HRP20050362B1 - 3-fenil supstituirani piridoindolon, njegovo dobivanje i njegova terapijska upotreba - Google Patents

3-fenil supstituirani piridoindolon, njegovo dobivanje i njegova terapijska upotreba

Info

Publication number
HRP20050362B1
HRP20050362B1 HRP20050362AA HRP20050362A HRP20050362B1 HR P20050362 B1 HRP20050362 B1 HR P20050362B1 HR P20050362A A HRP20050362A A HR P20050362AA HR P20050362 A HRP20050362 A HR P20050362A HR P20050362 B1 HRP20050362 B1 HR P20050362B1
Authority
HR
Croatia
Prior art keywords
group
phenyl
conrr
phenyl substituted
preparation
Prior art date
Application number
HRP20050362AA
Other languages
English (en)
Croatian (hr)
Inventor
Bernard Bourrie
Pierre Casellas
Paola Ciapetti
Jena-Marie Derocq
Samir Jegham
Yvette Muneaux
Camille-Georges Wermuth
Original Assignee
Sanofi-Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Aventis filed Critical Sanofi-Aventis
Publication of HRP20050362A2 publication Critical patent/HRP20050362A2/hr
Publication of HRP20050362B1 publication Critical patent/HRP20050362B1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HRP20050362AA 2002-10-23 2003-10-21 3-fenil supstituirani piridoindolon, njegovo dobivanje i njegova terapijska upotreba HRP20050362B1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0213264A FR2846329B1 (fr) 2002-10-23 2002-10-23 Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
PCT/FR2003/003110 WO2004041817A1 (fr) 2002-10-23 2003-10-21 Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique.

Publications (2)

Publication Number Publication Date
HRP20050362A2 HRP20050362A2 (en) 2005-12-31
HRP20050362B1 true HRP20050362B1 (hr) 2014-01-31

Family

ID=32088223

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20050362AA HRP20050362B1 (hr) 2002-10-23 2003-10-21 3-fenil supstituirani piridoindolon, njegovo dobivanje i njegova terapijska upotreba

Country Status (32)

Country Link
US (2) US7390818B2 (enExample)
EP (1) EP1556382B1 (enExample)
JP (1) JP4488899B2 (enExample)
KR (1) KR101051859B1 (enExample)
CN (1) CN100345850C (enExample)
AR (1) AR041689A1 (enExample)
AT (1) ATE396994T1 (enExample)
AU (1) AU2003296769B2 (enExample)
BR (1) BR0314883A (enExample)
CA (1) CA2502769C (enExample)
CY (1) CY1109785T1 (enExample)
DE (1) DE60321372D1 (enExample)
DK (1) DK1556382T3 (enExample)
EA (1) EA010833B1 (enExample)
ES (1) ES2304546T3 (enExample)
FR (1) FR2846329B1 (enExample)
HR (1) HRP20050362B1 (enExample)
IL (1) IL168133A (enExample)
IS (1) IS2641B (enExample)
MA (1) MA27455A1 (enExample)
ME (1) ME00102B (enExample)
MX (1) MXPA05004349A (enExample)
NO (1) NO331297B1 (enExample)
NZ (1) NZ539866A (enExample)
PL (1) PL214867B1 (enExample)
PT (1) PT1556382E (enExample)
RS (1) RS51605B (enExample)
SI (1) SI1556382T1 (enExample)
TW (1) TWI325864B (enExample)
UA (1) UA79317C2 (enExample)
WO (1) WO2004041817A1 (enExample)
ZA (1) ZA200503231B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2823975B1 (fr) 2001-04-27 2003-05-30 Sanofi Synthelabo Nouvelle utilisation de pyridoindolone
US7456193B2 (en) 2002-10-23 2008-11-25 Sanofi-Aventis Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
US20100297252A1 (en) 2003-03-03 2010-11-25 Elan Pharma International Ltd. Nanoparticulate meloxicam formulations
US8512727B2 (en) * 2003-03-03 2013-08-20 Alkermes Pharma Ireland Limited Nanoparticulate meloxicam formulations
FR2869316B1 (fr) * 2004-04-21 2006-06-02 Sanofi Synthelabo Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2876377B1 (fr) * 2004-10-11 2007-03-16 Univ Claude Bernard Lyon Nouveaux derives de 9h-pyrido[2,3-b]indole, leur procede de preparation, ainsi que les compositions pharmaceutiques contenant de tels composes
FR2892416B1 (fr) * 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique
FR2945950A1 (fr) 2009-05-27 2010-12-03 Elan Pharma Int Ltd Compositions de nanoparticules anticancereuses et procedes pour les preparer
FR2959133A1 (fr) 2010-04-22 2011-10-28 Sanofi Aventis Formulation pharmaceutique anticancereuse
HUE032426T2 (en) 2009-05-27 2017-09-28 Alkermes Pharma Ireland Ltd Inhibition of flake aggregation in nanoparticulate meloxicam formulations
CN107459481A (zh) * 2017-07-25 2017-12-12 广州大学 一种3‑（4‑甲氧基苯基）‑6‑甲氧基‑4‑氯‑5,7‑二溴喹啉的合成方法
EP3919492A4 (en) * 2019-02-01 2022-11-09 Medshine Discovery Inc. TRICYCLIC COMPOUND CONTAINING PYRIMIDINYL GROUP AS C-MET INHIBITOR
CN113329276B (zh) 2020-02-28 2022-10-28 华为技术有限公司 数据传输方法、装置、网关、芯片及存储介质
CN116171156B (zh) * 2020-07-31 2025-07-04 江苏奥赛康药业有限公司 含嘧啶基团的三并环类化合物的盐型、晶型及其制备方法
US20240132446A1 (en) * 2021-05-26 2024-04-25 Refined Technologies, Inc. Compositions and methods for removal of n-methyl-2-pyrrolidone (nmp) degradation products and other foulants from nmp purification systems

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001009129A2 (en) * 1999-08-03 2001-02-08 Novuspharma S.P.A. 1h-pirido[3, 4-b]indol-1-one derivatives
WO2002087574A2 (fr) * 2001-04-27 2002-11-07 Sanofi-Synthelabo Utilisation de derives de pyridoindolone pour la preparation de medicaments anticancereux

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268772A (en) 1968-03-15 1972-03-29 Glaxo Lab Ltd NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME
US4263304A (en) * 1978-06-05 1981-04-21 Sumitomo Chemical Company, Limited 7 H-indolo[2,3-c]isoquinolines
SU833971A1 (ru) 1979-07-10 1981-05-30 Ленинградский Химико-Фармацевтическийинститут Способ получени 3-фенил-2-оксо- - КАРбОлиНОВ
FR2595701B1 (fr) * 1986-03-17 1988-07-01 Sanofi Sa Derives du pyrido-indole, leur application a titre de medicaments et les compositions les renfermant
JPH10501686A (ja) 1994-04-13 1998-02-17 ザ ロックフェラー ユニヴァーシティ 神経系の細胞へのｄｎａのａａｖ仲介送達
DE19502753A1 (de) * 1995-01-23 1996-07-25 Schering Ag Neue 9H-Pyrido[3,4-b]indol-Derivate
FR2765582B1 (fr) 1997-07-03 1999-08-06 Synthelabo Derives de 3-alkyl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one leur preparation et leur application en therapeutique
FR2765581B1 (fr) * 1997-07-03 1999-08-06 Synthelabo Derives de 3-aryl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one, leur preparation et leur application en therapeutique
CA2326319A1 (en) 1998-04-02 1999-10-14 Neurogen Corporation Aminoalkyl substituted 5,6,7,8-tetrahydro-9h pyrimidino[2,3-b]indole and 5,6,7,8-tetrahydro-9h-pyrimidino[4,5-b]indole derivatives: crf1 specific ligands
US20020156016A1 (en) 2001-03-30 2002-10-24 Gerald Minuk Control of cell growth by altering cell membrane potentials
FR2846330B1 (fr) 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par groupe heterocyclique, leur preparation et leur application en therapeutique
US7456193B2 (en) * 2002-10-23 2008-11-25 Sanofi-Aventis Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
FR2869316B1 (fr) 2004-04-21 2006-06-02 Sanofi Synthelabo Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2892416B1 (fr) 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001009129A2 (en) * 1999-08-03 2001-02-08 Novuspharma S.P.A. 1h-pirido[3, 4-b]indol-1-one derivatives
WO2002087574A2 (fr) * 2001-04-27 2002-11-07 Sanofi-Synthelabo Utilisation de derives de pyridoindolone pour la preparation de medicaments anticancereux

Also Published As

Publication number Publication date
DK1556382T3 (da) 2008-10-06
NZ539866A (en) 2008-01-31
BR0314883A (pt) 2005-08-02
NO20051983L (no) 2005-07-22
EA010833B1 (ru) 2008-12-30
UA79317C2 (en) 2007-06-11
FR2846329B1 (fr) 2004-12-03
CN100345850C (zh) 2007-10-31
IS7815A (is) 2005-04-20
ATE396994T1 (de) 2008-06-15
US20080214538A1 (en) 2008-09-04
DE60321372D1 (de) 2008-07-10
MA27455A1 (fr) 2005-07-01
PL214867B1 (pl) 2013-09-30
ES2304546T3 (es) 2008-10-16
ZA200503231B (en) 2006-06-28
ME00102B (me) 2010-10-10
EP1556382B1 (fr) 2008-05-28
CA2502769C (en) 2011-03-15
EP1556382A1 (fr) 2005-07-27
AR041689A1 (es) 2005-05-26
PL376790A1 (pl) 2006-01-09
MEP22208A (en) 2010-06-10
NO20051983D0 (no) 2005-04-22
NO331297B1 (no) 2011-11-21
EA200500521A1 (ru) 2005-12-29
WO2004041817A1 (fr) 2004-05-21
SI1556382T1 (sl) 2008-10-31
US7390818B2 (en) 2008-06-24
CA2502769A1 (en) 2004-05-21
CN1729190A (zh) 2006-02-01
JP2006511498A (ja) 2006-04-06
FR2846329A1 (fr) 2004-04-30
IS2641B (is) 2010-08-15
KR101051859B1 (ko) 2011-07-25
US20050288318A1 (en) 2005-12-29
JP4488899B2 (ja) 2010-06-23
HK1074446A1 (zh) 2005-11-11
CY1109785T1 (el) 2014-09-10
KR20050086421A (ko) 2005-08-30
RS20050362A (sr) 2007-11-15
IL168133A (en) 2010-05-31
PT1556382E (pt) 2008-07-09
MXPA05004349A (es) 2005-08-26
TWI325864B (en) 2010-06-11
AU2003296769A1 (en) 2004-06-07
US8012991B2 (en) 2011-09-06
HRP20050362A2 (en) 2005-12-31
TW200413368A (en) 2004-08-01
AU2003296769B2 (en) 2010-02-04
RS51605B (sr) 2011-08-31

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Payment date: 20130910

Year of fee payment: 11

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Effective date: 20141021