HRP20090419T1 - Novi indeno[2,1a]indeni i izoindol[2,1-a]indoli - Google Patents
Novi indeno[2,1a]indeni i izoindol[2,1-a]indoli Download PDFInfo
- Publication number
- HRP20090419T1 HRP20090419T1 HR20090419T HRP20090419T HRP20090419T1 HR P20090419 T1 HRP20090419 T1 HR P20090419T1 HR 20090419 T HR20090419 T HR 20090419T HR P20090419 T HRP20090419 T HR P20090419T HR P20090419 T1 HRP20090419 T1 HR P20090419T1
- Authority
- HR
- Croatia
- Prior art keywords
- indeno
- indene
- thia
- aza
- dioxide
- Prior art date
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- VHMICKWLTGFITH-UHFFFAOYSA-N 2H-isoindole Chemical compound C1=CC=CC2=CNC=C21 VHMICKWLTGFITH-UHFFFAOYSA-N 0.000 title 1
- QKDLQFSLLCQTOH-UHFFFAOYSA-N Trichodonin Natural products C1C(O)C2C3(COC(=O)C)C(C=O)C(C)(C)CCC3OC(=O)C22C(=O)C(=C)C1C2 QKDLQFSLLCQTOH-UHFFFAOYSA-N 0.000 title 1
- 150000002469 indenes Chemical class 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 17
- 238000000034 method Methods 0.000 claims abstract 6
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- JJUQRPHMJPHFBH-UHFFFAOYSA-N 6h-isoindolo[2,1-a]indole Chemical class C1=CC=C2N3CC4=CC=CC=C4C3=CC2=C1 JJUQRPHMJPHFBH-UHFFFAOYSA-N 0.000 claims abstract 2
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- 125000006273 (C1-C3) alkyl group Chemical group 0.000 claims 4
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- 208000022821 personality disease Diseases 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 229940002612 prodrug Drugs 0.000 claims 1
- 239000000651 prodrug Substances 0.000 claims 1
- 125000006239 protecting group Chemical group 0.000 claims 1
- 201000000980 schizophrenia Diseases 0.000 claims 1
- 208000020431 spinal cord injury Diseases 0.000 claims 1
- 230000035882 stress Effects 0.000 claims 1
- 208000011117 substance-related disease Diseases 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Psychology (AREA)
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- Endocrinology (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Reproductive Health (AREA)
- Otolaryngology (AREA)
- Nutrition Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN5CH2004 | 2004-01-02 | ||
| PCT/IN2004/000430 WO2005066184A1 (fr) | 2004-01-02 | 2004-12-30 | Nouveaux indeno[2,1a]indenes et isoindol[2,1-a]indoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20090419T1 true HRP20090419T1 (hr) | 2009-09-30 |
Family
ID=34746651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20090419T HRP20090419T1 (hr) | 2004-01-02 | 2009-07-29 | Novi indeno[2,1a]indeni i izoindol[2,1-a]indoli |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7388024B2 (fr) |
| EP (1) | EP1704154B1 (fr) |
| JP (1) | JP4886522B2 (fr) |
| KR (1) | KR101049868B1 (fr) |
| CN (1) | CN1918173B (fr) |
| AT (1) | ATE430752T1 (fr) |
| AU (1) | AU2004312229B2 (fr) |
| BR (1) | BRPI0417895B8 (fr) |
| CA (1) | CA2552106C (fr) |
| CY (1) | CY1109278T1 (fr) |
| DE (1) | DE602004021031D1 (fr) |
| DK (1) | DK1704154T3 (fr) |
| EA (1) | EA010406B1 (fr) |
| ES (1) | ES2326658T3 (fr) |
| HK (1) | HK1097548A1 (fr) |
| HR (1) | HRP20090419T1 (fr) |
| MX (1) | MXPA06007415A (fr) |
| NO (1) | NO335838B1 (fr) |
| NZ (1) | NZ548743A (fr) |
| PL (1) | PL1704154T3 (fr) |
| PT (1) | PT1704154E (fr) |
| RS (1) | RS50824B (fr) |
| SI (1) | SI1704154T1 (fr) |
| WO (1) | WO2005066184A1 (fr) |
| ZA (1) | ZA200604748B (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5696136B2 (ja) * | 2009-04-23 | 2015-04-08 | アッヴィ・インコーポレイテッド | ５−ｈｔ受容体調節物質およびその使用方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5994352A (en) * | 1998-11-13 | 1999-11-30 | Pfizer Inc. | 5-arylindole derivatives |
| EP1355904B1 (fr) * | 2000-12-22 | 2007-08-01 | Wyeth | Composes heterocyclylindazole et azaindazole utilises en tant que ligands 5-hydroxytryptamine-6 |
| BR0206595A (pt) * | 2001-01-30 | 2004-07-13 | Lilly Co Eli | Composto, composição farmacêutica, e uso de um composto |
| WO2003035061A1 (fr) * | 2001-10-23 | 2003-05-01 | Biovitrum Ab | Utilisation de derives d'indole et d'indoline pour le traitement de l'obesite ou la reduction de l'apport alimentaire |
| ES2187300B1 (es) * | 2001-11-14 | 2004-06-16 | Laboratorios Del Dr. Esteve, S.A. | Derivados de sulfonamidas, su preparacion y su aplicacion como medicamentos. |
| DE60213856T2 (de) * | 2001-12-20 | 2007-09-13 | Wyeth | Indolylalkylamin-derivate als 5-hydroxytryptamin-6 liganden |
| US20050255529A1 (en) | 2002-02-01 | 2005-11-17 | Stefan Golz | Diagnostics and therapeutics for diseases associated with a new human 5-ht6 receptor |
| WO2003066056A1 (fr) | 2002-02-05 | 2003-08-14 | Glaxo Group Limited | Technique de stimulation de la croissance neuronale |
| EP1537113B9 (fr) * | 2002-06-21 | 2010-05-26 | Suven Life Sciences Limited | Arylalkyl indoles a affinite de recepteur de la serotonine utilises comme agents therapeutiques, leur procede de preparation et compositions pharmaceutiques contenant lesdits indoles |
| BRPI0312174B1 (pt) * | 2002-06-21 | 2018-10-09 | Suven Life Sciences Ltd | composto, composição farmacêutica, uso de um composto, processo para a preparação de um composto, novo intermediário e processo para a preparação de um novo intermediário |
| AU2003249582B2 (en) * | 2002-06-21 | 2006-08-03 | Suven Life Sciences Limited | Tetracyclic arylsulfonyl indoles having serotonin receptor affinity |
| AU2003292508A1 (en) | 2002-11-28 | 2004-06-18 | Suven Life Sciences Limited | N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands |
| JP4559230B2 (ja) | 2002-11-28 | 2010-10-06 | スベン ライフ サイエンシズ リミティド | セロトニン受容体に対する親和性を有する新規ｎ−アリールスルホニル−３−置換されたインドール、その調製方法、それを含有する医薬組成物 |
| CN102249981A (zh) | 2002-11-28 | 2011-11-23 | 苏文生命科学有限公司 | N-芳基磺酰基-3-氨基烷氧基吲哚 |
| KR100739987B1 (ko) | 2002-12-18 | 2007-07-16 | 수벤 라이프 사이언시스 리미티드 | 세로토닌 수용체 친화력을 가지는 테트라사이클릭 3-치환인돌 |
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2004
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- 2004-12-30 RS RSP-2009/0329A patent/RS50824B/sr unknown
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- 2004-12-30 WO PCT/IN2004/000430 patent/WO2005066184A1/fr active Application Filing
- 2004-12-30 PL PL04806777T patent/PL1704154T3/pl unknown
- 2004-12-30 DK DK04806777T patent/DK1704154T3/da active
- 2004-12-30 NZ NZ548743A patent/NZ548743A/xx not_active IP Right Cessation
- 2004-12-30 CN CN2004800417654A patent/CN1918173B/zh not_active Expired - Fee Related
- 2004-12-30 BR BRPI0417895A patent/BRPI0417895B8/pt not_active IP Right Cessation
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- 2004-12-30 MX MXPA06007415A patent/MXPA06007415A/es active IP Right Grant
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2009
- 2009-07-29 HR HR20090419T patent/HRP20090419T1/hr unknown
- 2009-08-03 CY CY20091100812T patent/CY1109278T1/el unknown
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