HRP20150764T1 - Lijeäśenje tromboembolijskih poremeä†aja s rivaroksabanom - Google Patents
Lijeäśenje tromboembolijskih poremeä†aja s rivaroksabanom Download PDFInfo
- Publication number
- HRP20150764T1 HRP20150764T1 HRP20150764TT HRP20150764T HRP20150764T1 HR P20150764 T1 HRP20150764 T1 HR P20150764T1 HR P20150764T T HRP20150764T T HR P20150764TT HR P20150764 T HRP20150764 T HR P20150764T HR P20150764 T1 HRP20150764 T1 HR P20150764T1
- Authority
- HR
- Croatia
- Prior art keywords
- treatment
- oxo
- compound
- myocardial infarction
- rivaroxaban
- Prior art date
Links
- 230000009424 thromboembolic effect Effects 0.000 title claims 3
- KGFYHTZWPPHNLQ-AWEZNQCLSA-N rivaroxaban Chemical compound S1C(Cl)=CC=C1C(=O)NC[C@@H]1OC(=O)N(C=2C=CC(=CC=2)N2C(COCC2)=O)C1 KGFYHTZWPPHNLQ-AWEZNQCLSA-N 0.000 title claims 2
- 229960001148 rivaroxaban Drugs 0.000 title 1
- 206010000891 acute myocardial infarction Diseases 0.000 claims 4
- 208000006117 ST-elevation myocardial infarction Diseases 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 206010002388 Angina unstable Diseases 0.000 claims 1
- 206010051055 Deep vein thrombosis Diseases 0.000 claims 1
- 208000010378 Pulmonary Embolism Diseases 0.000 claims 1
- 206010038563 Reocclusion Diseases 0.000 claims 1
- 208000006011 Stroke Diseases 0.000 claims 1
- 208000007814 Unstable Angina Diseases 0.000 claims 1
- 206010047249 Venous thrombosis Diseases 0.000 claims 1
- 238000002399 angioplasty Methods 0.000 claims 1
- 210000004351 coronary vessel Anatomy 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 201000004332 intermediate coronary syndrome Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000036470 plasma concentration Effects 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
Claims (2)
1. Upotreba tablete s brzim oslobađanjem spoja 5-kloro-N-({(5S)-2-okso-3-[4-(3-okso-4-morfolinil)fenil]-1,3-oksazolidin-5-il}metil)-2-tiofenekarboksamida za proizvodnju lijeka za liječenje tromboembolijskog poremećaja koja se daje ne više od jednom dnevno kroz barem pet dana uzastopno, naznačena time da spoj ima poluvijek koncentracije plazme od 10 sati ili manje kada se oralno daje pacijentu koji je čovjek.
2. Upotreba prema zahtjevu 1, naznačena time da tromboembolijskog poremećaja je infarkt miokarda sa elevacijom ST-segmenta (STEMI), infarkt miokarda bez elevacije ST-segmenta (NSTEMI), nestabilna angina, ponovno začepljenje nakon angioplastike ili aortokoronarne premosnice, plućna embolija, duboka venska tromboza ili moždani udar.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05001893A EP1685841A1 (en) | 2005-01-31 | 2005-01-31 | Prevention and treatment of thromboembolic disorders |
EP06706291.9A EP1845961B1 (en) | 2005-01-31 | 2006-01-19 | Treatment of thromboembolic disorders with rivaroxaban |
PCT/EP2006/000431 WO2006079474A1 (en) | 2005-01-31 | 2006-01-19 | Prevention and treatment of thromboembolic disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20150764T1 true HRP20150764T1 (hr) | 2015-08-28 |
Family
ID=34933512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20150764TT HRP20150764T1 (hr) | 2005-01-31 | 2015-07-13 | Lijeäśenje tromboembolijskih poremeä†aja s rivaroksabanom |
Country Status (27)
Country | Link |
---|---|
US (1) | US9539218B2 (hr) |
EP (2) | EP1685841A1 (hr) |
JP (1) | JP2008528527A (hr) |
KR (1) | KR20070107009A (hr) |
CN (1) | CN101111236A (hr) |
AR (2) | AR052565A1 (hr) |
AU (1) | AU2006208613B2 (hr) |
BR (1) | BRPI0606760A2 (hr) |
CA (1) | CA2596145A1 (hr) |
CY (1) | CY1116494T1 (hr) |
DK (1) | DK1845961T3 (hr) |
ES (1) | ES2542335T3 (hr) |
HR (1) | HRP20150764T1 (hr) |
HU (1) | HUE025705T4 (hr) |
IL (1) | IL184585A0 (hr) |
MA (1) | MA29236B1 (hr) |
MX (1) | MX2007009100A (hr) |
NO (1) | NO344278B1 (hr) |
NZ (1) | NZ556765A (hr) |
PL (1) | PL1845961T3 (hr) |
PT (1) | PT1845961E (hr) |
SG (1) | SG159505A1 (hr) |
SI (1) | SI1845961T1 (hr) |
TW (1) | TWI377945B (hr) |
UA (1) | UA91355C2 (hr) |
WO (1) | WO2006079474A1 (hr) |
ZA (1) | ZA200706238B (hr) |
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DE10355461A1 (de) | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
EP1685841A1 (en) | 2005-01-31 | 2006-08-02 | Bayer Health Care Aktiengesellschaft | Prevention and treatment of thromboembolic disorders |
DE102005045518A1 (de) | 2005-09-23 | 2007-03-29 | Bayer Healthcare Ag | 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung |
SG166126A1 (en) | 2005-10-04 | 2010-11-29 | Bayer Schering Pharma Ag | Novel polymorphous form and the amorphous form of 5-chloro-n-({(5s)-2-oxo- 3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide |
DE102005047561A1 (de) | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung |
US7816355B1 (en) | 2009-04-28 | 2010-10-19 | Apotex Pharmachem Inc | Processes for the preparation of rivaroxaban and intermediates thereof |
WO2010147978A1 (en) | 2009-06-16 | 2010-12-23 | Pfizer Inc. | Dosage forms of apixaban |
EP3378854B1 (en) | 2010-01-27 | 2022-12-21 | Arena Pharmaceuticals, Inc. | Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof |
EP2538360A1 (en) * | 2011-06-16 | 2012-12-26 | Koninklijke Philips Electronics N.V. | Method of predicting a blood dilution risk value |
JP2016529279A (ja) * | 2013-08-29 | 2016-09-23 | 第一三共株式会社 | がんの治療又は予防のための剤 |
SI3310760T1 (sl) | 2015-06-22 | 2023-02-28 | Arena Pharmaceuticals, Inc. | Kristalinična L-argininska sol (R)-2-(7-(4-ciklopentil-3-(trifluorometil)benziloksi)-1,2,3,4- tetrahidrociklo-penta(b)indol-3-il)ocetne kisline za uporabo pri motnjah, povezanih z receptorjem S1P1 |
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KR20190116416A (ko) | 2017-02-16 | 2019-10-14 | 아레나 파마슈티칼스, 인크. | 원발 담즙성 담관염을 치료하기 위한 화합물 및 방법 |
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DE102005047561A1 (de) | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung |
SG166126A1 (en) | 2005-10-04 | 2010-11-29 | Bayer Schering Pharma Ag | Novel polymorphous form and the amorphous form of 5-chloro-n-({(5s)-2-oxo- 3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide |
DE102005047558A1 (de) | 2005-10-04 | 2008-02-07 | Bayer Healthcare Ag | Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen |
DE102005048824A1 (de) | 2005-10-10 | 2007-04-12 | Bayer Healthcare Ag | Behandlung und Prophylaxe von Mikroangiopathien |
DE102006034916A1 (de) | 2006-07-28 | 2008-01-31 | Bayer Healthcare Ag | Beschichtung künstlicher Oberflächen von medizinischen Hilfsmitteln und Geräten sowie Reinigung und/oder Vorbehandlung von Kathetern und anderen medizinischen Hilfsmitteln und Geräten |
DE102006051625A1 (de) | 2006-11-02 | 2008-05-08 | Bayer Materialscience Ag | Kombinationstherapie substituierter Oxazolidinone |
-
2005
- 2005-01-31 EP EP05001893A patent/EP1685841A1/en not_active Withdrawn
-
2006
- 2006-01-19 UA UAA200709807A patent/UA91355C2/ru unknown
- 2006-01-19 WO PCT/EP2006/000431 patent/WO2006079474A1/en active Application Filing
- 2006-01-19 PT PT67062919T patent/PT1845961E/pt unknown
- 2006-01-19 BR BRPI0606760-3A patent/BRPI0606760A2/pt not_active Application Discontinuation
- 2006-01-19 SI SI200631948T patent/SI1845961T1/sl unknown
- 2006-01-19 NZ NZ556765A patent/NZ556765A/en unknown
- 2006-01-19 US US11/883,218 patent/US9539218B2/en active Active
- 2006-01-19 EP EP06706291.9A patent/EP1845961B1/en active Active
- 2006-01-19 SG SG201000639-3A patent/SG159505A1/en unknown
- 2006-01-19 DK DK06706291.9T patent/DK1845961T3/en active
- 2006-01-19 HU HUE06706291A patent/HUE025705T4/hu unknown
- 2006-01-19 ES ES06706291.9T patent/ES2542335T3/es active Active
- 2006-01-19 KR KR1020077017201A patent/KR20070107009A/ko not_active Application Discontinuation
- 2006-01-19 MX MX2007009100A patent/MX2007009100A/es not_active Application Discontinuation
- 2006-01-19 JP JP2007552555A patent/JP2008528527A/ja active Pending
- 2006-01-19 CA CA002596145A patent/CA2596145A1/en not_active Abandoned
- 2006-01-19 PL PL06706291T patent/PL1845961T3/pl unknown
- 2006-01-19 AU AU2006208613A patent/AU2006208613B2/en active Active
- 2006-01-19 CN CNA200680003676XA patent/CN101111236A/zh active Pending
- 2006-01-27 TW TW095103241A patent/TWI377945B/zh active
- 2006-01-30 AR ARP060100331A patent/AR052565A1/es not_active Application Discontinuation
-
2007
- 2007-07-12 IL IL184585A patent/IL184585A0/en unknown
- 2007-07-26 MA MA30105A patent/MA29236B1/fr unknown
- 2007-07-27 ZA ZA200706238A patent/ZA200706238B/xx unknown
- 2007-08-27 NO NO20074356A patent/NO344278B1/no unknown
-
2015
- 2015-07-13 HR HRP20150764TT patent/HRP20150764T1/hr unknown
- 2015-07-15 CY CY20151100616T patent/CY1116494T1/el unknown
-
2017
- 2017-12-20 AR ARP170103610A patent/AR110413A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
JP2008528527A (ja) | 2008-07-31 |
NZ556765A (en) | 2010-11-26 |
AR052565A1 (es) | 2007-03-21 |
TW200640441A (en) | 2006-12-01 |
ZA200706238B (en) | 2008-11-26 |
IL184585A0 (en) | 2008-12-29 |
NO20074356L (no) | 2007-08-27 |
EP1845961A1 (en) | 2007-10-24 |
US9539218B2 (en) | 2017-01-10 |
DK1845961T3 (en) | 2015-07-20 |
EP1685841A1 (en) | 2006-08-02 |
US20090004265A1 (en) | 2009-01-01 |
UA91355C2 (ru) | 2010-07-26 |
HUE025705T4 (hu) | 2023-02-28 |
EP1845961B1 (en) | 2015-04-22 |
CY1116494T1 (el) | 2017-03-15 |
ES2542335T3 (es) | 2015-08-04 |
AU2006208613A1 (en) | 2006-08-03 |
PT1845961E (pt) | 2015-08-31 |
BRPI0606760A2 (pt) | 2009-07-14 |
SG159505A1 (en) | 2010-03-30 |
WO2006079474A1 (en) | 2006-08-03 |
CN101111236A (zh) | 2008-01-23 |
PL1845961T3 (pl) | 2015-09-30 |
NO344278B1 (no) | 2019-10-28 |
MX2007009100A (es) | 2007-09-13 |
TWI377945B (en) | 2012-12-01 |
SI1845961T1 (sl) | 2015-08-31 |
CA2596145A1 (en) | 2006-08-03 |
AR110413A2 (es) | 2019-03-27 |
KR20070107009A (ko) | 2007-11-06 |
MA29236B1 (fr) | 2008-02-01 |
AU2006208613B2 (en) | 2011-06-16 |
HUE025705T2 (en) | 2016-04-28 |
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