HRP20110570T1 - Amidi diazabicikloalkana selektivni na podvrstu nikotinskih acetilkolinskih receptora - Google Patents

Amidi diazabicikloalkana selektivni na podvrstu nikotinskih acetilkolinskih receptora Download PDF

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Publication number
HRP20110570T1
HRP20110570T1 HR20110570T HRP20110570T HRP20110570T1 HR P20110570 T1 HRP20110570 T1 HR P20110570T1 HR 20110570 T HR20110570 T HR 20110570T HR P20110570 T HRP20110570 T HR P20110570T HR P20110570 T1 HRP20110570 T1 HR P20110570T1
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Croatia
Prior art keywords
disorder
compound
dementia
disorders
composition
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HR20110570T
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English (en)
Croatian (hr)
Inventor
Mazurov Anatoly
Miao Lan
Xiao Yun-De
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Targacept
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Publication of HRP20110570T1 publication Critical patent/HRP20110570T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HR20110570T 2006-11-02 2007-11-01 Amidi diazabicikloalkana selektivni na podvrstu nikotinskih acetilkolinskih receptora HRP20110570T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85607906P 2006-11-02 2006-11-02
PCT/US2007/083330 WO2008057938A1 (en) 2006-11-02 2007-11-01 Nicotinic acetylcholine receptorsub-type selective amides of diazabicycloalkanes

Publications (1)

Publication Number Publication Date
HRP20110570T1 true HRP20110570T1 (hr) 2011-09-30

Family

ID=39233054

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20110570T HRP20110570T1 (hr) 2006-11-02 2007-11-01 Amidi diazabicikloalkana selektivni na podvrstu nikotinskih acetilkolinskih receptora

Country Status (32)

Country Link
US (6) US8114889B2 (enExample)
EP (2) EP2094703B1 (enExample)
JP (2) JP5539723B2 (enExample)
KR (2) KR101415705B1 (enExample)
CN (4) CN102942569B (enExample)
AR (2) AR063451A1 (enExample)
AT (2) ATE545646T1 (enExample)
AU (2) AU2007317433B2 (enExample)
BR (2) BRPI0717930A2 (enExample)
CA (1) CA2663925C (enExample)
CL (1) CL2007003155A1 (enExample)
CO (1) CO6180435A2 (enExample)
CY (1) CY1112374T1 (enExample)
DK (1) DK2094703T3 (enExample)
ES (2) ES2395212T3 (enExample)
HR (1) HRP20110570T1 (enExample)
IL (2) IL197618A (enExample)
MX (1) MX2009004801A (enExample)
MY (2) MY145602A (enExample)
NO (1) NO20091251L (enExample)
NZ (2) NZ575557A (enExample)
PE (2) PE20110671A1 (enExample)
PL (1) PL2094703T3 (enExample)
PT (1) PT2094703E (enExample)
RS (1) RS51834B (enExample)
RU (2) RU2448969C2 (enExample)
SA (1) SA07280584B1 (enExample)
SI (1) SI2094703T1 (enExample)
TW (3) TWI454262B (enExample)
UA (2) UA106718C2 (enExample)
UY (1) UY30686A1 (enExample)
WO (1) WO2008057938A1 (enExample)

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BRPI0717930A2 (pt) 2011-05-10
TWI454262B (zh) 2014-10-01
MY145602A (en) 2012-03-15
US20120289572A1 (en) 2012-11-15
US8921410B2 (en) 2014-12-30
EP2284171A1 (en) 2011-02-16
CN102838605B (zh) 2017-04-26
BRPI0722387A2 (pt) 2023-02-23
CN102020646A (zh) 2011-04-20
MX2009004801A (es) 2009-07-31
EP2094703B1 (en) 2011-05-11
US20100173932A1 (en) 2010-07-08
UA98944C2 (ru) 2012-07-10
KR20100124356A (ko) 2010-11-26
IL197618A0 (en) 2009-12-24
US9580434B2 (en) 2017-02-28
TWI405763B (zh) 2013-08-21
CO6180435A2 (es) 2010-07-19
US8859609B2 (en) 2014-10-14
CA2663925A1 (en) 2008-05-15
CL2007003155A1 (es) 2008-05-16
CN102942569B (zh) 2015-10-28
TWI404532B (zh) 2013-08-11
JP5739398B2 (ja) 2015-06-24
IL197618A (en) 2013-09-30
CA2663925C (en) 2015-04-21
ATE509022T1 (de) 2011-05-15
DK2094703T3 (da) 2011-08-29
RU2517693C2 (ru) 2014-05-27
WO2008057938A1 (en) 2008-05-15
NZ575557A (en) 2011-01-28
EP2094703A1 (en) 2009-09-02
JP2013056919A (ja) 2013-03-28
JP5539723B2 (ja) 2014-07-02
AU2010219323B2 (en) 2012-05-03
CN101528745A (zh) 2009-09-09
SI2094703T1 (sl) 2011-07-29
CN102942569A (zh) 2013-02-27
US20160039833A1 (en) 2016-02-11
RU2448969C2 (ru) 2012-04-27
IL209026A0 (en) 2011-01-31
ES2395157T3 (es) 2013-02-08
CY1112374T1 (el) 2015-12-09
RS51834B (sr) 2012-02-29
NO20091251L (no) 2009-05-28
HK1133260A1 (en) 2010-03-19
AR063451A1 (es) 2009-01-28
RU2009120674A (ru) 2010-12-10
TW201114424A (en) 2011-05-01
US20100081683A1 (en) 2010-04-01
US20150080576A1 (en) 2015-03-19
MY156730A (en) 2016-03-15
PE20081441A1 (es) 2008-10-30
ES2395212T3 (es) 2013-02-11
HK1149751A1 (en) 2011-10-14
KR20090074051A (ko) 2009-07-03
ATE545646T1 (de) 2012-03-15
TW200826935A (en) 2008-07-01
AU2007317433A1 (en) 2008-05-15
JP2010509230A (ja) 2010-03-25
AR079840A2 (es) 2012-02-22
KR101415705B1 (ko) 2014-07-04
US8268860B2 (en) 2012-09-18
SA07280584B1 (ar) 2010-11-02
AU2007317433B2 (en) 2012-05-10
PE20110671A1 (es) 2011-10-20
UA106718C2 (uk) 2014-10-10
CN101528745B (zh) 2011-09-14
AU2010219323A1 (en) 2010-09-30
CN102020646B (zh) 2013-11-13
UY30686A1 (es) 2009-08-03
RU2009138600A (ru) 2011-04-27
CN102838605A (zh) 2012-12-26
TW201305176A (zh) 2013-02-01
NZ587847A (en) 2011-09-30
US8114889B2 (en) 2012-02-14
PL2094703T3 (pl) 2011-10-31
PT2094703E (pt) 2011-07-22
EP2284171B1 (en) 2012-02-15
IL209026A (en) 2014-03-31
US20130005789A1 (en) 2013-01-03

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