HRP960558B1 - New crystalline modifications of cdch, processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents

New crystalline modifications of cdch, processes for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
HRP960558B1
HRP960558B1 HR960558A HRP960558A HRP960558B1 HR P960558 B1 HRP960558 B1 HR P960558B1 HR 960558 A HR960558 A HR 960558A HR P960558 A HRP960558 A HR P960558A HR P960558 B1 HRP960558 B1 HR P960558B1
Authority
HR
Croatia
Prior art keywords
cdch
processes
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
HR960558A
Other languages
English (en)
Inventor
Alfons Grunenberg
Patrick Bosche
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7779831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP960558(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of HRP960558A2 publication Critical patent/HRP960558A2/hr
Publication of HRP960558B1 publication Critical patent/HRP960558B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HR960558A 1995-12-12 1996-11-25 New crystalline modifications of cdch, processes for the preparation thereof and pharmaceutical compositions containing them HRP960558B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19546249A DE19546249A1 (de) 1995-12-12 1995-12-12 Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (2)

Publication Number Publication Date
HRP960558A2 HRP960558A2 (en) 1998-02-28
HRP960558B1 true HRP960558B1 (en) 2002-04-30

Family

ID=7779831

Family Applications (1)

Application Number Title Priority Date Filing Date
HR960558A HRP960558B1 (en) 1995-12-12 1996-11-25 New crystalline modifications of cdch, processes for the preparation thereof and pharmaceutical compositions containing them

Country Status (42)

Country Link
US (1) US5849752A (sh)
EP (1) EP0780390B1 (sh)
JP (1) JP4104687B2 (sh)
KR (1) KR100525146B1 (sh)
CN (1) CN1061348C (sh)
AR (1) AR005009A1 (sh)
AT (1) ATE221531T1 (sh)
AU (1) AU708006B2 (sh)
BG (1) BG62258B1 (sh)
BR (1) BR9605968A (sh)
CA (1) CA2192418C (sh)
CO (1) CO4480105A1 (sh)
CU (1) CU22774A3 (sh)
CZ (1) CZ288657B6 (sh)
DE (2) DE19546249A1 (sh)
DK (1) DK0780390T3 (sh)
EE (1) EE03474B1 (sh)
ES (1) ES2179910T3 (sh)
HR (1) HRP960558B1 (sh)
HU (1) HU226521B1 (sh)
ID (1) ID22625A (sh)
IL (1) IL119795A (sh)
IN (1) IN185805B (sh)
MA (1) MA24342A1 (sh)
MY (1) MY117492A (sh)
NL (1) NL300109I1 (sh)
NO (1) NO306725B1 (sh)
NZ (1) NZ299905A (sh)
PL (1) PL184885B1 (sh)
PT (1) PT780390E (sh)
RO (1) RO119782B1 (sh)
RU (1) RU2162468C2 (sh)
SA (1) SA96170492B1 (sh)
SG (1) SG47201A1 (sh)
SI (1) SI0780390T1 (sh)
SK (1) SK282805B6 (sh)
SV (1) SV1996000109A (sh)
TR (1) TR199600970A2 (sh)
TW (1) TW411340B (sh)
UA (1) UA35638C2 (sh)
YU (1) YU49485B (sh)
ZA (1) ZA9610405B (sh)

Families Citing this family (36)

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US6270799B1 (en) * 1997-09-25 2001-08-07 Bayer Aktiengesellscahft Medicament formulation with a controlled release of an active agent
DE19751948A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6610327B1 (en) * 1998-11-10 2003-08-26 Bayer Aktiengesellschaft Pharmaceutical moxifloxacin preparation
DE19854355A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854356A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854357A1 (de) * 1998-11-25 2000-05-31 Bayer Ag Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908449A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
EP1562942A1 (en) * 2002-10-31 2005-08-17 Ranbaxy Laboratories, Ltd. Amorphous moxifloxacin hydrochloride
ES2332367T5 (es) 2003-04-09 2013-12-17 Dr. Reddy's Laboratories Ltd. Forma cristalina III de clorhidrato de moxifloxacina anhidro y su procedimiento de preparación
EP1651630A1 (en) * 2003-08-05 2006-05-03 Matrix Laboratories Ltd An improved process for the preparation of moxifloxacin hydrochloride
ES2319125T3 (es) * 2003-11-20 2009-05-04 Chemi S.P.A. Polimorfos del clorhidrato del acido 1-ciclopropil-7-((s,s)-2,8-diazadiciclo(4.3.0)-non-8-il)-6-fluoro-1,4-dihidro-8-metoxi-4-oxo-3-quinolina carboxilico y metodos para la preparacion de los mismos.
ITMI20032259A1 (it) 2003-11-20 2005-05-21 Chemi Spa Nuovo polimorfo dell'acido 1-ciclopropil-7-(s,s-2,8-diazabciclo-4.3.0-non-8-il)-6-fluoro-1,4-diidro-8-metossi-4-oxo-chinolin carbossilico cloridrato e metodi per la sua preparazione
US7491725B2 (en) 2004-02-06 2009-02-17 Bristol-Myers Squibb Company Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
DE102004063347A1 (de) * 2004-12-23 2006-07-13 Stada Arzneimittel Ag Gebrauchsfertige Gemcitabinlösungen und Gemcitabinlösungskonzentrate
WO2007033515A1 (fr) * 2005-09-21 2007-03-29 Shenzhen Tys R & D Co., Ltd. Formulation orale contenant de la moxifloxacine et son procédé de préparation
GB0612422D0 (en) * 2006-06-23 2006-08-02 Generics Uk Ltd Novel hydrate form
WO2008000418A2 (en) 2006-06-27 2008-01-03 Sandoz Ag New method for salt preparation
ES2303768B1 (es) * 2006-09-08 2009-06-05 Quimica Sintetica, S.A. Nueva forma cristalina de moxifloxacino clorhidrato.
AU2007320997B2 (en) * 2006-11-13 2012-11-08 Cipla Limited Process for the synthesis of moxifloxacin hydrochloride
EP1992626A1 (en) * 2007-05-10 2008-11-19 Sandoz AG Process for the preparation of moxifloxacin hydrochloride
EP2083010A1 (en) * 2008-01-08 2009-07-29 Chemo Ibérica, S.A. Polymorphic Forms of Moxifloxacin hydrochloride and processes for preparation thereof
EP2154137A1 (en) 2008-08-04 2010-02-17 Chemo Ibérica, S.A. Crystalline form of moxifloxacin base
EP2349220B1 (en) * 2008-10-09 2012-07-25 Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi Using of organic solvents in wet granulation of moxifloxacin
WO2010052726A1 (en) * 2008-11-06 2010-05-14 Hetero Research Foundation Novel polymorph of moxifloxacin hydrochloride
EP2364141B2 (de) 2008-12-08 2017-08-02 ratiopharm GmbH Kompaktiertes moxifloxacin
MX2011012134A (es) 2009-05-15 2012-02-08 Redx Pharma Ltd Derivados de farmaco de oxido-reduccion.
WO2011121596A2 (en) * 2010-04-01 2011-10-06 Neuland Laboratories Ltd. Crystal modification of moxifloxacin hydrochloride
BRPI1106900A2 (pt) 2011-12-26 2013-11-05 Ems Sa Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção
FR2992218B1 (fr) 2012-06-22 2015-01-23 Rivopharm Sa Composition pharmaceutique de chlorhydrate de moxifloxacine et procede de preparation
CN102924449B (zh) * 2012-10-30 2015-08-12 重庆福安药业集团庆余堂制药有限公司 盐酸莫西沙星h晶型及其制备方法和药物组合物
EP2928892B1 (en) 2012-12-04 2018-03-21 Mankind Pharma Ltd. An improved process for the preparation of moxifloxacin hydrochloride
RU2561037C2 (ru) * 2013-02-07 2015-08-20 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Антибактериальная фармацевтическая композиция и способ ее получения
TWI641372B (zh) 2013-03-15 2018-11-21 美商梅琳塔有限責任公司 使用抗生素治療超重和肥胖患者感染的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate
FI871419A (fi) * 1986-03-31 1987-10-01 Sankyo Co Kinolin-3-karboxylsyraderivat, deras framstaellning och anvaendning.
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
DE3910663A1 (de) * 1989-04-03 1990-10-04 Bayer Ag 5-alkylchinoloncarbonsaeuren
TW209865B (sh) 1992-01-10 1993-07-21 Bayer Ag
WO1993015070A1 (en) * 1992-01-31 1993-08-05 Chugai Seiyaku Kabushiki Kaisha Crystal of quinolonecarboxylic acid derivative hydrate
DE4234078A1 (de) 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
JP3268098B2 (ja) * 1992-12-25 2002-03-25 第一製薬株式会社 二環性環状アミン誘導体
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
DK0676199T3 (da) * 1994-04-07 1999-02-08 Pfizer Anvendelse af trovafloxacin eller derivater deraf til fremstilling af et medikament til behandling af H. pylori-infektione

Also Published As

Publication number Publication date
RU2162468C2 (ru) 2001-01-27
ES2179910T3 (es) 2003-02-01
NZ299905A (en) 1998-09-24
CA2192418A1 (en) 1997-06-13
CN1061348C (zh) 2001-01-31
SV1996000109A (es) 1997-10-23
HU226521B1 (en) 2009-03-30
CZ288657B6 (cs) 2001-08-15
YU49485B (sh) 2006-08-17
EE9600201A (et) 1997-06-16
CZ364696A3 (en) 1997-07-16
SA96170492B1 (ar) 2006-05-23
ZA9610405B (en) 1997-06-23
YU65096A (sh) 1998-12-23
CU22774A3 (es) 2002-07-24
DE19546249A1 (de) 1997-06-19
SK159196A3 (en) 1997-10-08
CN1160052A (zh) 1997-09-24
NO965298L (no) 1997-06-13
HUP9603428A3 (en) 1997-10-28
ATE221531T1 (de) 2002-08-15
DE59609501D1 (de) 2002-09-05
KR100525146B1 (ko) 2006-01-27
KR970042550A (ko) 1997-07-24
MY117492A (en) 2004-07-31
NO306725B1 (no) 1999-12-13
ID22625A (id) 1999-12-02
PL317415A1 (en) 1997-06-23
US5849752A (en) 1998-12-15
IL119795A0 (en) 1997-03-18
BR9605968A (pt) 1998-08-18
PL184885B1 (pl) 2003-01-31
DK0780390T3 (da) 2002-11-11
PT780390E (pt) 2002-11-29
TW411340B (en) 2000-11-11
SK282805B6 (sk) 2002-12-03
HUP9603428A2 (en) 1997-08-28
BG62258B1 (bg) 1999-06-30
CA2192418C (en) 2001-06-12
MA24342A1 (fr) 1998-07-01
RO119782B1 (ro) 2005-03-30
NO965298D0 (no) 1996-12-11
JP4104687B2 (ja) 2008-06-18
EP0780390A1 (de) 1997-06-25
HU9603428D0 (en) 1997-01-28
EE03474B1 (et) 2001-08-15
AU708006B2 (en) 1999-07-29
AR005009A1 (es) 1999-04-07
IL119795A (en) 1998-12-27
EP0780390B1 (de) 2002-07-31
CO4480105A1 (es) 1997-07-09
AU7421696A (en) 1997-06-19
TR199600970A2 (tr) 1997-06-21
SI0780390T1 (en) 2002-10-31
JPH09169757A (ja) 1997-06-30
SG47201A1 (en) 1998-03-20
MX9606325A (es) 1997-10-31
NL300109I1 (nl) 2003-02-03
IN185805B (sh) 2001-05-05
HRP960558A2 (en) 1998-02-28
UA35638C2 (uk) 2001-04-16
BG101043A (en) 1998-04-30

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
B1PR Patent granted
PPPP Transfer of rights

Owner name: BAYER HEALTHCARE AG, DE

PPPP Transfer of rights

Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, DE

PNAN Change of the applicant name, address/residence

Owner name: BAYER PHARMA AG, DE

PPPP Transfer of rights

Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE

ODRP Renewal fee for the maintenance of a patent

Payment date: 20151030

Year of fee payment: 20

PB20 Patent expired after termination of 20 years

Effective date: 20161125