HK134693A - Agents for blocking endothelin derived relaxing factor - Google Patents

Agents for blocking endothelin derived relaxing factor Download PDF

Info

Publication number
HK134693A
HK134693A HK1346/93A HK134693A HK134693A HK 134693 A HK134693 A HK 134693A HK 1346/93 A HK1346/93 A HK 1346/93A HK 134693 A HK134693 A HK 134693A HK 134693 A HK134693 A HK 134693A
Authority
HK
Hong Kong
Prior art keywords
agents
relaxing factor
derived relaxing
endothelin
blocking
Prior art date
Application number
HK1346/93A
Other languages
English (en)
Inventor
Braquet Pierre
Chabrier De Lassauniere Pierre-Etienne
Guillon Jean-Michel
Auguet Michel
Original Assignee
Societe De Conseils De Recherches Et D'applications Scientifiques (S C R A S)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe De Conseils De Recherches Et D'applications Scientifiques (S C R A S) filed Critical Societe De Conseils De Recherches Et D'applications Scientifiques (S C R A S)
Publication of HK134693A publication Critical patent/HK134693A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK1346/93A 1989-12-22 1993-12-09 Agents for blocking endothelin derived relaxing factor HK134693A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898929076A GB8929076D0 (en) 1989-12-22 1989-12-22 Treatment of shock by blocking agents of edrf effect or formation

Publications (1)

Publication Number Publication Date
HK134693A true HK134693A (en) 1993-12-17

Family

ID=10668428

Family Applications (1)

Application Number Title Priority Date Filing Date
HK1346/93A HK134693A (en) 1989-12-22 1993-12-09 Agents for blocking endothelin derived relaxing factor

Country Status (21)

Country Link
US (1) US5081148A (enExample)
JP (1) JP2706578B2 (enExample)
KR (1) KR950005866B1 (enExample)
AT (1) AT403122B (enExample)
AU (1) AU629777B2 (enExample)
BE (1) BE1005531A5 (enExample)
CA (1) CA2032904C (enExample)
CH (1) CH681692A5 (enExample)
DE (1) DE4041283C2 (enExample)
DK (1) DK176168B1 (enExample)
FR (1) FR2656220B1 (enExample)
GB (2) GB8929076D0 (enExample)
HK (1) HK134693A (enExample)
IE (1) IE64403B1 (enExample)
IT (1) IT1246511B (enExample)
LU (1) LU87867A1 (enExample)
MY (1) MY105328A (enExample)
NL (1) NL194717C (enExample)
OA (1) OA09337A (enExample)
SE (1) SE504922C2 (enExample)
ZA (1) ZA9010004B (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE468881B (sv) * 1991-01-09 1993-04-05 Kabi Pharmacia Ab Anvaendning av vissa foereningar foer framstaellning av laekemedel foer behandling av endotoxininducerade effekter samt saett att avlaegsna endotoxiner ur diverse loesningar
GB9127376D0 (en) * 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
GB9200114D0 (en) * 1992-01-04 1992-02-26 Scras Dual inhibitors of no synthase and cyclooxygenase
US5385940A (en) * 1992-11-05 1995-01-31 The General Hospital Corporation Treatment of stroke with nitric-oxide releasing compounds
US5585402A (en) * 1992-12-23 1996-12-17 Glaxo Wellcome Inc. Nitric oxide synthase inhibitors
US5436270A (en) * 1993-04-07 1995-07-25 National Science Council Method for protecting against endotoxin-induced shock
GB9312204D0 (en) * 1993-06-14 1993-07-28 Zeneca Ltd Therapeutic composition
GB9312761D0 (en) * 1993-06-21 1993-08-04 Wellcome Found Amino acid derivatives
US6090846A (en) * 1994-06-01 2000-07-18 Glaxo Wellcome Inc. Substituted urea and isothiourea derivatives as no synthase inhibitors
US6297276B1 (en) 1993-10-04 2001-10-02 Glaxosmithkline Substituted urea and isothiourea derivatives as no synthase inhibitors
US6225305B1 (en) 1993-10-04 2001-05-01 Glaxo Wellcome Inc. Substituted urea and isothiorea derivatives as no synthase inhibitors
AU688811B2 (en) * 1993-10-21 1998-03-19 G.D. Searle & Co. Amidino derivatives useful as nitric oxide synthase inhibitors
CA2170735A1 (en) * 1993-10-21 1995-04-27 Foe S. Tjoeng Amidino derivatives useful as nitric oxide synthase inhibitors
GB9404400D0 (en) * 1994-03-07 1994-04-20 Wood Pauline J Potentiation of bioreductive agents
EP0749418B1 (en) * 1994-03-10 2000-08-30 G.D. Searle & Co. L-n6 -(1-iminoethyl)lysine derivatives useful as nitric oxide synthase inhibitors
US5684008A (en) * 1994-11-09 1997-11-04 G. D. Searle & Co. Aminotetrazole derivatives useful as nitric oxide synthase inhibitors
FR2727111B1 (fr) * 1994-11-21 1997-01-17 Hoechst Lab Nouveaux analogues soufres d'aminoacides, leur procede de preparation et leurs applications comme medicaments
CN1160115C (zh) * 1994-12-12 2004-08-04 奥默罗斯公司 用于抑制疼痛,炎症和痉挛的冲洗液和方法
KR100517210B1 (ko) * 1994-12-12 2006-06-07 오메로스 코포레이션 통증,염증및경련억제용관주용액
FR2730930B1 (fr) 1995-02-27 1997-04-04 Oreal Utilisation d'inhibiteurs de no-synthase pour diminuer l'effet irritant cutane de produits utilises dans le domaine cosmetique ou pharmaceutique
GB9504350D0 (en) * 1995-03-04 1995-04-26 Sod Conseils Rech Applic Arginine derivatives
BR9608012A (pt) * 1995-04-20 1999-01-05 Searle & Co Agentes de amidino cíclicos úteis como inbidores da sintase do óxido nítrico
US5830917A (en) * 1995-09-11 1998-11-03 G. D. Searle & Co. L-N6 -(1-iminoethyl) lysine derivatives useful as nitric oxide synthase inhibitors
BR9509985A (pt) * 1995-12-12 1998-11-03 Omeros Med Sys Inc Solução para irrigação e método para inibição de dor inflamação e esparmo
US5945408A (en) * 1996-03-06 1999-08-31 G.D. Searle & Co. Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors
US5981511A (en) * 1996-03-06 1999-11-09 G.D. Searle & Co. Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors
US6369272B1 (en) 1997-01-13 2002-04-09 Glaxosmithkline Nitric oxide synthase inhibitors
US6620848B2 (en) 1997-01-13 2003-09-16 Smithkline Beecham Corporation Nitric oxide synthase inhibitors
US5981556A (en) * 1997-07-22 1999-11-09 G.D. Searle & Co. 1,3-diazolino and 1,3-diazolidino heterocycles as useful nitric oxide synthase inhibitors
GB9811599D0 (en) 1998-05-30 1998-07-29 Glaxo Group Ltd Nitric oxide synthase inhibitors
JP2002517502A (ja) 1998-06-10 2002-06-18 ジー・ディー・サール・アンド・カンパニー 複素二環状及び三環状一酸化窒素シンターゼ阻害剤
US6344473B1 (en) 2000-08-07 2002-02-05 G.D. Searle & Co. Imidazoles useful as nitric oxide synthase inhibitors
JP4630820B2 (ja) 2003-12-30 2011-02-09 ヴァソファーム ゲーエムベーハー ４−アミノ−７，８−ジヒドロプテリジン類、これらを含む医薬組成物、および一酸化窒素レベル上昇によってもたらされる疾病の治療に対するそれらの使用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB931921A (en) * 1960-12-22 1963-07-24 Lab Roques Therapeutic compositions intended for the treatment of any hepatic malfunctionings
GB1195612A (en) * 1967-04-13 1970-06-17 Sumitomo Chemical Co An Injection
FR2115060A1 (en) * 1970-11-26 1972-07-07 Metabio Freeze-dried acetylsalicylates of lysine and arginine - easily prepd derivs of aspirin
CA1029660A (en) * 1973-06-01 1978-04-18 Kyowa Hakko Kogyo Co. Prevention of gastric lesions
FR2320759A1 (fr) * 1975-08-11 1977-03-11 Union Pharma Scient Appl Solution d'acide acetylsalicylique extemporanee injectable
IT1127322B (it) * 1979-12-28 1986-05-21 Italfarmaco Spa Composizioni farmaceutiche con esaltazione dell'attivita' terapeutica di cortisonici
IT1127321B (it) * 1979-12-28 1986-05-21 Italfarmaco Spa Composizione farmaceutiche aventi specifiche proprieta' terapeutiche nei confronti dell'edema polmonare acuto,di alcuni stati di shock e dell'iperfibrinolisi
JPS5781409A (en) * 1980-11-10 1982-05-21 Toko Yakuhin Kogyo Kk External plaster
JPS57197211A (en) * 1981-05-28 1982-12-03 Sumitomo Chem Co Ltd Useful eye drop composition
JPS57200361A (en) * 1981-06-03 1982-12-08 Sumitomo Chem Co Ltd "indomethacin(r)" pharmaceutical with low irritant action
JPS6239524A (ja) * 1985-08-13 1987-02-20 Toko Yakuhin Kogyo Kk 消炎鎮痛軟膏剤
JPH0236570B2 (ja) * 1985-05-30 1990-08-17 Toko Yakuhin Kogyo Kk Shoenchintsunankozai
IT1201511B (it) * 1985-12-23 1989-02-02 Italfarmaco Spa Derivati citoprotettivi in patologie a base ischemica,loro preparazione e composizioni che li cntengono
EP0310639B1 (en) * 1987-02-20 1993-03-03 Shriners Hospitals For Crippled Children Omega-3 fatty acids in traumatic injury treatment

Also Published As

Publication number Publication date
DK176168B1 (da) 2006-11-13
JP2706578B2 (ja) 1998-01-28
NL194717B (nl) 2002-09-02
DK304190D0 (da) 1990-12-21
IE64403B1 (en) 1995-08-09
DE4041283C2 (de) 2000-07-13
KR950005866B1 (ko) 1995-06-02
GB2240041B (en) 1993-09-01
CA2032904A1 (en) 1991-06-23
IT9022413A0 (it) 1990-12-18
AU629777B2 (en) 1992-10-08
CH681692A5 (enExample) 1993-05-14
SE9003974D0 (sv) 1990-12-12
KR910011253A (ko) 1991-08-07
GB2240041A (en) 1991-07-24
ATA260690A (de) 1997-04-15
NL194717C (nl) 2003-01-07
IT1246511B (it) 1994-11-19
DE4041283A1 (de) 1991-06-27
SE504922C2 (sv) 1997-05-26
DK304190A (da) 1991-06-23
IT9022413A1 (it) 1991-06-23
CA2032904C (en) 1996-01-02
MY105328A (en) 1994-09-30
NL9002720A (nl) 1991-07-16
AU6837690A (en) 1991-06-27
FR2656220B1 (fr) 1995-01-13
SE9003974L (sv) 1991-06-23
ZA9010004B (en) 1991-10-30
US5081148A (en) 1992-01-14
IE904592A1 (en) 1991-07-03
BE1005531A5 (fr) 1993-09-28
FR2656220A1 (fr) 1991-06-28
AT403122B (de) 1997-11-25
JPH04364124A (ja) 1992-12-16
OA09337A (fr) 1992-09-15
LU87867A1 (fr) 1991-05-07
GB8929076D0 (en) 1990-02-28
GB9028013D0 (en) 1991-02-13

Similar Documents

Publication Publication Date Title
HK134693A (en) Agents for blocking endothelin derived relaxing factor
PT100631A (pt) Antagonistas biciclicos de fibrinogenio, seu uso e composicoes farmaceuticas que os contem
CA2113229A1 (en) Anti-fibrotic quinazolinone-containing compositions and methods for the use thereof
AU7077894A (en) Immunosuppressant and antiallergic compounds, e.g. n-(3-oxohexanoyl) homoserine lactone
FI940696A0 (fi) Uudet pyratsiinijohdannaiset, niiden valmistus ja käyttö
DE69413393D1 (de) In 15-stellung substituierte 4-azasteroide
EP0765865A4 (en) 2-ACYLAMINOPROPANOL COMPOUND AND MEDICINAL COMPOSITION
CA2444071A1 (en) Oxypurine nucleosides and their congeners, and acyl derivatives thereof, for improvement of hematopoiesis
ES8701193A1 (es) Un procedimiento para preparar derivados de acido griseolico
CA2207097A1 (en) Quinazolinone-containing pharmaceutical compositions and methods for the use thereof
BR1100143A (pt) Composto, e, composição farmacêutica.
IL111966A0 (en) 4-Benzoylisoxazole derivatives, their preparation and herbicidal compositions containing them
DE69330601D1 (de) Serotoninergische ergolin derivate
DE69226931D1 (de) Guanidinothiazolederivate und ihre Anwendung als H2-Rezeptor-Antagonisten
NZ240441A (en) Thiazol- or thiadiazol-substituted 7-acyl-3-substituted carbamoyloxy cephem derivatives and antibacterial compositions thereof; cephem intermediates
JPS55113723A (en) Drug composition to be absorbed in digestive canal
BR9202709A (pt) Composicao,processo para aperfeicoar as propriedades de uso de lubrificantes e compostos
JPS5424895A (en) Pyranochromone derivatives and remedies for allergic disorder
BR9507976A (pt) Mistura fungicida processo para controlar fungos nocivos e uso de um composto
KR910009723A (ko) 4-카르바모일-1-β-D-리보푸라노실 이미다졸륨-5-올레이트 무수결정
IE820238L (en) Carbapenem derivatives
DK0567767T3 (da) Krystallinske former af endo-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H-benzimidazol-1-carboxamid-hydroc
ATE94551T1 (de) Antibakterielles mittel fuer anwendung bei saeugetieren mit cephalosporinverbindungen als effektiven bestandteil.
MX9305995A (es) Compuestos de carboniloxialpirrol n-sustituidos y composicion paracontrolar insectos, acaridos y moluscos que los contienen.
HK31784A (en) Pyridone disperse dyestuffs

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)