HRP20180282T1 - Imunoterapija na bazi indoleamin 2, 3-dioksigenaze - Google Patents

Imunoterapija na bazi indoleamin 2, 3-dioksigenaze Download PDF

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Publication number
HRP20180282T1
HRP20180282T1 HRP20180282TT HRP20180282T HRP20180282T1 HR P20180282 T1 HRP20180282 T1 HR P20180282T1 HR P20180282T T HRP20180282T T HR P20180282TT HR P20180282 T HRP20180282 T HR P20180282T HR P20180282 T1 HRP20180282 T1 HR P20180282T1
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HR
Croatia
Prior art keywords
adjuvant
seq
use according
vaccine preparation
peptide
Prior art date
Application number
HRP20180282TT
Other languages
English (en)
Croatian (hr)
Inventor
Mads Hald Andersen
Per Thor Straten
Original Assignee
Io Biotech Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Io Biotech Aps filed Critical Io Biotech Aps
Publication of HRP20180282T1 publication Critical patent/HRP20180282T1/hr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001154—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/11—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of two atoms of oxygen (1.13.11)
    • C12Y113/11052—Indoleamine 2,3-dioxygenase (1.13.11.52), i.e. indoleamine 2,3-dioxygenase 1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
HRP20180282TT 2008-04-17 2009-04-17 Imunoterapija na bazi indoleamin 2, 3-dioksigenaze HRP20180282T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200800565 2008-04-17
PCT/DK2009/000095 WO2009143843A1 (en) 2008-04-17 2009-04-17 Indoleamine 2, 3-dioxygenase based immunotherapy
EP09753556.1A EP2280721B1 (en) 2008-04-17 2009-04-17 Indoleamine 2, 3-dioxygenase based immunotherapy

Publications (1)

Publication Number Publication Date
HRP20180282T1 true HRP20180282T1 (hr) 2018-03-23

Family

ID=40873320

Family Applications (2)

Application Number Title Priority Date Filing Date
HRP20180282TT HRP20180282T1 (hr) 2008-04-17 2009-04-17 Imunoterapija na bazi indoleamin 2, 3-dioksigenaze
HRP20210766TT HRP20210766T1 (hr) 2008-04-17 2021-05-13 Imunoterapija na bazi indoleamin 2, 3-dioksigenaze

Family Applications After (1)

Application Number Title Priority Date Filing Date
HRP20210766TT HRP20210766T1 (hr) 2008-04-17 2021-05-13 Imunoterapija na bazi indoleamin 2, 3-dioksigenaze

Country Status (20)

Country Link
US (7) US9433666B2 (enExample)
EP (3) EP2280721B1 (enExample)
JP (2) JP2011520783A (enExample)
CN (2) CN104056261B (enExample)
AU (1) AU2009253539B2 (enExample)
CA (1) CA2721150C (enExample)
CY (2) CY1120352T1 (enExample)
DK (2) DK2280721T3 (enExample)
ES (2) ES2870596T3 (enExample)
HR (2) HRP20180282T1 (enExample)
HU (2) HUE037973T2 (enExample)
IL (1) IL208781A (enExample)
LT (2) LT2280721T (enExample)
NO (1) NO2280721T3 (enExample)
NZ (1) NZ588757A (enExample)
PL (2) PL3320912T3 (enExample)
PT (2) PT2280721T (enExample)
SI (2) SI2280721T1 (enExample)
WO (1) WO2009143843A1 (enExample)
ZA (1) ZA201008056B (enExample)

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Also Published As

Publication number Publication date
CA2721150A1 (en) 2009-12-03
DK3320912T3 (da) 2021-05-31
JP6016966B2 (ja) 2016-10-26
DK2280721T3 (da) 2018-01-29
CY1120352T1 (el) 2019-07-10
CY1124279T1 (el) 2022-07-22
PL3320912T3 (pl) 2021-10-25
NZ588757A (en) 2012-05-25
ZA201008056B (en) 2011-07-27
EP2280721A1 (en) 2011-02-09
AU2009253539A1 (en) 2009-12-03
PL2280721T3 (pl) 2018-04-30
PT2280721T (pt) 2018-02-16
CN102088994B (zh) 2014-06-25
CN104056261B (zh) 2017-01-11
CN102088994A (zh) 2011-06-08
US11324813B2 (en) 2022-05-10
US20250319159A1 (en) 2025-10-16
LT3320912T (lt) 2021-07-12
US12233103B2 (en) 2025-02-25
US20230233657A1 (en) 2023-07-27
ES2870596T3 (es) 2021-10-27
JP2015129182A (ja) 2015-07-16
US20220202922A1 (en) 2022-06-30
LT2280721T (lt) 2018-02-12
EP3320912B1 (en) 2021-03-31
EP3320912A1 (en) 2018-05-16
US20110318372A1 (en) 2011-12-29
HRP20210766T1 (hr) 2021-07-23
PT3320912T (pt) 2021-05-24
US20220249641A1 (en) 2022-08-11
NO2280721T3 (enExample) 2018-04-14
US20170049868A1 (en) 2017-02-23
US11648302B2 (en) 2023-05-16
SI3320912T1 (sl) 2021-08-31
US9433666B2 (en) 2016-09-06
HUE055338T2 (hu) 2021-11-29
US10258678B2 (en) 2019-04-16
IL208781A0 (en) 2010-12-30
ES2657963T3 (es) 2018-03-07
SI2280721T1 (en) 2018-02-28
AU2009253539B2 (en) 2014-03-20
HUE037973T2 (hu) 2018-09-28
CN104056261A (zh) 2014-09-24
JP2011520783A (ja) 2011-07-21
US20190201512A1 (en) 2019-07-04
EP3915570A1 (en) 2021-12-01
CA2721150C (en) 2017-09-26
EP2280721B1 (en) 2017-11-15
IL208781A (en) 2017-09-28
WO2009143843A1 (en) 2009-12-03

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