HRP20020342A2 - Use of dipyridamole or mopidamol in the manufacture of a medicament for the teatment and prevention of fibrin-dependent microcirculation disorders - Google Patents
Use of dipyridamole or mopidamol in the manufacture of a medicament for the teatment and prevention of fibrin-dependent microcirculation disorders Download PDFInfo
- Publication number
- HRP20020342A2 HRP20020342A2 HR20020342A HRP20020342A HRP20020342A2 HR P20020342 A2 HRP20020342 A2 HR P20020342A2 HR 20020342 A HR20020342 A HR 20020342A HR P20020342 A HRP20020342 A HR P20020342A HR P20020342 A2 HRP20020342 A2 HR P20020342A2
- Authority
- HR
- Croatia
- Prior art keywords
- dipyridamole
- microcirculation
- disease
- pyrimido
- pyrimidine
- Prior art date
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- IZEKFCXSFNUWAM-UHFFFAOYSA-N dipyridamole Chemical compound C=12N=C(N(CCO)CCO)N=C(N3CCCCC3)C2=NC(N(CCO)CCO)=NC=1N1CCCCC1 IZEKFCXSFNUWAM-UHFFFAOYSA-N 0.000 title claims description 62
- 229960002768 dipyridamole Drugs 0.000 title claims description 61
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- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 title claims description 23
- 229950003499 fibrin Drugs 0.000 title claims description 23
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- FOYWNSCCNCUEPU-UHFFFAOYSA-N mopidamol Chemical compound C12=NC(N(CCO)CCO)=NC=C2N=C(N(CCO)CCO)N=C1N1CCCCC1 FOYWNSCCNCUEPU-UHFFFAOYSA-N 0.000 title description 3
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- JOZPEVMCAKXSEY-UHFFFAOYSA-N pyrimido[5,4-d]pyrimidine Chemical compound N1=CN=CC2=NC=NC=C21 JOZPEVMCAKXSEY-UHFFFAOYSA-N 0.000 claims description 14
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99121121A EP1093814A1 (en) | 1999-10-22 | 1999-10-22 | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
Publications (1)
| Publication Number | Publication Date |
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| HRP20020342A2 true HRP20020342A2 (en) | 2003-10-31 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20020342A HRP20020342A2 (en) | 1999-10-22 | 2002-04-18 | Use of dipyridamole or mopidamol in the manufacture of a medicament for the teatment and prevention of fibrin-dependent microcirculation disorders |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US20030149058A1 (sk) |
| EP (2) | EP1093814A1 (sk) |
| JP (1) | JP2003512431A (sk) |
| KR (1) | KR20020040901A (sk) |
| CN (2) | CN1823780A (sk) |
| AR (1) | AR026197A1 (sk) |
| AU (1) | AU784124B2 (sk) |
| BG (1) | BG106609A (sk) |
| BR (1) | BR0014946A (sk) |
| CA (1) | CA2387486C (sk) |
| CZ (1) | CZ20021487A3 (sk) |
| EA (1) | EA200200448A1 (sk) |
| EE (1) | EE200200214A (sk) |
| HK (1) | HK1048597A1 (sk) |
| HR (1) | HRP20020342A2 (sk) |
| HU (1) | HUP0203249A3 (sk) |
| IL (1) | IL148974A0 (sk) |
| MX (1) | MXPA02003901A (sk) |
| NO (1) | NO20021784L (sk) |
| NZ (1) | NZ518525A (sk) |
| PE (1) | PE20010747A1 (sk) |
| PL (1) | PL354591A1 (sk) |
| SK (1) | SK7112002A3 (sk) |
| TR (1) | TR200201089T2 (sk) |
| WO (1) | WO2001030353A1 (sk) |
| YU (1) | YU30002A (sk) |
| ZA (1) | ZA200203156B (sk) |
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| EP1093814A1 (en) * | 1999-10-22 | 2001-04-25 | Boehringer Ingelheim Pharma KG | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
| US7064130B2 (en) * | 2001-04-20 | 2006-06-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders |
| DE10119680A1 (de) * | 2001-04-20 | 2002-11-14 | Boehringer Ingelheim Pharma | Verwendung von Radikalfänger-Verbindungen zur Behandlung und Verhinderung von no-abhängigen Störungen der Mikrozirkulation |
| US7253155B2 (en) | 2001-10-05 | 2007-08-07 | Combinatorx, Inc. | Combinations for the treatment of immunoinflammatory disorders |
| MY131170A (en) | 2002-03-28 | 2007-07-31 | Nissan Chemical Ind Ltd | Therapeutic agent for glomerular disease |
| DE10335027A1 (de) * | 2003-07-31 | 2005-02-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Angiotensin II Rezeptor Antagonisten |
| WO2004069254A2 (en) * | 2003-02-07 | 2004-08-19 | Boehringer Ingelheim International Gmbh | Use of dipyridamole or mopidamole for treatment and prevention of mmp-9-dependent disorders |
| DE10306179A1 (de) * | 2003-02-13 | 2004-08-26 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Dipyridamol in Kombination mit Acetylsalicylsäure und einem Angiotensin II-Antagonisten zur Schlaganfall-Prophylaxe |
| EP1622621A2 (en) * | 2003-04-24 | 2006-02-08 | Boehringer Ingelheim International GmbH | Use of dipyridamole or mopidamole for treatment and prevention of thrombo-embolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of thrombin receptors |
| JP2005060359A (ja) * | 2003-08-13 | 2005-03-10 | Boehringer Ingelheim Pharma Gmbh & Co Kg | 血管系病態の治療及び予防のためのジピリダモール、アセチルサリチル酸及びアンギオテンシンｉｉ拮抗薬の使用 |
| TW200517114A (en) * | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
| KR20070026577A (ko) | 2004-05-13 | 2007-03-08 | 베링거 인겔하임 인터내셔날 게엠베하 | 혈소판 억제제 저항성 치료를 위한 디피리다몰의 용도 |
| ATE493973T1 (de) | 2004-06-04 | 2011-01-15 | Teva Pharma | Irbesartan enthaltende pharmazeutische zusammensetzung |
| EP1820506B1 (en) * | 2006-02-09 | 2008-03-26 | Teva Pharmaceutical Industries Ltd. | Dipyridamole extended-release formulations and process for preparing same |
| WO2008060934A2 (en) * | 2006-11-14 | 2008-05-22 | Acusphere, Inc. | Formulations of tetrahydropyridine antiplatelet agents for parenteral or oral administration |
| EP3607941A1 (en) * | 2013-04-30 | 2020-02-12 | Otitopic Inc. | Dry powder formulations and methods of use |
| TW201503900A (zh) * | 2013-07-29 | 2015-02-01 | ren-zheng Lin | 增強治療急性中風之抗血小板藥物之遞送方法及其組合物 |
| CN115282152A (zh) * | 2015-01-28 | 2022-11-04 | 瑞采生技有限公司 | 用于增强PPARγ表现及核转位之化合物及其医疗用途 |
| KR101736832B1 (ko) | 2017-02-28 | 2017-05-17 | 초당약품공업 주식회사 | 디피리다몰을 유효 성분으로 함유하는 신장 질환 치료용 의약 조성물 |
| CN114432451B (zh) * | 2018-12-21 | 2024-02-09 | 广州市妇女儿童医疗中心 | 胃肠道疾病的免疫机制及治疗药物 |
| CN111346228B (zh) * | 2018-12-21 | 2022-01-14 | 广州市妇女儿童医疗中心 | 胃肠道疾病的免疫机制及治疗药物 |
| CN118477044A (zh) * | 2023-02-13 | 2024-08-13 | 智泽童康(广州)生物科技有限公司 | 一种双嘧达莫的矫味组合物、干混悬剂及其应用 |
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| AU779991B2 (en) * | 1999-08-10 | 2005-02-24 | Board Of Regents, The University Of Texas System | Method for increasing optic nerve, choroidal and retinal blood flow to facilitate the preservation of sight |
| EP1093814A1 (en) * | 1999-10-22 | 2001-04-25 | Boehringer Ingelheim Pharma KG | Use of dipyridamole or mopidamol in the manufacture of a medicament for the treatment and prevention of fibrin-dependent microcirculation disorders |
| DE10011482B4 (de) * | 2000-03-09 | 2004-06-09 | Fresenius Hemocare Gmbh | Verfahren zum Herstellen eines Adsorbens zum Absenken der Konzentration von Fibrinogen und/oder Fibrin, Adsorbens und Verwendung des Adsorbens zur Herstellung eines Adsorbers |
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| EP1622621A2 (en) * | 2003-04-24 | 2006-02-08 | Boehringer Ingelheim International GmbH | Use of dipyridamole or mopidamole for treatment and prevention of thrombo-embolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of thrombin receptors |
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1999
- 1999-10-22 EP EP99121121A patent/EP1093814A1/en not_active Withdrawn
-
2000
- 2000-10-14 CZ CZ20021487A patent/CZ20021487A3/cs unknown
- 2000-10-14 JP JP2001532773A patent/JP2003512431A/ja active Pending
- 2000-10-14 BR BR0014946-2A patent/BR0014946A/pt not_active Expired - Fee Related
- 2000-10-14 PL PL00354591A patent/PL354591A1/xx not_active Application Discontinuation
- 2000-10-14 KR KR1020027005042A patent/KR20020040901A/ko not_active Application Discontinuation
- 2000-10-14 EP EP00974393A patent/EP1225900A1/en not_active Withdrawn
- 2000-10-14 YU YU30002A patent/YU30002A/sh unknown
- 2000-10-14 IL IL14897400A patent/IL148974A0/xx unknown
- 2000-10-14 CA CA002387486A patent/CA2387486C/en not_active Expired - Fee Related
- 2000-10-14 HU HU0203249A patent/HUP0203249A3/hu unknown
- 2000-10-14 CN CNA2005101362547A patent/CN1823780A/zh active Pending
- 2000-10-14 CN CNB008146756A patent/CN100411620C/zh not_active Expired - Fee Related
- 2000-10-14 WO PCT/EP2000/010123 patent/WO2001030353A1/en active IP Right Grant
- 2000-10-14 NZ NZ518525A patent/NZ518525A/en unknown
- 2000-10-14 EE EEP200200214A patent/EE200200214A/xx unknown
- 2000-10-14 AU AU12721/01A patent/AU784124B2/en not_active Ceased
- 2000-10-14 TR TR2002/01089T patent/TR200201089T2/xx unknown
- 2000-10-14 SK SK711-2002A patent/SK7112002A3/sk not_active Application Discontinuation
- 2000-10-14 EA EA200200448A patent/EA200200448A1/ru unknown
- 2000-10-14 MX MXPA02003901A patent/MXPA02003901A/es unknown
- 2000-10-20 AR ARP000105541A patent/AR026197A1/es not_active Suspension/Interruption
- 2000-10-20 PE PE2000001127A patent/PE20010747A1/es not_active Application Discontinuation
-
2002
- 2002-04-12 BG BG106609A patent/BG106609A/bg active Pending
- 2002-04-16 NO NO20021784A patent/NO20021784L/no not_active Application Discontinuation
- 2002-04-18 HR HR20020342A patent/HRP20020342A2/hr not_active Application Discontinuation
- 2002-04-22 ZA ZA200203156A patent/ZA200203156B/xx unknown
-
2003
- 2003-02-06 HK HK03100835.6A patent/HK1048597A1/zh unknown
- 2003-02-27 US US10/376,072 patent/US20030149058A1/en not_active Abandoned
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2007
- 2007-12-18 US US11/958,504 patent/US20080113934A1/en not_active Abandoned
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