DE60321372D1 - 3-phenylpyridoindolderivate, ihre herstellung und verwendung - Google Patents

3-phenylpyridoindolderivate, ihre herstellung und verwendung

Info

Publication number
DE60321372D1
DE60321372D1 DE60321372T DE60321372T DE60321372D1 DE 60321372 D1 DE60321372 D1 DE 60321372D1 DE 60321372 T DE60321372 T DE 60321372T DE 60321372 T DE60321372 T DE 60321372T DE 60321372 D1 DE60321372 D1 DE 60321372D1
Authority
DE
Germany
Prior art keywords
phenylpyridoindol
derivatives
preparation
phenylpyridoindol derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60321372T
Other languages
German (de)
English (en)
Inventor
Bernard Bourrie
Pierre Casellas
Paola Ciapetti
Jean-Marie Derocq
Samir Jegham
Yvette Muneaux
Camille-Georges Wermuth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Application granted granted Critical
Publication of DE60321372D1 publication Critical patent/DE60321372D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60321372T 2002-10-23 2003-10-21 3-phenylpyridoindolderivate, ihre herstellung und verwendung Expired - Lifetime DE60321372D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0213264A FR2846329B1 (fr) 2002-10-23 2002-10-23 Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
PCT/FR2003/003110 WO2004041817A1 (fr) 2002-10-23 2003-10-21 Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
DE60321372D1 true DE60321372D1 (de) 2008-07-10

Family

ID=32088223

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60321372T Expired - Lifetime DE60321372D1 (de) 2002-10-23 2003-10-21 3-phenylpyridoindolderivate, ihre herstellung und verwendung

Country Status (32)

Country Link
US (2) US7390818B2 (enExample)
EP (1) EP1556382B1 (enExample)
JP (1) JP4488899B2 (enExample)
KR (1) KR101051859B1 (enExample)
CN (1) CN100345850C (enExample)
AR (1) AR041689A1 (enExample)
AT (1) ATE396994T1 (enExample)
AU (1) AU2003296769B2 (enExample)
BR (1) BR0314883A (enExample)
CA (1) CA2502769C (enExample)
CY (1) CY1109785T1 (enExample)
DE (1) DE60321372D1 (enExample)
DK (1) DK1556382T3 (enExample)
EA (1) EA010833B1 (enExample)
ES (1) ES2304546T3 (enExample)
FR (1) FR2846329B1 (enExample)
HR (1) HRP20050362B1 (enExample)
IL (1) IL168133A (enExample)
IS (1) IS2641B (enExample)
MA (1) MA27455A1 (enExample)
ME (1) ME00102B (enExample)
MX (1) MXPA05004349A (enExample)
NO (1) NO331297B1 (enExample)
NZ (1) NZ539866A (enExample)
PL (1) PL214867B1 (enExample)
PT (1) PT1556382E (enExample)
RS (1) RS51605B (enExample)
SI (1) SI1556382T1 (enExample)
TW (1) TWI325864B (enExample)
UA (1) UA79317C2 (enExample)
WO (1) WO2004041817A1 (enExample)
ZA (1) ZA200503231B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2823975B1 (fr) 2001-04-27 2003-05-30 Sanofi Synthelabo Nouvelle utilisation de pyridoindolone
US7456193B2 (en) 2002-10-23 2008-11-25 Sanofi-Aventis Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
US20100297252A1 (en) * 2003-03-03 2010-11-25 Elan Pharma International Ltd. Nanoparticulate meloxicam formulations
US8512727B2 (en) * 2003-03-03 2013-08-20 Alkermes Pharma Ireland Limited Nanoparticulate meloxicam formulations
FR2869316B1 (fr) 2004-04-21 2006-06-02 Sanofi Synthelabo Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2876377B1 (fr) * 2004-10-11 2007-03-16 Univ Claude Bernard Lyon Nouveaux derives de 9h-pyrido[2,3-b]indole, leur procede de preparation, ainsi que les compositions pharmaceutiques contenant de tels composes
FR2892416B1 (fr) * 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique
FR2959133A1 (fr) 2010-04-22 2011-10-28 Sanofi Aventis Formulation pharmaceutique anticancereuse
FR2945950A1 (fr) 2009-05-27 2010-12-03 Elan Pharma Int Ltd Compositions de nanoparticules anticancereuses et procedes pour les preparer
EP3167875A1 (en) 2009-05-27 2017-05-17 Alkermes Pharma Ireland Limited Reduction of flake-like aggregation in nanoparticulate meloxicam compositions
CN107459481A (zh) * 2017-07-25 2017-12-12 广州大学 一种3‑(4‑甲氧基苯基)‑6‑甲氧基‑4‑氯‑5,7‑二溴喹啉的合成方法
WO2020156453A1 (zh) * 2019-02-01 2020-08-06 南京明德新药研发有限公司 作为c-Met抑制剂的含嘧啶基团的三并环类化合物
CN113329276B (zh) 2020-02-28 2022-10-28 华为技术有限公司 数据传输方法、装置、网关、芯片及存储介质
CN116171156B (zh) * 2020-07-31 2025-07-04 江苏奥赛康药业有限公司 含嘧啶基团的三并环类化合物的盐型、晶型及其制备方法
US20240132446A1 (en) * 2021-05-26 2024-04-25 Refined Technologies, Inc. Compositions and methods for removal of n-methyl-2-pyrrolidone (nmp) degradation products and other foulants from nmp purification systems

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268772A (en) 1968-03-15 1972-03-29 Glaxo Lab Ltd NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME
US4263304A (en) 1978-06-05 1981-04-21 Sumitomo Chemical Company, Limited 7 H-indolo[2,3-c]isoquinolines
SU833971A1 (ru) 1979-07-10 1981-05-30 Ленинградский Химико-Фармацевтическийинститут Способ получени 3-фенил-2-оксо- - КАРбОлиНОВ
FR2595701B1 (fr) 1986-03-17 1988-07-01 Sanofi Sa Derives du pyrido-indole, leur application a titre de medicaments et les compositions les renfermant
EP0755454B1 (en) 1994-04-13 2008-02-13 The Rockefeller University Aav-mediated delivery of dna to cells of the nervous system
DE19502753A1 (de) * 1995-01-23 1996-07-25 Schering Ag Neue 9H-Pyrido[3,4-b]indol-Derivate
FR2765582B1 (fr) 1997-07-03 1999-08-06 Synthelabo Derives de 3-alkyl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one leur preparation et leur application en therapeutique
FR2765581B1 (fr) * 1997-07-03 1999-08-06 Synthelabo Derives de 3-aryl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one, leur preparation et leur application en therapeutique
JP2002510686A (ja) 1998-04-02 2002-04-09 ニューロゲン コーポレイション アミノアルキルで置換された5,6,7,8−テトラヒドロ−9H−ピリジノ[2,3−b]インドール及び5,6,7,8−テトラヒドロ−9Hピリミジノ[4,5−B]インドール誘導体:CRF1特異的配位子
IT1313592B1 (it) * 1999-08-03 2002-09-09 Novuspharma Spa Derivati di 1h-pirido 3,4-b indol-1-one.
US20020156016A1 (en) 2001-03-30 2002-10-24 Gerald Minuk Control of cell growth by altering cell membrane potentials
FR2823975B1 (fr) 2001-04-27 2003-05-30 Sanofi Synthelabo Nouvelle utilisation de pyridoindolone
FR2846330B1 (fr) 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par groupe heterocyclique, leur preparation et leur application en therapeutique
US7456193B2 (en) 2002-10-23 2008-11-25 Sanofi-Aventis Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
FR2869316B1 (fr) 2004-04-21 2006-06-02 Sanofi Synthelabo Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2892416B1 (fr) 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
AU2003296769B2 (en) 2010-02-04
MA27455A1 (fr) 2005-07-01
US7390818B2 (en) 2008-06-24
MEP22208A (en) 2010-06-10
RS20050362A (sr) 2007-11-15
UA79317C2 (en) 2007-06-11
ES2304546T3 (es) 2008-10-16
HRP20050362B1 (hr) 2014-01-31
JP4488899B2 (ja) 2010-06-23
NO331297B1 (no) 2011-11-21
US8012991B2 (en) 2011-09-06
PL376790A1 (pl) 2006-01-09
PT1556382E (pt) 2008-07-09
IS2641B (is) 2010-08-15
EA010833B1 (ru) 2008-12-30
TWI325864B (en) 2010-06-11
MXPA05004349A (es) 2005-08-26
AU2003296769A1 (en) 2004-06-07
WO2004041817A1 (fr) 2004-05-21
CN100345850C (zh) 2007-10-31
EP1556382B1 (fr) 2008-05-28
CA2502769A1 (en) 2004-05-21
IS7815A (is) 2005-04-20
SI1556382T1 (sl) 2008-10-31
RS51605B (sr) 2011-08-31
JP2006511498A (ja) 2006-04-06
HK1074446A1 (zh) 2005-11-11
EA200500521A1 (ru) 2005-12-29
FR2846329A1 (fr) 2004-04-30
AR041689A1 (es) 2005-05-26
HRP20050362A2 (en) 2005-12-31
DK1556382T3 (da) 2008-10-06
US20080214538A1 (en) 2008-09-04
KR101051859B1 (ko) 2011-07-25
EP1556382A1 (fr) 2005-07-27
TW200413368A (en) 2004-08-01
CY1109785T1 (el) 2014-09-10
IL168133A (en) 2010-05-31
FR2846329B1 (fr) 2004-12-03
ATE396994T1 (de) 2008-06-15
NO20051983D0 (no) 2005-04-22
CN1729190A (zh) 2006-02-01
CA2502769C (en) 2011-03-15
NO20051983L (no) 2005-07-22
ZA200503231B (en) 2006-06-28
KR20050086421A (ko) 2005-08-30
ME00102B (me) 2010-10-10
PL214867B1 (pl) 2013-09-30
BR0314883A (pt) 2005-08-02
NZ539866A (en) 2008-01-31
US20050288318A1 (en) 2005-12-29

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