HRP20050903A2 - Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke - Google Patents
Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral strokeInfo
- Publication number
- HRP20050903A2 HRP20050903A2 HR20050903A HRP20050903A HRP20050903A2 HR P20050903 A2 HRP20050903 A2 HR P20050903A2 HR 20050903 A HR20050903 A HR 20050903A HR P20050903 A HRP20050903 A HR P20050903A HR P20050903 A2 HRP20050903 A2 HR P20050903A2
- Authority
- HR
- Croatia
- Prior art keywords
- plasminogen
- intravenous injection
- treating cerebral
- cerebral stroke
- neurotoxic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
- A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Izum se odnosi na upotrebu ne-neurotoksičnih faktora aktiviranja plazminogena, npr. iz Desmodus rotundus (DSPA) ili genetski modificiranih faktora aktiviranja plazminogena, naročito ljudskog porijekla, za proizvodnju lijeka za injekcije za terapijsko liječenje kapi kod ljudi.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EPPCT/EP2003/004608 | 2003-05-02 | ||
PCT/EP2003/004729 WO2004096267A1 (de) | 2003-05-02 | 2003-05-06 | Intravenöse injektion nicht-neurotoxischer plasminogen-aktivatoren zur behandlung von schlaganfall |
PCT/EP2004/004626 WO2004096268A2 (de) | 2003-05-02 | 2004-04-30 | Intravenöse injektion nicht-neurotoxischer plasminogen-aktivatoren zur behandlung von schlaganfall |
Publications (2)
Publication Number | Publication Date |
---|---|
HRP20050903A2 true HRP20050903A2 (en) | 2006-08-31 |
HRP20050903B1 HRP20050903B1 (hr) | 2013-11-22 |
Family
ID=35610451
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20050903AA HRP20050903B1 (hr) | 2003-05-02 | 2005-10-17 | Intravenska injekcija ne-neurotoksiäśnih aktivatora plazminogena za tretman kapi |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1622639B1 (hr) |
JP (1) | JP2006525270A (hr) |
KR (1) | KR101212631B1 (hr) |
BR (1) | BRPI0409865A (hr) |
CA (1) | CA2524573A1 (hr) |
HR (1) | HRP20050903B1 (hr) |
NO (1) | NO337485B1 (hr) |
NZ (1) | NZ543367A (hr) |
PL (1) | PL1622639T3 (hr) |
WO (1) | WO2004096268A2 (hr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10153601A1 (de) | 2001-11-02 | 2003-05-22 | Paion Gmbh | DSPA zur Behandlung von Schlaganfall |
US7759506B2 (en) | 2002-02-25 | 2010-07-20 | Diffusion Pharmaceuticals Llc | Bipolar trans carotenoid salts and their uses |
DE10342518A1 (de) * | 2003-09-12 | 2005-05-12 | Paion Gmbh | Plasminogen-Aktivatoren mit verringerter Lysin-Bindungskapazität |
NZ561664A (en) | 2005-02-24 | 2011-02-25 | Diffusion Pharmaceuticals Llc | Trans carotenoids, their synthesis, formulation and uses |
WO2008022801A1 (en) * | 2006-08-25 | 2008-02-28 | Paion Deutschland Gmbh | Method for the manufacture of a medicament for treating hemorrhagic stroke |
EP1897554A1 (en) * | 2006-08-25 | 2008-03-12 | PAION Deutschland GmbH | Method for the manufacture of a medicament for treating hemorrhagic stroke |
CN101687757A (zh) | 2007-04-13 | 2010-03-31 | 扩散药品有限公司 | 双极性反式类胡萝卜素作为预治疗及其在周围血管疾病的治疗中的应用 |
AU2010258664B2 (en) | 2009-06-10 | 2015-05-28 | Nono Inc. | Model systems and treatment regimes for treatment of neurological disease |
EP3539542B1 (en) | 2009-06-22 | 2023-04-19 | Diffusion Pharmaceuticals LLC | Diffusion enhancing compounds and their use with a thrombolytic |
US8652476B2 (en) | 2009-07-27 | 2014-02-18 | Niigata University | Pharmaceutical composition for treating ischemic events |
JP5823672B2 (ja) * | 2009-07-27 | 2015-11-25 | 国立大学法人 新潟大学 | 受容体シグナル伝達阻害剤を含む脳梗塞治療用医薬品組成物 |
JP5823671B2 (ja) * | 2009-07-27 | 2015-11-25 | 国立大学法人 新潟大学 | 免疫製剤を含む脳梗塞治療用医薬品組成物 |
AU2011262361A1 (en) | 2010-06-02 | 2013-01-10 | Diffusion Pharmaceuticals Llc | Oral formulations of bipolar trans carotenoids |
KR20220106862A (ko) | 2011-06-24 | 2022-07-29 | 노노 인코포레이티드 | 허혈에 대한 psd-95 억제제와의 조합 요법 |
US9241970B2 (en) | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
JP7032320B2 (ja) | 2016-03-24 | 2022-03-08 | ディフュージョン・ファーマシューティカルズ・エルエルシー | 癌を処置するための、化学療法及び放射線療法を伴う二極性トランスカロテノイドの使用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE69054B1 (en) * | 1988-07-20 | 1996-08-07 | Schering Ag | Vampire bat salivary plasminogen activators |
NL8902454A (nl) * | 1989-10-03 | 1991-05-01 | Stichting Centraal Lab | Mutanten van de humane plasminogeen activator inhibitor 1 (pai-1), hun bereiding en toepassing, en recombinante polynucleotiden die voor deze mutanten coderende genetische informatie omvatten. |
DE10153601A1 (de) * | 2001-11-02 | 2003-05-22 | Paion Gmbh | DSPA zur Behandlung von Schlaganfall |
-
2004
- 2004-04-30 PL PL04730516T patent/PL1622639T3/pl unknown
- 2004-04-30 CA CA002524573A patent/CA2524573A1/en not_active Abandoned
- 2004-04-30 JP JP2006505347A patent/JP2006525270A/ja not_active Withdrawn
- 2004-04-30 NZ NZ543367A patent/NZ543367A/en unknown
- 2004-04-30 BR BRPI0409865-0A patent/BRPI0409865A/pt not_active IP Right Cessation
- 2004-04-30 WO PCT/EP2004/004626 patent/WO2004096268A2/de active Application Filing
- 2004-04-30 EP EP04730516A patent/EP1622639B1/de not_active Expired - Lifetime
- 2004-04-30 KR KR1020057020820A patent/KR101212631B1/ko not_active IP Right Cessation
-
2005
- 2005-10-17 HR HRP20050903AA patent/HRP20050903B1/hr not_active IP Right Cessation
- 2005-12-01 NO NO20055692A patent/NO337485B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NO20055692D0 (no) | 2005-12-01 |
NZ543367A (en) | 2010-06-25 |
PL1622639T3 (pl) | 2013-06-28 |
KR20060020616A (ko) | 2006-03-06 |
KR101212631B1 (ko) | 2012-12-14 |
EP1622639A2 (de) | 2006-02-08 |
BRPI0409865A (pt) | 2006-05-16 |
WO2004096268A3 (de) | 2005-04-21 |
WO2004096268A2 (de) | 2004-11-11 |
NO20055692L (no) | 2006-01-30 |
HRP20050903B1 (hr) | 2013-11-22 |
EP1622639B1 (de) | 2013-01-16 |
CA2524573A1 (en) | 2004-11-11 |
NO337485B1 (no) | 2016-04-25 |
JP2006525270A (ja) | 2006-11-09 |
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Legal Events
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A1OB | Publication of a patent application | ||
ARAI | Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application | ||
PPPP | Transfer of rights |
Owner name: H. LUNDBECK A/S, DK |
|
B1PR | Patent granted | ||
ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20170306 Year of fee payment: 14 |
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PBON | Lapse due to non-payment of renewal fee |
Effective date: 20180430 |