JP2019532092A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019532092A5 JP2019532092A5 JP2019522803A JP2019522803A JP2019532092A5 JP 2019532092 A5 JP2019532092 A5 JP 2019532092A5 JP 2019522803 A JP2019522803 A JP 2019522803A JP 2019522803 A JP2019522803 A JP 2019522803A JP 2019532092 A5 JP2019532092 A5 JP 2019532092A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- hydrogen
- heteroatoms selected
- substituted
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662414158P | 2016-10-28 | 2016-10-28 | |
| US62/414,158 | 2016-10-28 | ||
| PCT/US2017/058645 WO2018081488A1 (en) | 2016-10-28 | 2017-10-27 | Heterobicyclic compounds useful as modulators of il-12, il-23 and/or ifn alpha responses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019532092A JP2019532092A (ja) | 2019-11-07 |
| JP2019532092A5 true JP2019532092A5 (enExample) | 2020-11-12 |
| JP7145850B2 JP7145850B2 (ja) | 2022-10-03 |
Family
ID=60263169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019522803A Active JP7145850B2 (ja) | 2016-10-28 | 2017-10-27 | Ｉｌ－１２、ｉｌ－２３および／またはｉｆｎアルファ応答の調節剤として有用なヘテロ二環化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10781215B2 (enExample) |
| EP (1) | EP3532473B1 (enExample) |
| JP (1) | JP7145850B2 (enExample) |
| KR (1) | KR102477063B1 (enExample) |
| CN (1) | CN110114357B (enExample) |
| ES (1) | ES2895107T3 (enExample) |
| MA (1) | MA46620A (enExample) |
| WO (1) | WO2018081488A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3528816A4 (en) | 2016-10-21 | 2020-04-08 | Nimbus Lakshmi, Inc. | TYK2 INHIBITORS AND USES THEREOF |
| TW201940483A (zh) | 2018-03-12 | 2019-10-16 | 美商艾伯維有限公司 | 酪胺酸激酶２介導的傳訊之抑制劑 |
| TWI800696B (zh) * | 2018-12-10 | 2023-05-01 | 美商美國禮來大藥廠 | 7-(甲基胺基)吡唑并[1,5-a]嘧啶-3-甲醯胺衍生物 |
| CN111484480B (zh) * | 2019-01-29 | 2023-08-11 | 上海翰森生物医药科技有限公司 | 一种多环类衍生物抑制剂、其制备方法和应用 |
| EA202192625A1 (ru) * | 2019-03-26 | 2022-03-21 | Вентикс Байосайенсес, Инк. | Лиганды псевдокиназы tyk2 |
| CA3138473A1 (en) | 2019-04-30 | 2020-11-05 | Celgene Corporation | Combination therapies comprising apremilast and tyk2 inhibitors |
| MX2022005563A (es) | 2019-11-08 | 2022-08-19 | Ventyx Biosciences Inc | Ligandos de la pseudoquinasa tyk2. |
| WO2021108803A1 (en) * | 2019-11-26 | 2021-06-03 | Theravance Biopharma R&D Ip, Llc | Fused pyrimidine pyridinone compounds as jak inhibitors |
| CN116283993B (zh) * | 2021-12-20 | 2024-05-03 | 艾立康药业股份有限公司 | 一种嘧啶类化合物及其制备方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7176214B2 (en) | 2003-05-21 | 2007-02-13 | Bristol-Myers Squibb Company | Imidazo-fused oxazolo[4,5-β]pyridine and imidazo-fused thiazolo[4,5-β]pyridine based tricyclic compounds and pharmaceutical compositions comprising same |
| WO2008135232A1 (en) | 2007-05-02 | 2008-11-13 | Riccardo Cortese | Use and compositions of purine derivatives for the treatment of proliferative disorders |
| EP2188292B1 (en) | 2007-08-08 | 2013-05-29 | GlaxoSmithKline Intellectual Property Development Limited | 2- [ (2-{phenylamino}-1h-pyrrolo [2, 3-d]pyrimidin-4-yl) amino]benzamide derivatives as igf-1r inhibitors for the treatment of cancer |
| US8592432B2 (en) | 2008-04-07 | 2013-11-26 | Bei Chen | Compounds and compositions as protein kinase inhibitors |
| AU2009238590A1 (en) * | 2008-04-22 | 2009-10-29 | Portola Pharmaceuticals, Inc. | Inhibitors of protein kinases |
| US9540333B2 (en) * | 2012-11-08 | 2017-01-10 | Bristol-Myers Squibb Company | Alkyl amide-substituted pyrimidine compounds useful in the modulation of IL-12, IL-23 and/or IFNα |
| AR094537A1 (es) | 2013-11-07 | 2015-08-12 | Bristol Myers Squibb Co | COMPUESTOS DE PIRIDILO SUSTITUIDOS CON ALQUILAMIDA ÚTILES COMO MODULADORES DE LAS RESPUESTAS DE IL-12, IL-23 Y/O IFNa |
| EP3080131B1 (en) * | 2013-12-10 | 2018-10-10 | Bristol-Myers Squibb Company | Imidazopyridazine compounds useful as modulators of il-12, il-23 and/or ifn alpha responses |
| WO2015175813A1 (en) | 2014-05-14 | 2015-11-19 | The Regents Of The University Of Colorado, A Body Corporate | Heterocyclic hydroxamic acids as protein deacetylase inhibitors and dual protein deacetylase-protein kinase inhibitors and methods of use thereof |
| EP3528816A4 (en) | 2016-10-21 | 2020-04-08 | Nimbus Lakshmi, Inc. | TYK2 INHIBITORS AND USES THEREOF |
-
2017
- 2017-10-27 MA MA046620A patent/MA46620A/fr unknown
- 2017-10-27 WO PCT/US2017/058645 patent/WO2018081488A1/en not_active Ceased
- 2017-10-27 KR KR1020197014828A patent/KR102477063B1/ko active Active
- 2017-10-27 ES ES17794645T patent/ES2895107T3/es active Active
- 2017-10-27 US US16/344,459 patent/US10781215B2/en active Active
- 2017-10-27 EP EP17794645.6A patent/EP3532473B1/en active Active
- 2017-10-27 CN CN201780080803.4A patent/CN110114357B/zh active Active
- 2017-10-27 JP JP2019522803A patent/JP7145850B2/ja active Active