HRP20140454T1 - Pripravci i postupci inhibicije jak puta - Google Patents

Pripravci i postupci inhibicije jak puta Download PDF

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HRP20140454T1
HRP20140454T1 HRP20140454AT HRP20140454T HRP20140454T1 HR P20140454 T1 HRP20140454 T1 HR P20140454T1 HR P20140454A T HRP20140454A T HR P20140454AT HR P20140454 T HRP20140454 T HR P20140454T HR P20140454 T1 HRP20140454 T1 HR P20140454T1
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Croatia
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compound
treatment
pharmaceutical preparation
medication
production
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HRP20140454AT
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Hui Li
Thilo Heckrodt
Yan Chen
Darren John Mcmurtrie
Vanessa Taylor
Rajinder Singh
Pingyu Ding
Sambaiah Thhota
Rose Yen
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Rigel Pharmaceuticals, Inc.
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Application filed by Rigel Pharmaceuticals, Inc. filed Critical Rigel Pharmaceuticals, Inc.
Publication of HRP20140454T1 publication Critical patent/HRP20140454T1/hr

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Claims (13)

1. Spoj, naznačen time da je N2-(3,4,5-trimetil)fenil-5-metil-N4-(2-okso-2,3-dihidro-1,3-benzoksazol-5-il)-2,4-pirimidindiamin ili njegova farmaceutski prihvatljiva sol.
2. Spoj prema zahtjevu 1, naznačen time da je slobodna baza N2-(3,4,5-trimetil)fenil-5-metil-N4-(2-okso-2,3-dihidro-1,3-benzoksazol-5-il)-2,4-pirimidindiamina.
3. Farmaceutski pripravak, naznačen time da sadrži spoj prema zahtjevu 1 ili 2.
4. Spoj prema zahtjevu 1 ili 2 ili farmaceutski pripravak prema zahtjevu 3 naznačen time da je za uporabu kod liječenja bolesti, kod kojih je posrednik JAK kinaza.
5. Spoj ili farmaceutski pripravak za uporabu prema zahtjevu 4, naznačen time da je za uporabu kod liječenja odbacivanja presatka kod primatelja presatka.
6. Spoj ili farmaceutski pripravak za uporabu prema zahtjevu 4, naznačen time da je za uporabu kod liječenja autoimunih bolesti, gdje je posrednik T-stanica.
7. Spoj ili farmaceutski pripravak za uporabu prema zahtjevu 4, naznačen time da je za uporabu kod liječenja bolesti i/ili poremećaja oka.
8. Spoj ili farmaceutski pripravak za uporabu prema zahtjevu 4, naznačen time da je za uporabu kod liječenja astme.
9. Spoj prema zahtjevu 1 ili 2 ili farmaceutski pripravak prema zahtjevu 3 naznačen time da je za uporabu za proizvodnju medikamenta za liječenje bolesti, gdje je posrednik JAK kinaza.
10. Uporaba spoja ili farmaceutskog pripravka prema zahtjevu 9 naznačena time da je za proizvodnju medikamenta za liječenje odbacivanja presatka kod primatelja presatka.
11. Uporaba spoja ili farmaceutskog pripravka prema zahtjevu 9 naznačena time da je za proizvodnju medikamenta za liječenje autoimune bolesti, gdje je posrednik T-stanica.
12. Uporaba spoja ili farmaceutskog pripravka prema zahtjevu naznačena time da je za proizvodnju medikamenta za liječenje i/ili poremećaja oka.
13. Uporaba spoja ili farmaceutskog pripravka prema zahtjevu 9 naznačena time da je za proizvodnju medikamenta za liječenje astme.
HRP20140454AT 2009-01-23 2014-05-21 Pripravci i postupci inhibicije jak puta HRP20140454T1 (hr)

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