BRPI0409865A - injeção intravenosa de ativadores de plasminogênio não neurotóxicos para o tratamento do ataque de apoplexia - Google Patents
injeção intravenosa de ativadores de plasminogênio não neurotóxicos para o tratamento do ataque de apoplexiaInfo
- Publication number
- BRPI0409865A BRPI0409865A BRPI0409865-0A BRPI0409865A BRPI0409865A BR PI0409865 A BRPI0409865 A BR PI0409865A BR PI0409865 A BRPI0409865 A BR PI0409865A BR PI0409865 A BRPI0409865 A BR PI0409865A
- Authority
- BR
- Brazil
- Prior art keywords
- intravenous injection
- plasminogen activators
- neurotoxic plasminogen
- neurotoxic
- stroke attack
- Prior art date
Links
- 231100000501 nonneurotoxic Toxicity 0.000 title abstract 3
- 102000001938 Plasminogen Activators Human genes 0.000 title abstract 2
- 108010001014 Plasminogen Activators Proteins 0.000 title abstract 2
- 238000010253 intravenous injection Methods 0.000 title abstract 2
- 229940127126 plasminogen activator Drugs 0.000 title abstract 2
- 102000013566 Plasminogen Human genes 0.000 abstract 2
- 108010051456 Plasminogen Proteins 0.000 abstract 2
- 230000003213 activating effect Effects 0.000 abstract 2
- 206010010904 Convulsion Diseases 0.000 abstract 1
- 241000288900 Desmodus rotundus Species 0.000 abstract 1
- ALPWRKFXEOAUDR-GKEJWYBXSA-M sodium;[(2r)-2,3-di(octadecanoyloxy)propyl] hydrogen phosphate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)([O-])=O)OC(=O)CCCCCCCCCCCCCCCCC ALPWRKFXEOAUDR-GKEJWYBXSA-M 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
- A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP03/04608 | 2003-05-02 | ||
| PCT/EP2003/004729 WO2004096267A1 (de) | 2003-05-02 | 2003-05-06 | Intravenöse injektion nicht-neurotoxischer plasminogen-aktivatoren zur behandlung von schlaganfall |
| PCT/EP2004/004626 WO2004096268A2 (de) | 2003-05-02 | 2004-04-30 | Intravenöse injektion nicht-neurotoxischer plasminogen-aktivatoren zur behandlung von schlaganfall |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0409865A true BRPI0409865A (pt) | 2006-05-16 |
Family
ID=35610451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0409865-0A BRPI0409865A (pt) | 2003-05-02 | 2004-04-30 | injeção intravenosa de ativadores de plasminogênio não neurotóxicos para o tratamento do ataque de apoplexia |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1622639B1 (enExample) |
| JP (1) | JP2006525270A (enExample) |
| KR (1) | KR101212631B1 (enExample) |
| BR (1) | BRPI0409865A (enExample) |
| CA (1) | CA2524573A1 (enExample) |
| HR (1) | HRP20050903B1 (enExample) |
| NO (1) | NO337485B1 (enExample) |
| NZ (1) | NZ543367A (enExample) |
| PL (1) | PL1622639T3 (enExample) |
| WO (1) | WO2004096268A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10153601A1 (de) | 2001-11-02 | 2003-05-22 | Paion Gmbh | DSPA zur Behandlung von Schlaganfall |
| US7759506B2 (en) | 2002-02-25 | 2010-07-20 | Diffusion Pharmaceuticals Llc | Bipolar trans carotenoid salts and their uses |
| DE10342518A1 (de) * | 2003-09-12 | 2005-05-12 | Paion Gmbh | Plasminogen-Aktivatoren mit verringerter Lysin-Bindungskapazität |
| EA017982B1 (ru) | 2005-02-24 | 2013-04-30 | ДИФФЬЮЖН ФАРМАСЬЮТИКАЛЗ ЭлЭлСи | Фармацевтическая композиция на основе транскаротиноидов и способы лечения опухоли |
| EP1897554A1 (en) * | 2006-08-25 | 2008-03-12 | PAION Deutschland GmbH | Method for the manufacture of a medicament for treating hemorrhagic stroke |
| WO2008022801A1 (en) * | 2006-08-25 | 2008-02-28 | Paion Deutschland Gmbh | Method for the manufacture of a medicament for treating hemorrhagic stroke |
| BRPI0810647A2 (pt) | 2007-04-13 | 2014-11-04 | Diffusion Pharmaceuticals Llc | " uso de trans carotenóides bipolares como um pré-tratamento e no tratamento de doença vascular periférica ". |
| DK2440230T3 (da) | 2009-06-10 | 2021-01-18 | Nono Inc | Behandlingsregimener til behandling af neurologisk sygdom |
| EP3539542B1 (en) | 2009-06-22 | 2023-04-19 | Diffusion Pharmaceuticals LLC | Diffusion enhancing compounds and their use with a thrombolytic |
| US8652476B2 (en) | 2009-07-27 | 2014-02-18 | Niigata University | Pharmaceutical composition for treating ischemic events |
| JP5823671B2 (ja) * | 2009-07-27 | 2015-11-25 | 国立大学法人 新潟大学 | 免疫製剤を含む脳梗塞治療用医薬品組成物 |
| JP5823672B2 (ja) * | 2009-07-27 | 2015-11-25 | 国立大学法人 新潟大学 | 受容体シグナル伝達阻害剤を含む脳梗塞治療用医薬品組成物 |
| ES2654945T3 (es) | 2010-06-02 | 2018-02-15 | Diffusion Pharmaceuticals Llc | Formulaciones orales de carotenoides trans bipolares |
| AU2012274910B2 (en) | 2011-06-24 | 2017-05-11 | Nono, Inc. | Combination therapy with PSD-95 inhibitor for ischemia |
| US9241970B2 (en) | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
| EP3432929A4 (en) | 2016-03-24 | 2019-11-27 | Diffusion Pharmaceuticals LLC | USE OF BIPOLAR TRANSCAROTINOIDS WITH CHEMOTHERAPY AND RADIOTHERAPY FOR THE TREATMENT OF CANCER |
| US10617756B2 (en) | 2017-01-05 | 2020-04-14 | Shimojani, LLC | Drug regimen for treatment of cerebral ischemia |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK176140B1 (da) * | 1988-07-20 | 2006-09-25 | Schering Ag Patentabteilung | Flagermusspyt-plasminogenaktivatorer |
| NL8902454A (nl) * | 1989-10-03 | 1991-05-01 | Stichting Centraal Lab | Mutanten van de humane plasminogeen activator inhibitor 1 (pai-1), hun bereiding en toepassing, en recombinante polynucleotiden die voor deze mutanten coderende genetische informatie omvatten. |
| DE10153601A1 (de) * | 2001-11-02 | 2003-05-22 | Paion Gmbh | DSPA zur Behandlung von Schlaganfall |
-
2004
- 2004-04-30 KR KR1020057020820A patent/KR101212631B1/ko not_active Expired - Fee Related
- 2004-04-30 CA CA002524573A patent/CA2524573A1/en not_active Abandoned
- 2004-04-30 JP JP2006505347A patent/JP2006525270A/ja not_active Withdrawn
- 2004-04-30 BR BRPI0409865-0A patent/BRPI0409865A/pt not_active IP Right Cessation
- 2004-04-30 HR HRP20050903AA patent/HRP20050903B1/hr not_active IP Right Cessation
- 2004-04-30 EP EP04730516A patent/EP1622639B1/de not_active Expired - Lifetime
- 2004-04-30 PL PL04730516T patent/PL1622639T3/pl unknown
- 2004-04-30 NZ NZ543367A patent/NZ543367A/en not_active IP Right Cessation
- 2004-04-30 WO PCT/EP2004/004626 patent/WO2004096268A2/de not_active Ceased
-
2005
- 2005-12-01 NO NO20055692A patent/NO337485B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR101212631B1 (ko) | 2012-12-14 |
| EP1622639B1 (de) | 2013-01-16 |
| NO20055692D0 (no) | 2005-12-01 |
| EP1622639A2 (de) | 2006-02-08 |
| HRP20050903B1 (hr) | 2013-11-22 |
| PL1622639T3 (pl) | 2013-06-28 |
| HRP20050903A2 (en) | 2006-08-31 |
| WO2004096268A2 (de) | 2004-11-11 |
| KR20060020616A (ko) | 2006-03-06 |
| CA2524573A1 (en) | 2004-11-11 |
| NZ543367A (en) | 2010-06-25 |
| WO2004096268A3 (de) | 2005-04-21 |
| NO337485B1 (no) | 2016-04-25 |
| NO20055692L (no) | 2006-01-30 |
| JP2006525270A (ja) | 2006-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: H. LUNDBECK A/S. (DK) |
|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B25E | Requested change of name of applicant rejected |
Owner name: H. LUNDBECK A/S. (DK) |
|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |