HRP970711B1 - Steroids substituted in position 11, method of preparation, application as medicines and pharmaceutical compositions containing them - Google Patents

Steroids substituted in position 11, method of preparation, application as medicines and pharmaceutical compositions containing them

Info

Publication number
HRP970711B1
HRP970711B1 HR970711A HRP970711A HRP970711B1 HR P970711 B1 HRP970711 B1 HR P970711B1 HR 970711 A HR970711 A HR 970711A HR P970711 A HRP970711 A HR P970711A HR P970711 B1 HRP970711 B1 HR P970711B1
Authority
HR
Croatia
Prior art keywords
medicines
preparation
application
pharmaceutical compositions
compositions containing
Prior art date
Application number
HR970711A
Other languages
English (en)
Inventor
Yamina Bouali
Francois Nique
Jean-Georges Teutsch
Patrick Van De Velde
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of HRP970711A2 publication Critical patent/HRP970711A2/xx
Publication of HRP970711B1 publication Critical patent/HRP970711B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HR970711A 1996-12-23 1997-12-23 Steroids substituted in position 11, method of preparation, application as medicines and pharmaceutical compositions containing them HRP970711B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9615829A FR2757519B1 (fr) 1996-12-23 1996-12-23 Steroides substitues en position 11, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant

Publications (2)

Publication Number Publication Date
HRP970711A2 HRP970711A2 (en) 1998-10-31
HRP970711B1 true HRP970711B1 (en) 2002-04-30

Family

ID=9498983

Family Applications (1)

Application Number Title Priority Date Filing Date
HR970711A HRP970711B1 (en) 1996-12-23 1997-12-23 Steroids substituted in position 11, method of preparation, application as medicines and pharmaceutical compositions containing them

Country Status (33)

Country Link
US (3) US6207657B1 (ja)
EP (1) EP0946585B1 (ja)
JP (1) JP4376319B2 (ja)
KR (1) KR20000062288A (ja)
CN (1) CN1247541A (ja)
AP (1) AP9901567A0 (ja)
AR (1) AR010857A1 (ja)
AT (1) ATE216396T1 (ja)
AU (1) AU726350B2 (ja)
BR (1) BR9714433A (ja)
CA (1) CA2275955A1 (ja)
CZ (1) CZ227899A3 (ja)
DE (1) DE69712095T2 (ja)
DK (1) DK0946585T3 (ja)
EA (1) EA001868B1 (ja)
ES (1) ES2174329T3 (ja)
FR (1) FR2757519B1 (ja)
HR (1) HRP970711B1 (ja)
HU (1) HUP0001447A3 (ja)
ID (1) ID22627A (ja)
IL (1) IL130509A0 (ja)
NO (1) NO313333B1 (ja)
NZ (1) NZ336224A (ja)
PL (1) PL334124A1 (ja)
PT (1) PT946585E (ja)
SI (1) SI0946585T1 (ja)
SK (1) SK83099A3 (ja)
TR (1) TR199901453T2 (ja)
TW (1) TW492974B (ja)
UA (1) UA54483C2 (ja)
WO (1) WO1998028324A1 (ja)
YU (1) YU29299A (ja)
ZA (1) ZA9711324B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757519B1 (fr) * 1996-12-23 1999-06-11 Hoechst Marion Roussel Inc Steroides substitues en position 11, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant
FR2780060B1 (fr) * 1998-06-23 2000-08-04 Hoechst Marion Roussel Inc Nouveaux 19-nor steroides 17-halogenes, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant
DE19929715A1 (de) 1999-06-24 2000-12-28 Schering Ag 11ß-langkettig-substituierte Estratriene, Verfahren zur Herstellung , pharmazeutische Präparate, die diese 11ß-langkettig-substituierten Estratriene enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln
FR2826004B1 (fr) * 2001-06-13 2008-03-28 Aventis Pharma Sa Procede de preparation de derives estrogenes
FR2854402B1 (fr) * 2003-04-29 2008-07-04 Aventis Pharma Sa Nouveau procede et intermediaires de preparation de composes 19-nor-steroides

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2640977A2 (en) * 1982-06-11 1990-06-29 Roussel Uclaf New position-11 substituted 19-norsteroids and their application as medicinal products.
US4859585A (en) * 1986-04-17 1989-08-22 Trustees Of Tufts College In-vitro methods for identifying compositions which are agonists and antagonists of estrogens
FR2643638B1 (fr) * 1989-02-24 1991-06-14 Roussel Uclaf Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
JP3377856B2 (ja) * 1993-03-25 2003-02-17 イスクラ産業株式会社 骨吸収抑制・骨形成促進化合物
DE4329867C1 (de) * 1993-09-03 1994-09-15 Siemens Ag Stromspiegel
FR2757519B1 (fr) * 1996-12-23 1999-06-11 Hoechst Marion Roussel Inc Steroides substitues en position 11, leur procede de preparation, leur application comme medicament et les compositions pharmaceutiques les renfermant
FR2757399B1 (fr) * 1996-12-23 1999-12-17 Hoechst Marion Roussel Inc Application de composes steroides substitues en 11 pour la fabrication de medicaments ayant une activite estrogene dissociee
FR2761992B1 (fr) * 1997-04-09 1999-06-11 Hoechst Marion Roussel Inc Nouveaux steroides 4-halogenes, leur procede et intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
FR2771096B1 (fr) * 1997-11-17 2000-08-11 Hoechst Marion Roussel Inc Nouveaux 19-nor steroides, substitues en position 11beta, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
TW492974B (en) 2002-07-01
US6207657B1 (en) 2001-03-27
NO993125D0 (no) 1999-06-23
BR9714433A (pt) 2000-05-02
JP2001507010A (ja) 2001-05-29
AU5667898A (en) 1998-07-17
PL334124A1 (en) 2000-02-14
HRP970711A2 (en) 1998-10-31
KR20000062288A (ko) 2000-10-25
AR010857A1 (es) 2000-07-12
FR2757519A1 (fr) 1998-06-26
DE69712095D1 (de) 2002-05-23
FR2757519B1 (fr) 1999-06-11
PT946585E (pt) 2002-09-30
CA2275955A1 (fr) 1998-07-02
EP0946585B1 (fr) 2002-04-17
EA001868B1 (ru) 2001-10-22
CZ227899A3 (cs) 1999-09-15
EP0946585A1 (fr) 1999-10-06
DK0946585T3 (da) 2002-08-05
YU29299A (sh) 2001-05-28
ES2174329T3 (es) 2002-11-01
DE69712095T2 (de) 2002-11-14
IL130509A0 (en) 2000-06-01
NO993125L (no) 1999-08-20
NO313333B1 (no) 2002-09-16
JP4376319B2 (ja) 2009-12-02
US20020198374A1 (en) 2002-12-26
HUP0001447A3 (en) 2001-03-28
WO1998028324A1 (fr) 1998-07-02
ID22627A (id) 1999-12-02
CN1247541A (zh) 2000-03-15
US6482813B1 (en) 2002-11-19
SK83099A3 (en) 2000-01-18
NZ336224A (en) 2001-02-23
ATE216396T1 (de) 2002-05-15
SI0946585T1 (en) 2002-10-31
US6541464B2 (en) 2003-04-01
AP9901567A0 (en) 1999-06-30
HUP0001447A1 (hu) 2000-11-28
UA54483C2 (uk) 2003-03-17
ZA9711324B (en) 1999-01-19
EA199900588A1 (ru) 2000-02-28
TR199901453T2 (xx) 1999-08-23
AU726350B2 (en) 2000-11-02

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20021105

Year of fee payment: 6

PNAN Change of the applicant name, address/residence

Owner name: AVENTIS PHARMA S.A., FR

PBON Lapse due to non-payment of renewal fee

Effective date: 20031224