-19 | 2008-08-28 | Kaneka Corporation | 光学活性3-アミノピペリジン又はその塩の製造方法 |
US20120123128A1 (en) * | 2009-07-21 | 2012-05-17 | Sumitomo Chemical Company, Limited | Process for production of optically active nipecotamide |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US459757A (en) * | 1891-09-22 | Electric-arc lamp | ||
US3196152A (en) * | 1965-07-20 | Phenyl and alkyleneamino substituted imidazolidinones and salts thereof | ||
US3355457A (en) * | 1965-05-21 | 1967-11-28 | American Cyanamid Co | Substituted 2-imidazolinones |
US3459757A (en) * | 1965-10-22 | 1969-08-05 | American Cyanamid Co | Imidazolidines |
US4011238A (en) * | 1972-07-26 | 1977-03-08 | Gruppo Lepetit S.P.A. | 2-imidazolidione derivatives |
GB9106571D0 (en) * | 1991-03-27 | 1991-05-15 | Erba Carlo Spa | Derivatives of substituted imidazol-2-one and process for their preparation |
US5300515A (en) * | 1991-01-31 | 1994-04-05 | Kyorin Pharmaceutical Co., Ltd. | Carbamic acid derivatives and method for preparing the same |
WO1995007904A1 (en) * | 1993-09-15 | 1995-03-23 | Merck Sharp & Dohme Limited | Imidazolone and oxazolone derivatives as dopamine antagonists |
-
1994
- 1994-09-09 JP JP24226494A patent/JP3916093B2/ja not_active Expired - Fee Related
- 1994-09-12 AT AT94926387T patent/ATE194611T1/de not_active IP Right Cessation
- 1994-09-12 CN CN94194134A patent/CN1041088C/zh not_active Expired - Fee Related
- 1994-09-12 ES ES94926387T patent/ES2149281T3/es not_active Expired - Lifetime
- 1994-09-12 WO PCT/JP1994/001505 patent/WO1995007905A1/ja active IP Right Grant
- 1994-09-12 DK DK94926387T patent/DK0719772T3/da active
- 1994-09-12 CA CA002172162A patent/CA2172162C/en not_active Expired - Fee Related
- 1994-09-12 HU HU9600622A patent/HU217668B/hu not_active IP Right Cessation
- 1994-09-12 EP EP94926387A patent/EP0719772B1/en not_active Expired - Lifetime
- 1994-09-12 AU AU76243/94A patent/AU679259B2/en not_active Ceased
- 1994-09-12 DE DE69425266T patent/DE69425266T2/de not_active Expired - Fee Related
- 1994-09-12 KR KR1019960701412A patent/KR100323930B1/ko not_active IP Right Cessation
- 1994-09-12 US US08/612,827 patent/US5726188A/en not_active Expired - Fee Related
- 1994-09-12 PT PT94926387T patent/PT719772E/pt unknown
-
2000
- 2000-09-28 GR GR20000402189T patent/GR3034499T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH07133273A (ja) | 1995-05-23 |
CA2172162A1 (en) | 1995-03-23 |
DE69425266D1 (de) | 2000-08-17 |
CA2172162C (en) | 2005-04-19 |
AU679259B2 (en) | 1997-06-26 |
HUT75649A (en) | 1997-05-28 |
JP3916093B2 (ja) | 2007-05-16 |
AU7624394A (en) | 1995-04-03 |
DE69425266T2 (de) | 2001-02-22 |
KR100323930B1 (ko) | 2004-05-06 |
EP0719772A1 (en) | 1996-07-03 |
EP0719772B1 (en) | 2000-07-12 |
US5726188A (en) | 1998-03-10 |
PT719772E (pt) | 2000-11-30 |
GR3034499T3 (en) | 2000-12-29 |
ATE194611T1 (de) | 2000-07-15 |
WO1995007905A1 (fr) | 1995-03-23 |
KR960704878A (ko) | 1996-10-09 |
EP0719772A4 (en) | 1996-09-04 |
CN1041088C (zh) | 1998-12-09 |
CN1135216A (zh) | 1996-11-06 |
DK0719772T3 (da) | 2000-11-06 |
HU217668B (hu) | 2000-03-28 |
HU9600622D0 (en) | 1996-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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