DK3448853T3 - Forbindelser til modulering af aquaporiner - Google Patents

Forbindelser til modulering af aquaporiner Download PDF

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Publication number
DK3448853T3
DK3448853T3 DK17720125.8T DK17720125T DK3448853T3 DK 3448853 T3 DK3448853 T3 DK 3448853T3 DK 17720125 T DK17720125 T DK 17720125T DK 3448853 T3 DK3448853 T3 DK 3448853T3
Authority
DK
Denmark
Prior art keywords
aquaporins
modulation
compounds
Prior art date
Application number
DK17720125.8T
Other languages
Danish (da)
English (en)
Inventor
Johan Evenäs
Joakim Larsson
Klaus Dreisch
Original Assignee
Apoglyx Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apoglyx Ab filed Critical Apoglyx Ab
Application granted granted Critical
Publication of DK3448853T3 publication Critical patent/DK3448853T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Emergency Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK17720125.8T 2016-04-28 2017-04-28 Forbindelser til modulering af aquaporiner DK3448853T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16167378 2016-04-28
PCT/EP2017/060148 WO2017186893A1 (en) 2016-04-28 2017-04-28 Compounds for modulating aquaporins

Publications (1)

Publication Number Publication Date
DK3448853T3 true DK3448853T3 (da) 2021-12-06

Family

ID=55854711

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17720125.8T DK3448853T3 (da) 2016-04-28 2017-04-28 Forbindelser til modulering af aquaporiner

Country Status (12)

Country Link
US (1) US10730865B2 (enExample)
EP (1) EP3448853B1 (enExample)
JP (1) JP6921118B2 (enExample)
CA (1) CA3022195C (enExample)
DK (1) DK3448853T3 (enExample)
ES (1) ES2902409T3 (enExample)
HR (1) HRP20212031T1 (enExample)
HU (1) HUE057193T2 (enExample)
LT (1) LT3448853T (enExample)
PL (1) PL3448853T3 (enExample)
PT (1) PT3448853T (enExample)
WO (1) WO2017186893A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111393444B (zh) * 2019-01-02 2022-10-28 上海迪赛诺化学制药有限公司 一种阿巴卡韦羟基醋酸酯的制备方法
WO2025137265A1 (en) 2023-12-20 2025-06-26 Saint Michael's College, Inc. Methods and compositions for reducing gliaptosis: macroglia-induced neuronal cell death
CN118001408B (zh) * 2024-04-08 2024-06-25 北京大学 一种水通道蛋白9磷酸化抑制剂的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US333792A (en) * 1886-01-05 Stop watch
WO2004089367A1 (en) 2003-04-11 2004-10-21 Novo Nordisk A/S Pharmaceutical use of substituted 1,2,4-triazoles
GB0704394D0 (en) * 2007-03-07 2007-04-11 Senexis Ltd Compounds
JP6671382B2 (ja) 2014-10-29 2020-03-25 アポグリクス アクツィエブーラーグApoGlyx AB 特に糖尿病の治療に有用である2−(1,2,4−トリアゾール−3−イルスルファニル)−n−1,3,4−チアジアゾール−2−イルアセトアミドの誘導体

Also Published As

Publication number Publication date
LT3448853T (lt) 2022-01-10
HRP20212031T1 (hr) 2022-04-01
JP2019516677A (ja) 2019-06-20
ES2902409T3 (es) 2022-03-28
PL3448853T3 (pl) 2022-02-28
HUE057193T2 (hu) 2022-04-28
JP6921118B2 (ja) 2021-08-18
EP3448853B1 (en) 2021-11-17
PT3448853T (pt) 2021-12-30
US10730865B2 (en) 2020-08-04
WO2017186893A1 (en) 2017-11-02
US20190127360A1 (en) 2019-05-02
EP3448853A1 (en) 2019-03-06
CA3022195A1 (en) 2017-11-02
CA3022195C (en) 2024-02-13

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