HK39780A - Process for the preparation of cephadroxil - Google Patents

Process for the preparation of cephadroxil

Info

Publication number
HK39780A
HK39780A HK397/80A HK39780A HK39780A HK 39780 A HK39780 A HK 39780A HK 397/80 A HK397/80 A HK 397/80A HK 39780 A HK39780 A HK 39780A HK 39780 A HK39780 A HK 39780A
Authority
HK
Hong Kong
Prior art keywords
cephadroxil
preparation
Prior art date
Application number
HK397/80A
Other languages
English (en)
Inventor
J Stemer
D Bouzard
A Weber
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10087928&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK39780(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of HK39780A publication Critical patent/HK39780A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK397/80A 1976-04-27 1980-07-31 Process for the preparation of cephadroxil HK39780A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB17028/76A GB1532682A (en) 1976-04-27 1976-04-27 Process for the preparation of cephadroxil

Publications (1)

Publication Number Publication Date
HK39780A true HK39780A (en) 1980-08-08

Family

ID=10087928

Family Applications (1)

Application Number Title Priority Date Filing Date
HK397/80A HK39780A (en) 1976-04-27 1980-07-31 Process for the preparation of cephadroxil

Country Status (26)

Country Link
US (3) US4234721A (fr)
JP (2) JPS6022717B2 (fr)
AT (1) AT350183B (fr)
AU (1) AU510338B2 (fr)
BE (1) BE853974A (fr)
CA (1) CA1115268A (fr)
CH (1) CH632270A5 (fr)
CY (1) CY1066A (fr)
DE (1) DE2718741C2 (fr)
DK (1) DK157026C (fr)
ES (1) ES458241A1 (fr)
FI (1) FI67704C (fr)
FR (2) FR2349589A1 (fr)
GB (1) GB1532682A (fr)
GR (1) GR72788B (fr)
HK (1) HK39780A (fr)
IE (1) IE44872B1 (fr)
IT (1) IT8049917A0 (fr)
KE (1) KE3064A (fr)
LU (1) LU77202A1 (fr)
MY (1) MY8100135A (fr)
NL (1) NL7704618A (fr)
PH (2) PH16581A (fr)
SE (1) SE437521B (fr)
YU (2) YU39801B (fr)
ZA (1) ZA772485B (fr)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR820001564B1 (ko) * 1981-05-09 1982-09-02 동신제약 주식회사 새로운 실릴화제를 이용한 세팔로스포린 유도체의 제조방법
FR2555989B1 (fr) * 1983-12-06 1987-02-20 Bristol Myers Sa Monohydrate de chlorocephadroxyle
JPS60169486A (ja) * 1984-02-10 1985-09-02 Yamanouchi Pharmaceut Co Ltd 7−アミノ−3−置換メチル−3−セフエム−4−カルボン酸およびその低級アルキルシリル誘導体の製造法
GB8714180D0 (en) * 1987-06-17 1987-07-22 Rifar Srl Anhydrous crystalline cefadroxil
US4962195A (en) * 1987-04-24 1990-10-09 Rifar S.R.L. Solvate of cefadroxyl
US4904776A (en) * 1987-04-24 1990-02-27 Rifar S.R.L. Method for producing crystalline cefadroxil hemihydrate
US5023331A (en) * 1987-04-24 1991-06-11 Rifar S.R.L. Cefadroxil solvates
US4898938A (en) * 1987-08-03 1990-02-06 Rifar S.R.L. Method for preparing crystalline cefadroxil monohydrate
IT1233863B (it) * 1988-02-24 1992-04-21 Opos Biochimica Srl Procedimento per la preparazione dell'acido 7-(d(-)-alfa-amino-alfa- (p-idrossifenil)acetamido)-3-metil-3-cefem-4-carbossilico monoidrato
US5034522A (en) * 1988-08-02 1991-07-23 Biocraft Laboratories, Inc. Method for the production of 3-methyl cephem derivatives
ES2063974T3 (es) * 1989-07-10 1995-01-16 Chemferm Vof Una nueva forma estable de cefradina, un proceso para su produccion y compuestos intermedios usados en tal proceso.
US5142043A (en) * 1990-05-10 1992-08-25 Biocraft Laboratories, Inc. Process for preparing cephalexin monohydrate
US6248881B1 (en) 1991-03-08 2001-06-19 Biochemie Gmbh Intermediates and process for the production of 3-vinyl cephalosporins
AT396106B (de) * 1991-03-08 1993-06-25 Biochemie Gmbh Neues verfahren zur herstellung von 3-vinylcephalosporinverbindungen
DE69231815T2 (de) 1991-03-08 2001-09-27 Biochemie Gmbh Verfahren zur Herstellung von Cephalosporinen und Zwischenprodukte in diesem Verfahren
AU694419B2 (en) * 1993-03-12 1998-07-23 Zoetis P&U Llc Crystalline ceftiofur free acid
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
PT755393E (pt) 1994-04-15 2002-04-29 Upjohn Co Novas formas cristalinas de 1-¬5-metanossulfonamidoimdolil-2-carbonil|-4-¬3-(1-metiletilamino)-2-piridinil|piperazina
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
US5574154A (en) * 1994-09-29 1996-11-12 Alnejma Bulk Pharmaceutical Co. A.B.P.C. Process for the preparation of cephalosporanic compounds
GB9423459D0 (en) * 1994-11-21 1995-01-11 Biochemie Gmbh Silylation process
IT1289955B1 (it) * 1997-02-21 1998-10-19 Solchem Italiana Spa Acyclovir sale sodico biidrato e sua preparazione
US6080427A (en) * 1997-04-17 2000-06-27 Bristol-Myers Squibb Company Cefadroxil monohydrate tablet formulation
IN190389B (fr) 1999-07-14 2003-07-26 Ranbaxy Lab Ltd
AU5418300A (en) * 1999-07-14 2001-01-30 Ranbaxy Laboratories Limited Process for preparing crystalline cefadroxil hemihydrate from cefadroxil dimethylformamide solvate
US6569887B2 (en) * 2001-08-24 2003-05-27 Dov Pharmaceuticals Inc. (−)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake
US20060173064A1 (en) * 2001-08-24 2006-08-03 Lippa Arnold S (-)-1-(3,4-Dichlorophenyl)-3-azabi cyclo[3.1.0]hexane, compositions thereof, and uses for treating alcohol-related disorders
US7235655B2 (en) * 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
US20080081834A1 (en) 2002-07-31 2008-04-03 Lippa Arnold S Methods and compositions employing bicifadine for treating disability or functional impairment associated with acute pain, chronic pain, or neuropathic disorders
US20040077849A1 (en) * 2002-10-16 2004-04-22 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefadroxil
JP2006519162A (ja) * 2002-11-08 2006-08-24 ディオーブイ ファーマシューティカル,インク. ビシファジン塩酸塩の多形
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
US7230097B2 (en) 2003-03-10 2007-06-12 Lupin Ltd. Process for preparation of 7-[α-Amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid
US20070072945A1 (en) * 2004-03-31 2007-03-29 Pohoreski Anton Sulphur-containing oils for controlling plant pathogens and stimulating nutrient uptake
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
US20060100263A1 (en) * 2004-11-05 2006-05-11 Anthony Basile Antipyretic compositions and methods
CA2659215C (fr) 2005-07-27 2018-07-10 Dov Pharmaceutical, Inc. Nouveaux 1-aryl-3-azabicyclo[3.1.0]hexanes : synthese et emploi dans le traitement des troubles neuropsychiatriques
US20080045725A1 (en) * 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
CN101448842A (zh) * 2006-05-19 2009-06-03 帝斯曼知识产权资产管理有限公司 一种用于结晶头孢羟氨苄的方法
US8138377B2 (en) * 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US20080269348A1 (en) * 2006-11-07 2008-10-30 Phil Skolnick Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use
PL2118074T3 (pl) 2007-02-01 2014-06-30 Resverlogix Corp Związki chemiczne do celów profilaktyki i leczenia chorób układu sercowo-naczyniowego
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
US20090069374A1 (en) * 2007-06-06 2009-03-12 Phil Skolnick Novel 1-Heteroaryl-3-Azabicyclo[3.1.0]Hexanes, Methods For Their Preparation And Their Use As Medicaments
US9238640B2 (en) 2009-03-18 2016-01-19 Resverlogix Corp. Anti-inflammatory agents
CN102408438B (zh) * 2010-09-26 2015-01-07 石药集团中奇制药技术(石家庄)有限公司 一种头孢丙烯一水合物的制备方法
CN102134250B (zh) * 2011-01-19 2013-03-13 天津大学 一种头孢羟氨苄单水合物的结晶方法及结晶

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US29164A (en) * 1860-07-17 Improvement in fish-oils
US3489752A (en) * 1967-09-05 1970-01-13 Bristol Myers Co 7-amino-cephalosporanic and decephalosporanic acid derivatives
USRE29164E (en) 1967-09-05 1977-03-29 Bristol-Myers Company 7-Amino-cephalosporanic and decephalosporanic acid derivatives
US3655656A (en) * 1970-06-04 1972-04-11 Lilly Co Eli Crystalline cephalexin monohydrate
US3694437A (en) * 1970-08-19 1972-09-26 Lilly Co Eli Process for preparing cephalosporin compounds
US3781282A (en) * 1971-01-20 1973-12-25 W Garbrecht Cephalosporin process and product
JPS5318515B2 (fr) 1971-12-17 1978-06-15
DE2163514A1 (de) * 1971-12-21 1973-07-05 Toyama Chemical Co Ltd Verfahren zur herstellung von cephalosporinen
FR2166316A1 (en) * 1972-01-07 1973-08-17 Toyama Chemical Co Ltd 7-acylcephalosporins - prepd via a silylated inter
US3985741A (en) * 1972-09-15 1976-10-12 Bristol-Myers Company Production of p-hydroxycephalexin
DE2354427A1 (de) 1972-11-02 1974-05-16 Lorenzini Sas Inst Biochim Verfahren zur herstellung von 7-(dalpha-aminophenylacetamido)-3-desacetoxycephalosporansaeure
GB1472746A (en) * 1973-07-05 1977-05-04 Glaxo Lab Ltd Cephalosporin compounds
US4091215A (en) * 1974-06-05 1978-05-23 Bristol-Myers Company 7-D-α-Amino-.alpha.-(p-acetoxyphenyl)acetamido-3-methyl-3-cephem-4-carboxylic acid
GB1476981A (en) 1974-06-05 1977-06-16 Bristol Myers Co Substituted penicillanic acids
AU2550077A (en) * 1976-06-14 1978-11-30 Merck Patent Gmbh Penicillins and cephalosporins
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
NL162387C (nl) * 1977-09-06 1980-05-16 Gist Brocades Nv Werkwijze voor het bereiden van 6-(d-alpha-amino-p- -hydroxyfenylacetamido)penicillanzuur.
IT1126544B (it) * 1979-12-07 1986-05-21 Dobfar Spa Procedimento per la preparazione di derivati dell'acido 7-amino-desacetossi cefalosporanico

Also Published As

Publication number Publication date
CH632270A5 (de) 1982-09-30
BE853974A (fr) 1977-10-26
US4234721A (en) 1980-11-18
SE7704739L (sv) 1977-12-01
YU39801B (en) 1985-04-30
AU2460777A (en) 1978-11-02
JPS52142091A (en) 1977-11-26
DE2718741C2 (de) 1985-03-21
LU77202A1 (fr) 1977-11-22
DK183277A (da) 1977-10-28
YU137982A (en) 1983-04-30
AT350183B (de) 1979-05-10
ATA296277A (de) 1978-10-15
CA1115268A (fr) 1981-12-29
AU510338B2 (en) 1980-06-19
JPH0246009B2 (fr) 1990-10-12
ZA772485B (en) 1978-03-29
PH17254A (en) 1984-07-03
IT8049917A0 (it) 1980-10-16
FR2365570B1 (fr) 1980-06-06
SE437521B (sv) 1985-03-04
YU43081B (en) 1989-02-28
KE3064A (en) 1980-07-25
FR2349589A1 (fr) 1977-11-25
GB1532682A (en) 1978-11-22
NL7704618A (nl) 1977-10-31
GR72788B (fr) 1983-12-05
FR2349589B1 (fr) 1981-11-20
IE44872L (en) 1977-10-27
US4504657A (en) 1985-03-12
USRE31730E (en) 1984-11-13
CY1066A (en) 1980-10-24
MY8100135A (en) 1981-12-31
FR2365570A1 (fr) 1978-04-21
DE2718741A1 (de) 1977-11-17
FI67704B (fi) 1985-01-31
JPS60185718A (ja) 1985-09-21
DK157026C (da) 1990-04-02
ES458241A1 (es) 1978-11-01
IE44872B1 (en) 1982-04-21
YU108677A (en) 1982-10-31
JPS6022717B2 (ja) 1985-06-03
PH16581A (en) 1983-11-22
FI771339A (fr) 1977-10-28
DK157026B (da) 1989-10-30
FI67704C (fi) 1985-05-10

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Legal Events

Date Code Title Description
NR Patent deemed never to have been added to the register under section 13(7) of patents (transitional arrangements) rules