HRP20100153T1 - Antagonisti kemokin receptora - Google Patents

Antagonisti kemokin receptora Download PDF

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Publication number
HRP20100153T1
HRP20100153T1 HR20100153T HRP20100153T HRP20100153T1 HR P20100153 T1 HRP20100153 T1 HR P20100153T1 HR 20100153 T HR20100153 T HR 20100153T HR P20100153 T HRP20100153 T HR P20100153T HR P20100153 T1 HRP20100153 T1 HR P20100153T1
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Croatia
Prior art keywords
piperidin
indole
amide
carboxylic acid
ethyl
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HR20100153T
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English (en)
Croatian (hr)
Inventor
Hersperger Ren�
Janser Philipp
Pfenninger Emil
Juerg Wuethrich Hans
Miltz Wolfgang
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Novartis Ag
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32011733&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20100153(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HRP20100153T1 publication Critical patent/HRP20100153T1/hr

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems

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  • Orthopedic Medicine & Surgery (AREA)
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  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
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  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Otolaryngology (AREA)
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  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Heart & Thoracic Surgery (AREA)
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HR20100153T 2004-02-11 2010-03-17 Antagonisti kemokin receptora HRP20100153T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0403038.3A GB0403038D0 (en) 2004-02-11 2004-02-11 Organic compounds
PCT/EP2005/001362 WO2005077932A2 (en) 2004-02-11 2005-02-10 Chemokine receptor antagonists

Publications (1)

Publication Number Publication Date
HRP20100153T1 true HRP20100153T1 (hr) 2010-06-30

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ID=32011733

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20100153T HRP20100153T1 (hr) 2004-02-11 2010-03-17 Antagonisti kemokin receptora

Country Status (34)

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US (2) US7858781B2 (zh)
EP (1) EP1720859B1 (zh)
JP (1) JP4550072B2 (zh)
KR (1) KR100883236B1 (zh)
CN (2) CN102391251A (zh)
AR (1) AR047545A1 (zh)
AT (1) ATE452886T1 (zh)
AU (1) AU2005212510B2 (zh)
BR (1) BRPI0507617A (zh)
CA (1) CA2554642C (zh)
CY (1) CY1109936T1 (zh)
DE (1) DE602005018456D1 (zh)
DK (1) DK1720859T3 (zh)
EC (1) ECSP066753A (zh)
ES (1) ES2338898T3 (zh)
GB (1) GB0403038D0 (zh)
HK (1) HK1098464A1 (zh)
HR (1) HRP20100153T1 (zh)
IL (1) IL177183A (zh)
MA (1) MA28432B1 (zh)
MY (1) MY142444A (zh)
NO (1) NO20064077L (zh)
NZ (1) NZ548741A (zh)
PE (1) PE20051169A1 (zh)
PL (1) PL1720859T3 (zh)
PT (1) PT1720859E (zh)
RS (1) RS51203B (zh)
RU (1) RU2395506C2 (zh)
SG (1) SG164288A1 (zh)
SI (1) SI1720859T1 (zh)
TN (1) TNSN06255A1 (zh)
TW (1) TWI346553B (zh)
WO (1) WO2005077932A2 (zh)
ZA (1) ZA200606180B (zh)

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AR065369A1 (es) * 2007-02-19 2009-06-03 Novartis Ag Derivados de ciclohexil - amida del acido aril- carboxilico
WO2009158375A1 (en) * 2008-06-25 2009-12-30 Abbott Laboratories Aza-cylic indole- 2 -carboxamides and methods of use thereof
US8273900B2 (en) 2008-08-07 2012-09-25 Novartis Ag Organic compounds
PL2513115T3 (pl) 2009-12-18 2014-04-30 Basilea Pharmaceutica Ag Antybiotyki tricykliczne
AP3649A (en) 2011-02-23 2016-03-18 Lupin Ltd Heteroaryl derivatives as alpha7 nachr modulators
US20140005174A1 (en) * 2011-03-17 2014-01-02 Anilkumar G. Nair Indole derivatives useful as ccr2 antagonists
JP2014517019A (ja) 2011-06-17 2014-07-17 バジリア ファルマスーチカ アーゲー 三環式抗生物質
US8846656B2 (en) 2011-07-22 2014-09-30 Novartis Ag Tetrahydropyrido-pyridine and tetrahydropyrido-pyrimidine compounds and use thereof as C5a receptor modulators
CN102952062B (zh) * 2011-08-12 2016-06-08 中国医学科学院医药生物技术研究所 取代苯并杂环类化合物及其制备方法和应用
CA2860323C (en) 2011-12-28 2022-03-08 The Regents Of The University Of California Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation
ES2790358T3 (es) 2011-12-28 2020-10-27 Global Blood Therapeutics Inc Compuestos de heteroaril aldehído sustituido y métodos para su uso en el aumento de la oxigenación tisular
AU2013229177B2 (en) 2012-03-06 2017-03-23 Lupin Limited Thiazole derivatives as alpha 7 nAChR modulators
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10100043B2 (en) 2013-03-15 2018-10-16 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
AU2014237348C1 (en) 2013-03-15 2019-02-07 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
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