HK1494A - Fluorinated benzyl triazole compounds - Google Patents
Fluorinated benzyl triazole compounds Download PDFInfo
- Publication number
- HK1494A HK1494A HK14/94A HK1494A HK1494A HK 1494 A HK1494 A HK 1494A HK 14/94 A HK14/94 A HK 14/94A HK 1494 A HK1494 A HK 1494A HK 1494 A HK1494 A HK 1494A
- Authority
- HK
- Hong Kong
- Prior art keywords
- carbamoyl
- triazole
- chlorine
- formula
- alkylcarbamoyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C247/00—Compounds containing azido groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH166385 | 1985-04-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1494A true HK1494A (en) | 1994-01-14 |
Family
ID=4215715
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK14/94A HK1494A (en) | 1985-04-18 | 1994-01-06 | Fluorinated benzyl triazole compounds |
Country Status (22)
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3578499D1 (de) * | 1984-02-02 | 1990-08-09 | Merck & Co Inc | 5-(amino oder substituiertes amino)-1,2,3-triazole. |
| WO1997040025A1 (en) * | 1996-04-19 | 1997-10-30 | Novo Nordisk A/S | Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles |
| NZ333505A (en) * | 1996-07-11 | 2000-06-23 | Novartis Ag | Preparing 1-substituted 4-cyano-1,2,3-triazoles using 4-cyano-1-(2,6-difuorobenzyl)-1H-1,2,3-triazole |
| TW526195B (en) | 1997-06-10 | 2003-04-01 | Novartis Ag | Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use |
| TW513301B (en) * | 1999-03-01 | 2002-12-11 | Novartis Ag | Pharmaceutical composition for treatment of neuropathic pain and affective and attention disorders |
| WO2004106329A2 (en) * | 2003-06-03 | 2004-12-09 | Dr. Reddy's Laboratories Ltd. | Novel antiinfective compounds and their pharmaceutical compositions |
| IT1393368B1 (it) * | 2009-03-23 | 2012-04-20 | Dipharma Francis Srl | Metodo per la preparazione di rufinamide |
| IT1395736B1 (it) | 2009-08-04 | 2012-10-19 | Dipharma Francis Srl | Forme cristalline di rufinamide |
| JP2013525413A (ja) * | 2010-04-30 | 2013-06-20 | ラボラトリオス レスヴィ，エス．エル． | ルフィナマイド中間体の改良された製造方法 |
| ITMI20110718A1 (it) | 2011-04-29 | 2012-10-30 | Dipharma Francis Srl | Procedimento per la purificazione di rufinamide |
| WO2014120994A1 (en) * | 2013-01-31 | 2014-08-07 | The Johns Hopkins University | Rufinamide and derivatives and their use in modulating the gating process of human voltage-gated sodium channels |
| US9771335B2 (en) * | 2015-07-31 | 2017-09-26 | The Johns Hopkins University | Derivatives of rufinamide and their use in inhibtion of the activation of human voltage-gated sodium channels |
| JP7016169B2 (ja) | 2015-12-11 | 2022-02-04 | オーフス ウニベルシテット | 筋強直症の治療における使用のためのルフィナミド |
| WO2021099481A1 (en) | 2019-11-20 | 2021-05-27 | Medichem, S.A. | Solid composition containing rufinamide |
| CN116874438A (zh) * | 2023-06-02 | 2023-10-13 | 大连理工大学 | 一锅法制备多取代1,2,3-三唑类化合物 |
| CN116854644A (zh) * | 2023-07-06 | 2023-10-10 | 浙江大学 | 5-氨基-1-烷基-1h-1,2,3-三氮唑-4-甲酰胺类化合物及其制备和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1511195A (en) * | 1976-10-18 | 1978-05-17 | Ici America Inc | Triazole derivatives |
| FI834666A7 (fi) * | 1982-12-23 | 1984-06-24 | Ciba Geigy Ag | Foerfarande foer framstaellning av nya aralkyltriazolfoereningar. |
-
1986
- 1986-04-14 PH PH33651A patent/PH22568A/en unknown
- 1986-04-14 FI FI861573A patent/FI93544C/fi not_active IP Right Cessation
- 1986-04-15 EP EP86105188A patent/EP0199262B1/de not_active Expired - Lifetime
- 1986-04-15 IL IL78510A patent/IL78510A/xx not_active IP Right Cessation
- 1986-04-15 DE DE8686105188T patent/DE3677626D1/de not_active Expired - Lifetime
- 1986-04-16 NO NO861486A patent/NO164295C/no unknown
- 1986-04-16 CA CA000506774A patent/CA1272201A/en not_active Expired - Lifetime
- 1986-04-16 GR GR861004A patent/GR861004B/el unknown
- 1986-04-16 ES ES554024A patent/ES8800176A1/es not_active Expired
- 1986-04-16 DD DD86289243A patent/DD245874A5/de not_active IP Right Cessation
- 1986-04-16 PT PT82400A patent/PT82400B/pt unknown
- 1986-04-17 KR KR1019860002954A patent/KR900008810B1/ko not_active Expired
- 1986-04-17 DK DK175686A patent/DK169720B1/da not_active IP Right Cessation
- 1986-04-17 ZA ZA862873A patent/ZA862873B/xx unknown
- 1986-04-17 AU AU56319/86A patent/AU599024B2/en not_active Expired
- 1986-04-17 IE IE101586A patent/IE58472B1/en not_active IP Right Cessation
- 1986-04-17 NZ NZ215871A patent/NZ215871A/xx unknown
- 1986-04-17 HU HU861615A patent/HU203327B/hu unknown
- 1986-04-18 JP JP61088384A patent/JPS61243068A/ja active Granted
-
1987
- 1987-07-31 ES ES557641A patent/ES8802501A1/es not_active Expired
-
1992
- 1992-06-26 MX MX9203628A patent/MX9203628A/es unknown
-
1994
- 1994-01-06 HK HK14/94A patent/HK1494A/xx not_active IP Right Cessation
- 1994-06-03 CY CY175194A patent/CY1751A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1494A (en) | Fluorinated benzyl triazole compounds | |
| JP2015520203A (ja) | Ｌｐａｒ拮抗薬としてのｎ−アリールトリアゾール化合物 | |
| EP0442820A1 (fr) | Nouveaux dérivés de benzimidazole et d'azabenzimidazole, antagonistes des récepteurs au thromboxane; leurs procédés de préparation, intermédiaires de synthèse, compositions les contenant | |
| OA10142A (fr) | Dérivés de lipopeptide procédé pour leur préparation médicaments les contenant et leur utilisation | |
| US3915980A (en) | Imidazolyl-(2)-thio-alkanoic acid esters | |
| US3523952A (en) | Process for preparing pyrryl-(2)-acetonitriles | |
| US3483248A (en) | Preparation of 2-(4-biphenylyl) butyric acid | |
| CA2566754C (en) | Process for the preparation of perindopril and salts thereof | |
| US3564010A (en) | Guanidino ureido and thioureido-delta**1-pyrrolines | |
| JPH0262551B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| US3917634A (en) | 1-(2,6-Dimethyl-2-octen-8-yl)-2-substituted or unsubstituted phenylimidazoles | |
| US4511577A (en) | Derivatives of benzoic acid | |
| CA1171090A (en) | 7-(2,6-dibromo-4-methylphenyl)-2,3-dihydro- imidazo[1,2-a]imidazoles, the acid addition salts thereof, pharmaceutical compositions containing them and processes for the preparation thereof | |
| CA1062267A (en) | Process for the preparation of 1-benxoyl-2-(2',6'-dichlorophenylamino)-2-imidazoline and salts thereof | |
| US20060035913A1 (en) | Method for the production of 2-amino-4-chloro-6-alkoxypyrimidines | |
| LU82434A1 (fr) | Procede de preparation de derives condenses de la pyrimidine,les sels,hydrates et isomeres de ceux-ci,certains representants de ces composes prepares et compositions pharmaceutiques contenant ceux-ci | |
| US3812170A (en) | N-(3,3-diphenyl-3-cyanopropyl)-ureas | |
| US3772413A (en) | 1-cyano-2-imino-3,3-diphenylpyrrolidines | |
| SE460969B (sv) | Apovincaminsyraderivat, foerfarande foer framstaellning daerav och farmaceutiska kompositioner innehaallande dessa derivat | |
| US4888352A (en) | 3,4, or 5-aryl-1H-pyrazole-1-alkanamides as antiarrhythmic agents, compositions and use | |
| US4301170A (en) | 1-Dimethyl substituted alkyl-2-or 4-substituted phenylimidazoles | |
| US4421756A (en) | Quinolinoneimine carboxylic acid anti-inflammatory and analgesic composition containing the compound | |
| US3880917A (en) | 2-Oxo-3,4-benzobicyclo-(3,3,1)-nonene-(3) carboxylic acids-8 thereof and process therefor | |
| RU2124504C1 (ru) | СПОСОБ ПОЛУЧЕНИЯ 5H-ДИБЕНЗ[b,F]АЗЕПИН-5-КАРБОКСАМИДА | |
| EP0002649A2 (en) | 1-Dimethyl-substituted alkyl-2- or 4-substituted phenylimidazoles, their production and their use as anti-obesity agents |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PF | Patent in force | ||
| PE | Patent expired |
Effective date: 20060414 |