HK81497A - Heterocyclic sulphonamide leukotriene antagonist - Google Patents

Heterocyclic sulphonamide leukotriene antagonist Download PDF

Info

Publication number
HK81497A
HK81497A HK81497A HK81497A HK81497A HK 81497 A HK81497 A HK 81497A HK 81497 A HK81497 A HK 81497A HK 81497 A HK81497 A HK 81497A HK 81497 A HK81497 A HK 81497A
Authority
HK
Hong Kong
Prior art keywords
leukotriene antagonist
sulphonamide
heterocyclic
heterocyclic sulphonamide
peaks
Prior art date
Application number
HK81497A
Other languages
English (en)
Inventor
Paul Edwards Martin
David Sherwood John
Original Assignee
Astrazeneca Uk Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Uk Limited filed Critical Astrazeneca Uk Limited
Publication of HK81497A publication Critical patent/HK81497A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK81497A 1990-12-12 1997-06-19 Heterocyclic sulphonamide leukotriene antagonist HK81497A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909027018A GB9027018D0 (en) 1990-12-12 1990-12-12 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
HK81497A true HK81497A (en) 1997-06-27

Family

ID=10686919

Family Applications (1)

Application Number Title Priority Date Filing Date
HK81497A HK81497A (en) 1990-12-12 1997-06-19 Heterocyclic sulphonamide leukotriene antagonist

Country Status (28)

Country Link
US (1) US5294636A (enExample)
EP (1) EP0490649B1 (enExample)
JP (1) JP2650807B2 (enExample)
KR (1) KR100194479B1 (enExample)
CN (2) CN1032469C (enExample)
AP (1) AP286A (enExample)
AT (1) ATE145199T1 (enExample)
AU (1) AU656344B2 (enExample)
CA (1) CA2056067C (enExample)
CZ (1) CZ288151B6 (enExample)
DE (1) DE69123123T2 (enExample)
DK (1) DK0490649T3 (enExample)
ES (1) ES2094797T3 (enExample)
FI (1) FI101296B1 (enExample)
GB (2) GB9027018D0 (enExample)
GR (1) GR3021605T3 (enExample)
HK (1) HK81497A (enExample)
HU (2) HU213109B (enExample)
IE (1) IE914316A1 (enExample)
IL (1) IL100090A (enExample)
MX (1) MX9102475A (enExample)
MY (1) MY108629A (enExample)
NZ (1) NZ240940A (enExample)
PH (1) PH30041A (enExample)
RU (1) RU2107682C1 (enExample)
SK (1) SK279018B6 (enExample)
TW (1) TW222264B (enExample)
ZA (1) ZA919772B (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0455596B1 (de) * 1990-05-04 1994-11-02 Novartis AG Substituierte Indole
IL100091A (en) * 1990-12-12 1998-08-16 Zeneca Ltd Pharmaceutical compositions containing a physical form of n-[4-[5-(cyclopentyloxycarbonyl)amino-1-methyl indol-3-yl-methyl]-2-methylbenzenesulpho-namide and process for their preparation
GB9119001D0 (en) * 1991-09-05 1991-10-23 Ici Plc Pharmaceutical agents
GR1001368B (el) * 1992-10-08 1993-10-29 Ici Plc Φαρμακευτικοί φορείς.
DE4235133A1 (de) * 1992-10-19 1994-04-21 Bayer Ag Kristallines (R)-(-)-2-Cycloheptyl-N-methylsulfonyl-[4-(2-chinolinyl-methoxy)-phenyl]-acetamid
IL111080A (en) * 1993-10-01 1999-08-17 Astra Ab Method for treating a finely divided powder medicament
IS1736B (is) 1993-10-01 1999-12-30 Astra Ab Aðferð og tæki sem stuðla að aukinni samloðun agna
GB9723985D0 (en) * 1997-11-14 1998-01-14 Zeneca Ltd Pharmaceutical compositions
GB9726735D0 (en) * 1997-12-18 1998-02-18 Zeneca Ltd Pharmaceutical compositions
GB9900339D0 (en) * 1999-01-09 1999-02-24 Zeneca Ltd Chemical compounds
GB0003305D0 (en) * 2000-02-15 2000-04-05 Zeneca Ltd Pyrimidine derivatives
IL139243A0 (en) * 2000-10-24 2001-11-25 Internat Specialty Products Is Ethanolate of zafirlukast, process for manufacture and pharmaceutical compositions thereof
TWI353979B (en) * 2002-04-10 2011-12-11 Nippon Zoki Pharmaceutical Co Novel crystal form of 5-hydroxy-1-methylhydantoin
US20090317476A1 (en) * 2003-07-31 2009-12-24 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20050026882A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20050113410A1 (en) * 2003-11-03 2005-05-26 Mark Tawa Pharmaceutical salts of zafirlukast
US20080254114A1 (en) * 2005-03-03 2008-10-16 Elan Corporation Plc Controlled Release Compositions Comprising Heterocyclic Amide Derivative Nanoparticles
US20070197467A1 (en) * 2006-02-06 2007-08-23 Srinivasulu Rangineni Zafirlukast compositions
US20090012146A1 (en) * 2007-07-02 2009-01-08 Giridhar Reddy Buggana Solubility-enhanced pharmaceutical compositions comprising zafirlukast
CA2695008A1 (en) * 2007-07-30 2009-02-05 Auspex Pharmaceuticals, Inc. Substituted indoles
TWI469965B (zh) * 2008-12-22 2015-01-21 Ono Pharmaceutical Co 乙炔基吲哚化合物
WO2014012954A1 (en) 2012-07-18 2014-01-23 Takeda Gmbh Treatment of partly controlled or uncontrolled severe asthma
CN103396353B (zh) * 2013-08-23 2015-05-20 海南通用三洋药业有限公司 一种扎鲁司特无定型态及其制备方法
JP2017503814A (ja) 2014-01-22 2017-02-02 タケダ ゲー・エム・ベー・ハーＴａｋｅｄａ ＧｍｂＨ 部分的コントロール状態の重症喘息またはコントロール不良状態の重症喘息のｐｄｅ４インヒビターを用いた（およびロイコトリエン調節薬と組み合わせて用いた）治療
PT109030B (pt) * 2015-12-15 2019-09-25 Hovione Farmaciência, S.A. Preparação de partículas inaláveis de zafirlucaste
CA3052071A1 (en) 2017-01-30 2018-08-02 Western New England University Thiol isomerases inhibitors and use thereof
WO2022243942A1 (en) 2021-05-19 2022-11-24 Quercis Pharma AG Quercetin-containing compositions for use in treating amyotrophic lateral sclerosis
WO2023214391A1 (en) 2022-05-06 2023-11-09 Quercis Pharma AG Method for treating cancers and neurological diseases using quercetin-containing compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4161516A (en) * 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
GB8607294D0 (en) * 1985-04-17 1986-04-30 Ici America Inc Heterocyclic amide derivatives

Also Published As

Publication number Publication date
JPH04266872A (ja) 1992-09-22
HUT60717A (en) 1992-10-28
DK0490649T3 (da) 1997-04-21
ES2094797T3 (es) 1997-02-01
US5294636A (en) 1994-03-15
HU211125A9 (en) 1995-10-30
CN1063100A (zh) 1992-07-29
TW222264B (enExample) 1994-04-11
GR3021605T3 (en) 1997-02-28
GB9027018D0 (en) 1991-01-30
CS375891A3 (en) 1992-06-17
SK279018B6 (sk) 1998-05-06
AP9100341A0 (en) 1992-01-31
AU656344B2 (en) 1995-02-02
HU213109B (en) 1997-02-28
ZA919772B (en) 1992-09-30
IL100090A (en) 1996-09-12
CN1032469C (zh) 1996-08-07
GB9126353D0 (en) 1992-02-12
FI101296B (fi) 1998-05-29
MX9102475A (es) 1992-06-01
ATE145199T1 (de) 1996-11-15
KR920012031A (ko) 1992-07-25
CZ288151B6 (en) 2001-05-16
MY108629A (en) 1996-10-31
KR100194479B1 (ko) 1999-06-15
CN1074411C (zh) 2001-11-07
AP286A (en) 1993-09-26
IE914316A1 (en) 1992-06-17
RU2107682C1 (ru) 1998-03-27
CN1148491A (zh) 1997-04-30
GB2250743B (en) 1995-02-15
CA2056067C (en) 2001-09-04
DE69123123D1 (de) 1996-12-19
AU8899591A (en) 1992-06-18
GB2250743A (en) 1992-06-17
FI915825A0 (fi) 1991-12-11
FI915825L (fi) 1992-06-13
JP2650807B2 (ja) 1997-09-10
IL100090A0 (en) 1992-08-18
HU913863D0 (en) 1992-02-28
NZ240940A (en) 1994-05-26
EP0490649B1 (en) 1996-11-13
EP0490649A1 (en) 1992-06-17
DE69123123T2 (de) 1997-03-06
CA2056067A1 (en) 1992-06-13
FI101296B1 (fi) 1998-05-29
PH30041A (en) 1996-11-08

Similar Documents

Publication Publication Date Title
HK81497A (en) Heterocyclic sulphonamide leukotriene antagonist
WO2001083459A3 (en) Uracil substituted phenyl sulfamoyl carboxamides
AU584124B2 (en) Diarylacetylenes, their preparation and their use
CA2208839A1 (en) Quinuclidine derivatives and medicinal composition thereof
CA2219819A1 (en) Novel compounds, the preparation and use thereof
CA2059708A1 (en) Indole derivatives
AU644008B2 (en) Beta-lactam compounds, and their production and use
EP0386675A3 (en) Xanthine derivatives
BG105384A (en) CRYSTALLINE FORMS OF Et02C-CH2-(R)Cgl-Aze-Pab-OH
CA2017376A1 (en) Diarylstyrylquinoline diacids
AU8474891A (en) 1,3-benzoxazine derivatives, their production and use
CA2087274A1 (en) 4-alkylimidazole derivatives
TW343223B (en) Alumina-coated inorganic titanium dioxide pigment and process for preparing same
CA2227386A1 (en) Piperazine derivatives and their use as 5-ht1a antagonists
NO954488D0 (no) Manganholdig nikkel(II)hydroksyd-pulver, fremgangsmåte for fremstilling derav samt anvendelse av pulveret
USD263878S (en) Root canal screw
AU587995B2 (en) 1-substituted tetralin derivatives, their preparation and their use
CA2269217A1 (en) New 1,7,7-trimethyl-bicyclo[2.2.1]heptane derivatives
JPS5339590A (en) Cam grinder
CA2168193A1 (en) Aryalkyl-thiadiazinones
GB2315413B (en) Herbicidal compositions based on N-isopropyl-N-(4-fluorophenyl)(5-trifluoromethyl-1,3,4-thiadiazol-2-yloxy)acetamide
IE800449L (en) Pyrazoline derivatives.
FI933719L (fi) 4-((2-bensotiazolyl)metylamino)-a-((3,4-difluorfenoxi)metyl)-1-piperidinetanol
CA2309474A1 (en) New 4-arylpiperidine derivatives for the treatment of pruritus
CA2051894A1 (en) Substituted 5-Alkoxy-1,2,4-Triazol-3-(Thi)Ones

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20051211