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Application filed by Hoffmann La RochefiledCriticalHoffmann La Roche
Publication of ECSP034651ApublicationCriticalpatent/ECSP034651A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Plural Heterocyclic Compounds
(AREA)
Abstract
Activadores de glucocinasa del tipo propionamida sustituida por isoindolin-1-ona para aumentar la secreción de insulina en el tratamiento de la diabetes del tipo II.Glucokinase activators of the propionamide type substituted by isoindolin-1-one to increase insulin secretion in the treatment of type II diabetes.
Compounds derived from substituted pyrazolo-pyrimidines; pharmaceutical composition and combination that comprise them; and its use as inhibitors of pde9 for the treatment, relief and / or prevention of cognitive impairments related to perception, Alzheimer's, sleep disorders, bipolar disorder, diabetes mellitus.
Pyridine derived compounds; preparation procedure; pharmaceutical composition of said compounds; and use in the treatment and / or prophylaxis of type I and / or type II diabetes mellitus.
Tricyclic compounds, with superior affinity for melatonin receptors; pharmaceutical composition; Useful for the prophylaxis or treatment of sleeping sickness and intermediates.