ATE533768T1 - Imidazol-derivate, ihre herstellung und ihre verwendung - Google Patents

Imidazol-derivate, ihre herstellung und ihre verwendung

Info

Publication number
ATE533768T1
ATE533768T1 AT05077705T AT05077705T ATE533768T1 AT E533768 T1 ATE533768 T1 AT E533768T1 AT 05077705 T AT05077705 T AT 05077705T AT 05077705 T AT05077705 T AT 05077705T AT E533768 T1 ATE533768 T1 AT E533768T1
Authority
AT
Austria
Prior art keywords
production
imidazole derivatives
imidazole
derivatives
Prior art date
Application number
AT05077705T
Other languages
English (en)
Inventor
Akihiro Tasaka
Takenori Hitaka
Nobuyuki Matsunaga
Masami Kusaka
Mari Adachi
Isao Aoki
Akio Ojida
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Application granted granted Critical
Publication of ATE533768T1 publication Critical patent/ATE533768T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
AT05077705T 2000-11-17 2001-11-16 Imidazol-derivate, ihre herstellung und ihre verwendung ATE533768T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000351780 2000-11-17
JP2001247618 2001-08-17
JP2001336880 2001-11-01

Publications (1)

Publication Number Publication Date
ATE533768T1 true ATE533768T1 (de) 2011-12-15

Family

ID=27345219

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01982800T ATE327237T1 (de) 2000-11-17 2001-11-16 Imidazol derivate, ihre herstellung und ihre verwendung
AT05077705T ATE533768T1 (de) 2000-11-17 2001-11-16 Imidazol-derivate, ihre herstellung und ihre verwendung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT01982800T ATE327237T1 (de) 2000-11-17 2001-11-16 Imidazol derivate, ihre herstellung und ihre verwendung

Country Status (27)

Country Link
US (1) US7141598B2 (de)
EP (2) EP1334106B1 (de)
JP (2) JP3753971B2 (de)
KR (3) KR100809899B1 (de)
CN (3) CN1329394C (de)
AR (1) AR034854A1 (de)
AT (2) ATE327237T1 (de)
AU (3) AU1429602A (de)
BR (1) BR0115306B1 (de)
CA (1) CA2429133C (de)
CY (1) CY1105423T1 (de)
DE (1) DE60119963T2 (de)
DK (1) DK1334106T3 (de)
ES (1) ES2260303T3 (de)
HK (1) HK1056168A1 (de)
HU (1) HU229408B1 (de)
IL (2) IL155624A0 (de)
MX (1) MXPA03004347A (de)
MY (1) MY134929A (de)
NO (1) NO326366B1 (de)
NZ (1) NZ526387A (de)
PE (1) PE20020596A1 (de)
PL (1) PL204934B1 (de)
PT (1) PT1334106E (de)
SI (1) SI1334106T1 (de)
TW (1) TWI306099B (de)
WO (1) WO2002040484A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003059889A1 (fr) * 2002-01-10 2003-07-24 Takeda Chemical Industries, Ltd. Procede relatif a l'elaboration de compose d'imidazole fondu, reactif de reformatsky sous forme stable, et procede d'elaboration correspondant
WO2004075890A1 (ja) * 2003-02-26 2004-09-10 Takeda Pharmaceutical Company 安定化されたイミダゾール誘導体含有医薬組成物、イミダゾ－ル誘導体の安定化方法
JP4745616B2 (ja) * 2003-02-26 2011-08-10 武田薬品工業株式会社 安定化されたイミダゾール誘導体含有医薬組成物、イミダゾール誘導体の安定化方法
JP4837895B2 (ja) * 2003-03-17 2011-12-14 武田薬品工業株式会社 放出制御組成物
EP1607092A4 (de) * 2003-03-17 2010-12-15 Takeda Pharmaceutical Zusammensetzungen mit kontrollierter freisetzung
WO2005111028A1 (en) * 2004-05-03 2005-11-24 Janssen Pharmaceutica N.V. Novel indole derivatives as selective androgen receptor modulators (sarms)
AR049125A1 (es) * 2004-05-28 2006-06-28 Speedel Experimenta Ag Heterociclos biciclicos nitrogenados inhibidores de la aromatasa.
EP1854463A4 (de) * 2005-03-03 2011-03-23 Takeda Pharmaceutical Zusammensetzung mit kontrollierter freisetzung
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
TW200804378A (en) * 2005-12-09 2008-01-16 Speedel Experimenta Ag Organic compounds
JP5230448B2 (ja) * 2006-02-10 2013-07-10 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 選択的アンドローゲン受容体モジュレーターとして有用な新イミダゾロピラゾール誘導体
AR060225A1 (es) * 2006-03-31 2008-06-04 Speedel Experimenta Ag Proceso para preparar 6,7- dihidro-5h-imidazo (1,5-a) piridin -8- ona
AU2008319767B8 (en) * 2007-10-29 2014-01-09 Takeda Pharmaceutical Company Limited Pyrrolo [1,2-C] imidazole derivatives for use in the prophylaxis or treatment of cancer which is refractory to known cancer therapies
JOP20190231A1 (ar) * 2009-01-15 2017-06-16 Incyte Corp طرق لاصلاح مثبطات انزيم jak و المركبات الوسيطة المتعلقة به
UY33740A (es) * 2010-11-18 2012-05-31 Takeda Pharmaceutical Método para tratar el cáncer de mama y cáncer de ovarios
ES2607070T3 (es) 2011-04-01 2017-03-29 Takeda Pharmaceutical Company Limited Preparación sólida
EA201490019A1 (ru) 2011-06-15 2014-04-30 Такеда Фармасьютикал Компани Лимитед Способ получения производных имидазола

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728645A (en) * 1982-12-21 1988-03-01 Ciba-Geigy Corporation Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors
NZ221729A (en) 1986-09-15 1989-07-27 Janssen Pharmaceutica Nv Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions
NZ224288A (en) 1987-04-22 1989-12-21 Merrell Dow Pharma 17b-(cyclopropylamino)androst-5-en-3b-ol and related compounds and methods using these for treatment of non-humans
US5057521A (en) * 1988-10-26 1991-10-15 Ciba-Geigy Corporation Use of bicyclic imidazole compounds for the treatment of hyperaldosteronism
US4966898A (en) 1989-08-15 1990-10-30 Merrell Dow Pharmaceuticals Inc. 4-substituted 17β-(cyclopropylamino)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors
CA2104234A1 (en) 1991-03-01 1993-07-22 Denis R. Mckay Powder coating method for producing circuit board laminae and the like
ES2161714T3 (es) * 1992-01-27 2001-12-16 Janssen Pharmaceutica Nv Derivados de 1h-bencimidazol sustituidos por pirroloimidazolilo e imidazopiridinilo como inhibidores de aromatasa.
US5457102A (en) 1994-07-07 1995-10-10 Janssen Pharmaceutica, N.V. Pyrroloimidazolyl and imidazopyridinyl substituted 1H-benzimidazole derivatives
EP0633893B1 (de) 1992-03-31 1999-11-24 Btg International Limited 17-substituierte steroide, verwendbar bei behandlung von krebs
GB9310635D0 (en) 1993-05-21 1993-07-07 Glaxo Group Ltd Chemical compounds
US5807880A (en) 1993-09-30 1998-09-15 Yamanouchi Pharmaceutical Co., Ltd. Azole derivative and pharmaceutical composition thereof
WO1996014090A1 (en) 1994-11-07 1996-05-17 Janssen Pharmaceutica N.V. Compositions comprising carbazoles and cyclodextrins
AU6015796A (en) 1995-06-14 1997-01-15 Yamanouchi Pharmaceutical Co., Ltd. Fused imidazole derivatives and medicinal composition thereof
DE69810760T2 (de) 1997-02-21 2003-11-20 Takeda Chemical Industries Ltd Verbindungen mit kondensierten ringen, verfahren zu ihrer herstellung und ihre anwendung
EP1028110B1 (de) 1997-10-02 2004-04-14 Daiichi Pharmaceutical Co., Ltd. Dihydronaphthalinderivate und verfahren zur herstellung derselben
ATE293102T1 (de) 1998-04-23 2005-04-15 Takeda Pharmaceutical Naphthalene derivate ,ihre herstellung und verwendung
PE20010781A1 (es) * 1999-10-22 2001-08-08 Takeda Chemical Industries Ltd Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion

Also Published As

Publication number Publication date
KR20050105287A (ko) 2005-11-03
HUP0400549A2 (hu) 2004-06-28
AU2002214296C1 (en) 2006-04-13
DE60119963T2 (de) 2006-10-05
HU229408B1 (hu) 2013-12-30
DE60119963D1 (de) 2006-06-29
NO326366B1 (no) 2008-11-17
EP1681290A2 (de) 2006-07-19
EP1681290A3 (de) 2006-07-26
PE20020596A1 (es) 2002-08-13
IL155624A0 (en) 2003-11-23
AU1429602A (en) 2002-05-27
IL155624A (en) 2006-12-31
JP2006045239A (ja) 2006-02-16
KR20030048156A (ko) 2003-06-18
KR100809899B1 (ko) 2008-03-10
WO2002040484A3 (en) 2002-09-26
KR20080002929A (ko) 2008-01-04
CN1329394C (zh) 2007-08-01
AU2005225035B2 (en) 2007-02-22
CY1105423T1 (el) 2010-04-28
PL204934B1 (pl) 2010-02-26
CN1474819A (zh) 2004-02-11
NO20032234L (no) 2003-07-16
NO20032234D0 (no) 2003-05-16
MXPA03004347A (es) 2004-05-04
AU2005225035A1 (en) 2005-11-10
CA2429133A1 (en) 2002-05-23
HK1056168A1 (en) 2004-02-06
KR100725442B1 (ko) 2007-06-07
PT1334106E (pt) 2006-08-31
EP1334106B1 (de) 2006-05-24
EP1334106A2 (de) 2003-08-13
EP1681290B1 (de) 2011-11-16
MY134929A (en) 2008-01-31
TWI306099B (en) 2009-02-11
CN1900079A (zh) 2007-01-24
JP2003201282A (ja) 2003-07-18
US7141598B2 (en) 2006-11-28
CN100572363C (zh) 2009-12-23
DK1334106T3 (da) 2006-09-18
ATE327237T1 (de) 2006-06-15
PL362766A1 (en) 2004-11-02
JP3753971B2 (ja) 2006-03-08
US20040033935A1 (en) 2004-02-19
AR034854A1 (es) 2004-03-24
JP4427496B2 (ja) 2010-03-10
HUP0400549A3 (en) 2004-09-28
CA2429133C (en) 2009-08-18
NZ526387A (en) 2004-02-27
BR0115306B1 (pt) 2013-12-24
WO2002040484A2 (en) 2002-05-23
EP1681290B9 (de) 2013-06-19
CN1680336A (zh) 2005-10-12
BR0115306A (pt) 2004-02-10
ES2260303T3 (es) 2006-11-01
AU2002214296B2 (en) 2005-09-29
SI1334106T1 (sl) 2006-10-31

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