AR046641A1 - USE OF (+) - (2S, 3S) -2- (3-CHLOROPHENYL) -3,5,5-TRIMETHYL-2-MORPHOLINOL - Google Patents

USE OF (+) - (2S, 3S) -2- (3-CHLOROPHENYL) -3,5,5-TRIMETHYL-2-MORPHOLINOL

Info

Publication number
AR046641A1
AR046641A1 ARP040104268A ARP040104268A AR046641A1 AR 046641 A1 AR046641 A1 AR 046641A1 AR P040104268 A ARP040104268 A AR P040104268A AR P040104268 A ARP040104268 A AR P040104268A AR 046641 A1 AR046641 A1 AR 046641A1
Authority
AR
Argentina
Prior art keywords
morpholinol
chlorophenyl
trimethyl
treatment
restless legs
Prior art date
Application number
ARP040104268A
Other languages
Spanish (es)
Inventor
Jean Christophe Barland
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of AR046641A1 publication Critical patent/AR046641A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

El presente se refiere en particular a su uso en el tratamiento del Síndrome de piernas inquietas (SPI), o a su uso en el tratamiento de Trastorno de movimiento periódico de las piernas (TMPP). Reivindicación 1: Uso del (+)-(2S,3S)-2-(3-clorofenil)- 3,5,5-trimetil-2-morfolinol o una de sus sales o solvatos o sus composiciones farmacéuticas en la fabricación de un medicamento para tratar el Síndrome de piernas inquietas.This refers in particular to its use in the treatment of Restless Legs Syndrome (SPI), or its use in the treatment of Periodic Leg Movement Disorder (TMPP). Claim 1: Use of (+) - (2S, 3S) -2- (3-chlorophenyl) - 3,5,5-trimethyl-2-morpholinol or one of its salts or solvates or their pharmaceutical compositions in the manufacture of a medicine to treat restless legs syndrome.

ARP040104268A 2003-11-21 2004-11-19 USE OF (+) - (2S, 3S) -2- (3-CHLOROPHENYL) -3,5,5-TRIMETHYL-2-MORPHOLINOL AR046641A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0327195.4A GB0327195D0 (en) 2003-11-21 2003-11-21 Novel use

Publications (1)

Publication Number Publication Date
AR046641A1 true AR046641A1 (en) 2005-12-14

Family

ID=29764268

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040104268A AR046641A1 (en) 2003-11-21 2004-11-19 USE OF (+) - (2S, 3S) -2- (3-CHLOROPHENYL) -3,5,5-TRIMETHYL-2-MORPHOLINOL

Country Status (7)

Country Link
US (1) US20070142378A1 (en)
EP (1) EP1684765A1 (en)
JP (1) JP2007511577A (en)
AR (1) AR046641A1 (en)
GB (1) GB0327195D0 (en)
TW (1) TW200529858A (en)
WO (1) WO2005053700A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0425445D0 (en) * 2004-11-18 2004-12-22 Smithkline Beecham Corp Novel compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1829544A1 (en) * 1998-01-21 2007-09-05 Glaxo Group Limited Pharmaceutically active morpholinol
US7098206B2 (en) * 1998-01-21 2006-08-29 Smithkline Beecham Corporation Pharmaceutically active morpholinol
US6337328B1 (en) * 1999-03-01 2002-01-08 Sepracor, Inc. Bupropion metabolites and methods of use
US6342496B1 (en) * 1999-03-01 2002-01-29 Sepracor Inc. Bupropion metabolites and methods of use
EP1336406A1 (en) * 2002-02-14 2003-08-20 Solvay Pharmaceuticals B.V. Partial dopamine-D2 receptor agonist plus serotonin and/or noradrenaline inhibitory activity

Also Published As

Publication number Publication date
GB0327195D0 (en) 2003-12-24
US20070142378A1 (en) 2007-06-21
JP2007511577A (en) 2007-05-10
TW200529858A (en) 2005-09-16
WO2005053700A1 (en) 2005-06-16
EP1684765A1 (en) 2006-08-02

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