HK27088A - 7-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinoline-carboxylic acid,processes for their preparation and antibacterial agents containing them - Google Patents

7-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinoline-carboxylic acid,processes for their preparation and antibacterial agents containing them

Info

Publication number
HK27088A
HK27088A HK270/88A HK27088A HK27088A HK 27088 A HK27088 A HK 27088A HK 270/88 A HK270/88 A HK 270/88A HK 27088 A HK27088 A HK 27088A HK 27088 A HK27088 A HK 27088A
Authority
HK
Hong Kong
Prior art keywords
difluoro
quinoline
cyclopropyl
dihydro
oxo
Prior art date
Application number
HK270/88A
Other languages
English (en)
Inventor
Klaus Dr Grohe
Uwe Dr Petersen
Hans-Joachim Dr Zeiler
Karl Georg Dr Metzger
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6199330&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK27088(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of HK27088A publication Critical patent/HK27088A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Fodder In General (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HK270/88A 1983-05-18 1988-04-14 7-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinoline-carboxylic acid,processes for their preparation and antibacterial agents containing them HK27088A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833318145 DE3318145A1 (de) 1983-05-18 1983-05-18 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel

Publications (1)

Publication Number Publication Date
HK27088A true HK27088A (en) 1988-04-22

Family

ID=6199330

Family Applications (1)

Application Number Title Priority Date Filing Date
HK270/88A HK27088A (en) 1983-05-18 1988-04-14 7-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinoline-carboxylic acid,processes for their preparation and antibacterial agents containing them

Country Status (13)

Country Link
US (2) US4556658A (es)
EP (1) EP0126355B1 (es)
JP (3) JPH0643402B2 (es)
KR (1) KR870000921B1 (es)
AU (1) AU573765B2 (es)
CA (1) CA1304738C (es)
CY (1) CY1487A (es)
DE (2) DE3318145A1 (es)
DK (2) DK164902C (es)
ES (4) ES532380A0 (es)
GR (1) GR79952B (es)
HK (1) HK27088A (es)
PT (1) PT78588B (es)

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US5530158A (en) * 1984-06-04 1996-06-25 Bayer Aktiengesellschaft 2,4,5-trihalogeno- and 2,3,4,5-tetrahalogenobenzene derivatives
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JPH0635457B2 (ja) * 1985-06-28 1994-05-11 杏林製薬株式会社 ピリドンカルボン酸誘導体およびその製造方法
DE3608745A1 (de) * 1985-07-24 1987-01-29 Bayer Ag Bakterizide zubereitungen zur anwendung auf dem gebiet der veterinaermedizin
US4782180A (en) * 1985-09-09 1988-11-01 Warner-Lambert Company Process for tetrafluorobenzoic acid
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DE3617803A1 (de) * 1985-11-07 1987-11-19 Bayer Ag Verwendung von gyrasehemmern zur dekontamination von mycoplasma-infizierten zellkulturen
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
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US4840956A (en) * 1986-02-18 1989-06-20 Warner-Lambert Company Novel disubstituted-7-pyrrolidinoquinoline antibacterial agents
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EP0242789A3 (en) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Novel quinoline derivates and processes for preparation thereof
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US4762845A (en) * 1986-05-21 1988-08-09 Abbott Laboratories 7-(3-Substituted imino-1-pyrrolidinyl)-quinolone-3-carboxylic acids
DE3635218A1 (de) * 1986-10-16 1988-04-21 Bayer Ag 7-amino-1-cyclopropyl-8-chlor-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
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US5290934A (en) * 1987-04-16 1994-03-01 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US5563138A (en) * 1987-04-16 1996-10-08 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
DE3724466A1 (de) * 1987-07-24 1989-02-02 Bayer Ag Verfahren zur herstellung von chinoloncarbonsaeuren
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JPH02138278A (ja) * 1987-10-12 1990-05-28 Yoshitomi Pharmaceut Ind Ltd キノロンカルボン酸化合物
US4889857A (en) * 1987-10-12 1989-12-26 Yoshitomi Pharmaceutical Industries, Ltd. Quinolonecarboxylic acid compounds and pharmaceutical use thereof
US5173484A (en) * 1988-02-05 1992-12-22 Bayer Aktiengesellschaft Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
US5233091A (en) * 1988-06-21 1993-08-03 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
JPH0674261B2 (ja) * 1988-06-21 1994-09-21 塩野義製薬株式会社 キノロンカルボン酸誘導体
US5039682A (en) * 1988-06-21 1991-08-13 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
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DE3918544A1 (de) * 1989-06-07 1990-12-13 Bayer Ag Verfahren zur herstellung von 7-(3-amino- sowie 3-amino-methyl-1-pyrrolidinyl)-3-chinolon- carbonsaeuren sowie -naphthyridoncarbonsaeuren
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JP2644610B2 (ja) * 1990-06-12 1997-08-25 三共株式会社 キノロンカルボン酸誘導体
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IL74244A (en) * 1984-02-17 1988-06-30 Warner Lambert Co Quinoline derivatives,their preparation and pharmaceutical compositions containing them
DE3420116A1 (de) * 1984-05-30 1985-12-05 Bayer Ag, 5090 Leverkusen Immunstimulierende mittel
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Also Published As

Publication number Publication date
GR79952B (es) 1984-10-31
JPH0643402B2 (ja) 1994-06-08
US4556658A (en) 1985-12-03
CA1304738C (en) 1992-07-07
ES8602753A1 (es) 1985-12-01
EP0126355B1 (de) 1987-09-09
CY1487A (en) 1989-12-08
ES8602754A1 (es) 1985-12-01
ES8602755A1 (es) 1985-12-01
ES8507535A1 (es) 1985-09-01
ES540890A0 (es) 1985-12-01
ES540891A0 (es) 1985-12-01
ES540892A0 (es) 1985-12-01
AU3530084A (en) 1986-05-15
DK247084A (da) 1984-11-19
EP0126355A1 (de) 1984-11-28
JPS59212474A (ja) 1984-12-01
DK154591D0 (da) 1991-09-03
JPH0559007A (ja) 1993-03-09
DK154591A (da) 1991-09-03
KR860004048A (ko) 1986-06-16
DK247084D0 (da) 1984-05-17
US4556658B1 (es) 1987-09-15
DK164902C (da) 1993-01-18
DK8402470A (es) 1984-11-19
DK163992B (da) 1992-04-27
JPH0592922A (ja) 1993-04-16
JPH0826001B2 (ja) 1996-03-13
DK163992C (da) 1992-09-21
DK164902B (da) 1992-09-07
KR870000921B1 (ko) 1987-05-07
ES532380A0 (es) 1985-09-01
AU573765B2 (en) 1988-06-23
JPH0764731B2 (ja) 1995-07-12
PT78588B (en) 1986-06-26
DE3465989D1 (en) 1987-10-15
US4952695A (en) 1990-08-28
DE3318145A1 (de) 1984-11-22
PT78588A (en) 1984-06-01

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