TWI800696B - 7-(甲基胺基)吡唑并[1,5-a]嘧啶-3-甲醯胺衍生物 - Google Patents

7-(甲基胺基)吡唑并[1,5-a]嘧啶-3-甲醯胺衍生物 Download PDF

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Publication number
TWI800696B
TWI800696B TW108143067A TW108143067A TWI800696B TW I800696 B TWI800696 B TW I800696B TW 108143067 A TW108143067 A TW 108143067A TW 108143067 A TW108143067 A TW 108143067A TW I800696 B TWI800696 B TW I800696B
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TW
Taiwan
Prior art keywords
pyrazolo
methylamino
pyrimidine
carboxamide derivatives
carboxamide
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TW108143067A
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English (en)
Other versions
TW202039497A (zh
Inventor
招根 陳
西奧多 科提斯 傑索普
Original Assignee
美商美國禮來大藥廠
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Publication of TW202039497A publication Critical patent/TW202039497A/zh
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Publication of TWI800696B publication Critical patent/TWI800696B/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
TW108143067A 2018-12-10 2019-11-27 7-(甲基胺基)吡唑并[1,5-a]嘧啶-3-甲醯胺衍生物 TWI800696B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862777395P 2018-12-10 2018-12-10
US62/777,395 2018-12-10

Publications (2)

Publication Number Publication Date
TW202039497A TW202039497A (zh) 2020-11-01
TWI800696B true TWI800696B (zh) 2023-05-01

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Family Applications (1)

Application Number Title Priority Date Filing Date
TW108143067A TWI800696B (zh) 2018-12-10 2019-11-27 7-(甲基胺基)吡唑并[1,5-a]嘧啶-3-甲醯胺衍生物

Country Status (8)

Country Link
US (1) US20220024933A1 (zh)
EP (1) EP3894412B1 (zh)
JP (1) JP7148728B2 (zh)
CN (1) CN113166163B (zh)
AR (1) AR117177A1 (zh)
ES (1) ES2939856T3 (zh)
TW (1) TWI800696B (zh)
WO (1) WO2020123225A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202108619SA (en) * 2019-02-07 2021-09-29 Ventyx Biosciences Inc Tyk2 pseudokinase ligands
JP2022529311A (ja) 2019-03-26 2022-06-21 ベンティックス バイオサイエンシーズ，インク． Ｔｙｋ２偽キナーゼリガンド
MX2022005563A (es) 2019-11-08 2022-08-19 Ventyx Biosciences Inc Ligandos de la pseudoquinasa tyk2.
WO2021162944A1 (en) * 2020-02-12 2021-08-19 Eli Lilly And Company Substituted 7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide derivatives
AR121251A1 (es) * 2020-02-12 2022-05-04 Lilly Co Eli Compuestos de 7-(metilamino)pirazolo[1,5-a]pirimidina-3-carboxamida
KR102550713B1 (ko) * 2021-01-18 2023-07-03 (주)바이오액츠 히드록시 치환된 트리아진을 포함하는 형광 화합물 및 이의 제조방법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060189632A1 (en) * 2003-02-28 2006-08-24 Kenichiro Kataoka Pyrazolo[1,5-A] pyrimidine derivatives
US20180325899A1 (en) * 2015-11-18 2018-11-15 Bristol-Myers Squibb Company Imidazopyridazine compounds useful as modulators of il-12, il-23 and/or ifn alpha responses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5578490B2 (ja) * 2008-12-26 2014-08-27 味の素株式会社 ピラゾロピリミジン化合物
CN110114357B (zh) * 2016-10-28 2022-05-31 百时美施贵宝公司 可用作IL-12、IL-23和/或IFNα反应的调节剂的杂双环化合物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060189632A1 (en) * 2003-02-28 2006-08-24 Kenichiro Kataoka Pyrazolo[1,5-A] pyrimidine derivatives
US20180325899A1 (en) * 2015-11-18 2018-11-15 Bristol-Myers Squibb Company Imidazopyridazine compounds useful as modulators of il-12, il-23 and/or ifn alpha responses

Also Published As

Publication number Publication date
EP3894412A1 (en) 2021-10-20
WO2020123225A1 (en) 2020-06-18
TW202039497A (zh) 2020-11-01
JP2022510357A (ja) 2022-01-26
CN113166163B (zh) 2023-04-07
JP7148728B2 (ja) 2022-10-05
EP3894412B1 (en) 2023-02-08
ES2939856T3 (es) 2023-04-27
CN113166163A (zh) 2021-07-23
US20220024933A1 (en) 2022-01-27
AR117177A1 (es) 2021-07-14

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