HRP20212031T1 - Spojevi za moduliranje akvaporina - Google Patents

Spojevi za moduliranje akvaporina Download PDF

Info

Publication number
HRP20212031T1
HRP20212031T1 HRP20212031TT HRP20212031T HRP20212031T1 HR P20212031 T1 HRP20212031 T1 HR P20212031T1 HR P20212031T T HRP20212031T T HR P20212031TT HR P20212031 T HRP20212031 T HR P20212031T HR P20212031 T1 HRP20212031 T1 HR P20212031T1
Authority
HR
Croatia
Prior art keywords
triazol
acetamide
sulfanyl
thiadiazol
alkylene
Prior art date
Application number
HRP20212031TT
Other languages
English (en)
Croatian (hr)
Inventor
Johan EVENÄS
Joakim Larsson
Klaus DREISCH
Original Assignee
Apoglyx Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apoglyx Ab filed Critical Apoglyx Ab
Publication of HRP20212031T1 publication Critical patent/HRP20212031T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HRP20212031TT 2016-04-28 2017-04-28 Spojevi za moduliranje akvaporina HRP20212031T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16167378 2016-04-28
EP17720125.8A EP3448853B1 (en) 2016-04-28 2017-04-28 Compounds for modulating aquaporins
PCT/EP2017/060148 WO2017186893A1 (en) 2016-04-28 2017-04-28 Compounds for modulating aquaporins

Publications (1)

Publication Number Publication Date
HRP20212031T1 true HRP20212031T1 (hr) 2022-04-01

Family

ID=55854711

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20212031TT HRP20212031T1 (hr) 2016-04-28 2017-04-28 Spojevi za moduliranje akvaporina

Country Status (12)

Country Link
US (1) US10730865B2 (enExample)
EP (1) EP3448853B1 (enExample)
JP (1) JP6921118B2 (enExample)
CA (1) CA3022195C (enExample)
DK (1) DK3448853T3 (enExample)
ES (1) ES2902409T3 (enExample)
HR (1) HRP20212031T1 (enExample)
HU (1) HUE057193T2 (enExample)
LT (1) LT3448853T (enExample)
PL (1) PL3448853T3 (enExample)
PT (1) PT3448853T (enExample)
WO (1) WO2017186893A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111393444B (zh) * 2019-01-02 2022-10-28 上海迪赛诺化学制药有限公司 一种阿巴卡韦羟基醋酸酯的制备方法
WO2025137265A1 (en) 2023-12-20 2025-06-26 Saint Michael's College, Inc. Methods and compositions for reducing gliaptosis: macroglia-induced neuronal cell death
CN118001408B (zh) * 2024-04-08 2024-06-25 北京大学 一种水通道蛋白9磷酸化抑制剂的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US333792A (en) * 1886-01-05 Stop watch
WO2004089367A1 (en) 2003-04-11 2004-10-21 Novo Nordisk A/S Pharmaceutical use of substituted 1,2,4-triazoles
GB0704394D0 (en) * 2007-03-07 2007-04-11 Senexis Ltd Compounds
JP6671382B2 (ja) 2014-10-29 2020-03-25 アポグリクス アクツィエブーラーグApoGlyx AB 特に糖尿病の治療に有用である2−(1,2,4−トリアゾール−3−イルスルファニル)−n−1,3,4−チアジアゾール−2−イルアセトアミドの誘導体

Also Published As

Publication number Publication date
LT3448853T (lt) 2022-01-10
JP2019516677A (ja) 2019-06-20
ES2902409T3 (es) 2022-03-28
PL3448853T3 (pl) 2022-02-28
HUE057193T2 (hu) 2022-04-28
JP6921118B2 (ja) 2021-08-18
EP3448853B1 (en) 2021-11-17
PT3448853T (pt) 2021-12-30
US10730865B2 (en) 2020-08-04
WO2017186893A1 (en) 2017-11-02
US20190127360A1 (en) 2019-05-02
DK3448853T3 (da) 2021-12-06
EP3448853A1 (en) 2019-03-06
CA3022195A1 (en) 2017-11-02
CA3022195C (en) 2024-02-13

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