HRP20030388A2 - Use of antiprogestins for the induction of apoptosis in a cell - Google Patents

Use of antiprogestins for the induction of apoptosis in a cell Download PDF

Info

Publication number
HRP20030388A2
HRP20030388A2 HR20030388A HRP20030388A HRP20030388A2 HR P20030388 A2 HRP20030388 A2 HR P20030388A2 HR 20030388 A HR20030388 A HR 20030388A HR P20030388 A HRP20030388 A HR P20030388A HR P20030388 A2 HRP20030388 A2 HR P20030388A2
Authority
HR
Croatia
Prior art keywords
antiprogestin
cell
tumor
apoptosis
breast cancer
Prior art date
Application number
HR20030388A
Other languages
English (en)
Croatian (hr)
Inventor
Hoffmann Jens
Lichtner Rosemarie
Siemeister Gerhard
Schneider Martin
Fuhrmann Ulrike
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of HRP20030388A2 publication Critical patent/HRP20030388A2/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HR20030388A 2000-10-18 2003-05-14 Use of antiprogestins for the induction of apoptosis in a cell HRP20030388A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24099100P 2000-10-18 2000-10-18
EP00250342 2000-10-18
PCT/EP2001/012006 WO2002032432A1 (en) 2000-10-18 2001-10-17 Use of antiprogestins for the induction of apoptosis in a cell

Publications (1)

Publication Number Publication Date
HRP20030388A2 true HRP20030388A2 (en) 2005-04-30

Family

ID=26072952

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030388A HRP20030388A2 (en) 2000-10-18 2003-05-14 Use of antiprogestins for the induction of apoptosis in a cell

Country Status (29)

Country Link
EP (1) EP1326617B9 (el)
JP (1) JP2004511523A (el)
KR (1) KR100668024B1 (el)
CN (1) CN1209111C (el)
AT (1) ATE334683T1 (el)
AU (2) AU2361902A (el)
BG (1) BG107744A (el)
BR (1) BR0114696A (el)
CA (1) CA2423020C (el)
CY (1) CY1105745T1 (el)
CZ (1) CZ299823B6 (el)
DE (1) DE60121980T2 (el)
DK (1) DK1326617T3 (el)
EA (1) EA010593B1 (el)
EE (1) EE200300157A (el)
ES (1) ES2269492T3 (el)
HK (1) HK1062273A1 (el)
HR (1) HRP20030388A2 (el)
HU (1) HUP0301433A3 (el)
IL (2) IL154976A0 (el)
MX (1) MXPA03002955A (el)
NO (1) NO20031741L (el)
NZ (1) NZ538347A (el)
PL (1) PL360157A1 (el)
PT (1) PT1326617E (el)
SI (1) SI1326617T1 (el)
SK (1) SK4702003A3 (el)
UA (1) UA76729C2 (el)
WO (1) WO2002032432A1 (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY27301A1 (es) * 2001-05-25 2003-02-28 Schering Ag Uso y composiciones de antiprogestinas para el tratamiento de enfermedades de la próstata
US20040242551A1 (en) * 2003-05-28 2004-12-02 Schering Ag Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
WO2008128791A2 (en) * 2007-04-23 2008-10-30 Bayer Schering Pharma Aktiengesellschaft Progesterone-receptor antagonist for use in brca-mediated cancer alone or as combination with antiestrogen
US20080268041A1 (en) * 2007-04-23 2008-10-30 Jens Hoffmann Combination of progesterone-receptor antagonist together with none-steroidal antiestrogen for use in brca mediated diseases
JP2010524996A (ja) * 2007-04-23 2010-07-22 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト Brca媒介性疾患における使用のための、プロゲステロン受容体拮抗薬と、ルテインホルモン放出ホルモン作動薬および拮抗薬との組み合わせ
GB0718167D0 (en) 2007-09-18 2007-10-31 Cancer Rec Tech Ltd Cancer marker and therapeutic target
CN103957920B (zh) * 2011-10-04 2018-04-20 因维维斯制药公司 用于鉴定和治疗抗黄体制剂敏感性肿瘤的方法和系统

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19706061A1 (de) * 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette

Also Published As

Publication number Publication date
ES2269492T3 (es) 2007-04-01
MXPA03002955A (es) 2003-08-07
KR20030057540A (ko) 2003-07-04
KR100668024B1 (ko) 2007-01-15
CN1209111C (zh) 2005-07-06
DE60121980D1 (de) 2006-09-14
EP1326617B9 (en) 2006-10-25
CA2423020A1 (en) 2002-04-25
UA76729C2 (uk) 2006-09-15
CN1469749A (zh) 2004-01-21
EE200300157A (et) 2003-08-15
NO20031741L (no) 2003-06-17
WO2002032432A1 (en) 2002-04-25
CY1105745T1 (el) 2010-12-22
HUP0301433A3 (en) 2010-01-28
CZ299823B6 (cs) 2008-12-03
PT1326617E (pt) 2006-12-29
EP1326617B1 (en) 2006-08-02
ATE334683T1 (de) 2006-08-15
SI1326617T1 (sl) 2007-02-28
DK1326617T3 (da) 2006-12-18
CA2423020C (en) 2009-01-20
BG107744A (bg) 2004-02-27
NZ538347A (en) 2007-03-30
AU2002223619B2 (en) 2006-08-24
JP2004511523A (ja) 2004-04-15
HUP0301433A2 (hu) 2003-10-28
AU2361902A (en) 2002-04-29
IL154976A0 (en) 2003-10-31
BR0114696A (pt) 2003-11-18
HK1062273A1 (en) 2004-10-29
PL360157A1 (en) 2004-09-06
NO20031741D0 (no) 2003-04-15
IL154976A (en) 2007-05-15
DE60121980T2 (de) 2007-03-01
EA010593B1 (ru) 2008-10-30
EP1326617A1 (en) 2003-07-16
EA200300479A1 (ru) 2003-10-30
SK4702003A3 (en) 2004-01-08

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Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
PNAN Change of the applicant name, address/residence

Owner name: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT, DE

ODBI Application refused