HK18696A - Peptides having tachykinin antagonist activity a process for preparation thereof and pharmaceutical compositions comprising the same - Google Patents

Peptides having tachykinin antagonist activity a process for preparation thereof and pharmaceutical compositions comprising the same

Info

Publication number
HK18696A
HK18696A HK18696A HK18696A HK18696A HK 18696 A HK18696 A HK 18696A HK 18696 A HK18696 A HK 18696A HK 18696 A HK18696 A HK 18696A HK 18696 A HK18696 A HK 18696A
Authority
HK
Hong Kong
Prior art keywords
preparation
pharmaceutical compositions
peptides
same
antagonist activity
Prior art date
Application number
HK18696A
Other languages
English (en)
Inventor
Matsuo Masaaki
Hagiwara Daijiro
Miyake Hiroshi
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of HK18696A publication Critical patent/HK18696A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Two-Way Televisions, Distribution Of Moving Picture Or The Like (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK18696A 1989-12-22 1996-02-01 Peptides having tachykinin antagonist activity a process for preparation thereof and pharmaceutical compositions comprising the same HK18696A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898929070A GB8929070D0 (en) 1989-12-22 1989-12-22 Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same

Publications (1)

Publication Number Publication Date
HK18696A true HK18696A (en) 1996-02-09

Family

ID=10668423

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18696A HK18696A (en) 1989-12-22 1996-02-01 Peptides having tachykinin antagonist activity a process for preparation thereof and pharmaceutical compositions comprising the same

Country Status (21)

Country Link
US (1) US5468731A (ko)
EP (1) EP0443132B1 (ko)
JP (1) JP2560919B2 (ko)
KR (1) KR0180223B1 (ko)
CN (2) CN1034869C (ko)
AT (1) ATE98651T1 (ko)
AU (1) AU640185B2 (ko)
CA (1) CA2032864C (ko)
DE (1) DE69005286T2 (ko)
DK (1) DK0443132T3 (ko)
ES (1) ES2060910T3 (ko)
FI (1) FI93548C (ko)
GB (1) GB8929070D0 (ko)
HK (1) HK18696A (ko)
HU (2) HUT56581A (ko)
IE (1) IE64570B1 (ko)
NO (1) NO177535C (ko)
PT (1) PT96324B (ko)
RU (1) RU2055078C1 (ko)
UA (1) UA27254C2 (ko)
ZA (1) ZA909901B (ko)

Families Citing this family (87)

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WO1994004494A1 (en) * 1992-08-13 1994-03-03 Warner-Lambert Company Tachykinin antagonists
US5420297A (en) * 1990-10-24 1995-05-30 Fujisawa Pharmaceutical Co., Ltd. Peptides having substance P antagonistic activity
US5610140A (en) * 1991-04-01 1997-03-11 Cortech, Inc. Bradykinin receptor antagonists with neurokinin receptor blocking activity
US5472978A (en) * 1991-07-05 1995-12-05 Merck Sharp & Dohme Ltd. Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
US5654400A (en) * 1991-10-04 1997-08-05 Fujisawa Pharmaceutical Co., Ltd. Process for making peptide compounds having tachykinin antagonistic activity
ATE161821T1 (de) * 1991-11-12 1998-01-15 Pfizer Azyklische ethylendiaminderivate als 'substance p rezeptor' antagonisten
GB9200535D0 (en) * 1992-01-10 1992-02-26 Fujisawa Pharmaceutical Co New compound
HUT70475A (en) * 1992-09-03 1995-10-30 Boehringer Ingelheim Kg New aminoacid derivates, process for producing the same and pharmaceutical compositions containing these compounds
DE4243496A1 (de) * 1992-09-03 1994-03-10 Boehringer Ingelheim Kg Neue Dipeptidderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
FR2700472B1 (fr) 1993-01-19 1995-02-17 Rhone Poulenc Rorer Sa Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.
WO1994020126A1 (en) * 1993-03-03 1994-09-15 Fujisawa Pharmaceutical Co., Ltd. Use of peptides for the manufacture of a medicament
WO1995000536A1 (en) * 1993-06-22 1995-01-05 Fujisawa Pharmaceutical Co., Ltd. Peptide compounds
KR960703621A (ko) * 1993-08-10 1996-08-31 후지야마 아키라 경피흡수 제제(Percutaneously absorbable preparation)
JP3971454B2 (ja) * 1993-10-29 2007-09-05 ザ トラスティーズ オブ ボストン ユニバーシティ 抗新生物剤としての酪酸、酪酸塩、および誘導体の生理学的に安定な組成物
US6403577B1 (en) 1993-11-17 2002-06-11 Eli Lilly And Company Hexamethyleneiminyl tachykinin receptor antagonists
ITFI940009A1 (it) * 1994-01-19 1995-07-19 Menarini Farma Ind Antagonisti delle tachichinine, loro preparazione e formulazioni farmaceutiche che li contengono.
DE69519182T2 (de) * 1994-03-17 2001-05-17 Fujirebio Inc., Tokio/Tokyo Azapeptid-Derivate
FR2719312B1 (fr) * 1994-04-28 1996-06-14 Adir Nouveau pseudopeptides dérivés de neurokinines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
CA2189764A1 (en) * 1994-05-07 1995-11-16 Gerd Schnorrenberg Neurokinine (tachykinine) antagonists
FR2728169A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales
FR2728165A1 (fr) 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene
FR2728166A1 (fr) 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
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FR2741262B1 (fr) 1995-11-20 1999-03-05 Oreal Utilisation d'un antagoniste de tnf-alpha pour le traitement des rougeurs cutanees d'origine neurogene
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Also Published As

Publication number Publication date
CA2032864C (en) 2003-05-06
PT96324A (pt) 1991-09-30
CN1034869C (zh) 1997-05-14
GB8929070D0 (en) 1990-02-28
CA2032864A1 (en) 1991-06-23
IE904581A1 (en) 1991-07-03
DE69005286T2 (de) 1994-04-21
JPH04210996A (ja) 1992-08-03
RU2055078C1 (ru) 1996-02-27
UA27254C2 (uk) 2000-08-15
ZA909901B (en) 1991-10-30
NO177535B (no) 1995-06-26
JP2560919B2 (ja) 1996-12-04
FI93548C (fi) 1995-04-25
NO177535C (no) 1995-10-04
CN1064080A (zh) 1992-09-02
DE69005286D1 (de) 1994-01-27
ATE98651T1 (de) 1994-01-15
PT96324B (pt) 1998-10-30
EP0443132B1 (en) 1993-12-15
IE64570B1 (en) 1995-08-23
FI906204A (fi) 1991-06-23
HUT56581A (en) 1991-09-30
HU211558A9 (en) 1995-12-28
FI906204A0 (fi) 1990-12-17
AU640185B2 (en) 1993-08-19
FI93548B (fi) 1995-01-13
NO905572L (no) 1991-06-24
HU908443D0 (en) 1991-07-29
CN1159949A (zh) 1997-09-24
DK0443132T3 (da) 1994-01-24
ES2060910T3 (es) 1994-12-01
EP0443132A1 (en) 1991-08-28
KR0180223B1 (ko) 1999-04-01
KR910011891A (ko) 1991-08-07
US5468731A (en) 1995-11-21
NO905572D0 (no) 1990-12-21
AU6801090A (en) 1991-06-27

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20041212