HRP20161107T1 - Derivati n3-supstituiranog-n1-sulfonil-5-fluoropirimidinona - Google Patents
Derivati n3-supstituiranog-n1-sulfonil-5-fluoropirimidinona Download PDFInfo
- Publication number
- HRP20161107T1 HRP20161107T1 HRP20161107TT HRP20161107T HRP20161107T1 HR P20161107 T1 HRP20161107 T1 HR P20161107T1 HR P20161107T T HRP20161107T T HR P20161107TT HR P20161107 T HRP20161107 T HR P20161107T HR P20161107 T1 HRP20161107 T1 HR P20161107T1
- Authority
- HR
- Croatia
- Prior art keywords
- plant
- alkyl
- substituted
- haloalkyl
- alkylamino
- Prior art date
Links
- 241000196324 Embryophyta Species 0.000 claims 7
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 3
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 claims 2
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 2
- 125000004448 alkyl carbonyl group Chemical group 0.000 claims 2
- 244000053095 fungal pathogen Species 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 125000005843 halogen group Chemical group 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000006559 (C1-C3) alkylamino group Chemical group 0.000 claims 1
- 125000004767 (C1-C4) haloalkoxy group Chemical group 0.000 claims 1
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims 1
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 claims 1
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims 1
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 claims 1
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims 1
- 125000006771 (C1-C6) haloalkylthio group Chemical group 0.000 claims 1
- 235000017060 Arachis glabrata Nutrition 0.000 claims 1
- 235000010777 Arachis hypogaea Nutrition 0.000 claims 1
- 244000105624 Arachis hypogaea Species 0.000 claims 1
- 235000018262 Arachis monticola Nutrition 0.000 claims 1
- 241000219310 Beta vulgaris subsp. vulgaris Species 0.000 claims 1
- 241000530549 Cercospora beticola Species 0.000 claims 1
- 241000131448 Mycosphaerella Species 0.000 claims 1
- 241001281801 Mycosphaerella arachidis Species 0.000 claims 1
- 206010039509 Scab Diseases 0.000 claims 1
- 235000021536 Sugar beet Nutrition 0.000 claims 1
- 241000209140 Triticum Species 0.000 claims 1
- 235000021307 Triticum Nutrition 0.000 claims 1
- 241000228452 Venturia inaequalis Species 0.000 claims 1
- 241001360088 Zymoseptoria tritici Species 0.000 claims 1
- 125000004457 alkyl amino carbonyl group Chemical group 0.000 claims 1
- 125000004414 alkyl thio group Chemical group 0.000 claims 1
- 239000012876 carrier material Substances 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 125000004663 dialkyl amino group Chemical group 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 125000004995 haloalkylthio group Chemical group 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- -1 nitro, hydroxyl Chemical group 0.000 claims 1
- 235000020232 peanut Nutrition 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 239000002689 soil Substances 0.000 claims 1
- 125000004665 trialkylsilyl group Chemical group 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Engineering & Computer Science (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (4)
1. Spoj formule I
[image]
naznačen time, da R1jest:
H;
R2 jest:
C1-C6 alkil po izboru supstituiran s R4; benzil po izboru supstituiran s 1-3 R5;
R3 jest -S(O)2R6;
R4 jest nezavisno halogen, C1-C6 alkil, C1-C4 haloalkil, C1-C4 alkoksi, C1-C4 haloalkoksi, C1-C4 alkiltio, C1-C4 haloalkiltio, amino, C1-C3 alkilamino, C2-C6 alkoksikarbonil, C2-C6 alkilkarbonil, C2-C6 alkilaminokarbonil, hidroksil ili C3-C6 trialkilsilil;
R5 jest nezavisno halogen, C1-C6 alkil, C1-C6 haloalkil, C1-C6 alkoksi, C1-C6 haloalkoksi, C1-C6 alkiltio, C1-C6 haloalkiltio, amino, C1-C6 alkilamino, C2-C6 dialkilamino, C2-C6 alkoksikarbonil ili C2-C6 alkilkarbonil, nitro, hidroksil ili cijano;
R6 jest C1-C6 alkil, C1-C6 haloalkil, amino, C1-C6 alkilamino, C2-C6 dialkilamino, fenil ili benzil, u čemu svaki od fenila ili benzila po izboru može biti supstituiran s 1-3 R5, ili 5- ili 6-članim zasićenim ili nezasićenim prstenom koji sadrži 1-3 heteroatoma, u čemu svaki prsten po izboru može biti supstituiran s 1-3 R5;
ili njegova sol ili hidrat.
2. Sastav za kontrolu gljivičnog patogena, naznačen time, da uključuje spoj prema patentnom zahtjevu 1 i fitološki prihvatljiv materijal nosioca.
3. Sastav prema patentnom zahtjevu 2, naznačen time da gljivični patogen jest jabučna krastavost (Venturia inaequalis), pjegavost lista pšenice (Septoria tritici), pjegavost lista šećernih repa (Cercospora beticola), pjegavost lista kikirikija (Cercospora arachidicola) i crna sigatoka (Mycosphaerella Jijiensis).
4. Postupak za kontrolu i sprječavanje gljivičnog napada na biljku, naznačen time da, postupak uključuje stupnjeve:
primjena fungicidno učinkovite količine barem jednog spoja prema patentnom zahtjevu 1 na barem jednu biljku, na područje neposredno uz biljku, na tlo prilagođeno da podupire rast biljke, na korijen biljke, na lišće biljke i na sjeme prilagođeno proizvodnji biljke.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32785510P | 2010-04-26 | 2010-04-26 | |
| EP11775446.5A EP2563129B1 (en) | 2010-04-26 | 2011-04-20 | N3-substituted-n1-sulfonyl-5-fluoropyrimidinone derivatives |
| PCT/US2011/033203 WO2011137002A1 (en) | 2010-04-26 | 2011-04-20 | N3-substituted-n1-sulfonyl-5-fluoropyrimidinone derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20161107T1 true HRP20161107T1 (hr) | 2016-12-30 |
Family
ID=44816310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20161107TT HRP20161107T1 (hr) | 2010-04-26 | 2016-08-30 | Derivati n3-supstituiranog-n1-sulfonil-5-fluoropirimidinona |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US8263603B2 (hr) |
| EP (1) | EP2563129B1 (hr) |
| JP (1) | JP5784705B2 (hr) |
| KR (1) | KR101793766B1 (hr) |
| CN (1) | CN102946730B (hr) |
| AU (1) | AU2011245544B2 (hr) |
| BR (1) | BR112012027439B1 (hr) |
| CA (1) | CA2797226C (hr) |
| CL (1) | CL2012002979A1 (hr) |
| CO (1) | CO6592042A2 (hr) |
| CR (1) | CR20120584A (hr) |
| CY (1) | CY1117956T1 (hr) |
| DK (1) | DK2563129T3 (hr) |
| EC (1) | ECSP12012302A (hr) |
| ES (1) | ES2588742T3 (hr) |
| GT (1) | GT201200289A (hr) |
| HK (1) | HK1182594A1 (hr) |
| HN (1) | HN2012002272A (hr) |
| HR (1) | HRP20161107T1 (hr) |
| HU (1) | HUE029489T2 (hr) |
| IL (1) | IL222646A (hr) |
| LT (1) | LT2563129T (hr) |
| ME (1) | ME02530B (hr) |
| MX (1) | MX2012012530A (hr) |
| NZ (1) | NZ603151A (hr) |
| PL (1) | PL2563129T3 (hr) |
| PT (1) | PT2563129T (hr) |
| RS (1) | RS55239B1 (hr) |
| RU (1) | RU2562840C2 (hr) |
| SI (1) | SI2563129T1 (hr) |
| SM (1) | SMT201600298B (hr) |
| UA (1) | UA108101C2 (hr) |
| WO (1) | WO2011137002A1 (hr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011017547A1 (en) * | 2009-08-07 | 2011-02-10 | Dow Agrosciences Llc | N1-sulfonyl-5-fluoropyrimidinone derivatives |
| EP2945635A4 (en) * | 2012-12-28 | 2016-05-25 | Dow Agrosciences Llc | 1- (BENZOYL-SUBSTITUTED) -5-FLUORO-4-IMINO-3-METHYL-3,4-DIHYDROPYRIMIDIN-2 (1H) -ONE DERIVATIVES |
| US9622474B2 (en) | 2012-12-28 | 2017-04-18 | Adama Makhteshim Ltd. | N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1(2H)-carboxylate derivatives |
| AU2013370490B2 (en) * | 2012-12-28 | 2018-05-10 | Adama Makhteshim Ltd. | N-(substituted)-5-fluoro-4-imino-3-methyl-2-oxo-3,4-dihydropyrimidine-1 (2H)-carboxamide derivatives |
| US9642368B2 (en) * | 2012-12-31 | 2017-05-09 | Adama Makhteshim Ltd. | 3-alkyl-5-fluoro-4-substituted-imino-3,4-dihydropyrimidin-2(1H)-one derivatives as fungicides |
| EA030030B1 (ru) * | 2013-12-31 | 2018-06-29 | Адама Мактешим Лтд. | Синергетические фунгицидные смеси и синергетические фунгицидные композиции для борьбы с грибами |
| NZ722438A (en) * | 2013-12-31 | 2018-01-26 | Adama Makhteshim Ltd | 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation |
| MA41272A (fr) * | 2014-12-23 | 2017-10-31 | Adama Makhteshim Ltd | 5-fluoro-4-imino-3-(alkyle/alkyle substitué)-1-(arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one en tant que traitement des semences |
| JP6862939B2 (ja) * | 2016-03-11 | 2021-04-21 | 住友化学株式会社 | 植物病害防除組成物及び植物病害防除方法 |
| CA3050864A1 (en) * | 2017-01-26 | 2018-08-02 | Mitsui Chemicals Agro, Inc. | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients |
| JP7168556B2 (ja) | 2017-04-10 | 2022-11-09 | 三井化学アグロ株式会社 | ピリドン化合物およびそれを有効成分とする農園芸用殺菌剤 |
| TWI793113B (zh) | 2017-04-10 | 2023-02-21 | 日商三井化學Agro股份有限公司 | 吡啶酮化合物及以吡啶酮化合物作為有效成分的農園藝用殺菌劑 |
| UA126399C2 (uk) | 2017-04-11 | 2022-09-28 | Міцуі Кемікалз Агро, Інк. | Піридони і сільськогосподарські і садові фунгіциди, які їх містять, як активні інгредієнти |
| EP3636636B1 (en) | 2017-06-08 | 2022-07-06 | Mitsui Chemicals Agro, Inc. | Pyridone compound and agricultural and horticultural fungicide |
| AU2018320492C1 (en) | 2017-07-17 | 2023-07-13 | Adama Makhteshim Ltd. | Polymorphs of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2-one |
| EP3828177B1 (en) | 2018-07-25 | 2023-11-29 | Mitsui Chemicals Crop & Life Solutions, Inc. | Pyridone compound and agricultural and horticultural fungicide having this as active component |
| BR112021008755A2 (pt) | 2018-11-05 | 2021-08-10 | Adama Makhteshim Ltd. | misturas e composições contendo 5-fluoro-4-imino-3- metil-1-tosil-3,4-dihidropirimidina-2-ona, e métodos de uso. |
| UY38798A (es) | 2019-07-22 | 2021-02-26 | Adama Makhteshim Ltd | Combinaciones, mezclas y composiciones fungicidas y usos de las mismas |
| MX2022011088A (es) * | 2020-03-09 | 2022-09-29 | Adama Makhteshim Ltd | Procedimiento para preparar 5-fluoro-4-imino-3-metil-1-(tolueno-4- sulfonil)-3,4-dihidro-1h-pirimidin-2-ona. |
| CA3177682A1 (en) | 2020-05-04 | 2021-11-11 | Adama Makhteshim Ltd. | Mixtures and compositions comprising 5-fluoro-4-imino-3- methyl-1-tosyl-3,4-dihydropyrimidin-2-one, and methods of use thereof |
| MX2023000335A (es) | 2020-07-08 | 2023-05-04 | Adama Makhteshim Ltd | Mezclas fungicidas. |
| WO2022162591A1 (en) | 2021-01-27 | 2022-08-04 | Adama Makhteshim Ltd. | 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1 h)-one for controlling plant diseases |
| WO2022234487A1 (en) | 2021-05-04 | 2022-11-10 | Adama Makhteshim Ltd. | Crystalline forms of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4- dihydropyrimidin-2-one, and mixtures, compositions and methods of use thereof |
| IL311455A (en) * | 2021-09-15 | 2024-05-01 | Adama Makhteshim Ltd | Method for preparing 5-fluoro-4-imino-3-methyl-1-(toluene-4-sulfonyl)-3,4-dihydro-H1-pyrimidin-2-one |
| CN118555910A (zh) * | 2022-01-12 | 2024-08-27 | 安道麦马克西姆有限公司 | 包含含有邻苯二甲酰亚胺杀真菌剂的组合的杀真菌混合物 |
| AU2023227455A1 (en) | 2022-03-03 | 2024-09-19 | Adama Makhteshim Ltd. | Fungicidal combinations, mixtures and compositions and uses thereof |
| WO2023228148A1 (en) | 2022-05-26 | 2023-11-30 | Adama Makhteshim Ltd. | Fungicidal combinations, mixtures and compositions and uses thereof |
| WO2024184859A1 (en) | 2023-03-09 | 2024-09-12 | Conese Salvatore | Fungicidal combinations, mixtures and compositions and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP970239B1 (en) * | 1997-05-09 | 2004-04-30 | Inst Ru Er Bouekovic | Process for the preparation of sulfonyl-pyrimidine derivatives with antitumor activity |
| GT199900185A (es) * | 1998-11-06 | 2001-04-18 | Novedosa pirimidin-4-enamina como fungicida. | |
| US20090163567A1 (en) * | 2005-11-22 | 2009-06-25 | Ishihara Sangyo Kaisha, Ltd | Germicide composition for agricultural and gardening applications and method for controlling plant disease |
| PL2562162T3 (pl) * | 2008-01-22 | 2016-01-29 | Dow Agrosciences Llc | Pochodne N-cyjano-4-amino-5-fluoropirymidyny jako fungicydy |
| ES2456272T3 (es) * | 2008-08-01 | 2014-04-21 | Dow Agrosciences Llc | Uso de 5-fluorocitosina como un fungicida |
| WO2011017547A1 (en) * | 2009-08-07 | 2011-02-10 | Dow Agrosciences Llc | N1-sulfonyl-5-fluoropyrimidinone derivatives |
| UA112284C2 (uk) * | 2009-08-07 | 2016-08-25 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Похідні 5-фторпіримідинону |
-
2011
- 2011-04-20 KR KR1020127030690A patent/KR101793766B1/ko active IP Right Grant
- 2011-04-20 PT PT117754465T patent/PT2563129T/pt unknown
- 2011-04-20 PL PL11775446T patent/PL2563129T3/pl unknown
- 2011-04-20 AU AU2011245544A patent/AU2011245544B2/en active Active
- 2011-04-20 MX MX2012012530A patent/MX2012012530A/es active IP Right Grant
- 2011-04-20 SI SI201130933A patent/SI2563129T1/sl unknown
- 2011-04-20 DK DK11775446.5T patent/DK2563129T3/en active
- 2011-04-20 UA UAA201213412A patent/UA108101C2/ru unknown
- 2011-04-20 NZ NZ603151A patent/NZ603151A/xx unknown
- 2011-04-20 RU RU2012150293/13A patent/RU2562840C2/ru active
- 2011-04-20 ME MEP-2016-177A patent/ME02530B/me unknown
- 2011-04-20 RS RS20160719A patent/RS55239B1/sr unknown
- 2011-04-20 CA CA2797226A patent/CA2797226C/en active Active
- 2011-04-20 US US13/090,616 patent/US8263603B2/en active Active
- 2011-04-20 LT LTEP11775446.5T patent/LT2563129T/lt unknown
- 2011-04-20 JP JP2013508042A patent/JP5784705B2/ja active Active
- 2011-04-20 BR BR112012027439-2A patent/BR112012027439B1/pt active IP Right Grant
- 2011-04-20 EP EP11775446.5A patent/EP2563129B1/en active Active
- 2011-04-20 ES ES11775446.5T patent/ES2588742T3/es active Active
- 2011-04-20 WO PCT/US2011/033203 patent/WO2011137002A1/en active Application Filing
- 2011-04-20 HU HUE11775446A patent/HUE029489T2/en unknown
- 2011-04-20 CN CN201180031680.8A patent/CN102946730B/zh active Active
-
2012
- 2012-10-23 IL IL222646A patent/IL222646A/en active IP Right Grant
- 2012-10-24 HN HN2012002272A patent/HN2012002272A/es unknown
- 2012-10-24 CL CL2012002979A patent/CL2012002979A1/es unknown
- 2012-10-25 GT GT201200289A patent/GT201200289A/es unknown
- 2012-11-15 CR CR20120584A patent/CR20120584A/es unknown
- 2012-11-23 EC ECSP12012302 patent/ECSP12012302A/es unknown
- 2012-11-26 CO CO12213540A patent/CO6592042A2/es active IP Right Grant
-
2013
- 2013-08-27 HK HK13110019.1A patent/HK1182594A1/xx unknown
-
2016
- 2016-08-30 HR HRP20161107TT patent/HRP20161107T1/hr unknown
- 2016-08-31 CY CY20161100852T patent/CY1117956T1/el unknown
- 2016-09-01 SM SM201600298T patent/SMT201600298B/it unknown
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