HK88897A - Polyazamacrocyclic compounds for complexation of metal ions - Google Patents

Polyazamacrocyclic compounds for complexation of metal ions

Info

Publication number
HK88897A
HK88897A HK88897A HK88897A HK88897A HK 88897 A HK88897 A HK 88897A HK 88897 A HK88897 A HK 88897A HK 88897 A HK88897 A HK 88897A HK 88897 A HK88897 A HK 88897A
Authority
HK
Hong Kong
Prior art keywords
complexation
metal ions
polyazamacrocyclic
compound
alkyl
Prior art date
Application number
HK88897A
Other languages
English (en)
Inventor
A Dean Sherry
Istvan Lazar
Erno Brucher
Ravichandran Ramasamy
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/662,075 external-priority patent/US4639365A/en
Application filed by Univ Texas filed Critical Univ Texas
Publication of HK88897A publication Critical patent/HK88897A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Laminated Bodies (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
HK88897A 1984-10-18 1997-06-26 Polyazamacrocyclic compounds for complexation of metal ions HK88897A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/662,075 US4639365A (en) 1984-10-18 1984-10-18 Gadolinium chelates as NMR contrast agents
US07/615,619 US5342606A (en) 1984-10-18 1990-11-19 Polyazamacrocyclic compounds for complexation of metal ions
PCT/US1991/008438 WO1992008725A1 (en) 1984-10-18 1991-11-12 Polyazamacrocyclic compounds for complexation of metal ions

Publications (1)

Publication Number Publication Date
HK88897A true HK88897A (en) 1997-06-27

Family

ID=34922814

Family Applications (1)

Application Number Title Priority Date Filing Date
HK88897A HK88897A (en) 1984-10-18 1997-06-26 Polyazamacrocyclic compounds for complexation of metal ions

Country Status (20)

Country Link
US (1) US5342606A (zh)
JP (1) JP3334717B2 (zh)
CN (2) CN1036717C (zh)
AT (1) ATE144522T1 (zh)
AU (1) AU654987B2 (zh)
CA (1) CA2095615C (zh)
DE (1) DE69122881T2 (zh)
ES (1) ES2093816T3 (zh)
FI (1) FI932231A0 (zh)
HK (1) HK88897A (zh)
HU (1) HUT64768A (zh)
IE (1) IE914001A1 (zh)
IL (1) IL100073A (zh)
MX (1) MX9102116A (zh)
NO (1) NO307380B1 (zh)
NZ (1) NZ240626A (zh)
PT (1) PT99556B (zh)
SG (1) SG48154A1 (zh)
WO (1) WO1992008725A1 (zh)
ZA (1) ZA919127B (zh)

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Also Published As

Publication number Publication date
AU654987B2 (en) 1994-12-01
IE914001A1 (en) 1992-05-20
DE69122881T2 (de) 1997-04-03
CN1066073A (zh) 1992-11-11
CA2095615A1 (en) 1992-05-20
JPH06502645A (ja) 1994-03-24
SG48154A1 (en) 1998-04-17
IL100073A (en) 1997-11-20
AU9077091A (en) 1992-06-11
US5342606A (en) 1994-08-30
WO1992008725A1 (en) 1992-05-29
ZA919127B (en) 1993-05-18
NO931793D0 (no) 1993-05-18
CN1036717C (zh) 1997-12-17
MX9102116A (es) 1992-06-01
NO307380B1 (no) 2000-03-27
FI932231A (fi) 1993-05-17
PT99556A (pt) 1992-10-30
NO931793L (no) 1993-05-18
IL100073A0 (en) 1992-08-18
DE69122881D1 (de) 1996-11-28
ES2093816T3 (es) 1997-01-01
PT99556B (pt) 1999-04-30
CA2095615C (en) 2003-07-08
NZ240626A (en) 1994-11-25
FI932231A0 (fi) 1993-05-17
CN1193625A (zh) 1998-09-23
JP3334717B2 (ja) 2002-10-15
HU9301431D0 (en) 1993-12-28
HUT64768A (en) 1994-02-28
ATE144522T1 (de) 1996-11-15

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