MX349561B - Método para detectar nucleosomas que contienen variantes de histonas. - Google Patents

Método para detectar nucleosomas que contienen variantes de histonas.

Info

Publication number
MX349561B
MX349561B MX2014002444A MX2014002444A MX349561B MX 349561 B MX349561 B MX 349561B MX 2014002444 A MX2014002444 A MX 2014002444A MX 2014002444 A MX2014002444 A MX 2014002444A MX 349561 B MX349561 B MX 349561B
Authority
MX
Mexico
Prior art keywords
histone variants
nucleosomes containing
containing histone
detecting
nucleosomes
Prior art date
Application number
MX2014002444A
Other languages
English (en)
Other versions
MX2014002444A (es
Inventor
Jacob Vincent Micallef
Original Assignee
Singapore Volition Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Singapore Volition Pte Ltd filed Critical Singapore Volition Pte Ltd
Publication of MX2014002444A publication Critical patent/MX2014002444A/es
Publication of MX349561B publication Critical patent/MX349561B/es

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875—Nucleoproteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/102—Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104—Lupus erythematosus [SLE]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases
    • G01N2800/122—Chronic or obstructive airway disorders, e.g. asthma COPD
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a un método para detectar y medir la presencia de mono-nucleosomas y oligo-nucleosomas y nucleosomas que contienen variantes de histona particulares y el uso de estas mediciones para la detección y diagnóstico de enfermedad; La invención también se relaciona con un método para identificar biomarcadores de variante de histona para la detección y diagnóstico de enfermedad y con biomarcadores identificados por el método.
MX2014002444A 2011-09-01 2012-08-31 Método para detectar nucleosomas que contienen variantes de histonas. MX349561B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161530304P 2011-09-01 2011-09-01
GBGB1115098.4A GB201115098D0 (en) 2011-09-01 2011-09-01 Method for detecting nucleosomes containing histone variants
PCT/GB2012/052131 WO2013030579A1 (en) 2011-09-01 2012-08-31 Method for detecting nucleosomes containing histone variants

Publications (2)

Publication Number Publication Date
MX2014002444A MX2014002444A (es) 2014-10-23
MX349561B true MX349561B (es) 2017-08-02

Family

ID=44882049

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014002444A MX349561B (es) 2011-09-01 2012-08-31 Método para detectar nucleosomas que contienen variantes de histonas.

Country Status (21)

Country Link
US (5) US9400276B2 (es)
EP (2) EP2751569B1 (es)
JP (2) JP2014529405A (es)
KR (1) KR102130855B1 (es)
CN (2) CN104053993A (es)
AU (1) AU2012300643B2 (es)
BR (1) BR112014004584B1 (es)
CA (1) CA2845994C (es)
DK (1) DK2751569T3 (es)
ES (2) ES2662380T3 (es)
GB (1) GB201115098D0 (es)
HK (2) HK1199758A1 (es)
HR (1) HRP20180362T1 (es)
HU (1) HUE038517T2 (es)
MX (1) MX349561B (es)
PL (1) PL2751569T3 (es)
PT (1) PT2751569T (es)
RU (2) RU2014112348A (es)
SG (2) SG10201601168QA (es)
WO (1) WO2013030579A1 (es)
ZA (1) ZA201401296B (es)

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Publication number Publication date
WO2013030579A1 (en) 2013-03-07
CN108107215A (zh) 2018-06-01
CA2845994C (en) 2020-10-13
RU2014112348A (ru) 2015-10-10
ZA201401296B (en) 2014-12-23
HK1253354A1 (zh) 2019-06-14
JP2017215338A (ja) 2017-12-07
HK1199758A1 (en) 2015-07-17
SG10201601168QA (en) 2016-03-30
JP6494703B2 (ja) 2019-04-03
ES2662380T3 (es) 2018-04-06
RU2018101257A (ru) 2019-02-21
ES2955475T3 (es) 2023-12-01
SG11201400202SA (en) 2014-03-28
HRP20180362T1 (hr) 2018-06-01
US20230116530A1 (en) 2023-04-13
GB201115098D0 (en) 2011-10-19
RU2716494C2 (ru) 2020-03-12
EP3301449A1 (en) 2018-04-04
PT2751569T (pt) 2018-03-28
US9400276B2 (en) 2016-07-26
CA2845994A1 (en) 2013-03-07
BR112014004584B1 (pt) 2021-07-06
US20160299152A1 (en) 2016-10-13
EP2751569A1 (en) 2014-07-09
RU2018101257A3 (es) 2019-02-21
US20190120853A1 (en) 2019-04-25
PL2751569T3 (pl) 2018-06-29
MX2014002444A (es) 2014-10-23
EP3301449C0 (en) 2023-08-09
AU2012300643A1 (en) 2014-03-06
EP3301449B1 (en) 2023-08-09
BR112014004584A2 (pt) 2017-05-16
CN104053993A (zh) 2014-09-17
HUE038517T2 (hu) 2018-10-29
KR20140078638A (ko) 2014-06-25
DK2751569T3 (en) 2018-03-12
US20200341006A1 (en) 2020-10-29
EP2751569B1 (en) 2017-12-27
US20140206014A1 (en) 2014-07-24
AU2012300643B2 (en) 2017-06-15
JP2014529405A (ja) 2014-11-13
US10184945B2 (en) 2019-01-22
KR102130855B1 (ko) 2020-07-09

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