HRP20050903B1 - Intravenska injekcija ne-neurotoksiäśnih aktivatora plazminogena za tretman kapi - Google Patents

Intravenska injekcija ne-neurotoksiäśnih aktivatora plazminogena za tretman kapi

Info

Publication number
HRP20050903B1
HRP20050903B1 HRP20050903AA HRP20050903A HRP20050903B1 HR P20050903 B1 HRP20050903 B1 HR P20050903B1 HR P20050903A A HRP20050903A A HR P20050903AA HR P20050903 A HRP20050903 A HR P20050903A HR P20050903 B1 HRP20050903 B1 HR P20050903B1
Authority
HR
Croatia
Prior art keywords
plasminogen
intravenous injection
treating cerebral
cerebral stroke
neurotoxic
Prior art date
Application number
HRP20050903AA
Other languages
English (en)
Croatian (hr)
Inventor
Mariola Söhngen
Wolfgang Söhngen
Wolf-Dieter Schleuning
Robert Medcalf
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2003/004729 external-priority patent/WO2004096267A1/de
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of HRP20050903A2 publication Critical patent/HRP20050903A2/xx
Publication of HRP20050903B1 publication Critical patent/HRP20050903B1/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49Urokinase; Tissue plasminogen activator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • A61K38/58Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HRP20050903AA 2003-05-02 2004-04-30 Intravenska injekcija ne-neurotoksiäśnih aktivatora plazminogena za tretman kapi HRP20050903B1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/EP03/04608 2003-05-02
PCT/EP2003/004729 WO2004096267A1 (de) 2003-05-02 2003-05-06 Intravenöse injektion nicht-neurotoxischer plasminogen-aktivatoren zur behandlung von schlaganfall
PCT/EP2004/004626 WO2004096268A2 (de) 2003-05-02 2004-04-30 Intravenöse injektion nicht-neurotoxischer plasminogen-aktivatoren zur behandlung von schlaganfall

Publications (2)

Publication Number Publication Date
HRP20050903A2 HRP20050903A2 (en) 2006-08-31
HRP20050903B1 true HRP20050903B1 (hr) 2013-11-22

Family

ID=35610451

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20050903AA HRP20050903B1 (hr) 2003-05-02 2004-04-30 Intravenska injekcija ne-neurotoksiäśnih aktivatora plazminogena za tretman kapi

Country Status (10)

Country Link
EP (1) EP1622639B1 (enExample)
JP (1) JP2006525270A (enExample)
KR (1) KR101212631B1 (enExample)
BR (1) BRPI0409865A (enExample)
CA (1) CA2524573A1 (enExample)
HR (1) HRP20050903B1 (enExample)
NO (1) NO337485B1 (enExample)
NZ (1) NZ543367A (enExample)
PL (1) PL1622639T3 (enExample)
WO (1) WO2004096268A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10153601A1 (de) 2001-11-02 2003-05-22 Paion Gmbh DSPA zur Behandlung von Schlaganfall
US7759506B2 (en) 2002-02-25 2010-07-20 Diffusion Pharmaceuticals Llc Bipolar trans carotenoid salts and their uses
DE10342518A1 (de) * 2003-09-12 2005-05-12 Paion Gmbh Plasminogen-Aktivatoren mit verringerter Lysin-Bindungskapazität
EA017982B1 (ru) 2005-02-24 2013-04-30 ДИФФЬЮЖН ФАРМАСЬЮТИКАЛЗ ЭлЭлСи Фармацевтическая композиция на основе транскаротиноидов и способы лечения опухоли
EP1897554A1 (en) * 2006-08-25 2008-03-12 PAION Deutschland GmbH Method for the manufacture of a medicament for treating hemorrhagic stroke
WO2008022801A1 (en) * 2006-08-25 2008-02-28 Paion Deutschland Gmbh Method for the manufacture of a medicament for treating hemorrhagic stroke
BRPI0810647A2 (pt) 2007-04-13 2014-11-04 Diffusion Pharmaceuticals Llc " uso de trans carotenóides bipolares como um pré-tratamento e no tratamento de doença vascular periférica ".
DK2440230T3 (da) 2009-06-10 2021-01-18 Nono Inc Behandlingsregimener til behandling af neurologisk sygdom
EP3539542B1 (en) 2009-06-22 2023-04-19 Diffusion Pharmaceuticals LLC Diffusion enhancing compounds and their use with a thrombolytic
US8652476B2 (en) 2009-07-27 2014-02-18 Niigata University Pharmaceutical composition for treating ischemic events
JP5823671B2 (ja) * 2009-07-27 2015-11-25 国立大学法人 新潟大学 免疫製剤を含む脳梗塞治療用医薬品組成物
JP5823672B2 (ja) * 2009-07-27 2015-11-25 国立大学法人 新潟大学 受容体シグナル伝達阻害剤を含む脳梗塞治療用医薬品組成物
ES2654945T3 (es) 2010-06-02 2018-02-15 Diffusion Pharmaceuticals Llc Formulaciones orales de carotenoides trans bipolares
AU2012274910B2 (en) 2011-06-24 2017-05-11 Nono, Inc. Combination therapy with PSD-95 inhibitor for ischemia
US9241970B2 (en) 2011-12-13 2016-01-26 Nono Inc. Therapy for subarachnoid hemorrhage and ischemia
EP3432929A4 (en) 2016-03-24 2019-11-27 Diffusion Pharmaceuticals LLC USE OF BIPOLAR TRANSCAROTINOIDS WITH CHEMOTHERAPY AND RADIOTHERAPY FOR THE TREATMENT OF CANCER
US10617756B2 (en) 2017-01-05 2020-04-14 Shimojani, LLC Drug regimen for treatment of cerebral ischemia

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0352119A2 (en) * 1988-07-20 1990-01-24 Schering Aktiengesellschaft Vampire bat salivary plasminogen activators
WO1991005048A1 (en) * 1989-10-03 1991-04-18 Stichting Centraal Laboratorium Van De Bloedtransfusiedienst Van Het Nederlandse Rode Kruis Mutants of the human plasminogen activator inhibitor 1 (pai-1), their preparation and use
EP1308166A1 (de) * 2001-11-02 2003-05-07 Paion GmbH Desmodus Salivary Plasminogen Activator (DSPA) zur Behandlung von Schlaganfällen

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0352119A2 (en) * 1988-07-20 1990-01-24 Schering Aktiengesellschaft Vampire bat salivary plasminogen activators
WO1991005048A1 (en) * 1989-10-03 1991-04-18 Stichting Centraal Laboratorium Van De Bloedtransfusiedienst Van Het Nederlandse Rode Kruis Mutants of the human plasminogen activator inhibitor 1 (pai-1), their preparation and use
EP1308166A1 (de) * 2001-11-02 2003-05-07 Paion GmbH Desmodus Salivary Plasminogen Activator (DSPA) zur Behandlung von Schlaganfällen
WO2003037363A2 (de) * 2001-11-02 2003-05-08 Paion Gmbh Nicht-neurotoxische plasminogen aktivierende faktoren zur behandlung von schlaganfall

Also Published As

Publication number Publication date
KR101212631B1 (ko) 2012-12-14
EP1622639B1 (de) 2013-01-16
NO20055692D0 (no) 2005-12-01
EP1622639A2 (de) 2006-02-08
BRPI0409865A (pt) 2006-05-16
PL1622639T3 (pl) 2013-06-28
HRP20050903A2 (en) 2006-08-31
WO2004096268A2 (de) 2004-11-11
KR20060020616A (ko) 2006-03-06
CA2524573A1 (en) 2004-11-11
NZ543367A (en) 2010-06-25
WO2004096268A3 (de) 2005-04-21
NO337485B1 (no) 2016-04-25
NO20055692L (no) 2006-01-30
JP2006525270A (ja) 2006-11-09

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
PPPP Transfer of rights

Owner name: H. LUNDBECK A/S, DK

B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20170306

Year of fee payment: 14

PBON Lapse due to non-payment of renewal fee

Effective date: 20180430