DE60323628D1 - Intrakraniale behandlung neuropsychiatrischer krankheiten mit clostridium neurotoxinen wie botulinus toxin - Google Patents
Intrakraniale behandlung neuropsychiatrischer krankheiten mit clostridium neurotoxinen wie botulinus toxinInfo
- Publication number
- DE60323628D1 DE60323628D1 DE60323628T DE60323628T DE60323628D1 DE 60323628 D1 DE60323628 D1 DE 60323628D1 DE 60323628 T DE60323628 T DE 60323628T DE 60323628 T DE60323628 T DE 60323628T DE 60323628 D1 DE60323628 D1 DE 60323628D1
- Authority
- DE
- Germany
- Prior art keywords
- neurotoxines
- intrakranial
- clostridium
- treatment
- neuropsychiatric diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/143,078 US6921538B2 (en) | 2002-05-10 | 2002-05-10 | Therapeutic treatments for neuropsychiatric disorders |
PCT/US2003/011416 WO2003094955A1 (en) | 2002-05-10 | 2003-04-11 | Intracranial treatment of neuropsychiatric disorders by clostridial neurotoxins such as botulinum toxin |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60323628D1 true DE60323628D1 (de) | 2008-10-30 |
Family
ID=29400026
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60323628T Expired - Lifetime DE60323628D1 (de) | 2002-05-10 | 2003-04-11 | Intrakraniale behandlung neuropsychiatrischer krankheiten mit clostridium neurotoxinen wie botulinus toxin |
Country Status (10)
Country | Link |
---|---|
US (3) | US6921538B2 (de) |
EP (1) | EP1503790B1 (de) |
JP (1) | JP4624777B2 (de) |
AT (1) | ATE408416T1 (de) |
AU (1) | AU2003221922B8 (de) |
BR (1) | BR0309888A (de) |
CA (1) | CA2484774C (de) |
DE (1) | DE60323628D1 (de) |
ES (1) | ES2314193T3 (de) |
WO (1) | WO2003094955A1 (de) |
Families Citing this family (84)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8762065B2 (en) | 1998-08-05 | 2014-06-24 | Cyberonics, Inc. | Closed-loop feedback-driven neuromodulation |
US9375573B2 (en) | 1998-08-05 | 2016-06-28 | Cyberonics, Inc. | Systems and methods for monitoring a patient's neurological disease state |
US7209787B2 (en) | 1998-08-05 | 2007-04-24 | Bioneuronics Corporation | Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease |
US7747325B2 (en) | 1998-08-05 | 2010-06-29 | Neurovista Corporation | Systems and methods for monitoring a patient's neurological disease state |
US9042988B2 (en) | 1998-08-05 | 2015-05-26 | Cyberonics, Inc. | Closed-loop vagus nerve stimulation |
US9415222B2 (en) | 1998-08-05 | 2016-08-16 | Cyberonics, Inc. | Monitoring an epilepsy disease state with a supervisory module |
US9320900B2 (en) | 1998-08-05 | 2016-04-26 | Cyberonics, Inc. | Methods and systems for determining subject-specific parameters for a neuromodulation therapy |
WO2001039664A1 (en) * | 1999-12-02 | 2001-06-07 | The General Hospital Corporation | Method and apparatus for measuring indices of brain activity |
US6306403B1 (en) * | 2000-06-14 | 2001-10-23 | Allergan Sales, Inc. | Method for treating parkinson's disease with a botulinum toxin |
US6921538B2 (en) * | 2002-05-10 | 2005-07-26 | Allergan, Inc. | Therapeutic treatments for neuropsychiatric disorders |
US7393537B2 (en) * | 2003-04-25 | 2008-07-01 | Allergan, Inc. | Botulinum toxin for treatment of obsessive compulsive finger biting disorder |
US20040226556A1 (en) | 2003-05-13 | 2004-11-18 | Deem Mark E. | Apparatus for treating asthma using neurotoxin |
US8609112B2 (en) | 2003-10-29 | 2013-12-17 | Allergan, Inc. | Botulinum toxin treatments of depression |
US8617572B2 (en) | 2003-10-29 | 2013-12-31 | Allergan, Inc. | Botulinum toxin treatments of depression |
US8734810B2 (en) * | 2003-10-29 | 2014-05-27 | Allergan, Inc. | Botulinum toxin treatments of neurological and neuropsychiatric disorders |
US8609113B2 (en) | 2003-10-29 | 2013-12-17 | Allergan, Inc. | Botulinum toxin treatments of depression |
US20050129677A1 (en) * | 2003-12-10 | 2005-06-16 | Shengwen Li | Lipid rafts and clostridial toxins |
US20100266638A1 (en) | 2004-02-26 | 2010-10-21 | Allergan, Inc. | Headache treatment method |
US7514088B2 (en) * | 2005-03-15 | 2009-04-07 | Allergan, Inc. | Multivalent Clostridial toxin derivatives and methods of their use |
US7811584B2 (en) * | 2004-06-30 | 2010-10-12 | Allergan, Inc. | Multivalent clostridial toxins |
AU2005279741B2 (en) | 2004-09-01 | 2011-10-06 | Allergan, Inc. | Degradable clostridial toxins |
US20060073208A1 (en) * | 2004-10-01 | 2006-04-06 | Allergan, Inc. | Cosmetic neurotoxin compositions and methods |
AU2006227816B2 (en) | 2005-03-15 | 2012-04-05 | Allergan, Inc. | Modified clostridial toxins with enhanced targeting capabilities for endogenous clostridial toxin receptor systems |
AU2006340711C1 (en) | 2005-04-05 | 2013-02-07 | Allergan, Inc. | Clostridial toxin activity assays |
US8926991B2 (en) * | 2005-06-14 | 2015-01-06 | Botulinum Toxin Research Associates, Inc. | Botulinum toxin and the treatment of primary disorders of mood and affect |
US20150258183A1 (en) | 2006-06-07 | 2015-09-17 | Botulinum Toxin Research Associates, Inc. | Botulinum Toxin and the Treatment of Primary Disorders of Mood and Affect |
CA2948238A1 (en) * | 2005-06-14 | 2006-12-28 | Revance Therapeutics, Inc. | Botulinum toxin and the treatment of primary disorders of mood and affect |
US7655243B2 (en) | 2005-07-22 | 2010-02-02 | The Foundry, Llc | Methods and systems for toxin delivery to the nasal cavity |
US10052465B2 (en) | 2005-07-22 | 2018-08-21 | The Foundry, Llc | Methods and systems for toxin delivery to the nasal cavity |
EP1906923B1 (de) | 2005-07-22 | 2018-01-24 | The Foundry, LLC | Systeme und verfahren zur freisetzung eines therapeutischen wirkstoffes |
US8868172B2 (en) | 2005-12-28 | 2014-10-21 | Cyberonics, Inc. | Methods and systems for recommending an appropriate action to a patient for managing epilepsy and other neurological disorders |
US8725243B2 (en) | 2005-12-28 | 2014-05-13 | Cyberonics, Inc. | Methods and systems for recommending an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders |
TWI417301B (zh) * | 2006-02-21 | 2013-12-01 | Wyeth Corp | 對抗人類介白素-22(il-22)之抗體及其用途 |
US20080027347A1 (en) | 2006-06-23 | 2008-01-31 | Neuro Vista Corporation, A Delaware Corporation | Minimally Invasive Monitoring Methods |
US8295934B2 (en) | 2006-11-14 | 2012-10-23 | Neurovista Corporation | Systems and methods of reducing artifact in neurological stimulation systems |
US7983740B2 (en) * | 2006-12-22 | 2011-07-19 | Washington University | High performance imaging system for diffuse optical tomography and associated method of use |
US9898656B2 (en) | 2007-01-25 | 2018-02-20 | Cyberonics, Inc. | Systems and methods for identifying a contra-ictal condition in a subject |
US20080183097A1 (en) | 2007-01-25 | 2008-07-31 | Leyde Kent W | Methods and Systems for Measuring a Subject's Susceptibility to a Seizure |
US8036736B2 (en) | 2007-03-21 | 2011-10-11 | Neuro Vista Corporation | Implantable systems and methods for identifying a contra-ictal condition in a subject |
US9788744B2 (en) | 2007-07-27 | 2017-10-17 | Cyberonics, Inc. | Systems for monitoring brain activity and patient advisory device |
US9259591B2 (en) | 2007-12-28 | 2016-02-16 | Cyberonics, Inc. | Housing for an implantable medical device |
US20090171168A1 (en) | 2007-12-28 | 2009-07-02 | Leyde Kent W | Systems and Method for Recording Clinical Manifestations of a Seizure |
US8483831B1 (en) | 2008-02-15 | 2013-07-09 | Holaira, Inc. | System and method for bronchial dilation |
US9480425B2 (en) * | 2008-04-17 | 2016-11-01 | Washington University | Task-less optical mapping of dynamic brain function using resting state functional connectivity |
CA2723806C (en) | 2008-05-09 | 2022-05-31 | Innovative Pulmonary Solutions, Inc. | Systems, assemblies, and methods for treating a bronchial tree |
WO2010013495A1 (ja) * | 2008-07-31 | 2010-02-04 | 財団法人化学及血清療法研究所 | 高度精製ボツリヌス毒素治療剤を有効成分として含有する薬学的組成物およびその利用 |
US8849390B2 (en) | 2008-12-29 | 2014-09-30 | Cyberonics, Inc. | Processing for multi-channel signals |
US8588933B2 (en) | 2009-01-09 | 2013-11-19 | Cyberonics, Inc. | Medical lead termination sleeve for implantable medical devices |
US8786624B2 (en) | 2009-06-02 | 2014-07-22 | Cyberonics, Inc. | Processing for multi-channel signals |
WO2011041483A2 (en) | 2009-09-30 | 2011-04-07 | Toxcure, Inc. | Use of botulinum neurotoxin to treat substance addictions |
EP4193948A1 (de) | 2009-10-27 | 2023-06-14 | Nuvaira, Inc. | Freisetzungsvorrichtungen mit kühlbaren energieemissionsanordnungen |
EP4111995A1 (de) | 2009-11-11 | 2023-01-04 | Nuvaira, Inc. | Vorrichtung zur gewebebehandlung und stenosekontrolleti |
US8911439B2 (en) | 2009-11-11 | 2014-12-16 | Holaira, Inc. | Non-invasive and minimally invasive denervation methods and systems for performing the same |
JP2011157331A (ja) * | 2010-02-03 | 2011-08-18 | Chemo-Sero-Therapeutic Research Inst | 高用量投与が可能なボツリヌス毒素製剤 |
US9643019B2 (en) | 2010-02-12 | 2017-05-09 | Cyberonics, Inc. | Neurological monitoring and alerts |
US8940308B2 (en) | 2010-03-30 | 2015-01-27 | Allergan, Inc. | Methods for treating depression |
WO2012174123A1 (en) | 2011-06-13 | 2012-12-20 | Allergan, Inc. | Treatment of psychological trauma |
EP2836193B1 (de) | 2012-04-13 | 2018-01-31 | Lubrizol Advanced Materials, Inc. | Verbindungen zur hemmung neuronaler exozytose (ii) |
EP2649984A1 (de) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Verbindungen zur Hemmung neuronaler Exozytose |
EP2649983A1 (de) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Verbindungen zur Hemmung neuronaler Exozytose (II) |
EP2649985A1 (de) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Verbindungen zur Hemmung neuronaler Exozytose (III) |
US9005628B2 (en) | 2012-10-04 | 2015-04-14 | Dublin City University | Biotherapy for pain |
EP2919807B1 (de) * | 2012-11-16 | 2018-07-11 | Finzi, Eric | Behandlung von posttraumatischen stresszuständen mit botulinumtoxin a |
US9398933B2 (en) | 2012-12-27 | 2016-07-26 | Holaira, Inc. | Methods for improving drug efficacy including a combination of drug administration and nerve modulation |
GB201312317D0 (en) | 2013-07-09 | 2013-08-21 | Syntaxin Ltd | Cationic neurotoxins |
GB201313356D0 (en) * | 2013-07-26 | 2013-09-11 | Ucl Business Plc | Therapeutic Intervention |
US9216210B2 (en) | 2013-12-23 | 2015-12-22 | Dublin City University | Multiprotease therapeutics for chronic pain |
US9950194B2 (en) | 2014-09-09 | 2018-04-24 | Mevion Medical Systems, Inc. | Patient positioning system |
US10647750B2 (en) | 2015-01-09 | 2020-05-12 | Ipsen Bioinnovation Limited | Cationic neurotoxins |
WO2016149092A1 (en) | 2015-03-13 | 2016-09-22 | Allergan, Inc. | Improved injection paradigm for administration of botulinum toxins |
GB201517450D0 (en) | 2015-10-02 | 2015-11-18 | Ipsen Biopharm Ltd | Method |
GB201607901D0 (en) | 2016-05-05 | 2016-06-22 | Ipsen Biopharm Ltd | Chimeric neurotoxins |
EP3263710A1 (de) | 2016-07-01 | 2018-01-03 | Ipsen Biopharm Limited | Herstellung von aktivierten clostridien-neurotoxinen |
US20210277071A1 (en) | 2016-09-29 | 2021-09-09 | Ipsen Biopharm Limited | Hybrid neurotoxins |
US10786010B2 (en) | 2017-12-15 | 2020-09-29 | Rai Strategic Holdings, Inc. | Aerosol delivery device with multiple aerosol delivery pathways |
JP7186228B2 (ja) | 2018-02-26 | 2022-12-08 | イプセン バイオファーム リミテッド | 非細胞毒性プロテアーゼの注入を案内するための超音波の使用 |
WO2020055240A1 (en) | 2018-09-10 | 2020-03-19 | ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) | Musk inhibition |
AU2020365148B2 (en) | 2019-10-18 | 2022-10-27 | Penland Foundation | Botulinum toxin for use in treatment |
GB201917265D0 (en) | 2019-11-27 | 2020-01-08 | Univ Sheffield | Bonded neurotoxins |
TW202136518A (zh) | 2019-12-20 | 2021-10-01 | 瑞士商葛德瑪控股公司 | 生產肉毒桿菌毒素的方法 |
BR112022021065A2 (pt) | 2020-04-17 | 2023-02-23 | Univ New York | Anticorpos terapêuticos de musk |
CN113832069B (zh) * | 2020-11-30 | 2024-01-30 | 河南农业大学 | 丁酸梭菌及其应用 |
GB202103372D0 (en) | 2021-03-11 | 2021-04-28 | Ipsen Biopharm Ltd | Modified clostridial neurotoxins |
WO2024069191A1 (en) | 2022-09-30 | 2024-04-04 | Ipsen Biopharm Limited | Clostridial neurotoxin for use in a treatment of bladder pain syndrome |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4741902A (en) * | 1986-07-14 | 1988-05-03 | Haast William E | Compositions for treatment of neurological and related disorders |
US5352447A (en) * | 1987-10-05 | 1994-10-04 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Immunotoxins for treatment of intracranial lesions and as adjunct to chemotherapy |
DE4004573A1 (de) * | 1989-02-17 | 1990-08-23 | Tanabe Seiyaku Co | Neues versuchstier und seine herstellung |
US5549884A (en) * | 1992-10-28 | 1996-08-27 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Rat or mouse exhibiting behaviors associated with human schizophrenia |
US5562907A (en) * | 1993-05-14 | 1996-10-08 | Arnon; Stephen S. | Method to prevent side-effects and insensitivity to the therapeutic uses of toxins |
US5545617A (en) * | 1993-11-12 | 1996-08-13 | The Schepens Eye Research Institute, Inc. | Therapeutic regulation of abnormal conjunctival goblet cell mucous secretion |
EP0737074B1 (de) * | 1993-12-28 | 2001-08-01 | Allergan Sales, Inc. | Botulinumtoxine zur behandlung von hyperhydrosis |
US6974578B1 (en) * | 1993-12-28 | 2005-12-13 | Allergan, Inc. | Method for treating secretions and glands using botulinum toxin |
US5766605A (en) * | 1994-04-15 | 1998-06-16 | Mount Sinai School Of Medicine Of The City University Of New York | Treatment of autonomic nerve dysfunction with botulinum toxin |
DK0758900T3 (da) * | 1994-05-09 | 2002-07-29 | William J Binder | Botulinumtoksin til reduktion af migræne-hovedpinesmerter |
US6203794B1 (en) * | 1994-05-31 | 2001-03-20 | Allergan Sales, Inc. | Modification of clostridial toxins for use as transport proteins |
SE9401965D0 (sv) * | 1994-06-07 | 1994-06-07 | Astra Ab | New compounds |
GB9508204D0 (en) * | 1995-04-21 | 1995-06-07 | Speywood Lab Ltd | A novel agent able to modify peripheral afferent function |
US6071493A (en) * | 1996-09-20 | 2000-06-06 | Baylor College Of Medicine | Method of screening for an agent that inhibits mononuclear phagocyte-plaque component complex formation |
US6272370B1 (en) * | 1998-08-07 | 2001-08-07 | The Regents Of University Of Minnesota | MR-visible medical device for neurological interventions using nonlinear magnetic stereotaxis and a method imaging |
EP1073455B1 (de) * | 1998-04-29 | 2003-10-08 | Allergan, Inc. | Zusammensetzungen und methode zum verlängung der wirkung des clostridiumsneurotoxins |
IL141588A0 (en) * | 1998-09-15 | 2002-03-10 | M & E Biotech As | Method for down-regulating osteoprotegerin ligand activity |
AU1706400A (en) * | 1998-10-27 | 2000-05-15 | Mayo Foundation For Medical Education And Research | Methods for enhancing wound healing |
US6545126B1 (en) * | 1999-03-18 | 2003-04-08 | Wisconsin Alumni Research Foundation | Chimeric toxins |
US6113915A (en) * | 1999-10-12 | 2000-09-05 | Allergan Sales, Inc. | Methods for treating pain |
US6429189B1 (en) * | 1999-12-10 | 2002-08-06 | Botulinum Toxin Research Associates, Inc. | Cytotoxin (non-neurotoxin) for the treatment of human headache disorders and inflammatory diseases |
US6524580B1 (en) * | 2000-02-15 | 2003-02-25 | Allergan Sales, Inc. | Method for treating thyroid disorders |
US20010036943A1 (en) * | 2000-04-07 | 2001-11-01 | Coe Jotham W. | Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines |
US6464986B1 (en) * | 2000-04-14 | 2002-10-15 | Allegan Sales, Inc. | Method for treating pain by peripheral administration of a neurotoxin |
US6306423B1 (en) * | 2000-06-02 | 2001-10-23 | Allergan Sales, Inc. | Neurotoxin implant |
US6306403B1 (en) * | 2000-06-14 | 2001-10-23 | Allergan Sales, Inc. | Method for treating parkinson's disease with a botulinum toxin |
US6827931B1 (en) * | 2000-10-20 | 2004-12-07 | Allergan, Inc. | Method for treating endocrine disorders |
US6787517B1 (en) * | 2000-12-29 | 2004-09-07 | Allergan, Inc. | Agent and methods for treating pain |
US20020192239A1 (en) * | 2001-01-09 | 2002-12-19 | Borodic Gary E. | Use of botulinum toxin for the treatment of chronic facial pain |
US7063860B2 (en) * | 2001-08-13 | 2006-06-20 | University Of Pittsburgh | Application of lipid vehicles and use for drug delivery |
US6623742B2 (en) * | 2001-09-17 | 2003-09-23 | Allergan, Inc. | Methods for treating fibromyalgia |
US7255866B2 (en) * | 2001-09-17 | 2007-08-14 | Allergan, Inc. | Botulinum toxin therapy for fibromyalgia |
DE10150415A1 (de) | 2001-10-11 | 2003-05-15 | Andres O Ceballos-Baumann | Arzneimittel zur Prophylaxe und Therapie von Depressionen |
US6921538B2 (en) * | 2002-05-10 | 2005-07-26 | Allergan, Inc. | Therapeutic treatments for neuropsychiatric disorders |
US7390496B2 (en) * | 2003-04-25 | 2008-06-24 | Allergan, Inc. | Therapeutic treatments for repetitive hand washing |
US8734810B2 (en) * | 2003-10-29 | 2014-05-27 | Allergan, Inc. | Botulinum toxin treatments of neurological and neuropsychiatric disorders |
US7270287B2 (en) * | 2004-01-06 | 2007-09-18 | Allergan, Inc. | Botulinum toxin treatment for kinesia |
US7897147B2 (en) * | 2004-10-20 | 2011-03-01 | Allergan, Inc. | Treatment of premenstrual disorders |
-
2002
- 2002-05-10 US US10/143,078 patent/US6921538B2/en not_active Expired - Lifetime
-
2003
- 2003-04-11 CA CA2484774A patent/CA2484774C/en not_active Expired - Lifetime
- 2003-04-11 DE DE60323628T patent/DE60323628D1/de not_active Expired - Lifetime
- 2003-04-11 ES ES03718383T patent/ES2314193T3/es not_active Expired - Lifetime
- 2003-04-11 EP EP03718383A patent/EP1503790B1/de not_active Expired - Lifetime
- 2003-04-11 WO PCT/US2003/011416 patent/WO2003094955A1/en active IP Right Grant
- 2003-04-11 BR BR0309888-5A patent/BR0309888A/pt not_active Application Discontinuation
- 2003-04-11 AU AU2003221922A patent/AU2003221922B8/en not_active Ceased
- 2003-04-11 AT AT03718383T patent/ATE408416T1/de not_active IP Right Cessation
- 2003-04-11 JP JP2004503038A patent/JP4624777B2/ja not_active Expired - Fee Related
-
2004
- 2004-03-22 US US10/806,972 patent/US7229626B2/en not_active Expired - Lifetime
-
2007
- 2007-05-16 US US11/749,461 patent/US7811587B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2005530770A (ja) | 2005-10-13 |
US20070218085A1 (en) | 2007-09-20 |
WO2003094955A1 (en) | 2003-11-20 |
US7229626B2 (en) | 2007-06-12 |
CA2484774C (en) | 2012-07-10 |
US6921538B2 (en) | 2005-07-26 |
ES2314193T3 (es) | 2009-03-16 |
ATE408416T1 (de) | 2008-10-15 |
EP1503790A1 (de) | 2005-02-09 |
CA2484774A1 (en) | 2003-11-20 |
US7811587B2 (en) | 2010-10-12 |
JP4624777B2 (ja) | 2011-02-02 |
AU2003221922B2 (en) | 2006-09-28 |
EP1503790B1 (de) | 2008-09-17 |
BR0309888A (pt) | 2005-03-22 |
AU2003221922A1 (en) | 2003-11-11 |
US20030211121A1 (en) | 2003-11-13 |
AU2003221922B8 (en) | 2009-06-18 |
US20040180061A1 (en) | 2004-09-16 |
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