HN2002000153A - Formulaciones autoemulsionantes de inhibidores de la proteina de transferencia de colesteril ester. - Google Patents

Formulaciones autoemulsionantes de inhibidores de la proteina de transferencia de colesteril ester.

Info

Publication number
HN2002000153A
HN2002000153A HN2002000153A HN2002000153A HN2002000153A HN 2002000153 A HN2002000153 A HN 2002000153A HN 2002000153 A HN2002000153 A HN 2002000153A HN 2002000153 A HN2002000153 A HN 2002000153A HN 2002000153 A HN2002000153 A HN 2002000153A
Authority
HN
Honduras
Prior art keywords
cholesterile
ester
inhibitors
emulsioning
formulations
Prior art date
Application number
HN2002000153A
Other languages
English (en)
Inventor
Michael Jon Gumkowski
Sharad Balasaheb
Michael Ellis Perlman
Franco LOMBARDO
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of HN2002000153A publication Critical patent/HN2002000153A/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Abstract

ESTA INVENCION SE REFIERE A FORMULACIONES ENCAPSULADAS DE LA PROTEINA DE TRANSFERENCIA DE COLESTERIL ESTER (CETP) PARA USO EN MAMIFEROS, ESPECIALMENTE EN SERES HUMANOS, QUE PROPORCIONAN MAYORES CONCENTRACIONES DE INHIBIDORES DE CETP PARA LA ABSORCION Y, POR LO MTANTO, UNA MAOR BIODISPONIBILIDAD.
HN2002000153A 2001-06-21 2002-06-20 Formulaciones autoemulsionantes de inhibidores de la proteina de transferencia de colesteril ester. HN2002000153A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30002801P 2001-06-21 2001-06-21

Publications (1)

Publication Number Publication Date
HN2002000153A true HN2002000153A (es) 2002-11-05

Family

ID=23157363

Family Applications (1)

Application Number Title Priority Date Filing Date
HN2002000153A HN2002000153A (es) 2001-06-21 2002-06-20 Formulaciones autoemulsionantes de inhibidores de la proteina de transferencia de colesteril ester.

Country Status (33)

Country Link
US (2) US6962931B2 (es)
EP (1) EP1453544A2 (es)
JP (1) JP2005500314A (es)
KR (1) KR20040015746A (es)
CN (1) CN1635911A (es)
AP (1) AP2002002559A0 (es)
AR (1) AR034599A1 (es)
BG (1) BG108486A (es)
BR (1) BR0210505A (es)
CA (1) CA2455288A1 (es)
CR (1) CR7163A (es)
CZ (1) CZ20033341A3 (es)
EA (1) EA200301139A1 (es)
EC (1) ECSP034875A (es)
EE (1) EE200400024A (es)
GT (1) GT200200124A (es)
HN (1) HN2002000153A (es)
HU (1) HUP0400263A2 (es)
IL (1) IL158765A0 (es)
IS (1) IS7014A (es)
MA (1) MA27034A1 (es)
MX (1) MXPA04000014A (es)
NO (1) NO20035632L (es)
OA (1) OA12619A (es)
PA (1) PA8548601A1 (es)
PE (1) PE20030128A1 (es)
PL (1) PL368850A1 (es)
SK (1) SK15172003A3 (es)
SV (1) SV2003001103A (es)
TN (1) TNSN03139A1 (es)
UY (1) UY27344A1 (es)
WO (1) WO2003000295A2 (es)
ZA (1) ZA200308561B (es)

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EE200400024A (et) 2004-06-15
WO2003000295A3 (en) 2004-05-27
US6962931B2 (en) 2005-11-08
HUP0400263A2 (hu) 2005-03-29
SV2003001103A (es) 2003-03-18
TNSN03139A1 (fr) 2005-12-23
CR7163A (es) 2004-02-23
JP2005500314A (ja) 2005-01-06
OA12619A (en) 2006-06-12
ZA200308561B (en) 2004-11-17
SK15172003A3 (en) 2004-11-03
CZ20033341A3 (cs) 2004-10-13
CA2455288A1 (en) 2003-01-03
NO20035632D0 (no) 2003-12-17
BG108486A (bg) 2005-03-31
MXPA04000014A (es) 2004-05-21
CN1635911A (zh) 2005-07-06
PA8548601A1 (es) 2003-09-05
AR034599A1 (es) 2004-03-03
IS7014A (is) 2003-10-31
UY27344A1 (es) 2003-01-31
NO20035632L (no) 2004-02-18
MA27034A1 (fr) 2004-12-20
AP2002002559A0 (en) 2002-06-30
PL368850A1 (en) 2005-04-04
US20030022944A1 (en) 2003-01-30
KR20040015746A (ko) 2004-02-19
IL158765A0 (en) 2004-05-12
GT200200124A (es) 2003-09-22
EP1453544A2 (en) 2004-09-08
PE20030128A1 (es) 2003-02-28
ECSP034875A (es) 2004-01-28
EA200301139A1 (ru) 2004-12-30
WO2003000295A2 (en) 2003-01-03
BR0210505A (pt) 2004-05-18
US20060014788A1 (en) 2006-01-19

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