HU181911B - Process for preparing alpha-fluoromethyl-alpha-amino-alkane-carboxylic acids and esters thereof - Google Patents
Process for preparing alpha-fluoromethyl-alpha-amino-alkane-carboxylic acids and esters thereof Download PDFInfo
- Publication number
- HU181911B HU181911B HU78ME2169A HUME002169A HU181911B HU 181911 B HU181911 B HU 181911B HU 78ME2169 A HU78ME2169 A HU 78ME2169A HU ME002169 A HUME002169 A HU ME002169A HU 181911 B HU181911 B HU 181911B
- Authority
- HU
- Hungary
- Prior art keywords
- formula
- compound
- fluoromethyl
- optically active
- acid addition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80238977A | 1977-06-01 | 1977-06-01 | |
| US05/802,391 US4325961A (en) | 1977-06-01 | 1977-06-01 | Fluorinated amino acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU181911B true HU181911B (en) | 1983-11-28 |
Family
ID=27122442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU78ME2169A HU181911B (en) | 1977-06-01 | 1978-05-30 | Process for preparing alpha-fluoromethyl-alpha-amino-alkane-carboxylic acids and esters thereof |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS5416423A (es) |
| AR (1) | AR223463A1 (es) |
| AT (1) | AT360509B (es) |
| AU (1) | AU518479B2 (es) |
| CA (1) | CA1120040A (es) |
| CH (1) | CH639639A5 (es) |
| DD (1) | DD138651A5 (es) |
| DE (1) | DE2824116A1 (es) |
| DK (1) | DK149841C (es) |
| ES (1) | ES470296A1 (es) |
| FI (1) | FI66840C (es) |
| FR (1) | FR2392958A1 (es) |
| GB (1) | GB1602525A (es) |
| GR (1) | GR64495B (es) |
| HK (1) | HK18184A (es) |
| HU (1) | HU181911B (es) |
| IE (1) | IE46983B1 (es) |
| IT (1) | IT1104709B (es) |
| LU (1) | LU79750A1 (es) |
| NL (1) | NL190485C (es) |
| NO (1) | NO147382C (es) |
| NZ (1) | NZ187377A (es) |
| PL (1) | PL115731B1 (es) |
| PT (1) | PT68102B (es) |
| SE (1) | SE7806440L (es) |
| YU (1) | YU129178A (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1091661A (en) * | 1977-07-11 | 1980-12-16 | Philippe Bey | .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS |
| IL59481A0 (en) * | 1977-07-11 | 1980-05-30 | Merrell Toraude & Co | -halomethyl amino acids |
| ZA783273B (en) * | 1977-07-11 | 1979-06-27 | Merrell Toraude & Co | A-halomethyl amino acids |
| US4315095A (en) * | 1977-07-28 | 1982-02-09 | Merrell Toraude Et Compagnie | α-Halomethyl derivatives of amino acids |
| ATE3282T1 (de) * | 1978-07-24 | 1983-05-15 | Merck & Co. Inc. | Alpha-difluormethyl-alpha-aminosaeuren und sie enthaltende pharmazeutische zusammensetzung. |
| IE49522B1 (en) * | 1979-04-26 | 1985-10-16 | Merrell Toraude & Co | Alpha-halomethylaminoacids |
| NZ194347A (en) * | 1979-07-26 | 1982-11-23 | Merrell Toraude & Co | Fluorinated alkenylamines intermediate alkenyl fluorinated methyl ketimine magnesium halides and preparation of certain amino alkanoic acids |
| ZA813018B (en) * | 1980-05-09 | 1982-05-26 | Merrell Toraude & Co | Fluoromethylated tyrosine methyl ester |
| NZ197394A (en) * | 1980-06-16 | 1984-09-28 | Merrell Dow Pharma | Inhibition of protozoal growth in animals with certain-substituted-amines or amino acids |
| US4421767A (en) * | 1981-06-01 | 1983-12-20 | Merrell Toraude Et Compagnie | Compounds and methods for treating depression |
| GB9325368D0 (en) * | 1993-12-10 | 1994-02-16 | Univ Bristol | Organic compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3046300A (en) * | 1960-10-21 | 1962-07-24 | Merck & Co Inc | alpha-trifluoromethyloxyphenylalanines |
-
1978
- 1978-05-25 NZ NZ187377A patent/NZ187377A/xx unknown
- 1978-05-25 FR FR7815567A patent/FR2392958A1/fr active Granted
- 1978-05-25 GR GR56328A patent/GR64495B/el unknown
- 1978-05-26 FI FI781674A patent/FI66840C/fi not_active IP Right Cessation
- 1978-05-26 AR AR272336A patent/AR223463A1/es active
- 1978-05-29 AU AU36586/78A patent/AU518479B2/en not_active Expired
- 1978-05-29 CA CA000304318A patent/CA1120040A/en not_active Expired
- 1978-05-29 ES ES470296A patent/ES470296A1/es not_active Expired
- 1978-05-30 YU YU01291/78A patent/YU129178A/xx unknown
- 1978-05-30 PT PT68102A patent/PT68102B/pt unknown
- 1978-05-30 HU HU78ME2169A patent/HU181911B/hu unknown
- 1978-05-30 GB GB24330/78A patent/GB1602525A/en not_active Expired
- 1978-05-30 DD DD78205669A patent/DD138651A5/xx unknown
- 1978-05-30 IE IE1078/78A patent/IE46983B1/en unknown
- 1978-05-30 AT AT393278A patent/AT360509B/de not_active IP Right Cessation
- 1978-05-30 DK DK237978A patent/DK149841C/da not_active IP Right Cessation
- 1978-05-31 NO NO781892A patent/NO147382C/no unknown
- 1978-05-31 PL PL1978207242A patent/PL115731B1/pl unknown
- 1978-05-31 CH CH597978A patent/CH639639A5/de not_active IP Right Cessation
- 1978-05-31 IT IT49637/78A patent/IT1104709B/it active
- 1978-06-01 DE DE19782824116 patent/DE2824116A1/de active Granted
- 1978-06-01 LU LU79750A patent/LU79750A1/xx unknown
- 1978-06-01 JP JP6501678A patent/JPS5416423A/ja active Granted
- 1978-06-01 NL NLAANVRAGE7805981,A patent/NL190485C/xx not_active IP Right Cessation
- 1978-06-01 SE SE7806440A patent/SE7806440L/xx unknown
-
1984
- 1984-03-01 HK HK181/84A patent/HK18184A/xx not_active IP Right Cessation
Also Published As
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