HRP20050903A2 - Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke - Google Patents
Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral strokeInfo
- Publication number
- HRP20050903A2 HRP20050903A2 HR20050903A HRP20050903A HRP20050903A2 HR P20050903 A2 HRP20050903 A2 HR P20050903A2 HR 20050903 A HR20050903 A HR 20050903A HR P20050903 A HRP20050903 A HR P20050903A HR P20050903 A2 HRP20050903 A2 HR P20050903A2
- Authority
- HR
- Croatia
- Prior art keywords
- plasminogen
- intravenous injection
- treating cerebral
- cerebral stroke
- neurotoxic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
- A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Abstract
Izum se odnosi na upotrebu ne-neurotoksičnih faktora aktiviranja plazminogena, npr. iz Desmodus rotundus (DSPA) ili genetski modificiranih faktora aktiviranja plazminogena, naročito ljudskog porijekla, za proizvodnju lijeka za injekcije za terapijsko liječenje kapi kod ljudi.The invention relates to the use of non-neurotoxic plasminogen activating factors, e.g. from Desmodus rotundus (DSPA) or genetically modified plasminogen activating factors, in particular of human origin, for the manufacture of a medicament for injection for the therapeutic treatment of drops in humans.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EPPCT/EP03/04608 | 2003-05-02 | ||
PCT/EP2003/004729 WO2004096267A1 (en) | 2003-05-02 | 2003-05-06 | Intravenous injection of non-neurotoxic plasminogen activators for the treatment of stroke |
PCT/EP2004/004626 WO2004096268A2 (en) | 2003-05-02 | 2004-04-30 | Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke |
Publications (2)
Publication Number | Publication Date |
---|---|
HRP20050903A2 true HRP20050903A2 (en) | 2006-08-31 |
HRP20050903B1 HRP20050903B1 (en) | 2013-11-22 |
Family
ID=35610451
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20050903AA HRP20050903B1 (en) | 2003-05-02 | 2005-10-17 | Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1622639B1 (en) |
JP (1) | JP2006525270A (en) |
KR (1) | KR101212631B1 (en) |
BR (1) | BRPI0409865A (en) |
CA (1) | CA2524573A1 (en) |
HR (1) | HRP20050903B1 (en) |
NO (1) | NO337485B1 (en) |
NZ (1) | NZ543367A (en) |
PL (1) | PL1622639T3 (en) |
WO (1) | WO2004096268A2 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10153601A1 (en) | 2001-11-02 | 2003-05-22 | Paion Gmbh | DSPA for the treatment of stroke |
US7759506B2 (en) | 2002-02-25 | 2010-07-20 | Diffusion Pharmaceuticals Llc | Bipolar trans carotenoid salts and their uses |
DE10342518A1 (en) * | 2003-09-12 | 2005-05-12 | Paion Gmbh | Plasminogen activators with reduced lysine binding capacity |
US8030350B2 (en) | 2005-02-24 | 2011-10-04 | Diffusion Pharmaceuticals Llc | Trans carotenoids, their synthesis, formulation and uses |
EP1897554A1 (en) * | 2006-08-25 | 2008-03-12 | PAION Deutschland GmbH | Method for the manufacture of a medicament for treating hemorrhagic stroke |
WO2008022801A1 (en) * | 2006-08-25 | 2008-02-28 | Paion Deutschland Gmbh | Method for the manufacture of a medicament for treating hemorrhagic stroke |
JP2010524855A (en) | 2007-04-13 | 2010-07-22 | ディフュージョン・ファーマシューティカルズ・エルエルシー | Use of bipolar trans carotenoids as and in the pretreatment of peripheral vascular disease |
PL2440230T3 (en) | 2009-06-10 | 2021-06-14 | Nono Inc. | Treatment regimes for treatment of neurological disease |
KR101875843B1 (en) | 2009-06-22 | 2018-07-06 | 디퓨젼 파마슈티컬즈 엘엘씨 | Diffusion enhancing compounds and their use alone or with thrombolytics |
US8652476B2 (en) | 2009-07-27 | 2014-02-18 | Niigata University | Pharmaceutical composition for treating ischemic events |
JP5823671B2 (en) * | 2009-07-27 | 2015-11-25 | 国立大学法人 新潟大学 | Pharmaceutical composition for the treatment of cerebral infarction comprising immunological preparation |
JP5823672B2 (en) * | 2009-07-27 | 2015-11-25 | 国立大学法人 新潟大学 | Pharmaceutical composition for treating cerebral infarction comprising receptor signaling inhibitor |
CN103124498A (en) | 2010-06-02 | 2013-05-29 | 扩散药品有限公司 | Oral formulations of bipolar trans carotenoids |
KR102296106B1 (en) | 2011-06-24 | 2021-08-30 | 노노 인코포레이티드 | Combination therapy with psd-95 inhibitor for ischemia |
US9241970B2 (en) | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
EP3432929A4 (en) | 2016-03-24 | 2019-11-27 | Diffusion Pharmaceuticals LLC | Use of bipolar trans carotenoids with chemotherapy and radiotherapy for treatment of cancer |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK176140B1 (en) * | 1988-07-20 | 2006-09-25 | Schering Ag Patentabteilung | Bat salivary plasminogen activators |
NL8902454A (en) * | 1989-10-03 | 1991-05-01 | Stichting Centraal Lab | MUTANTS OF THE HUMANE PLASMINOGENIC ACTIVATOR INHIBITOR 1 (PAI-1), THEIR PREPARATION AND USE, AND RECOMBINANT POLYNUCLEOTIDES INCLUDING GENETIC INFORMATION CODING FOR THESE MUTANTS. |
DE10153601A1 (en) * | 2001-11-02 | 2003-05-22 | Paion Gmbh | DSPA for the treatment of stroke |
-
2004
- 2004-04-30 KR KR1020057020820A patent/KR101212631B1/en not_active IP Right Cessation
- 2004-04-30 EP EP04730516A patent/EP1622639B1/en not_active Expired - Lifetime
- 2004-04-30 PL PL04730516T patent/PL1622639T3/en unknown
- 2004-04-30 BR BRPI0409865-0A patent/BRPI0409865A/en not_active IP Right Cessation
- 2004-04-30 WO PCT/EP2004/004626 patent/WO2004096268A2/en active Application Filing
- 2004-04-30 NZ NZ543367A patent/NZ543367A/en unknown
- 2004-04-30 JP JP2006505347A patent/JP2006525270A/en not_active Withdrawn
- 2004-04-30 CA CA002524573A patent/CA2524573A1/en not_active Abandoned
-
2005
- 2005-10-17 HR HRP20050903AA patent/HRP20050903B1/en not_active IP Right Cessation
- 2005-12-01 NO NO20055692A patent/NO337485B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR20060020616A (en) | 2006-03-06 |
EP1622639A2 (en) | 2006-02-08 |
WO2004096268A3 (en) | 2005-04-21 |
JP2006525270A (en) | 2006-11-09 |
NO337485B1 (en) | 2016-04-25 |
WO2004096268A2 (en) | 2004-11-11 |
NZ543367A (en) | 2010-06-25 |
NO20055692L (en) | 2006-01-30 |
BRPI0409865A (en) | 2006-05-16 |
CA2524573A1 (en) | 2004-11-11 |
NO20055692D0 (en) | 2005-12-01 |
KR101212631B1 (en) | 2012-12-14 |
PL1622639T3 (en) | 2013-06-28 |
HRP20050903B1 (en) | 2013-11-22 |
EP1622639B1 (en) | 2013-01-16 |
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Legal Events
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A1OB | Publication of a patent application | ||
ARAI | Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application | ||
PPPP | Transfer of rights |
Owner name: H. LUNDBECK A/S, DK |
|
B1PR | Patent granted | ||
ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20170306 Year of fee payment: 14 |
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PBON | Lapse due to non-payment of renewal fee |
Effective date: 20180430 |