PL2513115T3 - Antybiotyki tricykliczne - Google Patents

Antybiotyki tricykliczne

Info

Publication number
PL2513115T3
PL2513115T3 PL10793255T PL10793255T PL2513115T3 PL 2513115 T3 PL2513115 T3 PL 2513115T3 PL 10793255 T PL10793255 T PL 10793255T PL 10793255 T PL10793255 T PL 10793255T PL 2513115 T3 PL2513115 T3 PL 2513115T3
Authority
PL
Poland
Prior art keywords
tricyclic
antibiotics
tricyclic antibiotics
Prior art date
Application number
PL10793255T
Other languages
English (en)
Inventor
Bérangère Gaucher
Franck Hubert Danel
Xiaohu Tang
Tong Xie
Lin Xu
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Publication of PL2513115T3 publication Critical patent/PL2513115T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems
    • C07D491/147Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PL10793255T 2009-12-18 2010-12-17 Antybiotyki tricykliczne PL2513115T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09179956 2009-12-18
PCT/EP2010/070043 WO2011073378A1 (en) 2009-12-18 2010-12-17 Tricyclic antibiotics
EP10793255.0A EP2513115B1 (en) 2009-12-18 2010-12-17 Tricyclic antibiotics

Publications (1)

Publication Number Publication Date
PL2513115T3 true PL2513115T3 (pl) 2014-04-30

Family

ID=41716611

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10793255T PL2513115T3 (pl) 2009-12-18 2010-12-17 Antybiotyki tricykliczne

Country Status (19)

Country Link
US (2) US8927541B2 (pl)
EP (1) EP2513115B1 (pl)
JP (1) JP5697685B2 (pl)
KR (1) KR101891834B1 (pl)
CN (1) CN102666548B (pl)
AU (1) AU2010332767B2 (pl)
BR (1) BR112012014519A8 (pl)
CA (1) CA2780006A1 (pl)
CY (1) CY1114802T1 (pl)
DK (1) DK2513115T3 (pl)
ES (1) ES2441348T3 (pl)
HR (1) HRP20140005T1 (pl)
MX (1) MX2012006094A (pl)
PL (1) PL2513115T3 (pl)
PT (1) PT2513115E (pl)
SI (1) SI2513115T1 (pl)
TW (1) TWI487709B (pl)
WO (1) WO2011073378A1 (pl)
ZA (1) ZA201203540B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2596369T3 (es) * 2011-06-17 2017-01-09 Basilea Pharmaceutica Ag Antibióticos N-heterotricíclicos
TWI598099B (zh) * 2012-04-30 2017-09-11 健生科學愛爾蘭無限公司 新化合物及其新用途
GB201406486D0 (en) * 2014-04-10 2014-05-28 Redx Pharma Ltd Antibacterial compounds
US10344023B2 (en) * 2014-12-23 2019-07-09 Proteostasis Therapeutics, Inc. Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis
CN110177796B (zh) * 2017-01-06 2022-04-08 阿斯克里斯有限公司 喹啉酮衍生物及其用于预防或治疗变应性疾病的药物组合物
US20250214980A1 (en) 2022-03-14 2025-07-03 Slap Pharmaceuticals Llc Multicyclic compounds

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430148A (en) 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
JP4242643B2 (ja) 2000-10-26 2009-03-25 スミスクライン ビーチャム ピー エル シー ベンズオキサジノン誘導体、その製造および使用
TW200406413A (en) 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
TW200427688A (en) 2002-12-18 2004-12-16 Glaxo Group Ltd Antibacterial agents
US7037909B2 (en) 2003-07-02 2006-05-02 Sugen, Inc. Tetracyclic compounds as c-Met inhibitors
AU2004289690A1 (en) 2003-11-10 2005-05-26 Schering Aktiengesellschaft Benzylether amine compounds useful as CCR-5 antagonists
GB0403038D0 (en) 2004-02-11 2004-03-17 Novartis Ag Organic compounds
EP1773831A1 (en) * 2004-07-08 2007-04-18 Glaxo Group Limited Antibacterial agents
DE102004041163A1 (de) 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
WO2006038734A1 (en) 2004-10-08 2006-04-13 Astellas Pharma Inc. Pyridazinone derivatives cytokines inhibitors
TW200615273A (en) * 2004-11-10 2006-05-16 Nicholas Piramal India Ltd Fused tricyclic compounds as inhibitors of tumor necrosis factor-alpha
US7842810B2 (en) 2005-03-31 2010-11-30 Janssen Pharmaceutica, Nv Bicyclic pyrazole compounds as antibacterial agents
WO2007052843A1 (ja) 2005-11-04 2007-05-10 Takeda Pharmaceutical Company Limited 複素環アミド化合物およびその用途
EP1996563B1 (en) 2006-02-13 2012-03-21 F. Hoffmann-La Roche AG Heterobicyclic sulfonamide derivatives for the treatment of diabetes
GB0613208D0 (en) 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
GB0707708D0 (en) 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
WO2009012647A1 (fr) 2007-07-20 2009-01-29 Shanghai Hengrui Pharmaceutical Co., Ltd. Procédés de préparation de dérivés de quinazoline et leurs utilisations pharmaceutiques
WO2009125809A1 (ja) 2008-04-11 2009-10-15 第一三共株式会社 ピペリジン誘導体
WO2009125808A1 (ja) * 2008-04-11 2009-10-15 第一三共株式会社 アミノシクロヘキシル誘導体
TW200944529A (en) 2008-04-15 2009-11-01 Actelion Pharmaceuticals Ltd Tricyclic antibiotics
DE102008028996B4 (de) 2008-06-20 2011-06-09 Technische Universität Braunschweig Verfahren zur Nachbehandlung einer Schweißverbindung
BRPI0916571A2 (pt) 2008-08-04 2015-11-10 Actelion Pharmaceuticals Ltd composto derivado de alquilaminometiloxazolidinona tricíclo, medicamento e composição farmacêutica que o contém e uso do composto

Also Published As

Publication number Publication date
EP2513115B1 (en) 2013-10-09
HK1174026A1 (en) 2013-05-31
MX2012006094A (es) 2012-06-19
CN102666548A (zh) 2012-09-12
KR20120101711A (ko) 2012-09-14
JP2013514331A (ja) 2013-04-25
EP2513115A1 (en) 2012-10-24
AU2010332767A1 (en) 2012-05-24
KR101891834B1 (ko) 2018-09-28
TW201132645A (en) 2011-10-01
WO2011073378A1 (en) 2011-06-23
DK2513115T3 (da) 2014-01-13
TWI487709B (zh) 2015-06-11
PT2513115E (pt) 2013-12-19
CA2780006A1 (en) 2011-06-23
US9120822B2 (en) 2015-09-01
CN102666548B (zh) 2015-07-15
US8927541B2 (en) 2015-01-06
BR112012014519A8 (pt) 2017-12-26
ZA201203540B (en) 2013-01-30
JP5697685B2 (ja) 2015-04-08
BR112012014519A2 (pt) 2016-08-16
SI2513115T1 (sl) 2014-02-28
US20150072975A1 (en) 2015-03-12
CY1114802T1 (el) 2016-12-14
ES2441348T3 (es) 2014-02-04
AU2010332767B2 (en) 2014-04-24
HRP20140005T1 (hr) 2014-01-31
US20120245345A1 (en) 2012-09-27

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