HRP20130882T1 - Proizvodi koji sadrže dekarboksilirane fenolne kiseline koje su derivati klorogene kiseline iz kave, te njihova upotreba - Google Patents
Proizvodi koji sadrže dekarboksilirane fenolne kiseline koje su derivati klorogene kiseline iz kave, te njihova upotreba Download PDFInfo
- Publication number
- HRP20130882T1 HRP20130882T1 HRP20130882AT HRP20130882T HRP20130882T1 HR P20130882 T1 HRP20130882 T1 HR P20130882T1 HR P20130882A T HRP20130882A T HR P20130882AT HR P20130882 T HRP20130882 T HR P20130882T HR P20130882 T1 HRP20130882 T1 HR P20130882T1
- Authority
- HR
- Croatia
- Prior art keywords
- coffee
- vinylveratrol
- vinylcatechol
- vinylguaiacol
- compound
- Prior art date
Links
- 235000013353 coffee beverage Nutrition 0.000 title claims 8
- 150000007965 phenolic acids Chemical class 0.000 title claims 4
- 235000001368 chlorogenic acid Nutrition 0.000 title claims 3
- 235000009048 phenolic acids Nutrition 0.000 title 1
- YOMSJEATGXXYPX-UHFFFAOYSA-N 2-methoxy-4-vinylphenol Chemical compound COC1=CC(C=C)=CC=C1O YOMSJEATGXXYPX-UHFFFAOYSA-N 0.000 claims 12
- FBTSUTGMWBDAAC-UHFFFAOYSA-N 3,4-Dihydroxystyrene Chemical compound OC1=CC=C(C=C)C=C1O FBTSUTGMWBDAAC-UHFFFAOYSA-N 0.000 claims 12
- 150000001875 compounds Chemical class 0.000 claims 9
- 238000000034 method Methods 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 7
- NJXYTXADXSRFTJ-UHFFFAOYSA-N 1,2-Dimethoxy-4-vinylbenzene Chemical compound COC1=CC=C(C=C)C=C1OC NJXYTXADXSRFTJ-UHFFFAOYSA-N 0.000 claims 6
- 235000013361 beverage Nutrition 0.000 claims 5
- 241000533293 Sesbania emerus Species 0.000 claims 4
- 235000013305 food Nutrition 0.000 claims 4
- 208000010877 cognitive disease Diseases 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 244000005700 microbiome Species 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 239000000047 product Substances 0.000 claims 2
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 claims 1
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 208000014644 Brain disease Diseases 0.000 claims 1
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 claims 1
- 206010012289 Dementia Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 208000019022 Mood disease Diseases 0.000 claims 1
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 230000010072 bone remodeling Effects 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 claims 1
- 229940074393 chlorogenic acid Drugs 0.000 claims 1
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 claims 1
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 claims 1
- 230000006999 cognitive decline Effects 0.000 claims 1
- 235000009508 confectionery Nutrition 0.000 claims 1
- 235000013365 dairy product Nutrition 0.000 claims 1
- 238000006114 decarboxylation reaction Methods 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 238000000855 fermentation Methods 0.000 claims 1
- 230000004151 fermentation Effects 0.000 claims 1
- 235000015203 fruit juice Nutrition 0.000 claims 1
- 230000006870 function Effects 0.000 claims 1
- 235000011868 grain product Nutrition 0.000 claims 1
- 230000007062 hydrolysis Effects 0.000 claims 1
- 238000006460 hydrolysis reaction Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 235000021539 instant coffee Nutrition 0.000 claims 1
- 239000004310 lactic acid Substances 0.000 claims 1
- 235000014655 lactic acid Nutrition 0.000 claims 1
- 208000002780 macular degeneration Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 208000027061 mild cognitive impairment Diseases 0.000 claims 1
- 208000015122 neurodegenerative disease Diseases 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000004845 protein aggregation Effects 0.000 claims 1
- 208000019116 sleep disease Diseases 0.000 claims 1
- 235000014214 soft drink Nutrition 0.000 claims 1
- 235000015192 vegetable juice Nutrition 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F5/00—Coffee; Coffee substitutes; Preparations thereof
- A23F5/02—Treating green coffee; Preparations produced thereby
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Mycology (AREA)
- Obesity (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Biochemistry (AREA)
Claims (13)
1. Postupak dobivanja ekstrakta kave koji sadrži spoj kojeg se bira između 4-vinilkatekola, 4-vinilgvajakola, 4-vinilveratrola, te njihovih smjesa, naznačen time što se postupak sastoji u:
a) ekstrakciji zrna kave vodom i/ili vodenom parom kako bi se dobilo ekstrakt kave; i
b) obradi ekstrakta kave radi hidrolize klorogene kiseline koja se nalazi u ekstrakt to fenolna kiselina, i to dekarboksilate the resulting fenolna kiselina.
2. Postupak u skladu s patentnim zahtjevom 1, naznačen time što se hidrolizu klorogenih kiselina i dekarboksilaciju fenolne kiseline u koraku b) provodi uz pomoć mikroorganizma.
3. Postupak u skladu s patentnim zahtjevom 2, naznačen time što je mikroorganizam bakterija mliječnokiselog vrenja.
4. Postupak u skladu s bilo kojim od patentnih zahtjeva 1-3, naznačen time što su zrna kave koja treba ekstrahirati nezrela zrna kave.
5. Ekstrakt kave, naznačen time što ukupno sadrži najmanje 0,1 mg 4-vinilkatekola, 4-vinilgvajakola i 4-vinilveratrola po gramu suhe tvari.
6. Ekstrakt kave u skladu s patentnim zahtjevom 5, naznačen time što je ekstrakt nezrelih zrna kave.
7. Postupak proizvodnje prehrambenog proizvoda ili napitka, naznačen time što se ekstrakt kave u skladu s bilo kojim od patentnih zahtjeva 5 ili 6 upotrebljava kao sastojak navedenog prehrambenog proizvoda ili napitka.
8. Postupak u skladu s patentnim zahtjevom 8, naznačen time što je prehrambeni proizvod ili napitak napitak na bazi kave, čista topljiva kava, bezalkoholno piće, prehrambeni dodatak, mliječni proizvod, žitni proizvod, proizvod od voćnog ili povrtnog soka, ili slastičarski proizvod.
9. Upotreba spoja kojeg se bira između 4-vinilkatekola, 4-vinilgvajakola, 4-vinilveratrola, te njihovih smjesa, naznačena time što je spoj namijenjen pripravi medikamenta.
10. Upotreba spoja kojeg se bira između 4-vinilkatekola, 4-vinilgvajakola, 4-vinilveratrola, te njihovih smjesa, naznačena time što je spoj namijenjen pripravi formulacije za liječenje ili sprječavanje poremećaja mozga, upale, pretilosti, raka, neurodegenerativnih poremećaja, opadanja kognitivnih funkcija, blagog poremećaja kognitivnih funkcija, demencije, poremećaja raspoloženja, depresije, poremećaja spavanja, bolesti koja uključuje agregiranje proteina, Alzheimerove bolesti, degeneracije makule ili dijabetesa.
11. Upotreba u skladu s patentnim zahtjevom 11, naznačen time što je navedena formulacija prehrambeni proizvod ili napitak.
12. Upotreba spoja kojeg se bira između 4-vinilkatekola, 4-vinilgvajakola, 4-vinilveratrola, te njihovih smjesa, naznačena time što je spoj namijenjen poticanju pregradnje kostiju.
13. Upotreba spoja kojeg se bira između 4-vinilkatekola, 4-vinilgvajakola, 4-vinilveratrola, te njihovih smjesa, naznačena time što je spoj namijenjen povećavanju antioksidativne sposobnosti in vivo kod čovjeka ili životinje i/ili kod zaštite mozga.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08155434 | 2008-04-30 | ||
| PCT/EP2009/052939 WO2009132889A1 (en) | 2008-04-30 | 2009-03-12 | Products comprising, and uses of, decarboxylated phenolic acids derived from chlorogenic acids of coffee |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20130882T1 true HRP20130882T1 (hr) | 2013-10-25 |
Family
ID=39769342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20130882AT HRP20130882T1 (hr) | 2008-04-30 | 2013-09-18 | Proizvodi koji sadrže dekarboksilirane fenolne kiseline koje su derivati klorogene kiseline iz kave, te njihova upotreba |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20110046235A1 (hr) |
| EP (1) | EP2282642B1 (hr) |
| JP (1) | JP5504254B2 (hr) |
| KR (1) | KR20110008200A (hr) |
| CN (1) | CN102014648A (hr) |
| AR (1) | AR071425A1 (hr) |
| AU (1) | AU2009242334B2 (hr) |
| BR (1) | BRPI0910839A2 (hr) |
| CA (1) | CA2723054C (hr) |
| CL (1) | CL2009001030A1 (hr) |
| CO (1) | CO6280591A2 (hr) |
| ES (1) | ES2425691T3 (hr) |
| HR (1) | HRP20130882T1 (hr) |
| MX (1) | MX2010011060A (hr) |
| MY (1) | MY161337A (hr) |
| PE (1) | PE20100129A1 (hr) |
| PL (1) | PL2282642T3 (hr) |
| PT (1) | PT2282642E (hr) |
| RU (1) | RU2010148751A (hr) |
| TW (1) | TW200944132A (hr) |
| UA (1) | UA103765C2 (hr) |
| UY (1) | UY31797A (hr) |
| WO (1) | WO2009132889A1 (hr) |
| ZA (1) | ZA201008552B (hr) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA111058C2 (uk) | 2009-12-18 | 2016-03-25 | Нестек С.А. | Спосіб одержання кавового екстракту із необсмажених зерен кави |
| MX358237B (es) * | 2010-07-30 | 2018-08-10 | Loreal Star | Uso de café verde y probiótico para regular pigmentación de la piel. |
| EP2454945A1 (en) * | 2010-11-12 | 2012-05-23 | Nestec S.A. | Methods of improving mental or physical health conditions in an individual |
| KR101060203B1 (ko) | 2011-03-16 | 2011-08-29 | 김인재 | 커피 원두의 가공 방법 및 이에 의하여 제조된 커피 원두 |
| US9034410B2 (en) * | 2011-08-22 | 2015-05-19 | Thomas J. Vella | Whole green coffee bean products and methods of production and use |
| WO2013042811A1 (ko) * | 2011-09-22 | 2013-03-28 | (주)바이오에프디엔씨 | 카페오일알파네오엔돌핀 펩타이드 유도체 및 이의 항가려움 및 항아토피 소재로의 활용 |
| EP2659782A1 (en) * | 2012-05-04 | 2013-11-06 | Nestec S.A. | Methods of improving mental or health conditions |
| JP6348511B2 (ja) * | 2012-12-28 | 2018-06-27 | ネステク ソシエテ アノニム | 発泡助剤及びその製造方法 |
| KR101584632B1 (ko) | 2013-12-11 | 2016-01-12 | 한국벡스팜제약 주식회사 | 배변 활동을 향상시키는 커피 조성물 |
| JP6981685B2 (ja) * | 2014-10-21 | 2021-12-17 | 丸善製薬株式会社 | 皮膚化粧料、頭髪化粧料および飲食品 |
| JP6666650B2 (ja) * | 2014-10-21 | 2020-03-18 | 丸善製薬株式会社 | 皮膚化粧料、頭髪化粧料および飲食品 |
| JP6709587B2 (ja) * | 2014-10-21 | 2020-06-17 | 丸善製薬株式会社 | 皮膚化粧料および頭髪化粧料 |
| JP6396760B2 (ja) * | 2014-10-31 | 2018-09-26 | 花王株式会社 | 睡眠の質改善具 |
| CN107438672B (zh) * | 2015-04-09 | 2021-09-28 | 雀巢产品有限公司 | 形成二氢阿魏酸的方法 |
| KR101661172B1 (ko) | 2015-04-13 | 2016-09-29 | 강림중공업 주식회사 | 증발가스 처리장치용 가스연소기 |
| KR101661169B1 (ko) | 2015-04-13 | 2016-09-29 | 강림중공업 주식회사 | 증발가스 처리장치용 가스연소기 |
| KR101661173B1 (ko) | 2015-04-13 | 2016-09-29 | 강림중공업 주식회사 | 냉각구조의 소형 증발가스 처리장치용 연소기 |
| KR20170032815A (ko) | 2015-09-15 | 2017-03-23 | 경희대학교 산학협력단 | 신규 유산균 및 퇴행성 뇌질환 또는 인지기능의 예방, 개선 또는 치료용 조성물 |
| JP6946039B2 (ja) * | 2016-04-08 | 2021-10-06 | 高砂香料工業株式会社 | 酢酸含有飲食品組成物 |
| JP6517968B2 (ja) * | 2018-03-12 | 2019-05-22 | 花王株式会社 | 睡眠改善剤 |
| JP6993627B2 (ja) * | 2019-01-30 | 2022-01-13 | 丸善製薬株式会社 | 皮膚化粧料、頭髪化粧料および飲食品 |
| JP6993628B2 (ja) * | 2019-01-30 | 2022-01-13 | 丸善製薬株式会社 | 皮膚化粧料、頭髪化粧料および飲食品 |
| JP7253263B2 (ja) | 2020-03-17 | 2023-04-06 | 丸善製薬株式会社 | 皮膚化粧料、頭髪化粧料および飲食品 |
| EP4167747A1 (en) * | 2020-06-17 | 2023-04-26 | Société des Produits Nestlé S.A. | Stabilization of lc-pufas by side stream product from green coffee decaffeination |
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| GB9004348D0 (en) * | 1990-02-27 | 1990-04-25 | Orion Yhtymae Oy | New use of catechol derivatives and their physiologically acceptable salts and esters |
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| WO1997022341A1 (en) * | 1995-12-21 | 1997-06-26 | Smithkline Beecham Corporation | Endothelin receptor antagonists |
| US5997929A (en) | 1997-11-03 | 1999-12-07 | Nestec S.A. | Extraction process |
| DE19832245A1 (de) | 1998-07-17 | 2000-01-20 | Heidelberger Druckmasch Ag | Verfahren zum Bedienen von Geräten in der Reproduktionstechnik |
| GB9903216D0 (en) * | 1999-02-13 | 1999-04-07 | Zylepsis Ltd | Preservative compounds,compositions and methods of making and using the same |
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| SE527555C2 (sv) * | 2003-04-04 | 2006-04-11 | Probi Ab | Anti-inflammatorisk komposition innehållande tannasproducerande Lactobacillusstammar |
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| ATE525080T1 (de) * | 2003-10-06 | 2011-10-15 | Oryza Oil & Fat Chem | Dietätische zusammensetzung |
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| EP1712137A1 (en) * | 2005-04-12 | 2006-10-18 | Nestec S.A. | Coffee product |
| JP4873444B2 (ja) * | 2005-06-03 | 2012-02-08 | 日本たばこ産業株式会社 | 血液凝固遅延剤 |
| CA2582969A1 (en) * | 2006-03-21 | 2007-09-21 | National Research Council Of Canada | Process for producing 4-vinylguaiacol by biodecarboxylation of ferulic acid |
| CN101057678B (zh) * | 2007-06-13 | 2010-09-01 | 深圳市金沙江投资有限公司 | 一种含有天然植物提取物或单体的组合物 |
| JP5162212B2 (ja) * | 2007-11-19 | 2013-03-13 | 丸善製薬株式会社 | 新規乳酸菌、乳酸菌組成物及び植物エキス、並びに、植物エキス及び低分子ポリフェノールの製造方法 |
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- 2009-03-12 CN CN2009801155011A patent/CN102014648A/zh active Pending
- 2009-03-12 EP EP09737933.3A patent/EP2282642B1/en active Active
- 2009-03-12 MY MYPI2010004395A patent/MY161337A/en unknown
- 2009-03-12 KR KR1020107024428A patent/KR20110008200A/ko not_active Application Discontinuation
- 2009-03-12 US US12/990,587 patent/US20110046235A1/en not_active Abandoned
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- 2009-03-12 PL PL09737933T patent/PL2282642T3/pl unknown
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- 2009-03-12 RU RU2010148751/10A patent/RU2010148751A/ru not_active Application Discontinuation
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- 2009-03-12 UA UAA201012995A patent/UA103765C2/uk unknown
- 2009-03-12 WO PCT/EP2009/052939 patent/WO2009132889A1/en active Application Filing
- 2009-03-26 TW TW098109987A patent/TW200944132A/zh unknown
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| CA2723054A1 (en) | 2009-11-05 |
| PL2282642T3 (pl) | 2013-12-31 |
| EP2282642A1 (en) | 2011-02-16 |
| EP2282642B1 (en) | 2013-07-24 |
| AU2009242334B2 (en) | 2014-05-01 |
| WO2009132889A1 (en) | 2009-11-05 |
| MX2010011060A (es) | 2010-11-22 |
| BRPI0910839A2 (pt) | 2015-07-28 |
| ZA201008552B (en) | 2012-05-30 |
| PE20100129A1 (es) | 2010-03-02 |
| KR20110008200A (ko) | 2011-01-26 |
| CO6280591A2 (es) | 2011-05-20 |
| MY161337A (en) | 2017-04-14 |
| PT2282642E (pt) | 2013-08-27 |
| UY31797A (es) | 2009-11-10 |
| RU2010148751A (ru) | 2012-06-10 |
| AU2009242334A1 (en) | 2009-11-05 |
| CN102014648A (zh) | 2011-04-13 |
| TW200944132A (en) | 2009-11-01 |
| CA2723054C (en) | 2016-12-13 |
| ES2425691T3 (es) | 2013-10-16 |
| JP2011518570A (ja) | 2011-06-30 |
| UA103765C2 (uk) | 2013-11-25 |
| AR071425A1 (es) | 2010-06-16 |
| US20110046235A1 (en) | 2011-02-24 |
| JP5504254B2 (ja) | 2014-05-28 |
| CL2009001030A1 (es) | 2010-06-11 |
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