HK61486A - 4-aroylimidazol-2-ones - Google Patents

4-aroylimidazol-2-ones

Info

Publication number
HK61486A
HK61486A HK614/86A HK61486A HK61486A HK 61486 A HK61486 A HK 61486A HK 614/86 A HK614/86 A HK 614/86A HK 61486 A HK61486 A HK 61486A HK 61486 A HK61486 A HK 61486A
Authority
HK
Hong Kong
Prior art keywords
alkyl
phenyl
hydrogen
alkoxy
hydroxy
Prior art date
Application number
HK614/86A
Other languages
English (en)
Inventor
C. Dage Richard
Martin Grisar J.
A. Schnettler Richard
Original Assignee
Richardson-Merrell Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK61486(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Richardson-Merrell Inc. filed Critical Richardson-Merrell Inc.
Publication of HK61486A publication Critical patent/HK61486A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK614/86A 1979-06-18 1986-08-21 4-aroylimidazol-2-ones HK61486A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4980879A 1979-06-18 1979-06-18
US11920780A 1980-02-07 1980-02-07

Publications (1)

Publication Number Publication Date
HK61486A true HK61486A (en) 1986-08-29

Family

ID=26727558

Family Applications (1)

Application Number Title Priority Date Filing Date
HK614/86A HK61486A (en) 1979-06-18 1986-08-21 4-aroylimidazol-2-ones

Country Status (20)

Country Link
AT (1) AT375349B (en:Method)
AU (1) AU532783B2 (en:Method)
CA (1) CA1132554A (en:Method)
CH (1) CH646155A5 (en:Method)
DE (1) DE3021792A1 (en:Method)
DK (1) DK160269C (en:Method)
ES (1) ES8105299A1 (en:Method)
FR (1) FR2459233A1 (en:Method)
GB (1) GB2055364B (en:Method)
HK (1) HK61486A (en:Method)
HU (1) HU186736B (en:Method)
IE (1) IE50646B1 (en:Method)
IL (1) IL60243A (en:Method)
IT (1) IT1143922B (en:Method)
MY (1) MY8600709A (en:Method)
NL (2) NL193752C (en:Method)
NO (1) NO152841C (en:Method)
NZ (1) NZ193935A (en:Method)
PH (1) PH18683A (en:Method)
SE (2) SE447107B (en:Method)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4526981A (en) * 1981-05-04 1985-07-02 Merrell Dow Pharmaceuticals Inc. [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
JPS57185266A (en) * 1981-05-04 1982-11-15 Merrell Dow Pharma 4-oxymethyl-5-acyl-1,3-dihydro-2h-imidazole- 2-one
US4329470A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4381393A (en) * 1981-05-04 1983-04-26 Merrell Dow Pharmaceuticals Inc. 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4371737A (en) * 1981-05-04 1983-02-01 Merrell Dow Pharmaceuticals Inc. 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4329471A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US4367236A (en) * 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2007530563A (ja) * 2004-03-22 2007-11-01 ミオゲン インコーポレイティッド （ｓ）−エノキシモンスルホキシドおよびｐｄｅ−ｉｉｉ媒介疾患の治療におけるその使用
WO2005092333A1 (en) * 2004-03-22 2005-10-06 Myogen, Inc. (r)-enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
CN101355876B (zh) 2005-11-09 2012-09-05 康宾纳特克斯公司 一种适用于眼部给药的组合物
CN103601792B (zh) 2007-06-04 2016-06-29 协同医药品公司 有效用于胃肠功能紊乱、炎症、癌症和其他疾病治疗的鸟苷酸环化酶激动剂
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (en) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (zh) 2011-03-01 2018-10-19 辛纳吉制药公司 制备鸟苷酸环化酶c激动剂的方法
EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
HK1218629A1 (zh) 2013-02-25 2017-03-03 Bausch Health Ireland Limited 用於结肠清洁的鸟苷酸环化酶受体激动剂
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
SI3004138T1 (sl) 2013-06-05 2024-07-31 Bausch Health Ireland Limited Ultra čisti agonisti gvanilat ciklaze C, postopek za njihovo pripravo in uporabo
MX375926B (es) 2013-08-09 2025-03-07 Ardelyx Inc Compuestos y metodos para inhibir el transporte de fosfato.
EP3972599A1 (en) 2019-05-21 2022-03-30 Ardelyx, Inc. Combination for lowering serum phosphate in a patient
CN114539157B (zh) * 2022-03-03 2023-12-22 曲靖师范学院 一种碘促进氧化法制备4-碘代n-芳基吡唑类化合物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them

Also Published As

Publication number Publication date
GB2055364B (en) 1983-06-08
MY8600709A (en) 1986-12-31
IT1143922B (it) 1986-10-29
CA1132554A (en) 1982-09-28
NO801796L (no) 1980-12-19
IE801162L (en) 1980-12-18
SE8501452D0 (sv) 1985-03-25
SE464559B (sv) 1991-05-13
PH18683A (en) 1985-08-29
NO152841B (no) 1985-08-19
NL8003498A (nl) 1980-12-22
NL193752C (nl) 2000-09-04
IE50646B1 (en) 1986-06-11
NZ193935A (en) 1985-05-31
CH646155A5 (de) 1984-11-15
ATA314280A (de) 1983-12-15
IT8048997A0 (it) 1980-06-17
SE447107B (sv) 1986-10-27
ES492255A0 (es) 1981-06-01
GB2055364A (en) 1981-03-04
SE8004253L (sv) 1980-12-19
AU5911880A (en) 1981-01-08
HU186736B (en) 1985-09-30
SE8501452L (sv) 1985-03-25
NO152841C (no) 1985-11-27
FR2459233A1 (fr) 1981-01-09
AU532783B2 (en) 1983-10-13
AT375349B (de) 1984-07-25
FR2459233B1 (en:Method) 1983-09-23
DK259080A (da) 1980-12-19
DE3021792C2 (en:Method) 1989-08-10
DK160269C (da) 1991-07-22
DK160269B (da) 1991-02-18
NL193752B (nl) 2000-05-01
IL60243A (en) 1987-01-30
DE3021792A1 (de) 1981-01-22
NL300015I1 (nl) 2000-11-01
IL60243A0 (en) 1980-09-16
NL300015I2 (nl) 2000-10-02
ES8105299A1 (es) 1981-06-01

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Legal Events

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PE Patent expired