HRP20040409A2 - 4-(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidone derivatives as pde-4 inhibitors for the treatment of neurological syndromes - Google Patents

4-(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidone derivatives as pde-4 inhibitors for the treatment of neurological syndromes Download PDF

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Publication number
HRP20040409A2
HRP20040409A2 HR20040409A HRP20040409A HRP20040409A2 HR P20040409 A2 HRP20040409 A2 HR P20040409A2 HR 20040409 A HR20040409 A HR 20040409A HR P20040409 A HRP20040409 A HR P20040409A HR P20040409 A2 HRP20040409 A2 HR P20040409A2
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Croatia
Prior art keywords
alkyl
substituted
halogen
combinations
carbon atoms
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HR20040409A
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English (en)
Croatian (hr)
Inventor
Liu Ruiping
De Vivo Michael
Ernst Hess Hans-Jurgen
Allen
Keuster Erik
Theim Ashok
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Memory Pharmaceuticals Corporation
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Publication of HRP20040409A2 publication Critical patent/HRP20040409A2/hr

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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D207/24—Oxygen or sulfur atoms
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HR20040409A 2001-10-16 2004-05-07 4-(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidone derivatives as pde-4 inhibitors for the treatment of neurological syndromes HRP20040409A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32931401P 2001-10-16 2001-10-16
PCT/US2002/032834 WO2003032981A1 (en) 2001-10-16 2002-10-16 4-(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidone derivatives as pde-4 inhibitors for the treatment of neurological syndromes

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HRP20040409A2 true HRP20040409A2 (en) 2005-06-30

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HR20040409A HRP20040409A2 (en) 2001-10-16 2004-05-07 4-(4-alkoxy-3-hydroxyphenyl)-2-pyrrolidone derivatives as pde-4 inhibitors for the treatment of neurological syndromes

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US (3) US7235579B2 (es)
EP (1) EP1435944B1 (es)
JP (2) JP4484515B2 (es)
KR (2) KR100951218B1 (es)
CN (1) CN1604776A (es)
AT (1) ATE444065T1 (es)
AU (1) AU2002335015B8 (es)
BR (1) BR0213660A (es)
CA (1) CA2463469A1 (es)
CO (1) CO5570674A2 (es)
DE (1) DE60233884D1 (es)
ES (1) ES2334650T3 (es)
HR (1) HRP20040409A2 (es)
IL (1) IL161317A0 (es)
MX (1) MXPA04003516A (es)
NO (1) NO20042024L (es)
NZ (1) NZ532288A (es)
RU (2) RU2340600C2 (es)
WO (1) WO2003032981A1 (es)
ZA (1) ZA200402856B (es)

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