ATE3282T1 - Alpha-difluormethyl-alpha-aminosaeuren und sie enthaltende pharmazeutische zusammensetzung. - Google Patents
Alpha-difluormethyl-alpha-aminosaeuren und sie enthaltende pharmazeutische zusammensetzung.Info
- Publication number
- ATE3282T1 ATE3282T1 AT79102581T AT79102581T ATE3282T1 AT E3282 T1 ATE3282 T1 AT E3282T1 AT 79102581 T AT79102581 T AT 79102581T AT 79102581 T AT79102581 T AT 79102581T AT E3282 T1 ATE3282 T1 AT E3282T1
- Authority
- AT
- Austria
- Prior art keywords
- alpha
- difluoromethyl
- amino acids
- pharmaceutical composition
- composition containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 235000002374 tyrosine Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
- C07D233/78—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/48—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation involving decarboxylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
- C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92721078A | 1978-07-24 | 1978-07-24 | |
| EP79102581A EP0007600B1 (de) | 1978-07-24 | 1979-07-23 | Alpha-Difluormethyl-alpha-aminosäuren und sie enthaltende pharmazeutische Zusammensetzung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE3282T1 true ATE3282T1 (de) | 1983-05-15 |
Family
ID=25454398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT79102581T ATE3282T1 (de) | 1978-07-24 | 1979-07-23 | Alpha-difluormethyl-alpha-aminosaeuren und sie enthaltende pharmazeutische zusammensetzung. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0007600B1 (de) |
| JP (1) | JPS5519282A (de) |
| AT (1) | ATE3282T1 (de) |
| DE (1) | DE2965364D1 (de) |
| DK (1) | DK309479A (de) |
| IE (1) | IE49729B1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE49522B1 (en) * | 1979-04-26 | 1985-10-16 | Merrell Toraude & Co | Alpha-halomethylaminoacids |
| ZA813018B (en) * | 1980-05-09 | 1982-05-26 | Merrell Toraude & Co | Fluoromethylated tyrosine methyl ester |
| US4421767A (en) * | 1981-06-01 | 1983-12-20 | Merrell Toraude Et Compagnie | Compounds and methods for treating depression |
| EP0451422A1 (de) * | 1990-04-13 | 1991-10-16 | Merrell Dow Pharmaceuticals Inc. | Pharmazeutisch aktive Fluoromethyltyrosin-Verbindungen |
| KR20210112319A (ko) * | 2018-12-06 | 2021-09-14 | 센다 바이오사이언시즈, 인크. | 파킨슨병을 치료하기 위한 데카르복실라제 억제제 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3046300A (en) * | 1960-10-21 | 1962-07-24 | Merck & Co Inc | alpha-trifluoromethyloxyphenylalanines |
| GR64495B (en) * | 1977-06-01 | 1980-03-31 | Merck & Co Inc | Novel fluorinated amino acids |
| ZA783273B (en) * | 1977-07-11 | 1979-06-27 | Merrell Toraude & Co | A-halomethyl amino acids |
-
1979
- 1979-07-23 AT AT79102581T patent/ATE3282T1/de not_active IP Right Cessation
- 1979-07-23 DE DE7979102581T patent/DE2965364D1/de not_active Expired
- 1979-07-23 EP EP79102581A patent/EP0007600B1/de not_active Expired
- 1979-07-23 DK DK309479A patent/DK309479A/da not_active Application Discontinuation
- 1979-07-24 JP JP9334679A patent/JPS5519282A/ja active Pending
- 1979-08-08 IE IE1378/79A patent/IE49729B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE49729B1 (en) | 1985-12-11 |
| DE2965364D1 (en) | 1983-06-16 |
| DK309479A (da) | 1980-02-19 |
| EP0007600B1 (de) | 1983-05-11 |
| JPS5519282A (en) | 1980-02-09 |
| IE791378L (en) | 1980-01-24 |
| EP0007600A1 (de) | 1980-02-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |