DD138651A5 - Verfahren zur herstellung von alpha-fluormethyl-alpha-amino-alkansaeuren - Google Patents

Verfahren zur herstellung von alpha-fluormethyl-alpha-amino-alkansaeuren

Info

Publication number
DD138651A5
DD138651A5 DD78205669A DD20566978A DD138651A5 DD 138651 A5 DD138651 A5 DD 138651A5 DD 78205669 A DD78205669 A DD 78205669A DD 20566978 A DD20566978 A DD 20566978A DD 138651 A5 DD138651 A5 DD 138651A5
Authority
DD
German Democratic Republic
Prior art keywords
alpha
alkansaures
fluoromethyl
amino
preparing
Prior art date
Application number
DD78205669A
Other languages
German (de)
English (en)
Inventor
Janos Kollonitsch
Arthur A Patchett
Stephen Marburg
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/802,391 external-priority patent/US4325961A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DD138651A5 publication Critical patent/DD138651A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
DD78205669A 1977-06-01 1978-05-30 Verfahren zur herstellung von alpha-fluormethyl-alpha-amino-alkansaeuren DD138651A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80238977A 1977-06-01 1977-06-01
US05/802,391 US4325961A (en) 1977-06-01 1977-06-01 Fluorinated amino acids

Publications (1)

Publication Number Publication Date
DD138651A5 true DD138651A5 (de) 1979-11-14

Family

ID=27122442

Family Applications (1)

Application Number Title Priority Date Filing Date
DD78205669A DD138651A5 (de) 1977-06-01 1978-05-30 Verfahren zur herstellung von alpha-fluormethyl-alpha-amino-alkansaeuren

Country Status (26)

Country Link
JP (1) JPS5416423A (xx)
AR (1) AR223463A1 (xx)
AT (1) AT360509B (xx)
AU (1) AU518479B2 (xx)
CA (1) CA1120040A (xx)
CH (1) CH639639A5 (xx)
DD (1) DD138651A5 (xx)
DE (1) DE2824116A1 (xx)
DK (1) DK149841C (xx)
ES (1) ES470296A1 (xx)
FI (1) FI66840C (xx)
FR (1) FR2392958A1 (xx)
GB (1) GB1602525A (xx)
GR (1) GR64495B (xx)
HK (1) HK18184A (xx)
HU (1) HU181911B (xx)
IE (1) IE46983B1 (xx)
IT (1) IT1104709B (xx)
LU (1) LU79750A1 (xx)
NL (1) NL190485C (xx)
NO (1) NO147382C (xx)
NZ (1) NZ187377A (xx)
PL (1) PL115731B1 (xx)
PT (1) PT68102B (xx)
SE (1) SE7806440L (xx)
YU (1) YU129178A (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
IL59481A0 (en) * 1977-07-11 1980-05-30 Merrell Toraude & Co -halomethyl amino acids
ZA783273B (en) * 1977-07-11 1979-06-27 Merrell Toraude & Co A-halomethyl amino acids
US4315095A (en) * 1977-07-28 1982-02-09 Merrell Toraude Et Compagnie α-Halomethyl derivatives of amino acids
ATE3282T1 (de) * 1978-07-24 1983-05-15 Merck & Co. Inc. Alpha-difluormethyl-alpha-aminosaeuren und sie enthaltende pharmazeutische zusammensetzung.
IE49522B1 (en) * 1979-04-26 1985-10-16 Merrell Toraude & Co Alpha-halomethylaminoacids
NZ194347A (en) * 1979-07-26 1982-11-23 Merrell Toraude & Co Fluorinated alkenylamines intermediate alkenyl fluorinated methyl ketimine magnesium halides and preparation of certain amino alkanoic acids
ZA813018B (en) * 1980-05-09 1982-05-26 Merrell Toraude & Co Fluoromethylated tyrosine methyl ester
NZ197394A (en) * 1980-06-16 1984-09-28 Merrell Dow Pharma Inhibition of protozoal growth in animals with certain-substituted-amines or amino acids
US4421767A (en) * 1981-06-01 1983-12-20 Merrell Toraude Et Compagnie Compounds and methods for treating depression
GB9325368D0 (en) * 1993-12-10 1994-02-16 Univ Bristol Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines

Also Published As

Publication number Publication date
NL190485C (nl) 1994-03-16
DE2824116C2 (xx) 1989-04-27
HU181911B (en) 1983-11-28
CA1120040A (en) 1982-03-16
JPS641474B2 (xx) 1989-01-11
PL207242A1 (pl) 1979-04-23
NL190485B (nl) 1993-10-18
FI66840B (fi) 1984-08-31
PL115731B1 (en) 1981-04-30
AU518479B2 (en) 1981-10-01
IT7849637A0 (it) 1978-05-31
IE46983B1 (en) 1983-11-16
NO147382C (no) 1983-03-30
DE2824116A1 (de) 1978-12-14
FR2392958B1 (xx) 1980-10-24
PT68102A (en) 1978-06-01
IE781078L (en) 1978-12-01
NO147382B (no) 1982-12-20
IT1104709B (it) 1985-10-28
YU129178A (en) 1983-01-21
HK18184A (en) 1984-03-09
FR2392958A1 (fr) 1978-12-29
FI781674A (fi) 1978-12-02
NL7805981A (nl) 1978-12-05
GB1602525A (en) 1981-11-11
CH639639A5 (en) 1983-11-30
LU79750A1 (fr) 1979-02-02
ES470296A1 (es) 1979-09-16
SE7806440L (sv) 1978-12-02
AR223463A1 (es) 1981-08-31
ATA393278A (de) 1980-06-15
DK149841C (da) 1987-04-21
JPS5416423A (en) 1979-02-07
NO781892L (no) 1978-12-04
DK149841B (da) 1986-10-13
PT68102B (en) 1982-06-08
DK237978A (da) 1979-01-19
GR64495B (en) 1980-03-31
AT360509B (de) 1981-01-12
AU3658678A (en) 1979-12-06
FI66840C (fi) 1984-12-10
NZ187377A (en) 1981-05-15

Similar Documents

Publication Publication Date Title
DD137107A5 (de) Verfahren zur herstellung von spiro-hydantoinderivaten
DD135380A5 (de) Verfahren zur herstellung von 4-acylamino-phenyl-aethanolaminen
DD129103A5 (de) Verfahren zur herstellung von n-phosphonomethylglycin
DD135500A5 (de) Verfahren zur herstellung von polyaetheramid-saeuren
DD131931A5 (de) Verfahren zur herstellung von spiro-hydantoin-verbindungen
DD136616A5 (de) Verfahren zur herstellung von 1,4:3,6-dianhydro-d-glucit-2-nitrat
DD139256A5 (de) Verfahren zur herstellung von substituierten diaminoanthrachinonen
DD135482A5 (de) Verfahren zur herstellung von p-benzochinon
DD131858A5 (de) Verfahren zur herstellung von 3-chlorcephemverbindungen
DD138651A5 (de) Verfahren zur herstellung von alpha-fluormethyl-alpha-amino-alkansaeuren
DD137098A5 (de) Verfahren zur herstellung von cyclobutanonen
DD137584A5 (de) Verfahren zur herstellung von 4-hydroxy-2-benzimidazolinon-derivaten
DD135383A5 (de) Verfahren zur herstellung von 1-azolyl-3,3-dimethyl-1-phenoxy-butan-2-onen
ATA392577A (de) Verfahren zur herstellung von acylcyaniden
DD131556A5 (de) Verfahren zur herstellung von 5-m-tolyoxyuracil
DD134089A5 (de) Verfahren zur herstellung von 4-diphenylmethylen-1-hydroxybenzylpiperidinen
DD137926A5 (de) Verfahren zur herstellung von n-substituierten alpha-ketocarbonsaeureamiden
DD136745A5 (de) Verfahren zur herstellung von auranofin
ATA392477A (de) Verfahren zur herstellung von acylcyaniden
DD138202A5 (de) Verfahren zur herstellung von veraetherten cycloalkanolen
DD132431A5 (de) Verfahren zur herstellung von aryloxy-1-amino-3-propanolen-2
DD131013A5 (de) Verfahren zur herstellung von alpha-ketocarbonsaeuren(b)
DD134517A5 (de) Verfahren zur herstellung von p-nitroso-diphenylhydroxylaminen
DD134524A5 (de) Verfahren zur herstellung von 1-oxadethiacephamverbindungen
DD131088A5 (de) Verfahren zur herstellung von diaminoalkoxybenzolen