FI67704B - Foerfarande foer framstaellning av ett nytt terapeutiskt anvaendbart kristallint monohydrat av 7-(d-alfa-amino-alfa-(p-hydroxifenyl)acetamido)-3-metyl-3-cefem-4-karboxylsyra - Google Patents

Foerfarande foer framstaellning av ett nytt terapeutiskt anvaendbart kristallint monohydrat av 7-(d-alfa-amino-alfa-(p-hydroxifenyl)acetamido)-3-metyl-3-cefem-4-karboxylsyra

Info

Publication number
FI67704B
FI67704B FI771339A FI771339A FI67704B FI 67704 B FI67704 B FI 67704B FI 771339 A FI771339 A FI 771339A FI 771339 A FI771339 A FI 771339A FI 67704 B FI67704 B FI 67704B
Authority
FI
Finland
Prior art keywords
alpha
syrase
framstating
anvaendbart
cefem
Prior art date
Application number
FI771339A
Other languages
English (en)
Other versions
FI771339A (fi
FI67704C (fi
Inventor
Daniel Bouzard
Abraham Weber
Jaques Stemer
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10087928&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI67704(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI771339A publication Critical patent/FI771339A/fi
Publication of FI67704B publication Critical patent/FI67704B/fi
Application granted granted Critical
Publication of FI67704C publication Critical patent/FI67704C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI771339A 1976-04-27 1977-04-27 Foerfarande foer framstaellning av ett nytt terapeutiskt anvaendbart kristallint monohydrat av 7-(d-alfa-amino-alfa-(p-hydroxifenyl)acetamido)-3-metyl-3-cefem-4-karboxylsyra FI67704C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB17028/76A GB1532682A (en) 1976-04-27 1976-04-27 Process for the preparation of cephadroxil
GB1702876 1976-04-27

Publications (3)

Publication Number Publication Date
FI771339A FI771339A (fi) 1977-10-28
FI67704B true FI67704B (fi) 1985-01-31
FI67704C FI67704C (fi) 1985-05-10

Family

ID=10087928

Family Applications (1)

Application Number Title Priority Date Filing Date
FI771339A FI67704C (fi) 1976-04-27 1977-04-27 Foerfarande foer framstaellning av ett nytt terapeutiskt anvaendbart kristallint monohydrat av 7-(d-alfa-amino-alfa-(p-hydroxifenyl)acetamido)-3-metyl-3-cefem-4-karboxylsyra

Country Status (26)

Country Link
US (3) US4234721A (fi)
JP (2) JPS6022717B2 (fi)
AT (1) AT350183B (fi)
AU (1) AU510338B2 (fi)
BE (1) BE853974A (fi)
CA (1) CA1115268A (fi)
CH (1) CH632270A5 (fi)
CY (1) CY1066A (fi)
DE (1) DE2718741C2 (fi)
DK (1) DK157026C (fi)
ES (1) ES458241A1 (fi)
FI (1) FI67704C (fi)
FR (2) FR2349589A1 (fi)
GB (1) GB1532682A (fi)
GR (1) GR72788B (fi)
HK (1) HK39780A (fi)
IE (1) IE44872B1 (fi)
IT (1) IT8049917A0 (fi)
KE (1) KE3064A (fi)
LU (1) LU77202A1 (fi)
MY (1) MY8100135A (fi)
NL (1) NL7704618A (fi)
PH (2) PH16581A (fi)
SE (1) SE437521B (fi)
YU (2) YU39801B (fi)
ZA (1) ZA772485B (fi)

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US4962195A (en) * 1987-04-24 1990-10-09 Rifar S.R.L. Solvate of cefadroxyl
US5023331A (en) * 1987-04-24 1991-06-11 Rifar S.R.L. Cefadroxil solvates
US4898938A (en) * 1987-08-03 1990-02-06 Rifar S.R.L. Method for preparing crystalline cefadroxil monohydrate
IT1233863B (it) * 1988-02-24 1992-04-21 Opos Biochimica Srl Procedimento per la preparazione dell'acido 7-(d(-)-alfa-amino-alfa- (p-idrossifenil)acetamido)-3-metil-3-cefem-4-carbossilico monoidrato
US5034522A (en) * 1988-08-02 1991-07-23 Biocraft Laboratories, Inc. Method for the production of 3-methyl cephem derivatives
WO1991000865A1 (en) * 1989-07-10 1991-01-24 Gema S.A. A novel stable form of cephradine, process for its production and intermediates used therein
US5142043A (en) * 1990-05-10 1992-08-25 Biocraft Laboratories, Inc. Process for preparing cephalexin monohydrate
US6248881B1 (en) 1991-03-08 2001-06-19 Biochemie Gmbh Intermediates and process for the production of 3-vinyl cephalosporins
DE69231815T2 (de) 1991-03-08 2001-09-27 Biochemie Ges.M.B.H., Kundl Verfahren zur Herstellung von Cephalosporinen und Zwischenprodukte in diesem Verfahren
AT396106B (de) * 1991-03-08 1993-06-25 Biochemie Gmbh Neues verfahren zur herstellung von 3-vinylcephalosporinverbindungen
SK283674B6 (sk) * 1993-03-12 2003-11-04 Pharmacia & Upjohn Company Kryštalická voľná kyselina ceftiofuru a spôsob jej prípravy a farmaceutická kompozícia, ktorá ju obsahuje
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
DE69523447T2 (de) 1994-04-15 2002-05-16 Pharmacia & Upjohn Co., Kalamazoo Kristallformen von 1-[5-methansulfonamidoindolyl-2-carbonyl]-4-[3-[1-methylethylamino]-2-pyridinyl] piperazin
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
US5574154A (en) * 1994-09-29 1996-11-12 Alnejma Bulk Pharmaceutical Co. A.B.P.C. Process for the preparation of cephalosporanic compounds
GB9423459D0 (en) * 1994-11-21 1995-01-11 Biochemie Gmbh Silylation process
IT1289955B1 (it) * 1997-02-21 1998-10-19 Solchem Italiana Spa Acyclovir sale sodico biidrato e sua preparazione
US6080427A (en) * 1997-04-17 2000-06-27 Bristol-Myers Squibb Company Cefadroxil monohydrate tablet formulation
IN190389B (fi) 1999-07-14 2003-07-26 Ranbaxy Lab Ltd
AU5418300A (en) * 1999-07-14 2001-01-30 Ranbaxy Laboratories Limited Process for preparing crystalline cefadroxil hemihydrate from cefadroxil dimethylformamide solvate
US20060173064A1 (en) * 2001-08-24 2006-08-03 Lippa Arnold S (-)-1-(3,4-Dichlorophenyl)-3-azabi cyclo[3.1.0]hexane, compositions thereof, and uses for treating alcohol-related disorders
US6569887B2 (en) * 2001-08-24 2003-05-27 Dov Pharmaceuticals Inc. (−)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake
US7235655B2 (en) * 2002-03-22 2007-06-26 Pharmacia & Upjohn Company Processes to prepare eplerenone
US20080081834A1 (en) 2002-07-31 2008-04-03 Lippa Arnold S Methods and compositions employing bicifadine for treating disability or functional impairment associated with acute pain, chronic pain, or neuropathic disorders
US20040077849A1 (en) * 2002-10-16 2004-04-22 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefadroxil
RU2005117630A (ru) * 2002-11-08 2006-01-20 Дов Фармасьютикал, Инк. (Us) Полиморфы гидрохлорида бицифадина
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
US7230097B2 (en) 2003-03-10 2007-06-12 Lupin Ltd. Process for preparation of 7-[α-Amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid
US20070072945A1 (en) * 2004-03-31 2007-03-29 Pohoreski Anton Sulphur-containing oils for controlling plant pathogens and stimulating nutrient uptake
US20070043100A1 (en) * 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
US20060100263A1 (en) * 2004-11-05 2006-05-11 Anthony Basile Antipyretic compositions and methods
RU2008107336A (ru) * 2005-07-27 2009-09-10 Дов Фармасьютикал, Инк. (Us) Новые 1-арил-з-азабицикло{3.1.0.} гексаны: получение и применение для лечения психоневрологических расстройств
US20080045725A1 (en) 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
KR101420451B1 (ko) * 2006-05-19 2014-07-16 디에스엠 시노켐 파마슈티칼스 네덜란드 비.브이. 세파드록실의 결정화 방법
US8138377B2 (en) * 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US20080269348A1 (en) * 2006-11-07 2008-10-30 Phil Skolnick Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use
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WO2008153937A2 (en) * 2007-06-06 2008-12-18 Dov Pharmaceutical, Inc. Novel 1- heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
CA2992231C (en) 2009-03-18 2022-03-29 Resverlogix Corp. Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents
CN102408438B (zh) * 2010-09-26 2015-01-07 石药集团中奇制药技术（石家庄）有限公司 一种头孢丙烯一水合物的制备方法
CN102134250B (zh) * 2011-01-19 2013-03-13 天津大学 一种头孢羟氨苄单水合物的结晶方法及结晶
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters

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US3489750A (en) * 1967-09-05 1970-01-13 Bristol Myers Co 7-amino-cephalosporanic and decephalosporanic acid derivatives
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US3781282A (en) * 1971-01-20 1973-12-25 W Garbrecht Cephalosporin process and product
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Also Published As

Publication number Publication date
USRE31730E (en) 1984-11-13
JPS52142091A (en) 1977-11-26
FR2365570B1 (fi) 1980-06-06
YU137982A (en) 1983-04-30
DE2718741C2 (de) 1985-03-21
YU43081B (en) 1989-02-28
IE44872B1 (en) 1982-04-21
IE44872L (en) 1977-10-27
US4504657A (en) 1985-03-12
LU77202A1 (fi) 1977-11-22
GB1532682A (en) 1978-11-22
JPH0246009B2 (fi) 1990-10-12
ZA772485B (en) 1978-03-29
PH16581A (en) 1983-11-22
FR2365570A1 (fr) 1978-04-21
FI771339A (fi) 1977-10-28
US4234721A (en) 1980-11-18
KE3064A (en) 1980-07-25
AU2460777A (en) 1978-11-02
PH17254A (en) 1984-07-03
NL7704618A (nl) 1977-10-31
JPS60185718A (ja) 1985-09-21
AT350183B (de) 1979-05-10
HK39780A (en) 1980-08-08
YU108677A (en) 1982-10-31
DK157026C (da) 1990-04-02
DK183277A (da) 1977-10-28
JPS6022717B2 (ja) 1985-06-03
CA1115268A (en) 1981-12-29
ES458241A1 (es) 1978-11-01
IT8049917A0 (it) 1980-10-16
SE437521B (sv) 1985-03-04
GR72788B (fi) 1983-12-05
FR2349589A1 (fr) 1977-11-25
FI67704C (fi) 1985-05-10
ATA296277A (de) 1978-10-15
MY8100135A (en) 1981-12-31
FR2349589B1 (fi) 1981-11-20
CH632270A5 (de) 1982-09-30
YU39801B (en) 1985-04-30
CY1066A (en) 1980-10-24
DK157026B (da) 1989-10-30
DE2718741A1 (de) 1977-11-17
AU510338B2 (en) 1980-06-19
SE7704739L (sv) 1977-12-01
BE853974A (fr) 1977-10-26

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Owner name: BRISTOL-MYERS CO