BRPI0409865A - injeção intravenosa de ativadores de plasminogênio não neurotóxicos para o tratamento do ataque de apoplexia - Google Patents
injeção intravenosa de ativadores de plasminogênio não neurotóxicos para o tratamento do ataque de apoplexiaInfo
- Publication number
- BRPI0409865A BRPI0409865A BRPI0409865-0A BRPI0409865A BRPI0409865A BR PI0409865 A BRPI0409865 A BR PI0409865A BR PI0409865 A BRPI0409865 A BR PI0409865A BR PI0409865 A BRPI0409865 A BR PI0409865A
- Authority
- BR
- Brazil
- Prior art keywords
- intravenous injection
- plasminogen activators
- neurotoxic plasminogen
- neurotoxic
- stroke attack
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
- A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"INJEçãO INTRAVENOSA DE ATIVADORES DE PLASMINOGêNIO NãO NEUROTóXICOS PARA O TRATAMENTO DO ATAQUE DE APOPLEXIA". A invenção refere-se à aplicação de fatores ativadores de plasminogênio não neurotóxicos, por exemplo, de Desmodus rotundus (DSPA) ou de fatores ativadores de plasminogênio geneticamente modificados, especialmente de origem humana para a preparação de um terápico injetável para o tratamento terapêutico do ataque de apoplexia no homem.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EPPCT/EP03/04608 | 2003-05-02 | ||
PCT/EP2003/004729 WO2004096267A1 (de) | 2003-05-02 | 2003-05-06 | Intravenöse injektion nicht-neurotoxischer plasminogen-aktivatoren zur behandlung von schlaganfall |
PCT/EP2004/004626 WO2004096268A2 (de) | 2003-05-02 | 2004-04-30 | Intravenöse injektion nicht-neurotoxischer plasminogen-aktivatoren zur behandlung von schlaganfall |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0409865A true BRPI0409865A (pt) | 2006-05-16 |
Family
ID=35610451
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0409865-0A BRPI0409865A (pt) | 2003-05-02 | 2004-04-30 | injeção intravenosa de ativadores de plasminogênio não neurotóxicos para o tratamento do ataque de apoplexia |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1622639B1 (pt) |
JP (1) | JP2006525270A (pt) |
KR (1) | KR101212631B1 (pt) |
BR (1) | BRPI0409865A (pt) |
CA (1) | CA2524573A1 (pt) |
HR (1) | HRP20050903B1 (pt) |
NO (1) | NO337485B1 (pt) |
NZ (1) | NZ543367A (pt) |
PL (1) | PL1622639T3 (pt) |
WO (1) | WO2004096268A2 (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10153601A1 (de) | 2001-11-02 | 2003-05-22 | Paion Gmbh | DSPA zur Behandlung von Schlaganfall |
US7759506B2 (en) | 2002-02-25 | 2010-07-20 | Diffusion Pharmaceuticals Llc | Bipolar trans carotenoid salts and their uses |
DE10342518A1 (de) * | 2003-09-12 | 2005-05-12 | Paion Gmbh | Plasminogen-Aktivatoren mit verringerter Lysin-Bindungskapazität |
UA95903C2 (ru) | 2005-02-24 | 2011-09-26 | Дифьюжен Фармасьютикалз Ллк | Транс-каротиноиды, их синтез, лекарственная форма и применение |
WO2008022801A1 (en) * | 2006-08-25 | 2008-02-28 | Paion Deutschland Gmbh | Method for the manufacture of a medicament for treating hemorrhagic stroke |
EP1897554A1 (en) * | 2006-08-25 | 2008-03-12 | PAION Deutschland GmbH | Method for the manufacture of a medicament for treating hemorrhagic stroke |
JP2010524855A (ja) | 2007-04-13 | 2010-07-22 | ディフュージョン・ファーマシューティカルズ・エルエルシー | 末梢血管疾患の前処置としての、及びその処置における双極性トランスカロテノイドの使用 |
ES2847293T3 (es) | 2009-06-10 | 2021-08-02 | Nono Inc | Regímenes de tratamiento para el tratamiento de enfermedades neurológicas |
AU2010263245A1 (en) | 2009-06-22 | 2012-01-19 | Diffusion Pharmaceuticals Llc | Diffusion enhancing compounds and their use alone or with thrombolytics |
US8652476B2 (en) | 2009-07-27 | 2014-02-18 | Niigata University | Pharmaceutical composition for treating ischemic events |
JP5823671B2 (ja) * | 2009-07-27 | 2015-11-25 | 国立大学法人 新潟大学 | 免疫製剤を含む脳梗塞治療用医薬品組成物 |
JP5823672B2 (ja) * | 2009-07-27 | 2015-11-25 | 国立大学法人 新潟大学 | 受容体シグナル伝達阻害剤を含む脳梗塞治療用医薬品組成物 |
AU2011262361A1 (en) | 2010-06-02 | 2013-01-10 | Diffusion Pharmaceuticals Llc | Oral formulations of bipolar trans carotenoids |
DK3427748T3 (da) * | 2011-06-24 | 2022-04-19 | Nono Inc | Kombinationsterapi mod iskæmi |
US9241970B2 (en) | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
KR102489034B1 (ko) | 2016-03-24 | 2023-01-13 | 디퓨젼 파마슈티컬즈 엘엘씨 | 암을 치료하기 위한, 화학 요법 및 방사선 요법과의 양극성 트랜스 카로티노이드의 용도 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE69054B1 (en) * | 1988-07-20 | 1996-08-07 | Schering Ag | Vampire bat salivary plasminogen activators |
NL8902454A (nl) * | 1989-10-03 | 1991-05-01 | Stichting Centraal Lab | Mutanten van de humane plasminogeen activator inhibitor 1 (pai-1), hun bereiding en toepassing, en recombinante polynucleotiden die voor deze mutanten coderende genetische informatie omvatten. |
DE10153601A1 (de) * | 2001-11-02 | 2003-05-22 | Paion Gmbh | DSPA zur Behandlung von Schlaganfall |
-
2004
- 2004-04-30 PL PL04730516T patent/PL1622639T3/pl unknown
- 2004-04-30 EP EP04730516A patent/EP1622639B1/de not_active Expired - Lifetime
- 2004-04-30 JP JP2006505347A patent/JP2006525270A/ja not_active Withdrawn
- 2004-04-30 NZ NZ543367A patent/NZ543367A/en unknown
- 2004-04-30 CA CA002524573A patent/CA2524573A1/en not_active Abandoned
- 2004-04-30 KR KR1020057020820A patent/KR101212631B1/ko not_active IP Right Cessation
- 2004-04-30 BR BRPI0409865-0A patent/BRPI0409865A/pt not_active IP Right Cessation
- 2004-04-30 WO PCT/EP2004/004626 patent/WO2004096268A2/de active Application Filing
-
2005
- 2005-10-17 HR HRP20050903AA patent/HRP20050903B1/hr not_active IP Right Cessation
- 2005-12-01 NO NO20055692A patent/NO337485B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO20055692L (no) | 2006-01-30 |
KR101212631B1 (ko) | 2012-12-14 |
WO2004096268A2 (de) | 2004-11-11 |
KR20060020616A (ko) | 2006-03-06 |
HRP20050903A2 (en) | 2006-08-31 |
WO2004096268A3 (de) | 2005-04-21 |
NO337485B1 (no) | 2016-04-25 |
NZ543367A (en) | 2010-06-25 |
EP1622639B1 (de) | 2013-01-16 |
EP1622639A2 (de) | 2006-02-08 |
PL1622639T3 (pl) | 2013-06-28 |
NO20055692D0 (no) | 2005-12-01 |
CA2524573A1 (en) | 2004-11-11 |
HRP20050903B1 (hr) | 2013-11-22 |
JP2006525270A (ja) | 2006-11-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B25A | Requested transfer of rights approved |
Owner name: H. LUNDBECK A/S. (DK) |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B25E | Requested change of name of applicant rejected |
Owner name: H. LUNDBECK A/S. (DK) |
|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |