HRP20180362T1 - Postupak detektiranja nukleosoma koji sadrže varijante histona - Google Patents

Postupak detektiranja nukleosoma koji sadrže varijante histona

Info

Publication number
HRP20180362T1
HRP20180362T1 HRP20180362TT HRP20180362T HRP20180362T1 HR P20180362 T1 HRP20180362 T1 HR P20180362T1 HR P20180362T T HRP20180362T T HR P20180362TT HR P20180362 T HRP20180362 T HR P20180362T HR P20180362 T1 HRP20180362 T1 HR P20180362T1
Authority
HR
Croatia
Prior art keywords
histon
variations
detection procedure
procedure containing
nucleosome
Prior art date
Application number
HRP20180362TT
Other languages
English (en)
Croatian (hr)
Inventor
Jacob Vincent Micallef
Original Assignee
Belgian Volition Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Belgian Volition Sprl filed Critical Belgian Volition Sprl
Publication of HRP20180362T1 publication Critical patent/HRP20180362T1/hr

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875Nucleoproteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/101Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/102Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/101Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104Lupus erythematosus [SLE]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
    • G01N2800/122Chronic or obstructive airway disorders, e.g. asthma COPD
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/325Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
HRP20180362TT 2011-09-01 2012-08-31 Postupak detektiranja nukleosoma koji sadrže varijante histona HRP20180362T1 (hr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161530304P 2011-09-01 2011-09-01
GBGB1115098.4A GB201115098D0 (en) 2011-09-01 2011-09-01 Method for detecting nucleosomes containing histone variants
PCT/GB2012/052131 WO2013030579A1 (en) 2011-09-01 2012-08-31 Method for detecting nucleosomes containing histone variants
EP12762367.6A EP2751569B1 (en) 2011-09-01 2012-08-31 Method for detecting nucleosomes containing histone variants

Publications (1)

Publication Number Publication Date
HRP20180362T1 true HRP20180362T1 (hr) 2018-06-01

Family

ID=44882049

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20180362TT HRP20180362T1 (hr) 2011-09-01 2012-08-31 Postupak detektiranja nukleosoma koji sadrže varijante histona

Country Status (20)

Country Link
US (5) US9400276B2 (enExample)
EP (2) EP3301449B1 (enExample)
JP (2) JP2014529405A (enExample)
KR (1) KR102130855B1 (enExample)
CN (2) CN108107215A (enExample)
AU (1) AU2012300643B2 (enExample)
BR (1) BR112014004584B1 (enExample)
CA (1) CA2845994C (enExample)
DK (1) DK2751569T3 (enExample)
ES (2) ES2955475T3 (enExample)
GB (1) GB201115098D0 (enExample)
HR (1) HRP20180362T1 (enExample)
HU (1) HUE038517T2 (enExample)
MX (1) MX349561B (enExample)
PL (1) PL2751569T3 (enExample)
PT (1) PT2751569T (enExample)
RU (2) RU2014112348A (enExample)
SG (2) SG10201601168QA (enExample)
WO (1) WO2013030579A1 (enExample)
ZA (1) ZA201401296B (enExample)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201115095D0 (en) * 2011-09-01 2011-10-19 Singapore Volition Pte Ltd Method for detecting nucleosomes containing nucleotides
GB201115098D0 (en) 2011-09-01 2011-10-19 Belgian Volition Sa Method for detecting nucleosomes containing histone variants
EP3757210B1 (en) 2012-03-02 2022-08-24 Sequenom, Inc. Methods for enriching cancer nucleic acid from a biological sample
WO2013184930A2 (en) * 2012-06-06 2013-12-12 Trustees Of Princeton University Dna barcoding of designer mononucleosome and chromatin array libraries for the profiling of chromatin readers, writers, erasers, and modulators thereof
US11060145B2 (en) 2013-03-13 2021-07-13 Sequenom, Inc. Methods and compositions for identifying presence or absence of hypermethylation or hypomethylation locus
EP3736344A1 (en) 2014-03-13 2020-11-11 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
EP3809140A1 (en) 2014-10-29 2021-04-21 Belgian Volition SPRL Method for the enrichment of circulating tumor dna
WO2016128383A1 (en) * 2015-02-10 2016-08-18 B.R.A.H.M.S Gmbh Free histone proteins as biomarkers
GB201511542D0 (en) * 2015-07-01 2015-08-12 Singapore Volition Pte Ltd Use of cell free nucleosomes as biomarkers
GB201511512D0 (en) * 2015-07-01 2015-08-12 Singapore Volition Pte Ltd Use of cell-free nucleosomes as biomarkers
GB201518674D0 (en) 2015-10-21 2015-12-02 Singapore Volition Pte Ltd Method for detecting nuleosomes containing histone modifications and variants
GB201518665D0 (en) 2015-10-21 2015-12-02 Singapore Volition Pte Ltd Method for enrichment of cell free nucleosomes
GB201604806D0 (en) * 2016-03-22 2016-05-04 Singapore Volition Pte Ltd Method of identifying a cancer of unknown origin
GB201612815D0 (en) * 2016-07-25 2016-09-07 Belgian Volition Sa Novel combination test
TWI726009B (zh) * 2016-11-28 2021-05-01 比利時商比利時意志有限公司 用親和純化法分析生物樣品中源自腫瘤之無細胞核小體、分離生物樣品中純化之腫瘤dna、檢測生物樣品中源自腫瘤之核小體表觀遺傳表位或在動物或人類受試者中檢測癌症之方法或包括組蛋白h1結合劑之套組之用途
EP4119663B1 (en) 2016-12-09 2024-11-27 The Broad Institute, Inc. Crispr effector system based diagnostics
CN111108220B (zh) 2017-03-15 2024-11-19 博德研究所 用于病毒检测的基于crispr效应系统的诊断
GB201721569D0 (en) 2017-12-21 2018-02-07 Belgian Volition Sprl Method for the detection and treatment of colorectal adenomas
BR112020015093A2 (pt) 2018-01-29 2020-12-08 The Broad Institute, Inc. Diagnóstico baseado no sistema de efetor crispr
AU2019228625B2 (en) * 2018-03-01 2024-11-07 Epicypher, Inc. Quantification of nucleosome modifications using chemically-defined recombinant nucleosomes
CN119753091A (zh) 2018-04-02 2025-04-04 格里尔公司 用于扩增与癌症相关联的cfDNA分子的化验板
WO2020069350A1 (en) 2018-09-27 2020-04-02 Grail, Inc. Methylation markers and targeted methylation probe panel
GB201818963D0 (en) 2018-11-21 2019-01-09 Belgian Volition Sprl Methof for the detection of prostate cancer
GB201818965D0 (en) 2018-11-21 2019-01-09 Belgian Volition Sprl Method for the detection of colorectal cancer
GB201906201D0 (en) 2019-05-02 2019-06-19 Belgian Voltion Sprl Method for the detection of protate cancer
GB201906199D0 (en) 2019-05-02 2019-06-19 Belgian Volition Sprl Method for the detection of cancer
GB201912251D0 (en) 2019-08-27 2019-10-09 Belgian Volition Sprl Method of isolating circulating nucleosomes
WO2021038010A1 (en) 2019-08-27 2021-03-04 Belgian Volition Sprl Method of isolating circulating nucleosomes
BR112022010774A2 (pt) 2019-12-02 2022-08-23 Belgian Volition Srl Uso de nucleossomos livres de células como biomarcadores
EP4121551A1 (en) 2020-03-20 2023-01-25 Belgian Volition SRL Triaging method using cell free nucleosome levels
US20230355851A1 (en) 2020-09-21 2023-11-09 Belgian Volition SRL (BE/BE) Device for inline monitoring of free nucleosomes in blood
TW202238131A (zh) 2020-11-25 2022-10-01 比利時商比利時意志有限公司 測量無細胞核蛋白染色質片段之方法
TW202238132A (zh) 2020-12-08 2022-10-01 比利時商比利時意志有限公司 多發性硬化症之診斷方法
TW202242145A (zh) 2020-12-29 2022-11-01 比利時商比利時意志有限公司 核小體耗盡循環無細胞染色質片段之轉錄因子結合位點分析
TW202242130A (zh) 2020-12-29 2022-11-01 比利時商比利時意志有限公司 循環轉錄因子分析
TW202242146A (zh) 2021-01-13 2022-11-01 比利時商比利時意志有限公司 肺癌的檢測方法
GB202108185D0 (en) 2021-06-08 2021-07-21 Belgian Volition Sprl Standardisation of nucleosome assays using biologically derived calibrants
GB202108452D0 (en) 2021-06-14 2021-07-28 Belgian Volition Sprl Triaging method using cell free nucleosome levels
JP2024542996A (ja) 2021-10-29 2024-11-19 ベルジアン ボリション エスアールエル 均一系免疫アッセイ法
GB202117799D0 (en) 2021-12-09 2022-01-26 Belgian Volition Srl Method for the detection of blood cancer
EP4490323A1 (en) 2022-03-11 2025-01-15 Belgian Volition SRL Differential diagnosis method
GB202205212D0 (en) 2022-04-08 2022-05-25 Belgian Volition Sprl Method for transplant organ health assessment
WO2024042210A1 (en) 2022-08-25 2024-02-29 Belgian Volition Srl Method for measuring cell free chromatin
IL319155A (en) 2022-08-25 2025-04-01 Belgian Volition Srl A method for detecting dementia
WO2024133225A1 (en) 2022-12-19 2024-06-27 Belgian Volition Srl Calibration
EP4639165A1 (en) 2022-12-19 2025-10-29 Belgian Volition SRL Assessment of biological samples for nucleic acid analysis
GB202300607D0 (en) 2023-01-16 2023-03-01 Belgian Volition Srl Proteins and methods for isolating circulating nucleosomes
GB202303562D0 (en) 2023-03-10 2023-04-26 Belgian Volition Sprl Sample collection for liquid biopsy
WO2024213795A1 (en) 2023-04-14 2024-10-17 Belgian Volition Srl Diagnosis method using cell free nucleosome levels
WO2024223947A1 (en) 2023-04-28 2024-10-31 Belgian Volition Srl Use of cell free nucleosomes as biomarkers of carcinomas
GB202307768D0 (en) 2023-05-24 2023-07-05 Belgian Volition Srl Use of cell free nucleosomes as biomarkers
GB202310137D0 (en) 2023-07-03 2023-08-16 Belgian Volition Srl Method for the detection of cancer
WO2025012440A1 (en) 2023-07-13 2025-01-16 Belgian Volition Srl Method for detection of the potential of a body fluid sample to produce extracellular traps
WO2025061853A1 (en) 2023-09-19 2025-03-27 Belgian Volition Srl Lateral flow test device
WO2025093747A1 (en) 2023-11-02 2025-05-08 Belgian Volition Srl Novel rapid high-throughput method of netosis induction and inhibition with physiologically relevant molecules
WO2025181348A1 (en) 2024-03-01 2025-09-04 Belgian Volition Srl Method for determining the origin of circulating dna

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4276843B2 (ja) * 2001-03-23 2009-06-10 芳之 金井 モノヌクレオソーム及びその製造方法、ヌクレオソームに特異的な抗体の測定方法、自己免疫病診断方法、ヌクレオソームdna製造方法、dnaプレート、dnaプレート製造方法、並びに抗dna抗体測定法
US20040186274A1 (en) 2001-07-03 2004-09-23 Allis C. David Methylation of histone h4 at arginine 3
DE10207735A1 (de) * 2002-02-15 2003-08-28 Euroimmun Gmbh Verfahren zur Herstellung einer Nukleosomen-Präparation und deren Verwendung zur in vitro-Diagnose von Lupus erythematodes disseminatus (LED)
JP2005517431A (ja) * 2002-02-20 2005-06-16 ユニバーシティ オブ バージニア パテント ファウンデーション ヒストン修飾マーカーを利用した非侵襲的診断検査
GB0319376D0 (en) * 2003-08-18 2003-09-17 Chroma Therapeutics Ltd Histone modification detection
WO2005040814A1 (en) * 2003-10-14 2005-05-06 Cancer Research Technology Limited Methods and means of cancer detection by histone modification
EP1907856A2 (en) * 2005-07-27 2008-04-09 Oncomethylome Sciences SA Angiogenesis inhibition based upon icam 1 or junb expression levels
EP2189541A3 (en) * 2005-09-09 2010-09-08 University of Iowa Research Foundation Methods and reagents for treatment and diagnosis of age-related macular degeneration
US20110312897A1 (en) * 2008-09-17 2011-12-22 The Rockefeller University Cathepsin l proteolytically processes histone h3 during mouse embryonic stem cell differentiation
EP2270510A1 (en) * 2009-07-02 2011-01-05 EMBL (European Molecular Biology Laboratory) Diagnostic method for predicting the risk of cancer recurrence based on Histone macroH2A isoforms
GB201115098D0 (en) 2011-09-01 2011-10-19 Belgian Volition Sa Method for detecting nucleosomes containing histone variants

Also Published As

Publication number Publication date
GB201115098D0 (en) 2011-10-19
EP2751569B1 (en) 2017-12-27
HK1199758A1 (en) 2015-07-17
MX2014002444A (es) 2014-10-23
EP3301449C0 (en) 2023-08-09
EP3301449B1 (en) 2023-08-09
US20160299152A1 (en) 2016-10-13
EP2751569A1 (en) 2014-07-09
AU2012300643B2 (en) 2017-06-15
US20140206014A1 (en) 2014-07-24
HK1253354A1 (en) 2019-06-14
BR112014004584B1 (pt) 2021-07-06
US20190120853A1 (en) 2019-04-25
CA2845994C (en) 2020-10-13
WO2013030579A1 (en) 2013-03-07
CA2845994A1 (en) 2013-03-07
AU2012300643A1 (en) 2014-03-06
RU2018101257A (ru) 2019-02-21
SG10201601168QA (en) 2016-03-30
KR20140078638A (ko) 2014-06-25
RU2716494C2 (ru) 2020-03-12
RU2014112348A (ru) 2015-10-10
ZA201401296B (en) 2014-12-23
RU2018101257A3 (enExample) 2019-02-21
HUE038517T2 (hu) 2018-10-29
US10184945B2 (en) 2019-01-22
ES2662380T3 (es) 2018-04-06
KR102130855B1 (ko) 2020-07-09
MX349561B (es) 2017-08-02
EP3301449A1 (en) 2018-04-04
JP2014529405A (ja) 2014-11-13
US20230116530A1 (en) 2023-04-13
ES2955475T3 (es) 2023-12-01
CN104053993A (zh) 2014-09-17
US9400276B2 (en) 2016-07-26
JP6494703B2 (ja) 2019-04-03
BR112014004584A2 (pt) 2017-05-16
DK2751569T3 (en) 2018-03-12
PT2751569T (pt) 2018-03-28
US20200341006A1 (en) 2020-10-29
PL2751569T3 (pl) 2018-06-29
CN108107215A (zh) 2018-06-01
SG11201400202SA (en) 2014-03-28
JP2017215338A (ja) 2017-12-07

Similar Documents

Publication Publication Date Title
HRP20180362T1 (hr) Postupak detektiranja nukleosoma koji sadrže varijante histona
SMT201700109B (it) Inibitori di istone demetilasi
EP2663857A4 (en) METHOD OF DETECTION OF PROTEINS
HRP20180233T1 (hr) Intranazalni farmaceutski oblici doziranja koji sadrže nalokson
PL2831279T3 (pl) Szybkie wykrywanie aneuploidii
DE112012004412T8 (de) Lichterfassungsvorrichtung
BR112014004902A2 (pt) peptídeos
EP2824465A4 (en) Defect detection device
EP2681618A4 (en) DISPLAY DEVICE
EP2685271A4 (en) MAGNETIC DETECTION DEVICE
DE112012002058T8 (de) Ionenerfassung
EP2900475A4 (en) Drop detection
EP2716064A4 (en) CONTRAPTION
EP2720262A4 (en) COOLER
IL227954B (en) Terahertz detection cell
EP2661633A4 (en) PROOF OF PROTEOLYSIS
EP2738081A4 (en) DEVICE FOR PREVENTING THE FLIP OF A LIQUID
BR112013029333A2 (pt) detecção de nível
BR112013014767A2 (pt) gaxeta semicorrugada
DK2520760T3 (da) Tætning
EP2585688A4 (en) SENSOR DEVICE
DE112012003417A5 (de) Strommessgerät
FR2984104B1 (fr) Presentoir
DK2607881T3 (da) Koncentrationsapparat
FR2978337B1 (fr) Presentoir